• 한국응용과학기술학회지
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• 제38권2호
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• pp.368-377
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• 2021

본 연구는 방사선 형질전환 차조기와 백출복합물(차조기 복합물)이 퇴행성관절염 관련 매개체에 미치는 영향을 확인하고자 MIA(monosodium iodoacetate)로 퇴행성관절염을 유도한 랫드로 평가하였다. 차조기 복합추출물을 2주 동안 25, 50, 100 mg/kg/day의 용량으로 경구 투여하고 랫드의 우측관절 내 공간에 MIA를 주입한 후 동일 용량을 4주 동안 지속 투여하였다. 이후, 혈청 바이오마커와 무릎 관절 분석의 형태학 및 조직병리학적 분석에 기초한 치료 효과를 평가하였다. 대조군 랫드와 비교하였을 때 차조기 복합추출물은 혈청 내 염증 및 골 대사 마커(TNF-α, MMP-3, COX-2, PGE₂, COMP, Aggrecan)의 생성량을 유의하게 감소시켰다. 이와는 반대로 연골 흡수 매개체인 CTX-2 생성을 증가시켰으며, 방사선 형질전환 차조기는 무릎 연골과 활막을 효과적으로 보존하였다. 그 결과, 차조기 복합물은 퇴행성관절염 증상을 개선하였다. 따라서, 차조기 복합물은 퇴행성관절염 관리를 위한 식품소재로 사용될 수 있다.

• 대한족부족관절학회지
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• 제9권2호
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• pp.135-139
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• 2005

Purpose: This study was performed to investigate the radiological characteristics of the degenerative arthritis of the ankle using the standing radiographs. Materials and Methods: From June 2001 to May 2005, 36 patients (56 ankles) who were treated for osteoarthritis of ankle were analysed. Angle of tibial shaft and tibial joint surface on AP view (TSA), angle of tibial joint surface on lateral view (TLS), tibial and medial malleolus angle (TMM) and talo-1st metatarsal angle were checked on standing radiograph. The patients with medial joint and total joint involvement were categorized into three stages according to the location of involvement. The degree of joint space narrowing was categorized into two groups. Results: There were no significant differences in TSA, TLS, TMM and talo-1st metatarsal angle with regard to the stage of arthritis. However, the difference between the less severe group and the severe group existed. Conclusion: Angular deformity was not correlated with stage, but correlated with severity. The deformity of distal tibial articular surface does not seem to be a cause of primary osteoartiritis, but rather a result from it.

• 근관절건강학회지
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• 제16권2호
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• pp.116-124
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• 2009

Purpose: The purpose of this study was to examine the effects of a Tai Chi exercise program on physical function and physiological variables in patients with degenerative arthritis. Methods: The study utilized a nonequivalent control group with pretest-posttest design. Data collection was done with the elders from two welfare institutions in C-city between July I and September 22, 2007. The participants were assigned either to an experimental group (n=24) or to a control group (n=22). The experimental group participated in Tai Chi exercise for 60 minutes per session, twice a week for 12 weeks and the control group received the education about arthritis for 3 weeks. Results: Except for $VO_2max$, weight, and body fat rate, the elders in the experimental group showed significant improvement in physical function (grip strength, flexibility, balance), and physiological variables (BP) compared to the control group. Conclusion: The results suggest that Tai Chi exercise would partially improve physical function, and physiological variables. Further studies are needed to determine the effects on physical fitness and physiological variables after Tai Chi exercise in this population.

• 한국방사선학회논문지
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• 제12권3호
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• pp.397-402
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• 2018

본 연구는 엉치엉덩관절의 골절, 탈구, 엉치엉덩 퇴행성관절염 진단을 위한 가장 좋은 영상을 얻기 위해 골반 팬톰과 엑스선관을 각도 변화를 주어 엉치엉덩관절의 Joint space 가장 잘 나타내는 영상을 얻어 방사선사에게 주관적 평가를 받아 보았다. 평가 결과 결론으로 엉치엉덩관절염과 퇴행성 관절염 발견을 위한 단순촬영에서는 엎드린상태에서 촬영은 검사반대쪽 엉덩이를 $25^{\circ}{\sim}30^{\circ}$ 들어올리고 엑스선관을 앞엉덩뼈가 시에서 2.5 cm 안쪽을 지나는 시상면에 대해 수직촬영 하고 누운자세에서는 검사쪽 엉덩이를 $25^{\circ}{\sim}30^{\circ}$ 들어 올리고 위앞엉덩뼈가시가 중앙에서 위앞엉덩뼈가시가 중앙에 대해 엑스선관 각도를 발쪽으로 $5^{\circ}$ 촬영 하며 반드시 양쪽 엉치엉덩관절후전사방향(RAO,LAO) 및 전후사방향(RPO, LPO) 모두 촬영을 하게 되면 관절염 진단을 내리는데 있어 많은 도움이 되리라 본다.

• 대한한의정보학회지
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• 제14권2호
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• pp.79-93
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• 2008

Objectives : Taichi for arthritis was developed in 1997 by Paul Lam, M.D. of family medicine in Australia. It is an exercise treatment program and a good approaching method of the oriental medicine for arthritis. However, clinical and academical researches were rare. The purpose of this study is to investigate the effectiveness of the Taichi for arthritis. Methods : We used the medical literature search system, MEDLIS and the database of academic journal, DBpia to search medical studies published in korea. Keywords were "Taichi", "Tai Chi Chuan" and "Arthritis". We classified literatures with two criteria, year of publishment and study design. Then we classified as placebo design and summarized whole material. We determined its effectiveness by positive-negative results of Taichi for arthritis. Results : Taichi for arthritis could release pain of the rheumatoid or degenerative arthritis. Also it is thought to increase muscular power and enhance physical flexibility, balance. Conclusions : There were limits to ensure effectiveness because of small number of studies comparing Taichi with other exercise program for arthritis. However the Taichi for arthritis could have positive effect to treat the rheumatoid and degenerative arthritis. We hope further studies to be followed in oriental medical field.

• 한국운동역학회지
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• 제18권1호
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• pp.45-52
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• 2008

이번 연구는 퇴행성 슬관절염이 있는 여성환자 40명을 대상으로 키네시오 테이핑이 통증감소와 기능증진에 효과가 있는지 알아보고자 실시하였다. 테이핑치료의 효과에 대한 측정은 통증, 관절가동범위, 그리고 일어나 걸어가기 검사를 실시하였다. 그 결과 통증은 대조군에 비해 실험군이 더 유의하게 감소하였으며, 관절가동범위 역시 대조군에 비해 실험군이 더 유의하게 증가하였다. 일어나 걸어가기 검사의 시간은 두 군간에 유의한 차이가 없었지만, 보폭수는 실험군이 더 유의하게 감소하였다. 따라서 이번 연구결과를 통해 알 수 있는 것은 퇴행성 슬관절염 환자에게 키네시오 테이핑을 실시하게 되면 통증감소 및 기능증진에 효과적이라는 것을 알 수 있다.

• 한국식품영양과학회지
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• 제45권5호
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• pp.634-641
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• 2016

본 연구에서는 오디추출복합물(mulberry extract complex, MEC)의 퇴행성관절염 증상 완화 및 개선 효과 가능성을 탐색하기 위하여 monosodium iodoacetate(MIA)로 유도한 퇴행성관절염 in vivo 실험모델을 이용하였다. 연골의 주요 구성성분인 glycosaminoglycan(GAG) 및 collagen의 농도를 실험동물의 연골에서 측정한 결과 MIA로 인해 감소하였던 GAG 및 collagen의 농도가 MEC를 경구 투여한 실험군에서 농도 의존적으로 증가하였다. 또한 교원질 합성을 억제하고 분해를 촉진하는 matrix metalloproteinase-2, 9, 13의 농도를 측정한 결과는 MEC의 농도에 따라 감소하는 결과를 보여주었다. 연골 손상 지표인 cartilage oligomeric matrix protein과 C-terminal telopeptide 2의 측정결과에서는 대조군보다 유의성 있는 감소를 나타내어 MEC가 퇴행성관절염의 진행 억제에 도움을 줄 수 있을 것으로 생각된다. 관절염 지수 평가에서도 MEC는 모든 농도에서 대조군보다 유의성 있게 개선되는 결과를 나타내었다. 이상의 실험 결과를 통하여 MEC가 퇴행성관절염에서 나타나는 연골 구성성분의 분해를 억제하고, 여러 중요한 퇴행성관절염 진행 인자를 효과적으로 억제하여 결국 연골파괴 감소와 더불어 통증을 줄여줌으로써 퇴행성관절염에 대한 증상 완화 및 개선 효과가 있을 수 있는 건강기능식품의 원료로 활용될 수 있을 것으로 생각된다.

• 대한정형도수물리치료학회지
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• 제14권2호
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• pp.34-40
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• 2008

Purpose: We defined osteoarthritis of the knee as knee pain and crepitus in over 40 years old. The usual clinical manifestation include pain, stiffness, crepitus and loss of function. Methods: We studied 40 cases of the degenerative arthritis of knee clinically. The body mass index(BMI, weight(kg)/height($m^2$) was used as a measure of obesity. Pain self assessment scale by Million Index in according to age, occupation, BMI. Results: Gender by pain self assessment scale was 6.5 in male and 6.6 in female(P<0.05). The prevalence rates obese was 40%. Occupation by pain self assessment scale was 7.0 in Sitting and 5.7 in Standing(P<0.05). Prevalence was increased with age by pain self assessment scale in aged 40-69 years. Conclusion: It has been known that the obesity is one of the predispsing factors of the primary degenerative arthritis of knee. A flexion weight bearing view of the knee obtained at $30^{\circ}$ to $40^{\circ}$ of the joint flexion may be more sensitive in assessing damages to hyaline cartilage because the knee flexion is an important component of the stance phase.

• 대한물리치료과학회지
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• 제9권3호
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• pp.67-75
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• 2002

The purpose of this study was to evaluate the effects of quadriceps femoris flexibility exercise which would improve the degree of knee flexion range of motion, extension torque, and the activities of daily living (ADL) in elderly subjects with degenerative knee arthritis. Fourteen elderly patients (two men and twelve women) with degenerative knee arthritis participated and had a quadriceps femoris flexibility exercise intervention program in this study. The mean age of the patients was 70.00 years for men and 71.16 years for women. This study carried out the experimental study of one group pretest-posttest design, which evaluated the degree of knee flexion range of motion, extension torque, the ADL ability of the patients before and after applying the exercise intervention for five weeks. The results of this study are as follow: 1. The knee flexion ranges of motion of the patients were measured before and after the intervention and the ranges increased significantly both in the left and right knee flexion range of motion (p < 0.05). 2. The peak torque of the knee muscle, the peak torque/body weight, and average power of the patients showed significant increases in both in the left and right knee after applying the intervention (p < 0.05). 3. The intervention produced a significant reduction in pain of the patients (p < 0.05). Their functional activities of ADL improved significantly compared with before the intervention (p < 0.05). It has been shown that the quadriceps femoris flexibility exercise intervention program increased significantly the knee flexion range of motion, and extension torque, as well as an increase in performance of functional activities of ADL of the patients. Thus, the quadriceps femoris flexibility exercise should be considered as one of the therapeutic exercises for the elderly patients with degenerative knee arthritis applied.

• International journal of advanced smart convergence
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• 제7권2호
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• pp.55-66
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• 2018

Osteoarthritis is one of the most common chronic degenerative disease and prevalent among women in rural area. A variety of self-management programs for arthritis patients have been developed and administered, however the effectiveness and adherence to the program including arthritis exercise are found to be low. The purpose of this study is to design intervention Arthritis Self-Management Program with Tai Chi (ASMP-TC) through identifying and analyzing attributes influencing adherence exercise behavior in Korean older adult women with arthritis in rural area. For this, the existing and relevant evidence on arthritis self-management including exercise intervention were investigated, and then this study describes well-designed arthritis self-management program to provide the credibility and validity necessary for its interventions. In addition, this study try to propose a self-management program model of Tai Chi exercise for rural older adults to improve adherence based on the primary health care facility, which is vulnerable area in Korea.