• Bulletin of the Korean Chemical Society
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• 제34권11호
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• pp.3199-3205
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• 2013

The inclusion behavior of sulfobutylether-${\beta}$-cyclodextrin (SBE-${\beta}$-CD) with perphenazine (PPH) was first studied by flow injection (FI)-chemiluminescence (CL) analysis with proposed $lg[(I_0-I_s)/I_s]=lgK_{P-CD}+nlg[C_{PPH}]$ model and molecular docking. Results showed that a 1:1 complex of SBE-${\beta}$-CD/PPH could online form, with the formation constant $K_{P-CD}$ of $2.57{\times}10^7Lmol^{-1}$ at 298 K. The thermodynamic parameters showed that the inclusion behavior of SBE-${\beta}$-CD/PPH was a spontaneous process by hydrophobic interaction. The molecular docking results revealed PPH entered into the larger cavity of SBE-${\beta}$-CD with two hydrogen bonds. Based on the linear relationship of the decrement of luminol/SBE-${\beta}$-CD/PPH CL intensity against the logarithm of PPH concentration ranging from 0.03 to 30.0 ng $mL^{-1}$, the present FI-CL analysis using luminol/SBE-${\beta}$-CD/PPH system was successfully applied to PPH determination in biological fluids and tablets with recoveries from 94.5 to 105.6% and RSDs less than 2.6% (n = 5).

• 한국농공학회지
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• 제44권7호
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• pp.64-73
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• 2002

This study was performed to evaluate effects of physical characteristics of both watershed and reservoir on nutrient-chlorophyll relationship in Korean reservoirs. Simple linear models were developed with published data in Korea including 415 reservoirs and 11 multi-purpose dams, and physico-chemical parameters of reservoirs and characteristics relationship of models were analyzed. Theoretical residence time in Korean reservoirs was strongly correlated with the ratio of TA/ST (drainage area + surface area / storage volume) in the logarithmic function. As a result of monthly nutrients-chlorophyll-a regression analysis, significant Chl-a-TP relationship appeared during May～July. The high Chl-a yields per total phosphorus appeared during this time (R$\^$2/=0.51, p<0.001, N= 1088). Chlorophyll-a demonstrated much stronger relationship with TP. than TN. Seasonal algal-nutrient coupling were closely related with N:P ratio in the reservoir water, and it was, in turn, dependent on the monsoon climatic condition (precipitation). Based on the results of regression analysis and high N:P ratio, a major limiting factor of algal growth appeared to be phosphorus during this time. Unlikely TA/ST ratio, DA/SA ratio (drainage area f surface area) was likely to influence directly on the nutrient-Chl-a relationship, indicating that if storage volume and inflowing water volume were the same, algal biomass could be developed more in reservoirs with large surface area. Thus, DA/SA ratio seemed to be an important factor to affect the development of algal biomass in Korean reservoirs. With low determination coefficient of TP-Chl-a relationship, our findings indicated not only nutrient (phosphorus) but also other physical factors, such as DA/SA ratio, may affect algal biomass development in Korean reservoirs, where actual residence time appears to be more closely related to reservoir surface area rather than storage volume.

• Computers and Concrete
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• 제19권6호
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• pp.711-716
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• 2017

This paper presents a method using artificial neural networks (ANNs) to predict the residual moment capacity of thermally insulated reinforced concrete (RC) beams exposed to fire. The use of heat resistant insulation material protects concrete beams against the harmful effects of fire. If it is desired to calculate the residual moment capacity of the beams in this state, the determination of the moment capacity of thermally insulated beams exposed to fire involves several consecutive calculations, which is significantly easier when ANNs are used. Beam width, beam effective depth, fire duration, concrete compressive and steel tensile strength, steel area, thermal conductivity of insulation material can influence behavior of RC beams exposed to high temperatures. In this study, a finite difference method was used to calculate the temperature distribution in a cross section of the beam, and temperature distribution, reduction mechanical properties of concrete and reinforcing steel and moment capacity were calculated using existing relations in literature. Data was generated for 336 beams with different beam width ($b_w$), beam account height (h), fire duration (t), mechanical properties of concrete ($f_{cd}$) and reinforcing steel ($f_{yd}$), steel area ($A_s$), insulation material thermal conductivity (kinsulation). Five input parameters ($b_w$, h, $f_{cd}$, $f_{yd}$, $A_s$ and $k_{insulation}$) were used in the ANN to estimate the moment capacity ($M_r$). The trained model allowed the investigation of the effects on the moment capacity of the insulation material and the results indicated that the use of insulation materials with the smallest value of the thermal conductivities used in calculations is effective in protecting the RC beam against fire.

• Journal of Biosystems Engineering
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• 제39권3호
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• pp.244-252
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• 2014

Purpose: The development of an efficient in vitro cell culture device to process various cells would represent a major milestone in biological science and engineering. However, the current conventional macro-scale in vitro cell culture platforms are limited in their capacity for detailed analysis and determination of cellular behavior in complex environments. This paper describes a microfluidic-based culture device that allows accurate control of parameters of physical cues such as pressure. Methods: A microfluidic device, as a model microbioreactor, was designed and fabricated to culture Saccharomyces cerevisiae and Chlamydomonas reinhardtii under various conditions of physical pressure stimulus. This device was compatible with live-cell imaging and allowed quantitative analysis of physical cue-induced behavior in yeast and microalgae. Results: A simple microfluidic-based in vitro cell culture device containing a cell culture channel and an air channel was developed to investigate physical pressure stress-induced behavior in yeasts and microalgae. The shapes of Saccharomyces cerevisiae and Chlamydomonas reinhardtii could be controlled under compressive stress. The lipid production by Chlamydomonas reinhardtii was significantly enhanced by compressive stress in the microfluidic device when compared to cells cultured without compressive stress. Conclusions: This microfluidic-based in vitro cell culture device can be used as a tool for quantitative analysis of cellular behavior under complex physical and chemical conditions.

• 한국지구과학회지
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• 제30권7호
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• pp.810-823
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• 2009

지진원 상수의 정밀한 결정과 지진재해의 예측에 있어서 결정적인 요인의 하나는 부지증폭 특성에 관한 상세한 정보이다. 한반도 광대역 지진관측소의 부지증폭 특성이 0.2-20 Hz 범위 내에서 주파수의 함수로 추정되었다. 한반도 남부에서 2003년부터 2008년까지 관측된 43개의 지진에 대한 총 1275개의 지진기록이 사용되었다. 지진동 모델의 역산으로부터 추정된 28개소의 관측소에 대한 부지증폭비는 수직대 수평(H/V) 스펙트럼비로부터 얻어진 증폭비와 몇몇 관측소를 제외하고는 대체로 그 값이 일치하는 것이 발견되었다. 이 연구에서 얻어진 주파수별 부지증폭 특성은 어떤 뚜렷한 공간분포를 보이지 않았다. 또한 부지증폭 특성은 기반암 종류보다는 풍화의 정도와 크게 관련이 있는 것으로 나타났다. 주파수별 부지증폭비를 참조하여 28개소의 광대역 관측소를 4개의 그룹으로 나누었고, 그룹별 특징에 대하여 본문에 서술하였다.

• Wind and Structures
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• 제26권3호
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• pp.129-146
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• 2018

Extreme wind speed analysis has been carried out conventionally by assuming the extreme series data is stationary. However, time-varying trends of the extreme wind speed series could be detected at many surface meteorological stations in China. Two main reasons, exposure change and climate change, were provided to explain the temporal trends of daily maximum wind speed and annual maximum wind speed series data, recorded at Hangzhou (China) meteorological station. After making a correction on wind speed series for time varying exposure, it is necessary to perform non-stationary statistical modeling on the corrected extreme wind speed data series in addition to the classical extreme value analysis. The generalized extreme value (GEV) distribution with time-dependent location and scale parameters was selected as a non-stationary model to describe the corrected extreme wind speed series. The obtained non-stationary extreme value models were then used to estimate the non-stationary extreme wind speed quantiles with various mean recurrence intervals (MRIs) considering changing climate, and compared to the corresponding stationary ones with various MRIs for the Hangzhou area in China. The results indicate that the non-stationary property or dependence of extreme wind speed data should be carefully evaluated and reflected in the determination of design wind speeds.

• 사물인터넷융복합논문지
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• 제6권3호
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• pp.59-65
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• 2020

일상에서 이용하는 모든 물건들이 네트워크 접속 기능을 갖추고, 이들이 긴밀하게 연동하면서 생활 및 업무의 편의성을 높이는 IoT(사물인터넷) 시대가 활짝 열렸다. 로봇도 IoT 환경에 맞춰 발전해야 하는 상황이다. 논문에서는 IoT 환경을 위한 다리가 있는 로봇 궤적을 생성하기 위해 새로운 형태의 EFM (진화 퍼지 머신)을 사용하는 방법에 대하여 다룬다. 퍼지 시스템은 비선형 시스템을 묘사하는 데 널리 사용되고 있다. 퍼지 시스템에서 퍼지 모델의 전반부 및 후반부 구조를 결정하는 것은 매우 중요한 문제이다. EFM은 다리가 달린 로봇을 위해 퍼지 시스템의 전반부 및 후반부 구조를 진화시켜 효율적으로 구조를 개선한다. 퍼지 시스템에서 각 구조의 로봇 궤적 매개 변수를 생성하고 EFM에 의해 자동으로 조정된다. 제안된 접근 방식은 다리가 있는 로봇에 적용하여 성능을 살펴본다.

• Smart Structures and Systems
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• 제11권4호
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• pp.411-433
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• 2013

Due to its easy operation and wide applicability, the ambient vibration method is commonly adopted to determine the cable force by first identifying the cable frequencies from the vibration signals. With given vibration length and flexural rigidity, an analytical or empirical formula is then used with these cable frequencies to calculate the cable force. It is, however, usually difficult to decide the two required parameters, especially the vibration length due to uncertain boundary constraints. To tackle this problem, a new concept of combining the modal frequencies and mode shape ratios is fully explored in this study for developing an accurate method merely based on ambient vibration measurements. A simply supported beam model with an axial tension is adopted and the effective vibration length of cable is then independently determined based on the mode shape ratios identified from the synchronized measurements. With the effective vibration length obtained and the identified modal frequencies, the cable force and flexural rigidity can then be solved using simple linear regression techniques. The feasibility and accuracy of the proposed method is extensively verified with demonstrative numerical examples and actual applications to different cable-stayed bridges. Furthermore, several important issues in engineering practice such as the number of sensors and selection of modes are also thoroughly investigated.

• 한국측량학회지
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• 제17권1호
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• pp.21-32
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• 1999

항공사진측량에 의한 지도제작과 미지점의 정확한 위치결정은 매우 경제적인 방법이나 외부표정요소를 구하기 위해서는 기준점이 필요하다. 번들조정기법의 성능향상과 횡스트립의 설치로 블럭조정에 요구되어지는 기준점의수가 감소되었음에도 불구하고 기준점 측량은 비용면에서 무시할 수 없는 부분이다. 이러한 단점을 보완하기 위해 연구된 동적 DGPS-위치결정에 의한 GPS-항측은 처음 가능성을 보인 이래 계속 발전되어 오고 있다. 위성배치의 완료, 수신기의 기능 향상 및 동적 DGPS-위치결정을 위한 S/W의 향상 등으로 결합블럭조정의 정확도도 크게 증가하고 있다. 따라서 GPS-항측의 실용화에 대한 연구가 보다 절실히 요청되고 있는 실정이다. 본 연구의 대상지는 60%의 횡중복도와 횡스트립으로 촬영하여 광산지역의 지반침하를 조사하기 위하여 실시되었다. 단지 6개의 기준점만을 사용한 결합블럭조정으로도 21개의 수평기준점과 81개의 연직기준점을 사용한 재래식 블럭조정과 같은 결과를 얻을 수 있었다. 또한 GPS에 의한 노출점의 위치와 블록조정의 정확도는 지상 수신기준점의 거리와는 무관하였으며 결합블럭조정시 정오차 소거를 위한 특별한 모형식이 필요함을 알 수 있었다.

• 한국광학회지
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• 제14권1호
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• pp.1-7
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• 2003

유기발광물질 Alq$_3$ 복소굴절률을 양자역학적 흡수이론인 바탕인 포로히-블루머(Forouhi-Bloomer) 분산식[Phys. Rev. B 34. 7018(1986)]을 이용하여 1.5~6 ev의 영역에서 계산하였다. 분광광도계를 이용하여 측정한 Alq$_3$ 박막의 흡수 스펙트럼에서 흡수 피크의 위치와 폭으로부터 포로히-블루머 분산식의 변수 $A_{i}$ , B$_{i}$, $C_{i}$ 의 초기 근사값을 결정하였다. 기판으로 사용한 비정질실리카(fused silica)의 굴절률은 분광광도계로부터 측정된 투과율과 반사율 스펙트럼으로부터 셀마이어(Sellmeier)분산식을 적용하여 계산하였다. 기판의 굴절률과 분광광토계에서 측정한 Alq$_3$박막의 투과율과 반사율 스펙트럼에 포로히-블루머 분산식을 이용한 비선형 최소자승법 곡선맞춤을 하여 Alq$_3$의 복소굴절률을 계산할 수 있었다.