• Title/Summary/Keyword: deviation analysis

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Measurement of Optical Purity for Commercially Avialable Naproxen Sold in 2013 (2013년 시판된 나프록센의 광학순도 측정)

  • Seo, Hae Chan;Song, Jung Suk;Ryoo, Sang Hyun;Lee, Sang Heon;Ryoo, Dong Hyun;Yu, Jeong Jae;Ryoo, Jae Jeong
    • Journal of the Korean Chemical Society
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    • v.58 no.2
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    • pp.179-185
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    • 2014
  • Commercial (S)-naproxen was racemized under strong basic condition. After checking the peak position of (R)- and (S)-naproxen by analysis the recemized naproxen, optical purity of 19 commercialized naproxens sold in 2013 in Korea were examined by chiral HPLC. The Chiralcel OD-H column, ChiralHyun-LE(S)-1 column and LUX-Cellulose-1 column were used as chiral stationary phases and the mixed eluent of hexane:isopropanol:acetic acid as 100:1:0.1 was used as a mobile phase with a flow rate of 1.0 mL/min. Each data was obtained from an average value of at least three different experiments for each sample and the relative standard deviation of them appeared very small. The average optical purity values obtained from three different chiral columns were very similar and the total average optical purity value (99.32%) of nineteen commercialized naproxens used in this study were larger than those of three years ago (98.17%).

A Study On RTLS(Real Time Location System) Based on RSS(Received Signal Strength) and RSS Characteristics Analysis with the External Factors (외적요인에 따른 RSS 특성 분석과 이를 이용한 실시간 위치 추적 시스템 구현에 관한 연구)

  • Lee, Seung-Ho
    • Journal of IKEEE
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    • v.15 no.1
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    • pp.76-85
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    • 2011
  • In this paper, we analysed RSS characteristics by external factors and presented an efficient algorithm for real-time location tracking and its hardware system. The proposed algorithm enhanced the ranging accuracy using Kalman Filter based on the RSS DB. The location tracking system that consists of the tag, AP(Access Point), a data collector(Data Receiver) with IEEE 802.15.4(ZigBee) network environment, and location tracking application that reveal locations of each tag is implemented for the test environment. The location tracking system presented in this paper is implemented with MSP430 microprocessor manufactured by TI(Texas Instrument), CC2420 RF chipset and the location tracking application. With the results of the experiment, the proposed algorithm and the system can achieve the efficiency and the accuracy of location tracking with the average error of 19.12cm, and its standard deviation of 5.31cm in outdoor circumstance. Also, the experimental result shows that exact tracking of position in indoor circumstance cannot achieve because of vulnerable RSS with external circumstance.

A Study on the Effectiveness of the Exclusion Calculation for the Product Inclusive Design: A Case Study on the Evaluation of Electric Iron (제품의 포용적 디자인을 위한 Exclusion Calculation 평가 방법의 효용성 연구: 전기다리미 평가를 사례 연구로)

  • Zhang, Ji-Fa;Go, Jung-Wook
    • The Journal of the Korea Contents Association
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    • v.20 no.4
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    • pp.111-123
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    • 2020
  • It is very important to ensure usability and inclusion in product design and development. Exclusion Calculation, developed by Simon Keates and P. John Clarkson at Cambridge University's Engineering Design Center, assesses the usability and inclusiveness of the product. In context of inadequate research on effectiveness of Exclusion Calculation, this study carried out the experimental evaluation of electric iron and discussed the effectiveness of the Exclusion Calculation from usefulness, accuracy of its evaluation results and the intuitiveness of the evaluation items. 11 designers used Exclusion Calculation in product evaluation and estimated the intuitiveness of 14 evaluation items in Exclusion Calculation by questionnaire. Then usefulness of the evaluation results was discussed and the accuracy of the evaluation results was analyzed by standard deviation. From the evaluation results, the research found that Exclusion Calculation could help designers identify the usability problems and the generality of usability problems related to the physical characteristics of the products, but it can not find the problems from logical aspect of using. In addition, the ambiguity of the evaluation scale in Exclusion Calculation leads to lower accuracy of the evaluation results. Most of evaluation items in Exclusion Calculation were easy to be identified and judged, while evaluation items related to cognitive abilities are less intuitive.

Analysis of 3D Accuracy According to Determination of Calibration Initial Value in Close-Range Digital Photogrammetry Using VLBI Antenna and Mobile Phone Camera (VLBI 안테나와 모바일폰 카메라를 활용한 근접수치사진측량의 캘리브레이션 초기값 결정에 따른 3차원 정확도 분석)

  • Kim, Hyuk Gi;Yun, Hong Sik;Cho, Jae Myoung
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.33 no.1
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    • pp.31-43
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    • 2015
  • This study had been aimed to conduct the camera calibration on VLBI antenna in the Space Geodetic Observation Center of Sejong City with a low-cost digital camera, which embedded in a mobile phone to determine the three-dimension position coordinates of the VLBI antenna, based on stereo images. The initial values for the camera calibration have been obtained by utilizing the Direct Linear Transformation algorithm and the commercial digital photogrammetry system, PhotoModeler $Scanner^{(R)}$ ver. 6.0, respectively. The accuracy of camera calibration results was compared with that the camera calibration results, acquired by a bundle adjustment with nonlinear collinearity condition equation. Although two methods showed significant differences in the initial value, the final calibration demonstrated the consistent results whichever methods had been performed for obtaining the initial value. Furthermore, those three-dimensional coordinates of feature points of the VLBI antenna were respectively calculated using the camera calibration by the two methods to be compared with the reference coordinates obtained from a total station. In fact, both methods have resulted out a same standard deviation of $X=0.004{\pm}0.010m$, $Y=0.001{\pm}0.015m$, $Z=0.009{\pm}0.017m$, that of showing a high degree of accuracy in centimeters. From the result, we can conclude that a mobile phone camera opens up the way for a variety of image processing studies, such as 3D reconstruction from images captured.

Level of Knowledge and Attitude about Organ Donation in An University Students (장기기증에 대한 대학생들의 지식수준과 태도)

  • Park, Hwi-Hyang;Kim, Yeon-Joo;Kim, Jin-Hui;Park, Mi-Hyeon;Kim, Yeon-Gyeong;Kim, Yeon-Bin;Kim, Yoon-Seo;Kim, Ji-An;Min, Ji-Hyeon;Bae, Seong-Cheol;Kim, Jin-A;Ahn, Seong-Ah;Kim, Eun Hee
    • Journal of Korean Clinical Health Science
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    • v.3 no.1
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    • pp.299-310
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    • 2015
  • Purpose. The purpose of this study was to investigate level of knowledge and attitude about organ donation in university and provide basic information on correct education and promotion. Method. The sample is consisted of 90 the students related to health and 90 general college students ; total 180 students in J city. The questionnaires were used to obtain the results. Data was collected from November 6th to 8th, 2013. For data analysis, the SPSS for window 12.0 K program was utilized to get descriptive statistics including the percentage, average, standard deviation and t-test. Results. Comparing the results between a series of health students and general college students, a series of health students showed high level of more knowledge and more positive attitude about organ donation than general college students. A series of health showed significant correlation but general college didn't show significant correlation. Conclusion. To educate correct knowledge draw positive attitude about organ donation is needed to improve the level of Knowledge and Attitude about organ donation.

An analysis of problems and countermeasures in the installation of plastic greenhouse on reclaimed lands (간척지에 플라스틱 온실 설치 시의 문제점 분석 및 개선방안)

  • Yu, In-Ho;Ku, Yang-Gyu;Cho, Myeong-Whan;Ryu, Hee-Ryong;Moon, Doo-Gyung
    • Korean Journal of Agricultural Science
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    • v.41 no.4
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    • pp.473-480
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    • 2014
  • Upon setting up a dedicated plastic greenhouse for tomato cultivation developed by the Rural Development Administration on the Gyehwa reclaimed land, this study was aimed at analyzing the problems can be occurred in the installation of plastic greenhouse on reclaimed lands as well as finding out solutions for improvement. A relatively cheaper wooden pile was used in the installation in order to supplement the soft ground conditions. Based on the results of ground investigation of the installation site, both the allowable bearing capacity and pulling resistance of the wooden pile with a diameter of 150 mm and a length of 10 m were computed and came out to be 30.645 kN. It was determined that the values were enough to withstand the maximum compressive force (17.206 kN) and the pullout force (20.435 kN) that are generally applied to the greenhouse footing. There are three problems aroused in the process of greenhouse installation, and the corresponding countermeasures are as follow. First, due to the slightly bent shape of the wooden pile, there were phenomenon such as deviation, torsion, and fracture when driving the pile. This could be prevented by the use of the backhoe (0.2) rotating tongs, which are holding the pile, to drive the pile while pushing to the direction of the driving and fixing it until 5 m below ground and applying a soft vibrating pressure until the first 2 m. Second, there exists a concrete independent footing between the column of the greenhouse and the wooden pile driven to the underground water level. Since it is difficult to accurately drive the pile on this independent footing, the problem of footing baseplate used to fix the column being off the independent footing was occurred. In order to handle with this matter, the diameter of the independent footing was changed from 200 mm to 300 mm. Last, after films were covered in the condition that the reinforcing frame and bracing are not installed, there was a phenomenon of columns being pushed away by the strong wind to the maximum of $11m{\cdot}s^{-1}$. It is encouraged to avoid constructions in winter, and the film covering jobs always to be done after the frame construction is completely over. The height of the independent footing was measured for 9 months after the completion of the greenhouse installation, and it was found to be within the margin of error meaning that there was no subsidence. The extent to the framework distortion and the value of inclinometers as well showed not much alteration. In other words, the wooden pile was designed to have a sufficient bearing capacity.

Parameter Analysis for Time Reduction in Extracting SIFT Keypoints in the Aspect of Image Stitching (영상 스티칭 관점에서 SIFT 특징점 추출시간 감소를 위한 파라미터 분석)

  • Moon, Won-Jun;Seo, Young-Ho;Kim, Dong-Wook
    • Journal of Broadcast Engineering
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    • v.23 no.4
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    • pp.559-573
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    • 2018
  • Recently, one of the most actively applied image media in the most fields such as virtual reality (VR) is omni-directional or panorama image. This image is generated by stitching images obtained by various methods. In this process, it takes the most time to extract keypoints necessary for stitching. In this paper, we analyze the parameters involved in the extraction of SIFT keypoints with the aim of reducing the computation time for extracting the most widely used SIFT keypoints. The parameters considered in this paper are the initial standard deviation of the Gaussian kernel used for Gaussian filtering, the number of gaussian difference image sets for extracting local extrema, and the number of octaves. As the SIFT algorithm, the Lowe scheme, the originally proposed one, and the Hess scheme which is a convolution cascade scheme, are considered. First, the effect of each parameter value on the computation time is analyzed, and the effect of each parameter on the stitching performance is analyzed by performing actual stitching experiments. Finally, based on the results of the two analyses, we extract parameter value set that minimize computation time without degrading.

HPLC Method for Simultaneous Quantitative Detection of Quercetin and Curcuminoids in Traditional Chinese Medicines

  • Ang, Lee Fung;Yam, Mun Fei;Fung, Yvonne Tan Tze;Kiang, Peh Kok;Darwin, Yusrida
    • Journal of Pharmacopuncture
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    • v.17 no.4
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    • pp.36-49
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    • 2014
  • Objectives: Quercetin and curcuminoids are important bioactive compounds found in many herbs. Previously reported high performance liquid chromatography ultraviolet (HPLC-UV) methods for the detection of quercetin and curcuminoids have several disadvantages, including unsatisfactory separation times and lack of validation according the standard guidelines of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use. Methods: A rapid, specific, reversed phase, HPLC-UV method with an isocratic elution of acetonitrile and 2% v/v acetic acid (40% : 60% v/v) (pH 2.6) at a flow rate of 1.3 mL/minutes, a column temperature of $35^{\circ}C$, and ultraviolet (UV) detection at 370 nm was developed. The method was validated and applied to the quantification of different types of market available Chinese medicine extracts, pills and tablets. Results: The method allowed simultaneous determination of quercetin, bisdemethoxycurcumin, demethoxycurcumin and curcumin in the concentration ranges of $0.00488-200{\mu}g/mL$, $0.625-320{\mu}g/mL$, $0.07813-320{\mu}g/mL$ and $0.03906-320{\mu}g/mL$, respectively. The limits of detection and quantification, respectively, were 0.00488 and $0.03906{\mu}g/mL$ for quercetin, 0.62500 and $2.50000{\mu}g/mL$ for bisdemethoxycurcumin, 0.07813 and $0.31250{\mu}g/mL$ for demethoxycurcumin, and 0.03906 and $0.07813{\mu}g/mL$ for curcumin. The percent relative intra day standard deviation (% RSD) values were $0.432-0.806{\mu}g/mL$, $0.576-0.723{\mu}g/mL$, $0.635-0.752{\mu}g/mL$ and $0.655-0.732{\mu}g/mL$ for quercetin, bisdemethoxycurcumin, demethoxycurcumin and curcumin, respectively, and those for intra day precision were $0.323-0.968{\mu}g/mL$, $0.805-0.854{\mu}g/mL$, $0.078-0.844{\mu}g/mL$ and $0.275-0.829{\mu}g/mL$, respectively. The intra day accuracies were 99.589%-100.821%, 98.588%-101.084%, 9.289%-100.88%, and 98.292%-101.022% for quercetin, bisdemethoxycurcumin, demethoxycurcumin and curcumin, respectively, and the inter day accuracy were 99.665%-103.06%, 97.669%-103.513%, 99.569%-103.617%, and 97.929%-103.606%, respectively. Conclusion: The method was found to be simple, accurate and precise and is recommended for routine quality control analysis of commercial Chinese medicine products containing the flour flavonoids as their principle components in the extracts.

Three dimensional accuracy analysis of dental stone casts fabricated using irreversible hydrocolloid impressions (알지네이트 인상체에서 제작된 치과용 석고 모형의 정확도에 대한 삼차원 디지털 분석)

  • Joo, Young-Hun;Lee, Jin-Han
    • Journal of Dental Rehabilitation and Applied Science
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    • v.31 no.4
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    • pp.316-328
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    • 2015
  • Purpose: The objects of this study was to evaluate the accuracy of the dental stone casts made from alginate impressions according to storage condition and stone pouring time. Materials and Methods: Each of upper and lower impressions of dental model was taken. The dental stone models were made immediately, 10, 30, 60, 180, 360 minutes after the impressions were taken at each storage condition. 3D models were constructed by scanning the stone model using 3D laser scanner. With Reference points, positioned on digital models, linear measurements of the dimensional change were compared by 3D metrology software, 3D average models were made and superimposition to identify the specific site of dimensional change and to measure surface deviation (mm). Results: Dental stone models which were made immediately after taking the impression showed the smallest linear dimensional change. As the stone pouring time was prolonged, the linear dimensional change was increased. More than 180 minutes after impression taking, linear dimensional change and surface distortion increased in the posterior molar region, regardless of the storage condition. Conclusion: For the optimum accuracy of the dental stone casts, alginate impression should be poured as soon as possible. If there were a need for storing, a humidor with 100% relative humidity must be used and be stored less than 180 minutes to fabricate the accurate dental model.

A Study on Inflow Rate According to Shape of Dual Structure Perforated Pipe Applied to Seawater Intake System (해수취수시스템에 적용된 2중구조 유공관의 형태에 따른 취수효율에 대한 연구)

  • Kim, Sooyoung;Lee, Seung Oh
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.6
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    • pp.721-728
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    • 2016
  • 97% of water on earth exists in the form of seawater. Therefore, the use of marine resources is one of the most important research issues at present. The use of seawater is expanding in various fields (seawater desalination, cooling water for nuclear power plants, deep seawater utilization, etc.). Seawater intake systems utilizing sand filters in order to take in clean seawater are being actively employed. For the intake pipe used in this system, assuring equal intake flows through the respective holes is very important to improve the efficiency of the intake and filtering process. In this study, we analyzed the efficiency of the dual structure perforated pipe used in the seawater intake system using 3D numerical simulations and the inflow rate according to the gap of the up holes. In the case of decreasing gaps in the up holes toward the pipe end, the variation of the total inflow rate was small in comparison with the other cases. However, the standard deviation of the inflow rate through the up holes was the lowest in this case. Also, stable flow occurred, which can improve the efficiency of the intake process. In the future, a sensitivity analysis of the various conditions should be performed based on the results of this study, in order to determine the factors influencing the efficiency, which can then be utilized to derive optimal designs suitable for specific environments.