• 한국지역사회생활과학회지
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• 제14권3호
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• pp.59-65
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• 2003

This study was carried out to investigate the supplementary effects of the rice germ oil compared with soy bean oil on lipid metabolism of non-insulin dependent diabetic mice. Forty diabetic KK mice were fed two kinds of experimental diets with 20% lipid from soy bean oil as a control(CO) and rice germ oil(RG) for 8 weeks, respectively. Diet intake, body weight, organs weights and lipids levels of serum, liver and feces were measured. There was no significant difference in food and water intake, body weight gain and organs weights between experimental groups. But the concentrations of serum total cholesterol and LDL-cholesterol were lower in RG group than in CO group. The hepatic total lipid and total cholesterol levels of RG group were significantly lower than those of CO group. The contents of total lipid, triglyceride and total cholesterol excreted in feces of RG group were higher than those of CO group. These results suggested that rice germ oil can reduce serum total cholesterol and LDL-cholesterol and hepatic total lipid concentration of non-insulin dependent diabetic mice compared with soybean oil due to increasing fecal lipid excretion. But we need to investigate the hypolipidemic effect of this oil by supplementary level and period.

• 지역사회간호학회지
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• 제17권4호
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• pp.552-562
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• 2006

Purpose: This study was conducted to describe the state of middle school students' addicted use of a cellular phone and their psychosocial characteristics and to examine differences in psychosocial factors as impulsivity, stress, anxiety and classroom attitudes according to the level of addiction. Method: As the subjects of this study, 747 middle school students who use a cellular phone in B Metropolitan City were selected through stratified random sampling, and they were asked to answer a self-administered study questionnaire. Data were analyzed using frequency, descriptive statistics, $x^2-test$, t-test, and one-way ANOVA. Results Among the respondents, 15.7% fell into the addicted user group while 56.0% fell into the dependent user group and 28.3% turned out to be non-addicted users. The levels of impulsivity, stress and anxiety were higher in the addicted user group than in the dependent user group and the non-addicted user group. The addicted user group also showed a very bad learning attitude. Conclusion: Addiction to the use of a cellular phone, which may have negative influences on the users' psychosocial characteristics, needs to be detected earlier, and preventive education should be offered in order to prevent such addiction.

• 대한한의학방제학회지
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• 제12권1호
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• pp.195-208
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• 2004

Objective: This study was conducted to investigate the effects of Aconiti Tuber on the plasma IL-6 and $TNF-{\alpha}$ level in mice stimulated by intracerebroventricular(I.C.V.) Injection of Lipopolysaccharide(LPS). Method: 6 mice were assigned to each of the normal group, the control group, and the experimental group. In the normal group only saline was administered intragastrically, and in the control group LPS was injected intracerebro-ventricularly 1 hr after intragastric administration of saline. In the experimental groups (Aconiti Tuber 0.5g/kg, Aconiti Tuber 1.0g/kg, Aconiti Tuber 3.0g/kg) each sample was administered intragastrically to mice 1 hr prior to the stimulation by LPS I.C.V. Injection. To measure the plasma IL-6 and $TNF-{\alpha}$ level of mice, their blood samples were collected from retro-orbital plexus, immediately centrifuged at $4^{\circ}C$, and plasma was removed and stored frozen at $-83^{\circ}C$ for later determination of plasma IL-6 and $TNF-{\alpha}$. Result : 1. LPS I.C.V. Injection increased plasma IL-6 level significantly in a dose-dependent manner compared with normal group(P<0.01). The plasma IL-6 concentration reached a significant maximal level about 1 hr after LPS I.C.V. Injection(P<0.001). LPS I.C.V. Injection increased plasma $TNF-{\alpha}$ level significantly in a dose-dependent manner(P<0.05). The plasma $TNF-{\alpha}$ concentration reached a significant maximal level about 1 hr after LPS I.C.V. Injection(P<0.001). 2. Sample A group to which Aconiti Tuber(0.5g/kg) was administered intragastrically 1 hr prior to the stimulation by LPS I.C.V. Injection showed insignificant lower plasma IL-6 level in 1 hr than control group(P<0.0635), and sample B group (Aconiti Tuber 1.0g/kg) showed significant lower plasma IL-6 level in 1 hr than control group(P〈0.05), and sample C group (Aconiti Tuber 3.0g/kg) showed significant lower IL-6 plasma level in 1 hr than control group(P<0.01). 3. sample A group to which Aconiti Tuber(0.5g/kg) was administered intragastrically 1 hr prior to the stimulation by LPS I.C.V. Injection showed insignificant lower plasma $TNF-{\alpha}$ level in 1 hr than control group(P>0.05), and Both sample B(1.0g/kg) and sample C(3.0g/kg) groups showed significant lower $TNF-{\alpha}$ plasma level in 1 hr than control group(P<0.01). These data revealed that Aconiti Tuber might have the anti inflammatory effect by reducing the plasma IL-6 and $TNF-{\alpha}$ level in a dose dependent manner in mice LPS I.C.V. Injection.

• International Journal of Naval Architecture and Ocean Engineering
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• 제12권1호
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• pp.657-666
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• 2020

A reliable and cost-effective technique for the development of corrosion damage model is introduced to predict nonlinear time-dependent corrosion wastage of steel structures. A detailed explanation on how to propose a generalised mathematical formulation of the corrosion model is investigated in this paper (Part I), and verification and application of the developed method are covered in the following paper (Part II) by adopting corrosion data of a ship's ballast tank structure. In this study, probabilistic approaches including statistical analysis were applied to select the best fit probability density function (PDF) for the measured corrosion data. The sub-parameters of selected PDF, e.g., the largest extreme value distribution consisting of scale, and shape parameters, can be formulated as a function of time using curve fitting method. The proposed technique to formulate the refined time-dependent corrosion wastage model (TDCWM) will be useful for engineers as it provides an easy and accurate prediction of the 1) starting time of corrosion, 2) remaining life of the structure, and 3) nonlinear corrosion damage amount over time. In addition, the obtained outcome can be utilised for the development of simplified engineering software shown in Appendix B.

• 대한한의학회지
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• 제25권4호
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• pp.200-208
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• 2004

Objective: Non-insulin Dependent Diabetes Mellitus (NIDDM) is characterized by insulin resistance, which affects the glucose transportation inside the cell. The purpose of this study was to find out how Palmijihwangtang (PMT) and exercise influence the glucose transport metabolism in the organ muscles of ZDF (zucker diabetic fatty) rat with insulin resistance. Methods: Using three male normal zucker rats and twelve male obese rats, they were divided into a normal lean group (N=3), obese control group (N=3), obese exercises group (N=3), obese medication group (N=3), obese exercise and medication group (N=3). Treadmill exercise were repeated with 27m/min speed for an hour a day, five days a week, for 8 weeks. And 20β/sub ￠/ of PMT was orally administered twice a day for 8 weeks, after that a period blood sample was exsanguinated by heart perforation and was analyzed. Results: The body weight of the OM and OEM group showed a significant decrease among all the obese groups. The blood insulin level increased significantly of all groups in comparison with the N group. All of the OE, OM and the OEM groups showed a significant decrease of insulin level compared with the OC group; especially the OEM group demonstrated the most among obese groups. Regarding GLUT-4 level, OEM was the unique group showed a significant increase among all the obese groups. The VAMP-2 level in myocardium cell membrane was increased significantly at OC group in comparison with the N group, whereas the OEM group only showed significant decrease of it. In addition, the VAMP-2 level in pancreas β-cell was significantly decreased at all the obese groups in comparison with the N group. Only the OEM group showed significant increase among all the obese groups. Conclusion: Palmijihwangtang (PMT) and exercise could effectively promote the insulin metabolism in pancreas β-cells and activate the glucose transport process in myocardium cell membrane by lowering the insulin resistance of ZDF rats.

• Child Health Nursing Research
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• 제7권2호
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• pp.213-224
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• 2001

This study was conducted to identify the effect on the weight control of the REBT group program as a nursing intervention. For this purpose, non-equivalent control group design with pretest and posttest and follow-up test as quasi-experiment was used. Subjects of the study were consisted of twenty-four obese girls (Experimental group: 10, control group: 14) who appeared to having above 20％ of the body mass index from ane high school in M city. The whole program was carried out from January to June, 2000. Used dependent variables for evaluating the effect of the REBT group program including were weight control belief(rational thinking, emotion about exercise, eating self-efficacy, eating behavior), body mass index and serum lipids(total cholesterol, triglyceride, low-density lipoprotein, high-density lipoprotein). For evaluating the effect of the program, dependent variables was analyzed by experimental stages three times; the first week, the fourth week, and the eighth week since the experimental input began. Data were analyzed by the SAS PC＋ program with t-test, repeated measure ANOVA to determine the effect of program. The results of this study can be summarized as follows; 1. After the REBT group program, only eating self-efficacy among the weight control belief of experimental group was significantly increased than that of control group. 2. After the REBT group program, body mass index of experiment group was significantly decreased than that of control group. 3. After the REBT group program, triglyceride and low density lipoprotein among the serum lipids in the experiment group were significantly decreased than those of control group.

• 대한산업공학회지
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• 제11권2호
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• pp.75-85
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• 1985

The application of GT results in the mass production effect to multi-product, small lot-sized production. Group scheduling, which is operations scheduling based on the GT concept, is analyzed in a multistage manufacturing system. But the research has been limited in independent setup time models. A heuristic algorithm has been developed to minimize the mean flow time when setup times are dependent to sequence of group in multistage. For evaluation of the heuristic algorithm, the solution of heuristic algorithm is compared with that of random scheduling. The result of comparison indicates that the proposed heuristic algorithm provides good solutions with relatively fewer computational effort.

• The Journal of the Acoustical Society of Korea
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• 제15권2E호
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• pp.14-23
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• 1996

This paper is a on the neural network to recognize the phonemes, the weight initialization to reduce learning speed, and LR parser for continuous speech recognition. The neural network spots the phonemes in continuous speech and LR parser parses the output of neural network. The whole phonemes recognized in neural network are divided into several groups which are grouped by the similarity of phonemes, and then each group consists of neural network. Each group of neural network to recognize the phonemes consisits of that recognize the phonemes of their own group and VGNN(Verify Group Neural Network) which judges whether the inputs are their own group or not. The weights of neural network are not initialized with random values but initialized from learning data to reduce learning speed. The LR parsing method applied to this paper is not a method which traces a unique path, but one which traces several possible paths because the output of neural network is not accurate. The parser processes the continuous speech frame by frame as accumulating the output of neural network through several possible paths. If this accumulated path-value drops below the threshold value, this path is deleted in possible parsing paths. This paper applies the continuous speech recognition system to the threshold value, this path is deleted in possible parsing paths. This paper applies the continuous speech recognition system to the continuous Korea digits recognition. The recognition rate of isolated digits is 97% in speaker dependent, and 75% in speaker dependent. The recognition rate of continuous digits is 74% in spaker dependent.

• 한국지역사회생활과학회지
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• 제14권2호
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• pp.83-92
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• 2003

This study was carried out to investigate the supplementary effects of soybean oil and rice gem oil compared with lard on lipid metabolism of insulin dependent diabetic mice. Streptozotocin-induced diabetic mice were fed three kinds of experimental diets with 20% lipid from lard(L), soy bean oil(SBO) and rice gem oil(RGO) for 7 weeks, respectively. Diet intake, body weight, organs weights and lipids levels of serum, liver and feces were measured. There was no significant difference in diet intake, body and organs weights among experimental groups. But the concentrations of serum triglyceride of SBO and RGO groups, and of serum total cholesterol were lower in RGO group than in the other groups. The hepatic total lipid and total cholesterol levels of RGO group were significantly lower than those of the other groups. The contents of total lipid and total cholesterol excreted in feces of SBO and RGO groups were higher than those of L group, and the significance was shown only in RGO group. These results suggested that soy bean oil and rice germ oil can reduce serum triglyceride and total cholesterol levels and hepatic total lipid concentration of insulin dependent diabetic mice compared with lard as a animal fat source by increasing fecal lipid excretion of these groups. But the significant reducing effects on serum and liver lipid levels were shown only in RGO group, and we need to investigate the hypolipidemic effect of this oil by supplementary level and period.

• Archives of Pharmacal Research
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• 제19권5호
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• pp.390-395
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• 1996

To investigate whether $AT_{1}$ receptor antagonists are acting by increasing endothelium-de-pendent and -independent relaxation of aortas in normotensive rats, $AT_{1}$ receptor antagonists, losartan and KR-30988, and angiotensin converting enzyme inhibitor, captopril, were orally administered for two weeks (50 mg/kg, b.i.d.). THe blood pressure, heart rate and body weight were not significantly changed by losartan, KR-30988 and captopril compared to the control group. In aortic preparations, the $pD_{2}$ of KR-30988 for ACh-induced relaxation was 8.33 $\pm$ 0.16, significantly (p <0.05) lower than that of control group $(7.71 \pm 0.15)$. ACh-induced relaxation was significantly increased on losartan-treated group (p<0.01) at $10^{-6}$ M of ACh, and in captopril-treated group (p<0.05) at the range of $10^{-7}$ -$10^{-5}$ M of ACh. The $pD_{2}$ values for histamine-induced relaxatio of losartan, KR-30988 and captopril were 5.57 $\pm$ 0.10, 5.85 $\pm$ 0.21 and 5.60 $\pm$ 0.01, respectively, with significant differences in all groups (p<0.01) compared to that of control group (5.13 $\pm$ 0.09). ACh-induced relaxations of aortic preparations were not changed by pretreatment of indomethacin ($10_{-5}$ M), and completely bolcked by pretreatment of L-NAME $(10_{-5}M)$ in all groups. Sodium nitroprusside-induced relaxations were not significantly changed by all drugs tested in this experiments. These results suggest that $AT_{1}$ receptor antagonists, losartan and KR-30988, enhance the endothelium-dependent relaxatio on aortic preparations through the release of, or increase sensitivity, to nitric oxide in nor-motensive rats.