• Korean Journal of Psychosomatic Medicine
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• v.19 no.2
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• pp.109-114
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• 2011

The abnormalities in Hypothalamic-pituitary-adrenal(HPA) axis are associated with many psychiatric symptoms including depression. We present a report of a 71 year old man who was admitted to the psychiatric department presenting symptoms of headache, avolition, loss of energy, psychomotor retardation, poor appetite, insomnia, anxiety resulting from adrenal insufficiency and hypopituitarism. Hypothyroidism and electrolyte disturbance were managed and headache, insomnia, anxiety, GI symptoms were improved. But he remained in anergic state. After discharge, he was readmitted to infection department with high fever and drowsy mentality. Adrenal insufficiency was recognized and he was treated with corticosteroid replacement therapy. Finally his diagnosis was made as panhypopituitarism and overall symptoms were resolved. In this case, we showed how the atypical symptoms resulting from hypopituitarism develop and progress. Hypothyroidism, adrenal insufficiency, and growth hormone deficiency resulting secondarily from panhypopituitarism were associated with various nonspecific symptoms such as loss of energy, fatigue, insomnia, weight loss, decreased appetite etc. In clinical situation, differential diagnosis with depression is needed when clinicians were met a patient with these nonspecific symptoms. It is important that laboratory tests and differential diagnosis with endocrine diseases should be conducted, especially in geriatric patients with nonspecific symptoms like anergia, fatigue, poor appetite and so on.

• Journal of Veterinary Clinics
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• v.28 no.6
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• pp.581-585
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• 2011

Either the fasting during natural molting or the starvation in induced molting would be a severe metabolic stress to laying hens. The metabolic stress during starvation and subsequent refeeding syndrome could lead to unbalance of mineral homeostasis, including $Mg^{2+}$, $K^+$ and P required by ATP synthesis. Since $Mg^{2+}$ is a fundamental ion for normal metabolic processes and stress may not only increase in demands of $Mg^{2+}$ but also produce consequence of $Mg^{2+}$ deficiency, we investigated the changes of blood ionized and total ions related to starvation during molting in laying hens. We founded the significant decrease in blood $Mg^{2+}$ and $K^+$ accompanied by the changes of biochemical parameters relating to increased metabolic stress after molting. These results suggested that appropriate $Mg^{2+}$ and $K^+$ supplements to laying hens could have beneficial effects during molting and subsequent refeeding that could produce a severe hypomagnesemia and hypokalcemia.

• Journal of Korean Society for Geospatial Information Science
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• v.6 no.2 s.12
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• pp.69-79
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• 1998

It is one of the most crutial thing to secure efficient infrastructure of social infrastructure Including rna drinking water, sewer, gas, and electricity, etc. in modern society. Among them, the sourer system need to be properly maintained so as to sustain water quality over the large watershed thereby to provide reasonable level of living environment A few municipalities and private firms have so in been using sewer management system for assessing existing sewer network and auxiliary facilities. Such existing system can only provide functions to manage the sewer pipe itself and they can not fully estimate the amount of sewage water over the pipe through 4he network analysis due to the deficiency of the system Such a limited sewer network analysis function can only analyze the whole network under the assumption of uniformity. The results from such a process can not be fully implemented in the field. Therefore, this study emphasized the development of a sewer management system which can provide practical values from network analysts considering areal peculiarities using a zoning map utilizing a GIS. The system can support analyzing scenarios due to the changes of sewer amounts from the changes of population densities and rainfall amounts not to mention of calculating sewer amount for individual sewer pipes. furthermore, the system can support the decision making for better designing sewer facilities from the expansion of metropolitan areas and constructing satellite cities. Eventually, it will contribute to enhance the effectiveness of sewer-related works and services for residents as well as supporting a decision making for minor and major trouble-shootings.

• Journal of The Korean Association For Science Education
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• v.41 no.5
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• pp.391-400
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• 2021

This study investigated science education experts' perception of remote laboratory sessions (RLS) provoked by the COVID-19 pandemic. We conducted a total of 10 semi-structured interviews with experts in physics, chemistry, biology, and earth science education. As a result, science education experts primarily understood the RLS concerning pre-service teacher education and reconsidered the aim and goal of conventional laboratory education. On practices of RLS provoked by the COVID-19, they pointed out the learning loss due to deficiency of hands-on experience, decreased interactions between instructor and students, and instructors' increased burden. Meanwhile, they contemplated upon their adaptive implementation of RLS to suggest ways to improve RLS instruction and directions of post-COVID-19 science education. We recommend that RLS should be understood as a complemented version of minds-on teaching rather than a degraded version of hands-on teaching to elicit its full potentials. This study has its own significance providing an in-depth science educational perspective interpreting the RLS phenomena.

• Journal of Korean Society for Geospatial Information Science
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• v.20 no.2
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• pp.3-13
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• 2012

This study evaluated the feasibility of the location for PM-10 Monitoring Stations utilizing through GIS analysis. In addition, optimal sites were investigated to properly manage PM-10 which are closely related with public health. There are 11 PM-10 monitoring stations in Daegu area and the PM-10 data monitored at these stations are utilized to understand the overall status of PM-10 pollution. However, there are contrastive issues on the locations of current monitoring stations. Thus, this study prepared the map of PM-10 concentrations in Daegu area using IDW and Kriging techniques. Furthermore, average PM-10 concentrations were calculated using zonal statistical methods according to legal divisions and then, the current monitoring stations were evaluated whether their location is appropriate or not for PM-10 pollution distribution. It was found that, on the basis of yearly, seasonal and daily concentration analysis, the location of current PM-10 monitoring stations were not appropriate, particularly as they could not represent regional PM-10 pollution characteristics. In order to supplement this deficiency, seven sites(Namsandong, Namildong, Dongildong, Buksungro 1, Jongro 1, Hyangchondong and Haejeondong) commonly selected from each analytical step are suggested as additional PM-10 monitoring sites. It is further suggested that this kind of scientific evaluation for the location of PM-10 monitoring stations are needed in order to properly manage public heath in other cities as well as Daegu area.

• Korean Journal of Veterinary Research
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• v.15 no.2
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• pp.147-152
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• 1975

Although considerable research has been done on the blood picture of the horse, hot-blooded and cold-blooded, little work has been made of the blood picture of the army pack horse, Jeju horse. The object of the present investigation was to make good this deficiency, and to suggest standard for the blood picture of army pack horses kept under the regular military training and the ideal feeding in the heart of a mountain. Blood samples were drawn from the jugular vein through a 15-gauge bleeding needle from 41 males and 28 females, aging 3 to 9 years old. It was taken between seven and nine o'clock in the morning. Animals were handled as quietly as possible to avoid any excitation. No restraint other than a halter was used. Enumeration of erythrocyte, total and differential leukocyte count, determination of hemoglobin in blood, and the value of packed cell volume were male in the usual manner, and erythrocytic constant was calculated by the method of Wintrobe. Erythrocyte count was $7.83{\pm}0.20(4.95{\sim}11.05){\times}10^6/mm^3$(SE). This value was much lower than hot-horses, but slightly higer than the values of cold-horse reported from foreign country. Concentration of hemoglobin in blood was $13.0{\pm}0.33(9.5{\sim}17.8)g/100ml$. This value was much higher than that of cold-horses observed by the other authors, approaching to the values of hot-horses. Packed cell volume was $32.1{\pm}0.92(22{\sim}42)ml/100ml$. This vague was a little higher than that of the other cold-horses. Mean corpuscular volume was $41.5{\pm}1.20(26.6{\sim}59.3){\mu}m^3$. This value matched so well with the other results recorded by various investigators. Mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration were $16.9{\pm}0.43(12.3{\sim}25)$ pg and $41.0{\pm}0.45(29.1{\sim}51.1)g/100ml$, respectively. These values were significantly higher than the values found by the other investigations. Total leukocyte enumeration was $10.5{\pm}0.41(5.6{\sim}17.9){\times}10^3/mm^3$, being considered as normal. And differential leukocyte count of neutrophil was $44.5{\pm}2.23(15{\sim}76)%$, $5,527{\pm}234(2,231{\sim}9,144)/mm^3$, of lymphocyte $50.5{\pm}1.19(19{\sim}77)%$, $4,307{\pm}125(1,456{\sim}11,098)/mm^3$, of monocytel (0~4)%, $105(0{\sim}352)/mm^3$, of eosiophil 3.2(0~14)%, $340(0{\sim}1,232)/mm^3$ and of basophil 0.25(0~3)%, $23(0{\sim}236)/mm^3$. The percentage of the differential count obtained from the present work showed a good agreement with the results of various authors. Of the horses examined monocyte was found from 42 horses, eosinophil from 62 horses and basophil from 10 horses. No significant differences recognized between male and female horses, and the effect of age was not observed between three to nine years old. Judging from the blood picture of the present investigation, it could be stated that the army pack horses on training were kept better than the average farming conditions.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.69 no.3
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• pp.163-169
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• 2024

Recent agricultural practices have depleted micronutrients in the soil, exposing approximately two billion people worldwide to "hidden hunger", a condition in which sufficient calories are consumed but there is a deficiency in essential vitamins and minerals. This form of malnutrition occurs not only in developing countries but also in developed nations where staple foods include grains such as wheat and corn. Among cereal crops, the color of wheat grains can vary due to the presence of different pigments in the bran layers. Colored wheat, rich in functional compounds such as anthocyanins, offers various health benefits primarily due to its antioxidant properties. Therefore, this study aims to evaluate the phenotypic and nutritional characteristics of wheat germplasm 'IT016425' compared with domestic wheat cultivars, with the intention of considering the introduction of this germplasm for breeding purposes. In the field trial, 'IT016425' had a heading date and maturity that were 22 and 8 days later than 'Keumgang', respectively. 'IT016425' also presented the tallest plant height (105.1 cm) but the shortest spike length (7.8 cm) and spike number (14 per plant). The thousand grain weight was similar to that of 'Tapdong', measuring 39.0 g. 'IT016425' had the lowest protein content, with a mean value of 12.1%, whereas 'Keumgang' had the highest protein content (15.5%). However, 'Tapdong' and 'IT016425' compensated for their lower protein content by having higher levels of total dietary fiber. These cultivars exhibited the highest total dietary fiber content, with mean values of 3.16 and 3.29 g/100 g, respectively, whereas 'Keumgang' and 'Arijinheuk' had lower values. 'IT016425' also had the highest content of anthocyanin, with a mean value of 1.61 mg/100 g. Additionally, 'IT016425' had the highest levels of minerals such as K (230.64 mg/100 g), P (190.31 mg/100 g), Mg (45.40 mg/100 g), Zn (1.06 mg/100 g), Mn (0.54 mg/100 g), and Cu (0.12 mg/100 g) compared to the other tested cultivars. Cultivating 'IT016425' in Korea may not be suitable due to the common practice of rice-wheat double-cropping, as it has delayed heading and maturity. However, considering its high anthocyanin and mineral content, it is necessary to introduce the beneficial traits of 'IT016425' into breeding programs.

• Journal of The Korean Association For Science Education
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• v.37 no.2
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• pp.347-358
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• 2017

The purpose of this study is to research on the professional development of pre-service chemistry teachers in terms of personal practical knowledge(PPK), and draw a discussion for pre-chemistry teacher education. A reflective discussion through a Community of Practice(CoP) activity has been conducted with 5 pre-service chemistry teachers studying in a college of education located in Seoul. The analysis of the results reveals that 'Subject-matter knowledge' is leaning toward massive chemical contents, 'Curriculum knowledge' is below the level of selecting, analyzing, and applying curriculum materials. 'Instruction knowledge', especially the knowledge of chemistry experiment and research, is not enough to lead secondary students' scientific experiment. 'Milieu of school knowledge' is stunted in growth for the reason of communication-deficiency between a college of education and a community, and among education- related groups. 'Self-knowledge' has been diminished not only because there is a bad influence from college classmates not wanting to be a teacher, but also a lack of communication in the chemistry-education department which can make pre-teachers' belief strong. In conclusion, it is especially needed for the chemistry-education department to strengthen pre-teachers' 'Self-knowledge' in order to develop PPK. This study suggests operating 'a professional community' that has a periodic meeting with pre-service teachers, teachers, professors, community people, education practitioners, and researchers. In addition, it would be effective for increasing pre-teachers' PPK to reconsider depth and direction of 'Subject-matter knowledge', to give an opportunity to examine curriculum materials critically and reorganize them, to improve the course of chemistry experimental subject to the way of improving pre-teachers' leadership in chemistry inquiry experiment, and to raise the quality of educational service activities.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.3 no.1
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• pp.68-74
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• 2000

Purpose: This study was to investigate the clinical manifestations of FTT in children. Methods: From March 1997 to July 1999, clinical observations were made on patients with FTT who had visited to Samsung Medical Center. Detailed histories and through physical examinations were taken, and when suspected organic FTT, basic laboratory studies were done. Results: Upon the review of medical records, we investigated the clinical manifestations of 74 children, aged 1 month and 13 year 1 month. The causes of FTT were composed of either physiologic (47.8%) or pathologic (52.2%) ones. Among the physiologic FTT, were there familial short stature (FSS, 14.5%), intrauterine growth retardation (IUGR, 14.5%), constitutional growth delay (CGD, 11.6%), idiosyncrasy and prematurity. Among pathologic causes, neurologic disorders (20%) are the most common causes of FTT, and then follow by GI (13.4%), allergic and infectious disorders in decreasing order. The data showed that average caloric intake in patients with FTT was 76,2% of recommended amount. FTT patients with CGD, IUGR, and idiosyncrasy had tendency to take small foods. The FTT children with prematurity, IUGR and pathologic FTT, were short and thin for their ages. However FTT children with CGD and FSS had tendency to be thin with relatively normal heights for their ages, in comparison with those of the children with prematurity, IUGR and pathologic FTT. Conclusion: The diagnosis of FTT was easily obtained with simple and through medical history, physical examination, and minimal laboratory tests. In this study, organic FTT was more prevalent than physiologic one. This results indicate that early intervention is mandatory, because children may develop significant long-term sequelae from nutritional deficiency.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.14 no.2
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• pp.135-141
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• 2014

Objectives: Fabry disease (FD) is a lysosomal storage disease caused by the inappropriate accumulation of globotriaosylceramide (Gb3) in tissues due to a deficiency in the enzyme ${\alpha}$-galactosidase A. Hypertrophic cardiomyopathy is one of the chronic complications of FD. We tried to evaluate the prevalence of Fabry disease in the Korean patients with left ventricular hypertrophy (LVH). Methods: A total of 257 patients with LVH were recruited and they were 172 males (mean 56 years, range 30-81 years) and 84 females (mean 66 years, range 45-85 years). Urinary Gb3 was used to screen FD by high performance liquid chromatography-tandem mass spectrometry. Confirmatory tests were done by alpha-galactosidaseA activity using fluorometric assay and by GLA mutation analysis using sequencing. Results: Four patients were screening positive by urinary Gb3 analysis (cutoff, 25 ug/mmol creatinine). But, one female patient was diagnosed with FD confirmed by enzyme analysis in leukocytes as well as by genetic analysis (1/257 patients, 0.4%). She showed 54.3 ug/mmoL creatinine of Gb3 and 15.5 nmole/hr/mg protein (reference range, $55.2{\pm}12.7nmole/hr/mg$ protein) of alphagalactosidase A activity. And she had a heterozygous GLA mutation of c.796G>A (p.D266N). Her daughter was found to be a carrier for FD confirmed by GLA mutation analysis. Asymptomatic carrier showed 25.5ug/mmol creatinine of Gb3 and 42.5 nmole/hr/mg protein (reference range, $55.2{\pm}12.7nmole/hr/mg$ protein) of alpha-galactosidase A activity. Conclusions: The prevalence of FD in Koran patients with LVH was detected as 0.4%. Although the prevalence seems to be low, screening studies are of great importance for detecting hidden cases as well as for identifying other effected family members.