• 제목/요약/키워드: developmental difference

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Change of X Chromosome Status during Development and Reprogramming

  • Jung, Yong-Wook;Park, In-Hyun
    • 한국발생생물학회지:발생과생식
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    • 제15권3호
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    • pp.187-195
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    • 2011
  • X chromosome inactivation (XCI) is a process that enables mammalian females to ensure the dosage compensation for X-linked genes. Investigating the mechanism of XCI might provide deeper understandings of chromosomal silencing, epigenetic regulation of gene expressions, and even the course of evolution. Studies on mammalian XCI conducted with mice have revealed many fundamental findings on XCI. However, difference of murine and human XCI necessitates the further investigation in human XCI. Recent success in reprogramming of differentiated cells into pluripotent stem cells showed the reversibility of XCI in vitro, X chromosome reactivation (XCR), which provides another tool to study the change in X chromosome status. This review summarizes the current knowledge of XCI during early embryonic development and describes recent achievements in studies of XCI in reprogramming process.

백서(白鼠)의 구치부기능상실(臼齒部機能喪失)이 과두발육(顆頭發育)에 미치는 영향(影響)에 관(關)한 실험적(實驗的) 연구(硏究) (EXPERIMENTAL STUDY OF THE EFFECT ON THE RAT'S CONDYLAR DEVELOPMENT WITH THE LOSS OF FUNCTION IN MOLAR)

  • 김재형
    • 대한치과교정학회지
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    • 제9권1호
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    • pp.111-115
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    • 1979
  • The author intended to observe the developmental pattern in mandibular bone and condyle following the loss of function of molar with 5 week-old rats b y means of removing the crown of molar. The bjects were observed everyweek during six weeks. The results were as follows ; 1. Bone apposition was observed at the root apex and interadicular area of alveolar bone. 2. Development of bone substance in mandible tended to increase in the narrow bone trabeculae and fibrous bone substance. 3. Development of condylar head showed little difference from that of control group and development of calcified zone appeared more or less poorly.

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은행나무 유식물에 있어서 반응조직의 분화에 대한 해부학적 연구 (Anatomical Studies on the Differentiation of Reaction Tissues in Ginkgo biloba L. Seedling)

  • 강경덕
    • Journal of Plant Biology
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    • 제33권4호
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    • pp.285-292
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    • 1990
  • In order to elucidate the formation of reaction tissues during the transition from primary to secondary growth, the developmental anatomy was conducted in the first internode of Ginkgo biloba seedling in horizontal position. The righting of the horizontal first internode took place at the middle portion and gradually proceeded to the base during the primary growth. Reaction tissues were formed corresponding to the righting movement in the horizontal first internode. During the transition from primary to secondary growth, compression wood was gradually developed on the lower side only. The anatomical features of compression wood also extended longitudinally to the lower side of the vertical portion where it coincided with the lower side of the horizontal first internode occurs acropetally from basal to apical portion. Eventually, some of the anatomical features of compression wood occurred at the primary growth. And the typical compression wood is gradually established during the secondary growth. On the other hand, the lower side tracheid and ray were longer and higher than those of the upper side in the horizontal first internode. However, difference in the width of ray was not observed between the lower and upper sides.

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ICR 마우스의 주요기관 형성기에 있어서 기형 발생의 시기특이성에 관한 실험적 검토 (Embryonic Effects of Radiation on ICR Mice Depending Developmental Stages)

  • 구연화;초간붕자;갑비윤명
    • 대한방사선기술학회지:방사선기술과학
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    • 제18권1호
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    • pp.91-95
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    • 1995
  • The ICR pregnant mice were irradiated at 1.5Gy in every 6 hours in the period of organogenesis in order to classify the stage specificity of the embryonic effects of radiation and the stage of development differentiation of the primordium of each major organ. Intrauterine death, fetal body weight and external malformation in live fetuses were observed on day 18 of gestation. There was no statistically significant difference in the intrauterine mortality at any stage organogenesis. The fetal body weight of the mice irradiated in the intermediate stage of organogenesis showed significantly lower. There were specific highly sensitive stages in the incidences of each external malformation, that is exencephalia, open eyelid, cleft palate, anomalies of extremities and anomalies of the tail. At these stage, the primordia of the major organs are established in ICR mice.

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아동의 초기 정서성, 양육행동 및 모자녀 애착과 남·여 아동의 행동억제간의 관계 (Behavioral Inhibition as a Function of Child's Early Emotionality, Parenting, and Mother-Child Attachment)

  • 박성은;박성연
    • 아동학회지
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    • 제22권2호
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    • pp.29-47
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    • 2001
  • In this study of 79 3- and 4-year-old children, behavioral inhibition was assessed by their preschool teachers; mother-child attachment was assessed by the researchers in home visits; and mothers reported on their parenting and their child's emotionality at 6-12 months of age. Findings were that insecure attachment was related to high child's distress reactions to limitations (negative emotionality) in early infancy and to strong maternal rejection/hostility. Higher maternal sensitivity to child's inhibition was related to more secure attachment. Girls were more highly inhibited than boys. Smiling and laughter (positive emotionality) in early infancy was negatively related to child's inhibited behavior. Maternal sensitivity to child inhibition was positively related to child's inhibited behavior. Findings are consistent with Engfer's (1993) theory of gender differences in developmental paths into behavioral inhibition.

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재조합유전자의 미세주입이 소 난포란의 체외발생에 미치는 영향 (The Effect of Pronuclear Injection of Recombinant DNA on the Development Potential of Bovine Follicular Oocytes In Vitro)

  • 이철상;한용만;박정선;강용국;김선정;유대열;이경광
    • 한국가축번식학회지
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    • 제17권3호
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    • pp.193-199
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    • 1993
  • Bovine follicular oocytes were matured in two different conditions, TCM 199+10% FBS with or without hormones (0.01 unit/ml ovine follicle stimulating hormone, 0.01 unit/ml ovine luteinizing hormone and 1$\mu\textrm{g}$/ml $\beta$-estradiol). There was no significant difference in maturation and fertilization rates of the oocytes between two groups. The result indicates that hormonal treatment does not have beneficial effect on in vitro maturation and fertilization of follicular oocytes. IVF-derived cone-cell bovine embryos were injected with foreign DNA (CChcLf) by microinjection method and then co-cultrued with bovine oviductal epithelial cells. Developmental rate of microinjected embryos to blastocyst stage (21%) was similar to that of non-injected embryos(29%). This result represents that microinjected bovine embryos produced in vitro have a potential of development to normal blastocysts.

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Streptomyces lavendulae의 균사체 발달에 따른 ascorbate oxidase 동위효소 양상 변화 (The change of ascorbate oxidase isozyme pattern during mycelial development of streptomyces lavendulae)

  • 이현무;김재헌
    • 미생물학회지
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    • 제26권2호
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    • pp.137-142
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    • 1988
  • pH decreased as the substrate mycelium developed, $\Delta$pH was 1.05-1.15, but increased after the aerial mycelium formation. The lactic acid content in culture solution showed no difference between 0.2% and 5% glucose, at which the aerial mycelium formation was repressed. The growth and development of mycelium was delayed by the lactate treatment. The activity of catalase was maximum in 24 hours after inoculation, and the wuperoxide dismutase activity showed a constant level during the developmental phases. The ascorbic acid accumulated after the aerial mycelium formation. The ascorbate oxidase isozyme of Rf 0.44 appeared, while the isozyme of Rf 0.36 desappeared during the development.

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아동과 청소년의 친구관계 발달에 관한 연구 (The Development of Friendships in Children and Adolescents)

  • 황혜정
    • 아동학회지
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    • 제23권3호
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    • pp.35-49
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    • 2002
  • This study examined the developmental characteristics of friends and disliked peers in 169 children and adolescents, including 44 preschool children, 43 primary school, 42 middle school, and 40 university students. Their descriptions of 2 same gender friends and 2 disliked same gender peers were categorized with an 81 category coding system. Comparisons across age and sex were made by a cross-tabulation test. Results showed that the reported characteristics of friends and disliked peers varied by age, but there was no sex difference. That is, younger children liked their friends because they played together, their friends were generous and attractive, but older children liked friends because they had some similarity, were reliable allies, caring and concerned. Younger children's disliked peers were aversive, aggressive and hyperactive while older children's disliked peers were dissimilar and snobbish.

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기혼자녀의 부모에 대한 애착 및 자율성 발달유형과 결혼만족도 (The Developmental Patterns of Attachment and Autonomy as Related to Young Adults' Marital Satisfaction)

  • 유은희
    • 대한가정학회지
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    • 제29권1호
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    • pp.139-158
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    • 1991
  • The purpose of this study is to investigate the relationship between adult children's perceived interaction pattern with their parents and their marital satisfaction. The subjects are a total of 646 male and female who been married for 3 years or less, living in Seoul, and whose fathers or mothers are still alive. The questionaire, including of attachment, autonomy, marital satisfaction scales, are distributed to collect the data. The main results are as follows: 1. Intimate-Dependent type is 31% each in relation to fathers and mothers. Distant-Independent type is 30% in relation to fathers, 27% in relation to mothers. Balanced type is 21% in relation to fathers, 23% in relation to mothers. Undeveloped type is 18% in relation to fathers, 19% in relation to mothers. 2. there is interaction effect between parental sex and adult children's sex as related to attachment levels, autonomy levels. 3. There is statistically significant difference among attachment-autonomy patterns as related to adult children's marital satisfaction. 4. Attachment and autonomy in relation to fathers and attachment in relation to mothers affect sons' marital satisfaction positively. Attachment in relation to fathers and mothers affect positively to daughters' marital satisfaction.

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Genetic Distances of Scallop (Chlamys farreri) Populations investigated by PCR Procedure

  • Yoon, Jong-Man
    • 한국발생생물학회지:발생과생식
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    • 제21권4호
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    • pp.435-440
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    • 2017
  • The author performed PCR-based genetic platform to measure the hierarchical dendrogram of Euclidean genetic distances of Korean scallop populations (KSP), particularly for Chlamys farreri, which was further compared with those of the Chinese scallop populations (CSP), by employing the with specifically designed oligonucleotide primer sets. The scallop is economically and ecologically very important bivalves in South Korea. Relatively, individuals of KSP population were fairly distantly related to that of CSP population, as shown in the hierarchical dendrogram of Euclidean genetic distances. Comparatively, individuals of KSP population were fairly distantly related to that of CSP population. Thus analysis of genetic difference between scallop populations could provide important statistics for fishery and aquaculture. Overall the results showed specific and/or conserved genetic loci between scallop populations. Information on the genetic distance of the bivalve would be helpful to understand scallop expansion or conservation in the coastal regions of South Korea. Specific markers developed by the author will be useful for the analysis of scallop population genetics and distribution in coastal region.