• Annals of Clinical Neurophysiology
• /
• 제2권2호
• /
• pp.95-100
• /
• 2000

Purpose : Primary writing tremor(PWT) can be classified as either type A or type B depending on whether tremor appeared during writing or whilst writing and also on adopting the hand postures normally used for writing. Through the clinical experience author has had an impression that PWT type B may not be purely dependant on specific writing postures. The objective of this study was to clarify whether PWT type B have writing posture-specificity or not. Results : The data indicated that type B PWT is not writing posture-specific. Various pronation and supination postures could evoke tremor as well as writing postures. Furthermore most of other pronation- and supination-related tasks could evoke tremors as well as action of writing. Conclusions : The present data suggest that PWT should be limited only on the pure form of task-spesific PWT type A.

• 대한임베디드공학회논문지
• /
• 제4권4호
• /
• pp.156-163
• /
• 2009

Recently a standard software platform for automotive, AUTOSAR, has been developed to manage growing software complexity and improve software reuseability. However reuse of testing system and test data are difficult because they are dependant on implementation language and testing phases. In this paper, we suggest a automated testing approach for AUTOSAR software component using a standardized testing language, TTCN-3. AUTOSAR defines the AUTOSAR XML Schema for the data exchange format so that it is possible to automatically convert AUTOSAR model into TTCN-3 testing model. Therefore our approach is to present generation techniques for the TTCN-3 testing system from a AUTOSAR XML description. With the proposed testing techniques we can reduce time and effort to build the testing system and reuse testing environment.

• 한국병원경영학회지
• /
• 제25권4호
• /
• pp.48-59
• /
• 2020

Purposes: The purposes of this study is analysis of business performance in national university hospitals in Korea. Methodology: Data from 2010 to 2019 were collected from balance sheet, income statement, and annual reports in 11 national university hospitals. The dependant variables are business performance which are operating margin to total assets, operating margin to gross revenue, and net income to gross revenue. The independent variables are the number of bed, hospital location, opening, liquidity, stability, and activity. Findings: In recent years, activity has been shown to have a lot of influence on management performance. National university hospitals increase profitability by using resources as efficiently as possible. The short-term debt and fixed assets have been increased rapidly in recent years. It was found that management performance has been increased through active investment using financial leverage. Practical Implications: Based on these results, this study will be the basic data for efficient management of national university hospitals.

• 한국전기전자재료학회논문지
• /
• 제18권5호
• /
• pp.484-489
• /
• 2005

Because of its effectiveness for the PD(Partial Discharge) pattern recognition, PSA(Pulse Sequence Analysis) has been considered as a new analytic method instead of conventional PRPDA(Phase Resolved Partial Discharge Analysis). However, it is generally thought that PSA has some possibility to misjudge patterns in case of data-missing resulting from poor sensitivity because it analyses the correlation between sequential pulses, which leads to hesitate to apply it to on-site. Therefore, in this paper, the problems of PSA such as data-missing and noise-adding cases were investigated. for the purpose, PD data obtained from various defects including noise-adding data were used and analyzed. As a result, it was shown that both cases could cause fatal errors in recognizing PD patterns. In case of the data missing, the error was dependant on the kinds of defect and the degree of degradation Also, it could be noticed that the error due to adding noises was larger than that due to some data missing.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권5호
• /
• pp.2287-2290
• /
• 2014

Background: In the past few years, a considerable number of preclinical studies have been proposed metformin as a potential anticancer agent, but some of these studies suffer from a number of methodological limitations such as assessment of cytotoxicity in the presence of supraphysiological glucose concentrations or applying suprapharmacological levels of the drug. These objections have limited the translation of published preclinical data to the clinical setting. The present study aimed to investigate direct anticancer effects of metformin on different molecular subtypes of breast cancer with pharmacological concentrations and under normoglycemic conditions in vitro. Materials and Methods: Breast cancer cell lines from luminal A, luminal B, ErbB2 and triple-negative molecular subtypes were treated with a pharmacological concentration of metformin (2mM) at a glucose concentration of 5.5mM. Time-dependant cell viability was assessed by dye exclusion assay. MTTbased cytotoxicity assays were also performed with metformin alone or in combination with paclitaxel. Results: Metformin did not show any growth inhibitory effects or time-dependant cytotoxicity on breast cancer cell lines in the presence of normal glucose concentrations at the therapeutic plasma level. No augmentation of the antineoplastic properties of paclitaxel was apparent under the tested conditions. Conclusions: Metformin is probably unable to exert cytotoxic or cytostatic effects on breast cancer subtypes at pharmacological concentrations and normal plasma glucose levels. These results highlight the importance of establishing a higher steady-state plasma concentration of metformin in the clinical setting for assessment of anticancer effects in normoglycemic patients.

• International Journal of Oral Biology
• /
• 제34권1호
• /
• pp.37-42
• /
• 2009

The attachment and adhesion of RAW 264.7 and MC3T3-E1 cells to titanium (Ti) discs with various degrees of roughness was investigated. The attachment, adhesion, and proliferation of these cells were evaluated after 4 hr, 24 hr and 7 day incubations. Both RAW 264.7 and MC3T3-E1 cells showed a time-dependant correlation between attachment and adhesion on the surface of the titanium discs. Both types of cells tended to have higher survival rate on these discs as the surface roughness increased. The percentage of adherent inflammatory RAW 264.7 cells was greater than MC3T3-E1 cells at 24 hr, but this was reversed at 7 days in culture. The morphology of osteoblastic MC3T3-E1 cells at 24 hr, determined using a surface emission microscope (SEM), appeared flattened and spread out while inflammatory RAW 264.7 cells were predominantly spherical in shape. The adhesion of both cell types on the titanium discs was dependant on the levels of fibronectin adsorbed on the disc surface, indicating that serum constituents modulate the efficient adhesion of these cells. Our data indicate that the cellular response to the titanium surface is dependent on the types of cells, surface roughness and serum constituents.

• 보건의료산업학회지
• /
• 제10권3호
• /
• pp.13-25
• /
• 2016

Objectives : The purposes of this study was to analyze business performance of university hospitals for the past 10 years. Methods : Management and finance data from 2005 to 2014 were collected from balance sheets, income statements and annual reports from 27 university hospitals. The dependant variable used was profitability which included return on assets, operating margin and net profit to gross revenues 1. The independent variables were general characteristics, liquidity, stability, activity and financial ratios. Results : University hospitals over the last 10 years had achieved good management performance. Using financial leverage, patient revenues, operating profit, nonpatient revenues, total assets and total debt, the total amount had increased by more than double. The ratio of fixed liability and fixed assets turnover was found to have a significant positive (+) effect on management performance in the years 2012-2014. Conclusions : Based on these results, this study suggests a more in-depth analysis using fixed liabilities and fixed assets.

• 한국안전학회지
• /
• 제25권3호
• /
• pp.131-136
• /
• 2010

This study deals with the accident models of arterial link sections by vehicle type. The objectives are to analyze the characteristics of accidents, and to develop the models by type. In pursuing the above, this study uses the data of 414 accidents occurred on 24 major arterial links in 2007. The main results analyzed are as follows. First, the number of accidents is analyzed to account for about 47% in passenger car, 15% in SUV and 10% in trucks. Second, 3 Poisson regression models which are all statistically significant are developed using passenger car, SUV and truck as dependant variables. Finally, AADT and the number of traffic islands as common variables, and the number of pedestrian crossings, lanes, connecting roads, intersections(4-Leg), rate of medians and the number of bus stops as specific variables of the models are selected.

• 한국병원경영학회지
• /
• 제18권3호
• /
• pp.43-61
• /
• 2013

The purpose of this study is to analyze the relations between publicness and profitability of national university hospitals in Korea. Finance and management data from 2008 to 2010 were collected from balancing accounts and annual reports in 13 national university hospitals. The dependant variables are used profitability indicators which are operating margin, net profit to gross revenues, normal profit to gross revenues. The independent variables are publicness indicators which are medical social work, ratio of medical aid in inpatients, ratio of medical aid in outpatients, publicness index. The results show that operating margin, net profit to gross revenues in profitability indicators are affected by medical social work in publicness indicators. Normal profit to gross revenues in profitability indicators is strong related to medical social work and hospital province in publicness indicators. Based on these results, this study suggests implications to balance the publicness and the profitability in national university hospitals.

• 한국건축시공학회:학술대회논문집
• /
• 한국건축시공학회 2011년도 추계 학술논문 발표대회
• /
• pp.69-70
• /
• 2011

During the financial crisis in the late 1990s, we witnessed the large corporations failing at one moment. It is clear that the debt-dependant size augmentation and duplicate investment, and the failure in fund liquidity adjustment were the greatest causes rather than the long-term strategic advantage. Such fact, however, has led to the introduction of advanced financial techniques and security/management of fund liquidity. In order to propose a method to secure fund liquidity at the construction level, this study considers the documentational/precedent studies on project financing among fund procurement methods. And the fund liquidity status at construction level is investigated domestically/internationally to analyze the fund flow. Finally, the actual data is used to analyze progress rate and sales rate to end with the proposal of the method to secure fund liquidity in the progression of this study.