• 제목/요약/키워드: development rate

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한국형 고장률 데이터 북 개발에 대한 연구 (A Study on Development of Korean Failure Rate Databook)

  • 백순흠;임재학
    • 한국신뢰성학회지:신뢰성응용연구
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    • 제17권4호
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    • pp.305-315
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    • 2017
  • Purpose: The purpose of this research is to propose procedure and methodology for developing failure rate databook which is suitable for Korean operation environment. Methods: To this end, we investigate failure databooks used in foreign countries and study the procedure and methodology for collecting failure data, organizing the data, estimating failure rate and summarizing results. Results: We develop the procedure of development of failure databook, the items for data collection, database schema of part details and part summary and contents of failure databook by considering the application environment in Korea. Conclusion: The results of our research could be utilized for the development of Korean failure rate databook and research of reliability prediction model and could ultimately contribute to improve the accuracy of reliability prediction.

Effects of In Vitro Fertilization Conditions of In Vitro Matured Cumulus-Intact Pig Oocytes on Embryo Development

  • Kim, Jae-Young;Lee, Eun-Ji;Park, Jin-Mo;Lee, Hong-Cheol;Park, Hum-Dai;Kim, Jae-Myeong
    • 한국수정란이식학회지
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    • 제26권2호
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    • pp.117-122
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    • 2011
  • In this study, we examined the effectiveness of in vitro fertilization of porcine immature oocytes on the embryo development of blastocysts or hatched blastocysts and the number of cells according to the in vitro fertilization conditions. In the in vitro fertilization of in vitro matured porcine oocytes, there were no significant differences between treatment groups regarding fertilization rate, blastocyst rate, and embryo development of hatched blastocysts according to the storage periods of liquid sperm of 24, 48, and 72 hours. The embryo development rate of hatched blastocysts after the fertilization according to different spermatozoa concentrations ($0.4{\times}10^5$, $1.2{\times}10^5$, and $3.6{\times}10^5$ cells/ml) showed the highest rate in the group with a spermatozoa concentration of $1.2{\times}10^5$ cells/ml; in particular, this rate was significantly higher than that in the $0.4{\times}10^5$ cells/ml group (p<0.05). The total number of blastocysts cells as well as trophectoderms (TE) that developed in each treatment group were also significantly higher in the $1.2{\times}10^5$ cells/ml group than in any other groups (p<0.05). In contrast, the embryo development rate of blastocysts according to different co-incubation periods of sperm and oocyte (1, 3, and 6 hr) was high in the 6-hour group; in particular, the rate was significantly higher than that of the I-hour group (p<0.05). Furthermore, the total number of oocytes cells and TEs that developed was significantly higher in the 6-hour group than any other group (p<0.05). In this study, the most effective treatment conditions for porcine embryo development and high cell number were found to be as follows: a sperm storage period of less than 72 hours, a spermatozoa concentration of $1.2{\times}10^5$ cells/ml, and a 6-hour co-incubation period for sperm and ooocyte.

감귤 신품종(하양조생)개발의 기술가치의 평가 (A Study on the Technology Evaluation of Development of New Variety of Citrus Unshiu)

  • 고성보
    • 한국산학기술학회논문지
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    • 제17권8호
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    • pp.127-132
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    • 2016
  • 본 연구의 목적은 농촌진흥청 국립원예특작과학원 감귤시험장이 2014년 최종선발을 마친 감귤(학명:Citrus unshiu) 하양조생(제감가-5호) 품종개발의 기술가치를 평가하는 것이다. 감귤신품종(하양조생) 개발의 기술가치 및 경제적 평가방법은 비용접근법(cost approach), 수익접근법((income approach), 시장접근법(market approach) 중에 수익접근법이 이용되었고, 순현재가치(NPV), 내부수익률(IRR), 편익/비용 비율(Benefit/Cost ratio)을 추정하였다. 이는 농업 R&D사업의 효율성과 실용성 제고를 위하여 이용될 수 있을 것이다. 분석결과에 따르면, 감귤신품종인 하양조생 개발에 따른 기술가치평가액은 할인율 수준에 따라 최소 1,094.5억 원(할인율 8%)에서 최대 1,950.4억 원(할인율 4%), 평균 1,453.8억 원(할인율 6%)으로 추정되었고, 내부수익율 IRR의 값은 51.4%로 본 연구에서 기본할인율로 이용된 6%(10년만기 국고채 할인율 3%와 리스크프리미엄 3%를 합친 것) 보다 매우 크고, 순현재가치(NPV)의 평균은 145,375백만원으로 영보다 훨씬 크며, B/C 비율도 최대(할인율 4%) 81.3에서 최소(할인율 8%) 46.1, 평균(할인율 6%) 60.9로 나타나 감귤 신품종 개발사업의 경제적 타당성은 매우 높은 것으로 평가된다.

Effects of IGF-I and EGF Supplemented to PZM3 Culture Medium on the Development of Porcine Embryos In vitro

  • Kim, J.Y.;Park, M.C.;Kim, S.B.;Park, H.D.;Lee, J.H.;Kim, Jae-Myeoung
    • Asian-Australasian Journal of Animal Sciences
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    • 제22권8호
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    • pp.1117-1123
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    • 2009
  • This study investigated the effects of IGF-I and EGF on the development of blastocysts or hatched blastocysts during the in vitro culture of embryos from immature porcine oocytes. After the in vitro maturation and fertilization of cumulus-oocyte complexes (COCs) and their culture in vitro in PZM3 medium, we examined the embryo development rate for 168 h. When different concentrations of IGF-I (0, 1, 10, 20 ng/ml) were supplemented to fertilized porcine embryos in vitro, there were no significant differences in cleavage rate, blastocyst development rate or blastocyst hatching rate among the treated groups. On the other hand, when different concentrations of EGF (0, 1, 10, 20 ng/ml) were supplemented to the in vitro culture medium, blastocyst development rate was highest in the group in which EGF was not supplemented and, specifically, it was higher than in the 20 ng/ml treatment group (p<0.05). When 10 ng/ml IGF-I and 1 ng/ml EGF were supplemented separately or simultaneously, there were no significant differences among the treated groups in blastocyst hatching rate and the number of cells in each condition. This study demonstrated that the addition of IGF-I and EGF into PZM3 medium did not enhance development of the blastocyst stage and total cell number in blastocysts.

생쥐 2-세포기 수정란의 초급속동결 (Ultrarapid Freezing of Mouse 2-Cell Embryos)

  • 강만종;이철상;한용만;유대열;이경광
    • 한국가축번식학회지
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    • 제14권1호
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    • pp.9-16
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    • 1990
  • This study was carried out in order to investigate effects of cryoprotectant concentration and equilibration time on survival of ultrarapidly frozen 2-cell mouse embryos. Mouse 2-cell embryos, following dehydration by exposure to DMSO and sucrose, were directly immersed into liquid nitrogen and thawed in 37$^{\circ}C$ water. Viability was defined by development rate to the blastocyst stage after in vitro culture for 72 hours. The results are summarized as follows ; 1. When 0.25M of sucrose was added into the freezing medium at various concentrations of DMSO and dilution medium, higher development rate of embryo was obtained in 3.0M DMSO concentrations (82.6%). However, when sucrose concentraitons of 0.25 and 0.5 M were added to the freezing medium with 3.0 M DMSO and dilution medium, development rate of embryos were 81.7% and 24.1%, respectively. 2. In the equilibration time at room temperature, higher development rate was attained after short period of time (2.5min) in 3.0 M DMSO+0.25 M sucrose (85.9%). 3. The development rate of embryos at in vitro 2-cell, in vitro 2-cell, solution control and untreated control was 84.6%, 90.9%, 89.9%,, and 89.7%, respectively.

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특정(特定) 전염성(傳染性) 병인체(病因體)에 대한 국내(國內) 종계(種鷄)의 항체(抗體) 보유상황(保有狀況) (Prevalence of Serum Antibodies in Breeder Chickens against Specific Avian Pathogens)

  • 김순재;이영옥;김선중;전우상;박근식
    • 대한수의학회지
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    • 제20권1호
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    • pp.59-64
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    • 1980
  • Incidence of avian infectious diseases in breeder chickens was followed serologically. Serum samples were collected during the period of 1978~1979 from breeders throughout country and tested for the presence of antibodies against Salmonella pullorum(SP), Mycoplasma gallisepticum(MG), Avian Infectious Bronchitis virus(AIBV), Infectious Bursal Disease virus(IBDV) and Egg Drop Syndrome Virus(EDS). The tests used serum plate agglutination for SP and MG, immuno-diffusion for AIBV and IBDV and hemagglutination-inhibition test for EDS virus. The results are summarized as follows: 1. Individuals and Hocks incidence rate of Avian Infectious Bronchitis virus were 16.9% and 55.3%. 2. Individuals and Hocks incidence rate of Infectious Bursal Disease virus were 50.1% and 66.4%. 3. Individuals and Hocks incidence rate of sal. pullorum were 17.2% and 65.9%. 4. Individuals and flocks incidence rate of M. gallisepticum were 36.2% and 63.2%. 5. Individuals and flocks incidence rate of Egg Drop Syndrome (BC 14) virus were 14.1% and 46.3%.

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Effects of 8-Week Elastic Resistance Exercise on Knee Isokinetic Rate of Velocity Development and Balance by Age

  • Youngmin Choi;Kihong Kim;Hwanjong Jeong
    • International journal of advanced smart convergence
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    • 제12권4호
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    • pp.395-406
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    • 2023
  • Ten women in their 20s and 10 women in their 50s were selected to investigate the effect of an elastic band exercise program for 8 weeks according to age on women's knee speed expression rate and balance. Knee isokinetic muscle strength measurement, single-legged standing with eyes closed, and YBT were performed 1 week before and after the exercise program. The measured data were analyzed through a mixed design two-way ANOVA, and if there was a significant difference, post hoc verification was performed using the bonferoni method. In our study, as a result of an 8-week elastic band exercise program, there was no difference in the speed development rate according to the measurement period, and the speed development rate according to age was found to be higher in people in their 50s than in their 20s. In our study, there was no difference in balance ability depending on the measurement period, and there was also no difference in balance ability depending on age. Discussing the results of our study, we found that 8 weeks of elastic band exercise cannot bring about significant changes in speed development ability and balance ability, which become more accurate with age.

Investigation of rate dependent shear bond properties of concrete masonry mortar joints under high-rate loading

  • John E. Hatfield;Genevieve L. Pezzola;John M. Hoemann;James S. Davidson
    • Computers and Concrete
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    • 제33권5호
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    • pp.519-533
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    • 2024
  • Many materials including cementitious concrete-type materials undergo material property changes during high-rate loading. There is a wealth of research regarding this phenomenon for concrete in compression and tension. However, there is minimal knowledge about how mortar material used in concrete masonry unit (CMU) construction behaves in high-rate shear loading. A series of experiments was conducted to examine the bond strength of mortar bonded to CMU units under high-rate shear loading. A novel experimental setup using a shock tube and dynamic ram were used to load specially constructed shear triplets in a double lap shear configuration with no pre-compression. The Finite Element Method was leveraged in conjunction with data from the experimental investigation to establish if the shear bond between concrete masonry units and mortar exhibits any rate dependency. An increase in shear bond strength was observed when loaded at a high strain rate. This data indicates that the CMU-mortar bond exhibits a rate dependent strength change and illustrates the need for further study of the CMU-mortar interface characteristics at high strain rates.

Sensing Domain and Extension Rate of a Family B-Type DNA Polymerase Determine the Stalling at a Deaminated Base

  • Kim, Yun-Jae;Cha, Sun-Shin;Lee, Hyun-Sook;Ryu, Yong-Gu;Bae, Seung-Seob;Cho, Yo-Na;Cho, Hyun-Soo;Kim, Sang-Jin;Kwon, Suk-Tae;Lee, Jung-Hyun;Kang, Sung-Gyun
    • Journal of Microbiology and Biotechnology
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    • 제18권8호
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    • pp.1377-1385
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    • 2008
  • The uracil-sensing domain in archaeal family B-type DNA polymerases recognizes pro-mutagenic uracils in the DNA template, leading to stalling of DNA polymerases. Here, we describe our new findings regarding the molecular, mechanism underpinning the stalling of polymerases. We observed that two successive deaminated bases were required to stall TNA1 and KOD1 DNA polymerases, whereas a single deaminated base was enough for stalling Pfu DNA polymerase, in spite of the virtually identical uracil-sensing domains. TNA1 and KOD1 DNA polymerases have a much higher extension rate than Pfu DNA polymerase; decreasing the extension rate resulted in stalling by TNA1 and KOD1 DNA polymerases at a single deaminated base. These results strongly suggest that these polymerases require two factors to stop DNA polymerization at a single deaminated base: the presence of the uracil-sensing domain and a relatively slow extension rate.

Synnemata Production Using Silkworm Variety, Female Yangwonjam by Isaria tenuipes

  • Ji, Sang-Duk;Sung, Gyoo-Byung;Kang, Pil-Don;Kim, Kee-Young;Choi, Yong-Soo;Kim, Nam-Suk;Woo, Soon-Ok;Han, Sang-Mi;Hong, In-Pyo;Ha, Nam-Gyu
    • Mycobiology
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    • 제39권3호
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    • pp.158-163
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    • 2011
  • This study was conducted to confirm the possible use of female Yangwonjam as a host for synnemata production of Isaria tenuipes in eight local areas in Korea. Silkworm pupation rate, infection rate and synnemata characteristics of I. tenuipes were examined. Normal silkworms had a higher pupation rate than silkworms inoculated with I. tenuipes. The pupae survival percentage of normal silkworm in cocoons was 92.5~97.6%, whereas it ranged from 91.1~95.6% in silkworms sprayed with I. tenuipes. Female Yangwonjam showed the highest survival percentage at 97.6% among the silkworm varieties tested. I. tenuipes infection rate of larvae of 5th instar newly-exuviated silkworms was 89.2~90.7% in the spring rearing season and 98.2~99.3% in the autumn rearing season. Synnemata production of I. tenuipes was excellent in female Yangwonjam with an incidence rate of 98.0% followed by male Yangwonjam (94.1%) and Baegokjam (93.3%) in the spring rearing season. Synnemata living weight ranged from 1.44~0.94 g in the spring rearing season. The female Yangwonjam had the heaviest synnemata weight (1.44 g) in the spring rearing season. The synnemata of I. tenuipes produced on pupae were white or milky-white in color, and were similar in shape and color to wild synnemata collected in Korea.