• Title/Summary/Keyword: data obesity

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A Brief Review of Preclinical Researches and Clinical Trials of Oxytocin on Behavior-Related Phenotypes in Prader-Willi Syndrome

  • Kim, Jiyeon
    • Journal of mucopolysaccharidosis and rare diseases
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    • v.5 no.1
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    • pp.39-41
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    • 2021
  • Prader-Willi syndrome (PWS) is a rare genetic neurodevelopmental disorder of hyperphagia leading to severe obesity, intellectual deficits, compulsivity, and other behavioral problems. PWS is caused by the inactivation of contiguous genes on chromosome 15q11-q13, which complicates the development of targeted, effective therapeutics. Various preclinical studies have been conducted by developing mouse models that exhibit phenotypes similar to PWS. Oxytocin deficiency in PWS is associated with hyperphagia with impaired satiety and, food-seeking and behavior disorders. Here, we summarize the oxytocin study of ingestion behavior tested in the PWS mouse model and published data from clinical trials that have evaluated treatment effectiveness on ingestion behavior and social dysfunction in patients with PWS.

Decision tree based obesity and metabolic syndrome data classification and feature importance analysis (의사결정나무 기반 비만과 대사증후군 데이터 분류와 특징 중요도 분석)

  • Lee, Jongwook;Kim, Youngho;Baek, Byunghyun;Hwang, Doosung
    • Proceedings of the Korea Information Processing Society Conference
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    • 2021.11a
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    • pp.880-883
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    • 2021
  • 비만은 다양한 합병증을 일으키는 위험요소로 현대인의 건강을 위협한다. 비만에 영향을 주는 요소들은 유전적 영향, 식습관, 신체활동 등이 연관된다. 비만 인구의 증가로 대사증후군의 발병률이 높아졌다. 대사증후군은 비만, 고지혈증과 고혈압 등의 여러 가지 성인병을 동반한다. 비만과 대사증후군 판별 요소 검출을 위한 개인의 신체 정보와 생활 정보 분석이 필요하다. 본 논문에서는 의사결정나무를 이용하여 비만과 대사증후군을 분류하고 분류 시 사용된 특징의 중요도 분석을 수행한다. 비만 분석 결과는 체중과 신장이 높은 특징 중요도를 나타냈으며 대사증후군은 HDL, 허리둘레, 혈압과 나이 등이 높은 특징 중요도를 보였다.

Comparison of the Results of Clinical Diagnostic Assay according to Sasang Constitution Classification (사상체질에 따른 임상적 진단검사 결과 비교)

  • Park, Jee-Won
    • Korean Journal of Adult Nursing
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    • v.15 no.2
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    • pp.215-225
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    • 2003
  • Purpose: Sasang constitutional medicine is Korea's creative medical science, that has attracted public attention. But for lack of indices in objectifying constitutions, there are difficulties for most of health professionals in approaching Sasang medicine. The purpose of this study was to compare the results of clinical diagnostic data according to the type of Sasang constitution. Method: The subjects were 195 examinees who had a general health check-up at A hospital. The instrument used for this study were Questionnaire of Sasang Constitution Class II(QSCCII) program for personal computer developed by Kim Sun Ho et al. Result: The distribution of constitutions of the subjects were the So-eum 46.7%, the Tae-eum 36.9% and the So-yang 16.4%. The level of body compositionrelated indices(body weight, obesity) of the Tae-eum were significantly higher than those of other constitutions. In heart-related indices, systolic BP were the highest in the Tae-eum. In liver-related indices, the level of triglyceride, SGPT were significantly higher in the Tae-eum. But the hematologic indices and lung-related indices were not showed significantly difference among any constitutions. Conclusion: The results of this study showed that there were significant difference of clinical diagnostic data according to Sasang constitutions, especially in the Tae-eum. So, to understand the human nature of nursing clients, nurses need to apply the oriental based medical theory, like Sasang constitution, to the discipline of nursing.

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The Effects of Weight Control Program on Body Composition, Blood Pressure, Serum Lipid and Self-Regulation Behavior in Obese College Women (비만중재프로그램이 비만 여대생의 신체구성, 혈압, 혈중지질 및 자기조절행위에 미치는 효과)

  • Kim, Kyung Hae;Chung, Bok Yae;Byun, Hye Sun
    • Korean Journal of Adult Nursing
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    • v.19 no.3
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    • pp.339-352
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    • 2007
  • Purpose: The purpose of this study was to investigate the effect of weight control program on body composition(body mass index and waist-hip ratio), blood pressure, serum lipids(total cholesterol, triglyceride, high density lipoprotein and low density lipoprotein) and self-regulation behavior in obese college women. Methods: Forty seven obese subjects were divided into experimental(22) and control(25) groups. The weight control program lasting 12 weeks consisted of a traffic-light diet, jumping-rope exercises, and behavior modification methods with e-mail counseling. The data were collected from 29 March to 17 September of 2004. The variables were assessed before and after intervention for 12 weeks in two groups. Then, those were repeated after a 12 week suspension of intervention in the experimental group. The data were analysed by the SPSS computer program. Results: BMI, HDL, LDL and self-regulation behavior levels showed significant differences between the experimental and control groups. While there were no significant differences in waist-hip ratio, blood pressure, total cholesterol and triglyceride. Conclusion: The weight control program had a positive effect on obese college women, and can be used to control obesity.

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Nutritional Assessment of the Oldest-Old Population Aged 85 Over: Based on 2009 Korea National Health and Nutrition Examination Survey

  • Bak, Hoonji;No, Jae-Kyung
    • Culinary science and hospitality research
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    • v.22 no.1
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    • pp.52-60
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    • 2016
  • As Korea is expected to become super high aged society in 2026, nutrition is important elements of health in the elderly and affects their life. In epidemiological surveys, anthropometric and biochemical measurements represent important components of nutritional assessment in elderly. In the present study, we investigated anthropometric index, biochemical markers, and nutrient intake for elderly aged over 85 by using data on 71 elderly (24 men, 47 women) over 85 years which was obtained from Korea National Health and Nutrition Examination Survey in 2009. According to BMI values, the prevalence of underweight and obesity was 9.7% and 34.5% in men, and 7.9% and 26.4% in women. The prevalence of sarcopenia was 70.7% in men and 25.0% in women. However, plasma biochemical data are normal range in the older population. In nutrients intake, daily Intake of energy, protein, dietary fiber, water, thiamin, riboflavin, niacin, calcium, and potassium was inadequate considering the Dietary Reference Intakes for Koreans(KDRIs). In conclusion, elderly need to be educated nutrition and their health dietary life to prevent malnutrition, and standard of nutrition intake should be rearranged in elderly aged 85 over considering their antrhopometric index.

Prevalence of Chronic Diseases according to Health Behavior of Manufacturing Workers (제조업 근로자의 건강행태에 따른 만성질환 유병률)

  • Kim, Jung-Young;Lee, Eun-Ju;Suh, Soon-Rim
    • The Korean Journal of Health Service Management
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    • v.11 no.1
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    • pp.107-115
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    • 2017
  • Objectives : The purpose of this study was to examine the relationship between the health behavior and prevalence of chronic diseases among manufacturing workers. It would provide fundamental data in the development of health promotion programs for manufacturing workers. Methods : Data on 3,171 employees who underwent health check-ups by the National Health Insurance Service in L company, G City from March to December 2014 were analyzed. The statistical analysis of frequency, chi-square test, and multiple logistic regressions were performed using SPSS 18 program. Results : The results of this study show that obesity and over-weight are the health behaviors that influence the prevalence of chronic diseases in manufacturing employees. Conclusions : The implementation of public health projects to improve the voluntary participation of the employees can enhance their health, improve the productivity, and influence their quality of life positively by changing the health behaviors.

Impact of Lifestyle and Health Examination Results on Sick Leave in Commercial Airline Pilots (운항승무원의 생활습관과 건강검진 결과가 병가에 미치는 영향)

  • Kim, Jiseon;Lee, Nam-Ju
    • Korean Journal of Occupational Health Nursing
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    • v.29 no.3
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    • pp.184-191
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    • 2020
  • Purpose: This study aims to compare the general characteristics, life-style, health examination results, and sick leave days by airmen medical examination decision and to investigate factors affecting sick leave days. Methods: We obtained data from 2,361 Korean pilots who worked for a commercial airline. Comparison of the results by airmen medical examination decision (Fit or waver) was conducted using the 𝝌2 test or Fisher's exact test. Factors affecting sick leave days were analyzed using logistic regression. Results: Age, smoking history, blood pressure, obesity, and fasting blood sugar level were significantly different between the Fit and Waver groups. Rate of using sick leave long-term was higher in the Waver than in the Fit. Sick leave days were significantly associated with age, habits of drinking, and smoking in the Fit group. Conclusion: This study demonstrated the health risk factors that affect the number of sick leave days. By providing basic data for the health care of workers, it is expected to be applicable to the provision of health promotion and disease prevention programs for workers.

Comparison of Elementary Students' Health Behaviors by Geographical Regions (우리나라 초등학생들의 지역별 건강생활실천 비교)

  • Lee, Jung-Yul;Lee, Kyu-Yung;Houng, Yun-Mi
    • Korean Journal of Health Education and Promotion
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    • v.24 no.4
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    • pp.87-98
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    • 2007
  • Background: Health promotion services should be provided based on clients' health promotion needs. To provide health promotion services for elementary students in Korea, health promotion needs by geographical regions should be analyzed. Purpose: To analyze elementary students' health behaviors by regions. Method: Elementary students of 4018 from large cities, 1636 from medium sized cities, 328 from rural areas were included. Data collection was done using items from National Health and Nutrition Survey and was collected by mail from schools. For data analysis, Chi-square test and multiple logistic regression were utilized. Result: From comparison of health behaviors, there were no significant differences between large cities and medium sized cities. However, there were significant differences between urban students and rural students in terms of fast food intake, breakfast, soft drink intake, sleeping hours, tooth brush, and obesity. Conclusion: Health promotion services, especially correcting unhealthy eating behaviors for rural elementary students should be focused.

Development of All-in-One Pattern Specialized for Obesity in Old Age

  • Yun, Jeong;Na, Mi-Hyang
    • Fashion & Textile Research Journal
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    • v.21 no.6
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    • pp.830-836
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    • 2019
  • A diverse range of products are currently being sold; however, it is very difficult to purchase All-in-One patterns that reflect the body types of the elderly stage in the open market. This study is to develop specialized All-in-One patterns by assessing obese body types characteristics of the elderly social class. Five healthy women with typical obese body types in the elderly stage with busts, waists, and hips surpassing 100 cm were chose as test subjects. The three subjects for the wearing experiment are those with more than one year of experience wearing a bodysuit. A self-evaluation was made three times by looking in the mirror. The data from this study was processed to find averages and deviations; in addition, and a t-test was performed using the SPSS 24 statistical software. A total of 13 body parts were measured prior to and while wearing the specialized All-in-One patterns. Significant results were obtained from all 12 items. All-in-One for research appears to have produced a high level of satisfaction for subjects. This study can provide basic data on elevating the levels of satisfaction of the consumers in their elderly stages with special body types that deviate from standard body types at the time of wearing garments as well as for inner-wear companies to graft this market as a high-value-added niche market.

Food Insecurity and Related Risk Factors in the Elderly: Korea National Health and Nutrition Examination Survey 2013 Data (우리나라 노인의 식품불안정성 및 관련 요인: 2013년 국민건강영양조사자료)

  • Lee, Hye-Sang
    • Journal of the Korean Dietetic Association
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    • v.21 no.4
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    • pp.308-319
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    • 2015
  • The purpose of this study was to assess risk factors associated with food insecurity in the Korean elderly aged over 65 years using data from the Korea National Health & Nutrition Examination Survey 2013 (KNHANES VI). A total of 1,200 subjects were analyzed among the participants of the KNHANES 2013 by using SPSS statistics complex samples (ver. 21.0). Food insecurity was measured by using the modified US Household Food Security/Hunger Survey Module. Thirteen percent of subjects lived in food insecure households. There were differences in the prevalence of food insecurity according to sex, educational level, income level, and household structure. Mean age of the food insecurity group was significantly higher than that of the food security group. The results of logistic regression analysis showed that food insecurity was significantly associated with alcohol intake (OR: 1.82), prevalence of melancholy (OR: 2.07) and suicidal thoughts (OR: 2.67), and intake deficiency of energy (OR: 1.60), calcium (OR: 1.97), iron (OR: 1.97), potassium (OR: 1.96), riboflavin (OR: 1.76), and niacin (OR: 1.64), while not with smoking, physical activity, chronic diseases including obesity, anemia, diabetes, and osteoarthritis, and deficiency of protein, vitamin A, thiamin and vitamin C. These findings suggest that food insecurity is strongly related to mental health and certain nutrient intakes. Prospective research is needed to establish the effects of food insecurity on chronic diseases.