• 생약학회지
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• 제50권2호
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• pp.73-80
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• 2019

Adenophora stricta Miq. (Campanulaceae) is an annual herb, which has been used as a traditional medicine in Korea, Japan and China to treat bronchial asthma, tonsillitis, and hypertension. In this study, 12 compounds were isolated from the roots of A. stricta and isolates were identified to be methyl adenophorate (1), decursidin (2), L-tryptophan (3), D-1,2,3,4-tetrahydronorharmane-3-carboxylic acid (4), vanillic acid 4-O-${\beta}$-D-glucopyranoside (5), syringic acid 4-O-${\beta}$-D-glucopyranoside (6), vanillin (7), vanillic acid (8), p-hydroxybenzaldehyde (9), p-hydroxybenzoic acid (10), p-hydroxyacetophenone (11) and linoleic acid (12). Decursidin (2) and D-1,2,3,4-tetrahydronorharmane-3-carboxylic acid (4) is firstly reported from A. stricta in current study.

• 생약학회지
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• 제19권4호
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• pp.233-238
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• 1988

Angelica flaccida Kom. is a herbal plant growing wild in the marsh of valley in Korea. It has been used for sedative and analgesic as a folk medicine, but its constituents have not been clarified yet. Five known coumarins such as isoimperatorin, decursidin, (-) anomalin, decursin, decursinol and two sterols such as ${\beta}-sitosterol$ and stigmasterol were isolated from the root of this plant, Their structures were identified by the UV, IR, NMR, mass data and the physico-chemical properties.

• 생약학회지
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• 제25권4호통권99호
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• pp.311-318
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• 1994

From the root of Angelica decursiva-albiflora Yook, which has been used as a folk medicine for a sedative, analgesic and expectorant, four free coumarins, e.g., decursidin(I), decursin(II), umbelliferone(III) and nodakenetin(IV), and two coumarin glycosides, e.g., nodakenin(V) and decuroside I(VI) were isolate. The cytotoxicity of nodakenin(V) against L-1210 leukemia cells was less effective than cisplatin, but in the nephrotoxicity against rabbit kidney proximal tubular cell nodakenin(V) showed remarkably less nephrotoxicant than cisplatin.

• 생약학회지
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• 제4권4호
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• pp.189-190
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• 1973

Silica gel column chromatography on the ether extract from the fruits of Angelica gigas $M_{AKAI}$ gave two kinds of crystalline constituents. The following derivatives of coumarins were identified by IR, NMR spectra, elemental analysis and physico-chemical tests: iso-imperatorin $(mp\;108{\sim}109^{\circ},\;C_{16}H_{14}O_4)$ and decursidin $(mp\;60{\sim}61^{\circ},\;C_{24}H_{26}O_7)$.

• 생약학회지
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• 제4권4호
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• pp.191-192
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• 1973

Silica gel column chromatography of the ether extract of the root of Angelica decursiva $F_{RANCHET}\;et\;S_{AVATIER}$ form. albiflora $N_{AKAI}$ (Umbelliferae) gave four kinds of crystalline products of pyranocoumarin and furocoumarin: decursidin $(mp\;60{\sim}61^{\circ},\;C_{24}H_{26}O_7)$, decursin$(mp\;110{\sim}111^{\circ},\;C_{19}H_{20}O_5)$, umbelliferone $(mp\;227{\sim}228^{\circ},\;C_{9}H_{6}O_3)$, and nodakenetin $(mp\;187{\sim}189^{\circ},\;C_{14}H_{14}O_4)$. Besides, the methanol extract of the root was found to contain sucrose.