• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 춘계학술대회
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• pp.1678-1681
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• 2004

The light-transmission technique has been applied to a slit rheometer for measuring red blood cell aggregation as well as blood viscosity over a range of shear rates. For measurement of blood viscosity and aggregation, instantaneous pressure and transmit-light intensity are measured with time. Using a precision pressure measurement, one can determine the shear stress and shear rate. In addition, a transmitted light through a blood sample indicates degree of RBC aggregation. With abruptly flowing with high shear rate, RBCs rapidly disaggregate and the intensity of the transmitted light becomes low. When continuously flowing with decreasing shear rate, RBCs tend to re-aggregate and the corresponding transmit-intensity gradually increases with time. The light intensity as a degree of RBC aggregation is plotted against shear rate and compared with blood viscosity. The advantages of this design are dual measurement at a time, simplicity, i.e., ease of operation and no moving parts, low cost, short operating time, and the disposable kit which is contacted with blood sample.

• Journal of Information Technology Applications and Management
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• 제9권1호
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• pp.127-142
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• 2002

This study examines various factors which influence the degree of Participation In B to B e-Marketplace. Based on literature review, six factors such as Information provision, IT infrastructure, trust, aggregation, new customer creation, and matching are identified. To collect the empirical data, survey methodology has been utilized. A total of 32 companies have returned completed responses. The results of analysis show high interdependencies between six factors and the degree of participation in e-Marketplace. In particular, aggregation is found to be the most influential factor. Additional analysis reveals that firms participating highly in e-Marketplace recognize aggregation and new customer creation the most important factors while less participating firms see IT infrastructure more important.

• Journal of Nutrition and Health
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• 제32권5호
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• pp.561-569
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• 1999

In the atherosclerotic subjects, arterial endothelial cell injury and plaque formation are suspected to be strong causable factors in developing acute coronary syndrome, and it was revealed that platelets have a very important role in this case. Women are exposed to atherosclerosis at a different degree after menopause or oral contraception. The purpose of this study was to determine the effects of endogenous and exogenous estrogen on the degree of platelet aggregation in platelet rich plasma(PRP) in twenty nonsmoking healthy Korean women for 12 weeks. The subjects were assigned to three groups: (1) eight women aged 49 to 60(yr) for the postmenopausel(Pst) group, (2) eight, aged 22 to 30(yr) for the premenopausa(Pre) group, (3) four, aged 23 to 30(yr) for the oral contraceptive (OC) group which used triphasic OC formulation. Fasting blood sample were obtained from the subjects, (1) once per 6 weeks in the Pst group, (2) every phase of the menstrual cycle in the Pre group, (3) each once during and after OC administration in the OC group. ADP, collagen and epinephrine were used as aggregating reagents, and platelet aggregation and time(Δt: time reaching to the maximum point of aggregation) in PRP were measured at the maximum point of aggregation in five minutes. All the data were adjusted for dietary effects, personality type and body mass index(BMI) by using analysis of covariation(ANCOVA). Platelet aggregation to ADP and collagen(MADP and MCOLL) were not significantly different among the three groups, and Δt to ADP and collagen(TADP and TCOLL) were not either. But maximum platelet aggregability and Δt to epinephrine(MEPIN and TEPIN) were significantly different among the three groups, and the OC group showed the lowest value (p<0.01). Maxtimum platelet aggregability and Δt during the menstrual cycle were not significantly different in the Pre group. Any other significant differences in the maximum platelet aggregability and Δt were found between oral contraception phase and washing out phase(menstruation) in the OC group. In results, maximum platelet aggregability and aggregation time to ADP and collagen seemed not to be affected by endogenous and exogenous estrogen, even though MEPIN and TEPIN showed significantly low in the OC group among the three groups.

• 전기학회논문지P
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• 제61권4호
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• pp.168-173
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• 2012

The aggregation of group loads, which consists of the linear and the non-linear systems, yields the error involved in the reactive power aggregation, which is greater than the active power aggregation in the component based load modeling. Each individual reactive power in a group load affects the aggregated load different from composition rate. This paper proposes a new method that determines the degree of impacts by adjusting the coefficient of weight factors of each load using the least squares error method. The effectiveness of proposed algorithm is demonstrated by simulating three aggregation cases.

• 정보처리학회논문지B
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• 제8B권6호
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• pp.669-674
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• 2001

병합 과정에 병합 상황을 반영하기 위해 상황 평가에 기반을 둔 병합(ASA) 방법이 제안되었다.[1]. 상황 평가 모델의 정수화된 출력은 병합을 위한 입력으로 사용된다. 상황 평가 모델의 정수화된 출력은 현재의 병합 상황 정도를 나타낸다. ASA 알고리즘은 최소값과 최대값 사이에서 기껏해야 몇 개의 병합 결과를 만들어 낸다. 결과적으로 ASA 방법은 최소값과 최대값 사이에서 보다 더 정교한 병합 결과를 갖는 응용 분야를 적절히 다룰 수 없다. 이러한 문제를 해결하기 위해 두 가지의 개선된 ASA (I-ASA) 방법을 제안한다. 이들 I-ASA 방법에서는 상황 평가 모델의 매개변수의 값이 실수 값이 되는 것이 허용되고, 최소값과 최대값 사이에서 연속된 병합 결과를 만들 수 있게 하기 위해 두 가지의 개선된 ASA 알고리즘을 제시한다. 이들 I-ASA 방법들은 정밀 병합과 근사 병합을 다룰 수 있다. 결과적으로, ASA 방법[1]과 비교할 때 제안된 I-ASA 방법들이 보다 더 정교한 병합 결과를 갖는 응용 분야를 적절히 다룰 수 있고, 또한 보다 범용적인 병합 분야에 사용될 수 있다는 관점에서 장점이 있다.

• Journal of Nutrition and Health
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• 제32권4호
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• pp.384-393
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• 1999

The degree of platelet aggregation, thromboxane B2(TXB2)formation and fatty acid composition of platelet phospholipids(PL) were investigated in 24 healthy male subjects who for five weeks consumed either corn oil(CO) rich in linoleic acid(LA), perilla oil (PO) rich in $\alpha$-linoleic acid($\alpha$-LAN), or canola oil(CNO) rich in oleic acid(OA) as a major fat source. Total fat intake was 30% of total calories and prescribed oil intake of each dietary group was 50% of the total fat intake. In the CO group, significantly decreased contents of polyunsaturated fatty acids(PUFA), n-6 PUFA, n-3 PUFA and eicosapentanoic acid(EPA) were observed, and significantly increased contents of OA and saturated fatty acids(SFA) were observed in platelet PL after 3 weeks and 5 weeks of dietary treatment. In the PO group, contents of OA and docosahexanoic acid(DHA) were increased, and the ratio of n-6/n-3 was decreased significantly in platelet PL after dietary treatment. The CNO group showed significatnlty decreased contents of PUFA, P/S ratio, n-6 PUFA, LA,(EPA+DHA)/arachidonic acid(AA), and significantly increased SFA contents after 3 weeks of the oil-based diet. The dietary-induced effects on fatty acid composition of platelet PL were observed mostly after 3 weeks of the oil-based diet. The dietary-induced effects on fatty acid composition of platelet PL were observed mostly after 3 weeks. Plasma TXB2 levels were increased after 3 and 5 weeks of dietary treatment. However, only the CO and CNO groups showed significantly increased plasma TXB2 levles after 3 and 5 weeks of dietary treatment. However, only the CO and CNO groups showed significantly increased plasma TXB2 levels after 5 weeks of experimental diets, when compared with initial values. Degree of platelet aggregation increased only in the CO group after dietary treatment. As a result, at week 5 the degree of platelet aggregation of the CO group was significantly higher than those of the PO and CNO groups. Among the three oil-based diets, the PO-based diet seems to have beneficial effects on atherosclerosis by influencing plasma TXB2 levels and the degree of platelet aggregation, while the CO-based diet showed the most adverse effects. Our results imply that plasma TXB2 levels might be affected by dietary fatty acid composition.

• 자원리싸이클링
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• 제29권4호
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• pp.67-72
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• 2020

폐구리전선의 재활용 공정은 여러 단계의 절단공정으로 피복재로부터 구리선을 분리 후 비중선별공정으로 구리선을 회수하는 방법이 사용되고 있다. 구리세선은 이후의 재활용 공정에서 손실 등의 우려가 있어 추가적인 처리가 필요하다. 이 연구에서는 볼밀처리를 통해 구리세선의 응집체를 구성하여 손실을 방지하고자 하였다. 구리선의 응집은 구리선이 휘어져 서로 얽히는 과정에서 발생하므로 본 연구에서는 볼밀처리 후 구리전선의 굴곡도를 측정하였다. 0.5 cm와 3 cm의 구리세선을 사용하였을 때 볼의 투입과 상관없이 0.5 cm 구리세선은 휘지 않았고, 3 cm의 구리세선은 모두 응집되었다. 1 cm와 2 cm의 구리선을 사용하였을 때는 볼을 투입하였을 때 구리선의 휨 현상이 현저하였다. 2 cm의 구리세선을 사용한 실험에서 20 mm 알루미나 볼의 투입량을 증가시킴에 따라 구리선의 응집율은 점차적으로 증가하였고 30 mm 알루미나 볼을 사용하였을 때 200 ml 투입한 경우 응집율이 89.29 %로 증가한 후 볼 투입량을 증가시키면 응집율이 감소하였다. 이와 같이 구리세선을 볼밀 처리하면 구리세선의 응집체 형성이 가능하여 구리세선의 손실이 감소될 것으로 기대된다.

• Journal of Electrical Engineering and Technology
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• 제13권2호
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• pp.998-1007
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• 2018

The advent of Wireless Sensor Networks (WSN) has led to their use in numerous applications. Sensors are autonomous in nature and are constrained by limited resources. Designing an autonomous topology with criteria for economic and energy conservation is considered a major goal in WSN. The proposed honey-hive clustering consumes minimum energy and resources with minimal transmission delay compared to the existing approaches. The honey-hive approach consists of two phases. The first phase is an Intra-Cluster Min-Max Discrepancy (ICMMD) analysis, which is based on the local honey-hive data gathering technique and the second phase is Inter-Cluster Frequency Matching (ICFM), which is based on the global optimal data aggregation. The proposed data aggregation mechanism increases the optimal connectivity range of the sensor node to a considerable degree for inter-cluster and intra-cluster coverage with an improved optimal energy conservation.

• Asia pacific journal of information systems
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• 제10권3호
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• pp.181-197
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• 2000

The purpose of this study is to confirm whether the fit between the task and the information characteristics makes any effects on the user satisfaction. The task is defined as two sub-constructs representing the degree of exception and analyzability. The information characteristics is divided into the degree of aggregation, scope and timeliness of information. User satisfaction was used as a surrogate measure of the performance of information systems. The computer self-efficacy was used to control any confounding effects. Field research method using questionnaires was employed to empirically investigate the relationship among the variables. Findings of the study are summarized as follows: the fit between the task and the aggregation of information and between the task and the scope of information turned out to have significant effects on information system performance. The implication of such results is that under highly exceptional or less analyzable task environment, less-aggregated or broad information is more appropriate.

• Journal of Pharmaceutical Investigation
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• 제31권1호
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• pp.7-12
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• 2001

Amphotericin B (AmB) is a drug of choice for the treatment of systemic fungal diseases, but its use is considerably limited due to a high incidence of toxicity, particularly nephrotoxicity. It has been demonstrated that the toxicity of AmB is caused by self-aggregated species of the drug and that unaggregated (monomeric) drug is nontoxic but still expresses antifungal activity. Poly (ethylene oxide) (PEO) is a water-soluble polymer, which may impact the aggregation state of AmB. We have studied the aggregation state of AmB as a function of PEO molecular weight and concentration. At 3,000 and 8,000 g/mole, there was minimal or no change of critical aggregation concentration (CAC) of AmB regardless of the concentration of polymer. By contrast at 20,000 g/mole, the CAC of AmB strikingly increased to 24.3 and $37.5\;{\mu}M$ at 5.0% and 10 % w/v of polymer, respectively. The critical overlap concentration (COC) of PEO 20,000 g/mole was 5.5%. It appears that an interaction between monomeric AmB and polymer coil increases above the COC, competing with self-aggregation of the drug. Accordingly, the degree of aggregation of AmB stayed low and the toxicity became less. There was no such effect at 3,000 and 8,000 g/mole of PEO, owing perhaps to small dimensions in comparison to AmB. Based upon these findings, less toxic AmB formulation may be developed by a pharmaceutical technique such as solid dispersion system containing both AmB and PEO 20,000 g/mole.