• International Journal of Highway Engineering
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• v.16 no.5
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• pp.29-38
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• 2014

PURPOSES : The purpose of this study is to evaluate moisture susceptibility of a dense graded and an open graded asphalt mixtures by the method of AASHTO T-283. METHODS : To simulate moisture damage of asphalt pavements with continuously rainfall during summer rainy season, the dense graded and the open graded asphalt mixtures were immersed in water for 15 days and were measured the weight and the change of strength. Also, the mixtures were performed five freeze-thaw cycles to simulate moisture damage of the mixtures by freeze-thaw during winter and were measured the change of strength. The degradation characteristics model was used to analyze the relationship between strength and moisture damage. RESULTS : According to the results, the dense graded and the open graded asphalt mixtures were shown in the similar trends of the strength changes by immersion time and freeze-thaw cycle. However, the moisture damage reduction of open graded asphalt mixture was more sensitive in early phase than that of dense graded asphalt mixture.

• Archives of Plastic Surgery
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• v.45 no.4
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• pp.375-378
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• 2018

In this report, we present a case of successful treatment of a bowel fistula in the open abdomen by perforator flaps and an aponeurosis plug. A 70-year-old man underwent total gastrectomy and developed anastomotic leakage and dehiscence of the abdominal wound a week later. He was dependent upon extracorporeal membrane oxygenation, continuous hemodiafiltration, and a respirator. Bowel fluids contaminated the open abdomen. Two months after the gastric operation, a plastic surgery team, in consultation with general surgeons, performed perforator flaps on both sides and constructed, as it were, a bridge of skin sealing the orifice of the fistula. The aponeurosis of the external oblique muscle was elevated with the flap to be used as a plug. The perforators of the flaps were identified on preoperative and intraoperative ultrasonography. This modality allowed us to locate the perforators precisely and to evaluate the perforators by assessing their diameters and performing a waveform analysis. The contamination decreased dramatically afterwards. The bare areas were gradually covered by skin grafts. The fistula was closed completely 18 days after the perforator flap. An ultrasound-guided perforator flap with an aponeurosis plug can be an option for patients suffering from an open abdomen with a bowel fistula.

• Journal of Chest Surgery
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• v.14 no.3
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• pp.247-253
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• 1981

A total and consecutive 46 patients have undergone cardiac valvular surgery including 8 open mitral commissurotomy and 38 mitral, aortic, mitral-aortic, mitral-tricuspid, tricuspid valve replacements using 46 artificial valves in a period between September 1976 and July 1981. They were 19 males and 27 females with the age ranging from 16 to 50 (mean 32.6) years. Out of 46 valves replaced, 6 were prosthetic valves and 40 were tissue valves, and 33 were replaced in mitral, 9 in aortic and 3 In tricuspid position. Isolated replacements were 33 mitral valves, 6 aortic valves and 1 tricuspid valve; double valve replacements were 6 mitral-aortic valves and 2 mitral-tricuspid valves. . Early mortality within 30 days after operation was noted in 4 cases; 3 after MVR and 1 after open mitral commissurotomy. Causes of death were thrombus obstruction of Beall-Surgitool, Cerebral air embolism, acute renal shut down due to low output syndrome, and left upper pUlmonary vein rupture after open mitral commissurotomy (early mortality 8.7%). 3 late deaths were noted during the follow-up period from 2 to 59 months; 1 due to cerebral hemorrhage from warfarin overdose 3 months, 1 due to miliary tuberculosis 9 months, and another 1 due to cardiac failure after open mitral commissurotomy 42 months postoperatively. Total survival rate 59 months after valvular surgery was 84.8%; there were no early and late death in the group of AVR, TVR and double valve replacements. Preoperative NYHA Class III & IV were 35 cases (76%) out of total 46 cases, and 38 cases (94.8%) out of 39 survival cases were included In NYHA Class I & II during the follow-up period.

• Journal of Ginseng Research
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• v.31 no.4
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• pp.217-221
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• 2007

Ginseng has been widely used for the management of anxiety and emotional instability, but there is little experimental evidence supporting these clinical applications. The anxiolytic-like effect of ginseng saponin and polysaccharide fractions of white (WG) and red ginsengs (RG) was investigated using the elevated plus-maze test. The saponin (SF) and polysaccharide (PF) fractions were orally administered to male ICR mice for 3 days and behavioral test for the anxiolytic activity were performed. SF significantly increased the time-spent open arms and number into the in the open arm entries. However, PF weakly increased the time-spent in the open arms, but did not increase number into the open ann entries. The WG showed more potent anxiolytic-like effect than that of RG. The anxiolytic-like activities were antagonized by flumazenil, but not by esmolol. These findings suggest the saponin fractions of WG and RG promote the anxiolytic-like activity by antagonizing GABN/benzodiazepine receptors in mice.

• The Korean Journal of Pain
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• v.34 no.2
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• pp.165-175
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• 2021

Background: Management of pain from open wounds is a growing unmet healthcare need. However, the models available to study pain from wounds or to develop analgesics for the patients suffering from them have primarily relied on incisional models. Here, we present the first characterized and validated model of open wound pain. Methods: Unilateral full-skin excisional punch biopsy wounds on rat hind paws were evaluated for evoked pain using withdrawal responses to mechanical and thermal stimulation, and spontaneous pain was measured using hind paw weight distribution and guarding behavior. Evaluations were done before wounding (baseline) and 2-96 hours post-wounding. The model was validated by testing the effects of buprenorphine and carprofen. Results: Pain responses to all tests increased within 2 hours post-wounding and were sustained for at least 4 days. Buprenorphine caused a reversal of all four pain responses at 1 and 4 hours post-treatment compared to 0.9% saline (P < 0.001). Carprofen decreased the pain response to thermal stimulation at 1 (P ≤ 0.049) and 4 hours (P < 0.011) post-treatment compared to 0.9% saline, but not to mechanical stimulation. Conclusions: This is the first well-characterized and validated model of pain from open wounds and will allow study of the pathophysiology of pain in open wounds and the development of wound-specific analgesics.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.32 no.1
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• pp.115-132
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• 2021

This study collected data on COVID-19 research papers published in international journals by Korean authors from WoS. Bibliographical analysis was performed on subject categories, institutions, funder distribution and so on. In addition, open access and journal review speed were also analyzed, which play an important role in facilitating academic publishing and distribution. The results showed that COVID-19-related papers published in international journals by Korean authors in 2020 included more papers on some specific fields, such as medicine, biology, and multidisciplinary. These researchers have published lots of papers not only in foreign journals but also in domestic English journals. 94% of papers were open access, and gold open access, which is available immediately after publication, was about 70% of the total. The COVID-19 orthopedic papers produced by Korean researchers were collected from PubMed and analyzed, and the average of review days was about 24 days. The analysis, including open access and review speed, showed that there has been an atmosphere of cooperation in the academic publishing ecosystem after the COVID-19 crisis. It would be desirable to continue this cooperation and address chronic problems in academic publishing system, such as promoting the publication of gold open access and reviewing efficiency.

• Korean Journal of Environmental Agriculture
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• v.29 no.4
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• pp.348-353
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• 2010

The current study investigated the fate of organic matter in piggery slurry under two different store systems(closed store system and open store system) in association with different temperature. Thirty days after storing in both systems at $20^{\circ}C$, it was observed that the content of organic matter remained in piggery slurry with closed store system was twice more than that with open store system implying more efficient degradation of organic matter with open store system. Temperature also influenced on the organic matter degradation in piggery slurry as shown decline in TS and VS contents as the temperature increased. With store at $35^{\circ}C$, 29% of initial organic matter was reduced while there was only 23% reduction of organic matter at $20^{\circ}C$. There was no difference in the type of organic fatty acids(VFAs) produced under the range of temperature(20, $35^{\circ}C$) simulating summer condition. Increases in organic fatty acids contents with hydrolysis and acid producing microbial was observed from 15 days after initiating store of the piggery slurry and the total organic acid amount produced 30 days after store was $2,829\;mg{\cdot}COD/L$ and $9,123\;mg{\cdot}COD/L$ at $20^{\circ}C$ and $35^{\circ}C$, respectively. These corresponded to 5.4% and 17.4% of the initial organic matter contents in piggery slurry, respectively.

• Journal of Veterinary Clinics
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• v.30 no.3
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• pp.218-221
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• 2013

A flightless brown hawk owl (Ninox scutulata) weighing 180 g was rescued and referred to the teaching veterinary hospital with humerus open fracture. On physical examination and radiography, open fracture of the left humerus was found. After 3 days, orthopedic surgery was operated with intramedullary pins and wires. The bird died 2 days after surgery with anorexia. On necropsy, multiple green nodules with 2-3 mm in diameter were observed at the surface and inside of the left lung. Numerous conidial heads and spores were seen in the center of foci in the histopathological examination. The mycelia penetrated the surrounding pulmonary parenchyma, showing inflammation and necrosis. The fungus was isolated from the lung and cultured on Sabouraud Dextrose Agar at $30^{\circ}C$ for 7 days. The colony was blue-green color with a powdery surface. The fungus was identified as Aspergillus fumigatus by DNA analysis, including the internal transcribed spacer region, partial ${\beta}$-tubulin, and the calmodulin gene. This case was diagnosed as pulmonary aspergillosis secondary to open fracture of pneumatic bone in a brown hawk owl.

• Journal of Family Resource Management and Policy Review
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• v.20 no.3
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• pp.25-43
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• 2016

This study focused on the time use of a dual-earner working group with preschool children on working and nonworking days using 2014 time-use survey data provided by Statistics Korea(KOSTAT). We collected the time-use data recorded in a 2,158 time diary. We divided the time use into 4 parts ; paid work, household labor work (including caring work), leisure and living essentials. For the statistical analysis, we used SPSS 18.0 packages, i.e., descriptive statistics, T-test, Anova with Duncan test and regression for the impact off the independent factors. The results verified gender differences in time use and recognized the usefulness of the time-allocation analysis for the diagnosis of Work and Life Balance(WLB). In the conclusion, we suggest increasing men's time allocation for household labor as a crucial solution to the WLB of dual-earner working groups. And the follow-up study should include the various factors that affect the time allocation of dual-earner groups, such as type of labor and job and children's ages.

• Journal of Trauma and Injury
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• v.32 no.3
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• pp.168-171
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• 2019

The treatment outcome remains poor of severe facial injuries because of the high risk of compromised airway or massive bleeding. We experienced two successful treatment cases of severe facial injury by the chainsaw. A 52-year-male had his face injured by the chainsaw during his work. He was transferred to the Level I trauma center using the Doctor-Helicopter. During his flight, bleeding control was tried and the information was given to the trauma surgeons before his arrival. His consciousness was alert and the vital signs were stable. The crushing wound, mandible open fracture, deep laceration of tongue, lip, neck and arterial bleeding were noted around his mandible. Nasotracheal intubation was performed under the bronchoscope-guided. Emergency operation (open reduction & internal fixation, primary repair with neurorrhaphy) was performed. At 30 hospital days, he was discharged with facial palsy on left mandibular area. A 30-year-male had his face injured by the chainsaw. He was transferred to our Level I trauma center from the local hospital. The deep-mutiple lacerations on right upper eyelid and forehead with the bony exposure were noted. The vital signs were stable and emergency operation was performed. He was discharged at 20 hospital days. Bone loss or tissue loss were not devastating than we expected even though the injury was occurred by the chainsaw. Aggressive treatment including airway manipulation or bleeding control and maximal opportunity of therapy are absolutely needed.