• Proceedings of the Korea Concrete Institute Conference
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• 2006.05a
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• pp.366-369
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• 2006

Deformability of RC members in shear is controlled by governing failure modes and material strength. Shear strength of members in D-regions has been explained by a direct load path (direct strut or arch action) and indirect load path (fan action or truss action). Indirect load path including truss action and fan action rely on bond along tension ties. Generally, superposition of two actions results in total shear strength when shear failure modes control. The ultimate deformation depends on controlling failure modes and thereby, their force transfer patterns. Proposed models are capable of explaining of limited deformability of RC members in D-regions.

• Proceedings of the Korea Concrete Institute Conference
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• 2004.11a
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• pp.357-360
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• 2004

Estimation of deformation capacity of non-flexural reinforced concrete members is proposed using basic concepts of limit analysis and the virtual work method. This new approach starts with construction of admissible stress field as for an equilibrium set. Failure mechanisms compatible with admissible stress fields are postulated as for displacement set. It is assumed that the ultimate deformations as result of failure mechanisms are controlled by ultimate strain of concrete in compression. The derived formula for deformability of deep beams in shear shows reasonable range of ultimate displacement.

• Korea-Australia Rheology Journal
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• v.21 no.2
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• pp.127-133
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• 2009

Hemorheological results may be influenced by the time between blood sampling and measurement, and storage conditions (e.g., temperature, time) during sample delivery between laboratories may further affect the resulting data. This study examined possible hemorheological alterations subsequent to storage of rat and dog blood at room temperature ($22^{\circ}C$) or with cooling ($4{\sim}10^{\circ}C$) for 2, 4, 6, 24, 48 and 72 hours. Measured hemorheological parameters included hematological indices, RBC aggregation and RBC deformability. Our results indicate that marked changes of RBC deformability and of RBC aggregation in whole blood can occur during storage, especially for samples stored at room temperature. The patterns of deformability and aggregation changes at room temperature are complex and species specific, whereas those for storage at the lower temperature range are much less complicated. For room temperature storage, it thus seems logical to suggest measuring rat and dog cell deformability within 6 hours; aggregation should be measured immediately for rat blood or within 6 hours for dog blood. Storage at lower temperatures allows measuring EI up to 72 hours after sampling, while aggregation must be measured immediately, or if willing to accept a constant decrease, over 24~72 hours.

• Korea-Australia Rheology Journal
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• v.16 no.3
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• pp.141-146
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• 2004

Shear-induced damage of Red Blood Cell (RBC) is an imminent problem to be solved for the practical application of artificial organs in extra corporeal circulation, as it often happens and affects physiological homeostasis of a patient. To design and operate artificial organs in a safe mode, many investigations have been set up to correlate shear and shear-induced cell damage. Most studies were focused on hemolysis i.e. the extreme case, however, it is important as well to obtain a clear understanding of pre-hemolytic mechanical damage. In this study, the change in deformability of RBC was measured by ektacytometry to investigate the damage of RBC caused by shear. To a small magnitude of pre-shear, there is little difference, but to a large magnitude of pre-shear, cell damage occurs and the effect of shear becomes significant depending on both the magnitude and imposed time of shearing. The threshold stress for cell damage was found to be approximately 30 Pa, which is much less than the threshold of mechanical hemolysis but is large enough to occur in vitro as in the extra corporeal circulation during open-heart surgery or artificial heart. In conclusion, it was found and suggested that the decrease of deformability can be used as an early indication of cell damage, in contrast to measuring plasma hemoglobin. As cell damage always occurs during flow in artificial organs, the results as well as the approach adopted here will be helpful in the design and operation of artificial organs.

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.1682-1686
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• 2004

A slit-flow apparatus with laser diffraction method has been developed with significant advances in ektacytometry design, operation and data analysis. In the slit-flow ektacytometry (or laser-diffractometry), the deformation of red blood cells subjected to continuously decreasing shear stress in slit flow is measured. A laser beam traverses a diluted blood suspension flowing through a slit and is diffracted by RBCs in the volume. The diffraction patterns are captured by a CCD-video camera, linked to a frame grabber integrated with a computer, while the differential pressure variation is measured by a pressure transducer. Both measurements of laser-diffraction image and pressure with respect to time enable to determine deformation index and the shear stress. The range of shear stress of 0 ${\sim}$ 35 Pa and measuring time is less than 2 min. When deforming under decreasing shear stress, RBCs change gradually from the prolate ellipsoid towards a circular biconcave morphology. The Deformation Index (DI) as a measure of RBC deformability is determined from an isointensity curve in the diffraction pattern using an ellipse-fitting program. The advantages of this design are simplicity, i.e., ease of operation and no moving parts, low cost, short operating time, and the disposable kit which is contacted with blood sample.

• Computers and Concrete
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• v.16 no.4
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• pp.625-642
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• 2015

Prestressed concrete bridges with corrugated steel webs have emerged as one of the promising bridge forms. This structural form provides excellent structural efficiency with the concrete flanges primarily taking bending and the corrugated steel webs primarily taking shear. In the design of this type of bridges, the flexural ductility and deformability as well as strength need to be carefully examined. Evaluation of these safety-related attributes requires the estimation of full-range behaviour. In this study, the full-range behaviour of beam sections with corrugated steel webs is evaluated by means of a nonlinear analytical method which uses the actual stress-strain curves of the materials and considers the path-dependence of materials. In view of the different behaviour of components and the large shear deformation of corrugated steel webs with negligible longitudinal stiffness, the assumption that plane sections remain plane may no longer be valid. The interaction between shear deformation and local bending of flanges may cause additional stress in flanges, which is considered in this study. The numerical results obtained are compared with experimental results for verification. A parametric study is undertaken to clarify the effects of various parameters on ductility, deformability and strength.

• 순환기질환의공학회:학술대회논문집
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• 2005.12a
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• pp.7-8
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• 2005

• The Korean Journal of Physiology
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• v.25 no.2
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• pp.101-113
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• 1991

• 순환기질환의공학회:학술대회논문집
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• 2004.11a
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• pp.52-53
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• 2004

• 순환기질환의공학회:학술대회논문집
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• 2003.11a
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• pp.42-43
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• 2003