• 대한지역사회영양학회지
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• 제26권5호
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• pp.363-381
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• 2021

Objectives: This study examined the Korean elderly's dietary intake status, subjective health-related perception and chronic disease prevalence among age groups. Associations of dietary quality with subjective health-related perception and chronic diseases were also examined. Methods: Based on data from the 7th National Health and Nutrition Examination Survey, a total of 3,231 elderly were selected and categorized into 4 age groups of '65 ~ 69', '70 ~ 74', '75 ~ 79' and 'over 80'. Nutrient intakes, proportions of those with insufficient nutrient intakes, Korean Healthy Eating Index (KHEI), some subjective health-related perceptions and prevalence of major chronic diseases were compared according to the age groups. Differences in the subjective health-related perceptions and odds ratios of the chronic diseases according to the quartile levels of KHEI within the same age group were analyzed. Results: With the increase of age, several nutrient intakes (P < 0.001) and KHEI scores significantly decreased (P < 0.01). In women, activity restriction increased (P < 0.05), and EQ-5D score decreased with age (P < 0.001). Prevalence of hypertension (P < 0.0001), hypercholesterolemia (P < 0.05) and anemia (P < 0.01) significantly increased, while hypertriglyceridemia (P < 0.01) significantly decreased only in men. Obesity prevalence decreased, while underweight prevalence increased (P < 0.05). Subjective health status, EQ-5D score and PHQ-9 score significantly improved as KHEI score increased in certain age groups of women (P < 0.05). Odds ratio of hypercholesterolemia significantly increased with the increase of KHEI score in 65 ~ 69-year-old women. However, hypertension and anemia significantly decreased with the increase of KHEI score in 75 ~ 79-year-old women (P < 0.05). Conclusions: The study findings suggest that nutrition management and policy for the Korean elderly need to apply a segmented age standard that can better reflect their dynamic characteristics.

• 한국융합학회논문지
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• 제12권3호
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• pp.317-323
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• 2021

본 연구의 목적은 청소년의 체질량지수에 따른 구강증상 경험을 분석하고자 함이다. 청소년건강행태조사 자료를 이용하여 총 55,728명을 대상으로 복합표본분석을 실시하였다. 민감성 치아, 치아통증, 치은출혈 및 부종의 경험은 각각 과체중 그룹(36.8%, 23.9%, 19.2%)에서 가장 높고 저체중 그룹(34.6%, 20.8%, 17.0%)은 가장 낮았으며, 구취경험은 비만 그룹이 26.7%로 가장 높고 저체중 그룹은 18.8%로 가장 낮았다(p<0.001). 정상체중을 기준으로 했을 때 치아통증 경험은 과체중 그룹이 1.08배(95%CI: 1.01-1.15) 유의하게 높았고 치은출혈 및 부종 또한 과체중 그룹에서 1.08배(95%CI: 1.01-1.16) 유의하게 높았다. 구취경험은 과체중 그룹에서 1.19배(95%CI: 1.11-1.27), 비만 그룹에서 1.43배(95%CI:1.35-1.52) 유의하게 높았다. 차후 전신건강과 구강건강에 관한 보다 다양한 연구가 필요할 것이다.

• Journal of Korean Biological Nursing Science
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• 제23권1호
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• pp.31-42
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• 2021

Purpose: This study was performed to assess the level of blood glucose and to identify poor glycemic control groups among patients with type 2 diabetes mellitus (DM). Methods: Data of 1,022 Korean type 2 DM patients aged 30-64 years were extracted from the Korea National Health and Nutrition Examination Survey VII. Complex samples analysis and a decision-tree analysis were performed using the SPSS WIN 26.0 program. Results: The mean level of hemoglobin A1c (HbA1c) was 7.22±0.25%, and 69.0% of the participants showed abnormal glycemic control (HbA1c≥6.5%). The characteristics of participants associated with poor glycemic control groups were presented with six different pathways by the decision-tree analysis. Poor glycemic control groups were classified according to the patients' characteristics such as period after DM diagnosis, awareness of DM, sleep duration, gender, alcohol drinking, occupation, income status, low density lipoprotein-cholesterol, abdominal obesity, and number of walking days per week. Period of DM diagnosis with a cut-off point of 6 years was the most significant predictor of the poor glycemic control group. Conclusion: The findings showed the predictable characteristics of the poor glycemic control groups, and they can be used to screen the poor glycemic control groups among adults with type 2 DM.

• 디지털융복합연구
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• 제19권3호
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• pp.371-378
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• 2021

본 연구의 목적은 클로로겐산이 함유된 피부 패치를 피부에 부착하여 체지방과 체중에 미치는 변화를 규명하여, 유용성을 평가하는 것이다. 시험군 8명, 대조군 8명으로 총 16명의 대상자가 연구에 참여하였고, 연구 기간은 2020년 08월 03일부터 2020년 08월 31일까지 4주간 실시하였다. 군-간 효과검정 결과 체지방의 변화는 전체적으로 유의한 차이가 없었으나(F=4.38, p<.055), 1주 후와 4주 후 검사에서는 의미있는 변화(p<.001)가 있었다. 또한, 체중은 유의미한 차이로 시험군이 대조군보다 체중 감소가 큰 것으로 나타났다(F=9.43, p<.008). 이번 연구의 결과는 비만 관련 연구에 패치를 적용한 예비연구로써 의미가 있다고 할 수 있으며, 연구의 결과가 향후 연구될 피부 패치 연구의 기초 자료로 활용될 수 있을 것으로 판단된다.

• 동의생리병리학회지
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• 제35권1호
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• pp.36-41
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• 2021

Many prior studies on neck pain after a traffic accident (TA), but there is a lack of research on risk factors for post-TA neck pain in Korea. The purpose of this study was to examine the relationship between post-traffic neck pain and the demographic characteristics of TA patients and to find any factors affecting the neck pain after TA. In this study, 120 TA patients in a Korean medicine hosipital were analysized. The Korean version of the Neck disability Index (NDI) and Numeral Rating Scale (NRS) were used. Data were summarized by frequency(%) and mean(standard deviation). Pearson correlation test, Independent sample t-test, chi-squre test, one-way ANOVA and two-way ANOVA were performed. The IBM SPSS Advanced Statistics for window, version 20.0 was used for statistical processing. All p-values less than 0.05 were considered statistically significant. NDI and NRS were highly correlated. NRS and NDI showed higher scores for women, those in 30s, BMI≥25, and side collisions, but there were no statistically significant differences. For women, the direction of collision was observed to affect NDI. In this study, it was confirmed that the NDI and NRS had a high correlation. However, it was confirmed that sex, degree of obesity, direction of traffic accident collision are not factors that significantly affect the intensity of neck pain and the functional disorder by neck. It is necessary to conduct an additional study by larger scale.

• 한국식생활문화학회지
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• 제37권5호
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• pp.438-445
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• 2022

Laminaria japonica is a type of brown algae widely consumed in Asian countries and contains many essential nutrients and exhibits anti-obesity, antioxidant, and anti-inflammatory effects. In this study, the antioxidant and immunomodulatory effects of a Laminaria japonica water extract (LJE) were investigated using an in vitro model. Mean total polyphenol content of LJE was 2.16±0.11 ㎍ GAE/mg, and LJE dose-dependently inhibited ABTS radical activity but did not scavenge DPPH radicals. In addition, LJE enhanced nitric oxide (NO) production and upregulated the mRNA expressions of proinflammatory cytokines (i.e., tumor necrosis factor-α and interleukin-6) in RAW 264.7 cells. On the other hand, LJE inhibited NO production and downregulated proinflammatory cytokine mRNA levels in endotoxin-stimulated RAW 264.7 cells. Thus, our data show that LJE has moderate antioxidant activity and biphasic immunomodulatory effects on RAW 264.7 cells. In summary, the study indicates that LJE has potential therapeutic use as a novel biphasic immuno-modulator.

• Journal of Interdisciplinary Genomics
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• 제4권2호
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• pp.35-38
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• 2022

Background: Prader-Willi syndrome (PWS) is a complex genetic disease associated with growth impairment, severe obesity and metabolic dysfunctions. High proportion of PWS patients are born small for gestational age (SGA) than normal children, which also increase the risk of growth impairment and metabolic dysfunction in PWS. We aimed to compare growth outcome and metabolic profiles between SGA and appropriate for gestational age (AGA) PWS patients. Methods: Data of 55 PWS children and adults aged more than 2 years old (32 male and 23 female, age 2-18.8 years) from single center were studied. Only patients who were treated with GH were included. The clinical characteristics and laboratory findings were reviewed retrospectively. Results: Among 55 subjects, 39 had 15q11-13 deletion and 16 had uniparental disomy (UPD). Twenty (36.3%) were born SGA. All patients received GH treatment, and 11 (20%) discontinued GH treatment. Mean age at GH treatment initiation was 2.5 (range 0.3-12.4) years, and mean duration of treatment was 6.3 (range 1.0-11.3) years. Current height-SDS (-0.36 vs -0.16) and BMI-SDS (1.44 vs 1.33) did not differ between AGA and SGA group. Two patients in SGA group, but none in AGA group had diabetes mellitus. Mean glucose level was also higher in SGA group (100.1 vs 114.4 mg/dL). Conclusion: Our report gives an overview of growth profile and metabolic dysfunctions recorded in GH treated PWS patients. Growth profile did not differ between AGA and SGA group. Glucose level was higher in SGA group, so more careful monitoring and prevention for DM will be required in SGA group.

• 한국의상디자인학회지
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• 제24권3호
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• pp.127-144
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• 2022

This paper aims to analyze the different external images of women expressed in ancient artwork through the socio-cultural background and the aesthetic view during the Tang and Song dynasties of China. The research method contains a literature review involving the collection of historical literature, thesis, and artwork data. The image of women according to the aesthetic view of the two periods is summarized as follows. In terms of face shape, the Tang pursued a round face while the Song pursued a more slender shape. As for hair ornamentation, the Tang wore various shapes of hair buns like "Paojiaji", and decorated them with coronets. The Song wore various types of braided hair called "Tongxinji", but the coronets were smaller and more sophisticated. For makeup, the Tang wore colorful and heavy makeup and the Song makeup was lighter and more elegant. In attire, the Tang followed revealed shape, used splendid colors and thin, transparent material. The Song exhibited a more simple design and was conservative and neat, using luxurious silk fabric with low chroma. In body shape, the Tang pursued the "beauty of obesity" with a voluptuous body shape; the Song pursued the "beauty of gaunt" with a slim body shape. As the result of the analysis according to the aesthetic views of the Tang and Song dynasties, women of Tang were depicted as rich, and women of Song were rather neat. The research on the aesthetic views that changed according to the development of social civilization and the status of women will play an active role in the transmission and development of traditional Chinese culture. At this point, the paper may contribute to the creation of images of women as well as changes in the art of future generations.

• Tuberculosis and Respiratory Diseases
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• 제85권4호
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• pp.349-357
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• 2022

Background: The most consistently identified mortality determinants for the new coronavirus 2019 (COVID-19) infection are aging, male sex, cardiovascular/respiratory diseases, and cancer. They were determined from heterogeneous cohorts that included patients with different disease severity and previous conditions. The main goal of this study was to determine if activities of daily living (ADL) dependence measured by Barthel's index could be a predictor for COVID-19 mortality. Methods: A prospective cohort study was performed with a consecutive sample of 340 COVID-19 patients representing patients from all over the northern region of Portugal from October 2020 to March 2021. Mortality risk factors were determined after controlling for demographics, ADL dependence, admission time, comorbidities, clinical manifestations, and delay-time for diagnosis. Central tendency measures were used to analyze continuous variables and absolute numbers (proportions) for categorical variables. For univariable analysis, we used t test, chi-square test, or Fisher exact test as appropriate (α=0.05). Multivariable analysis was performed using logistic regression. IBM SPSS version 27 statistical software was used for data analysis. Results: The cohort included 340 patients (55.3% females) with a mean age of 80.6±11.0 years. The mortality rate was 19.7%. Univariate analysis revealed that aging, ADL dependence, pneumonia, and dementia were associated with mortality and that dyslipidemia and obesity were associated with survival. In multivariable analysis, dyslipidemia (odds ratio [OR], 0.35; 95% confidence interval [CI], 0.17-0.71) was independently associated with survival. Age ≥86 years (pooled OR, 2.239; 95% CI, 1.100-4.559), pneumonia (pooled OR, 3.00; 95% CI, 1.362-6.606), and ADL dependence (pooled OR, 6.296; 95% CI, 1.795-22.088) were significantly related to mortality (receiver operating characteristic area under the curve, 82.1%; p<0.001). Conclusion: ADL dependence, aging, and pneumonia are three main predictors for COVID-19 mortality in an elderly population.

• 한국융합학회논문지
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• 제12권5호
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• pp.255-266
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• 2021

본 연구는 건강증진모형을 이론적기틀로 하여 역류성 식도염 환자의 건강증진행위 및 이에 대한 영향요인을 파악하기 위한 서술적조사연구이다. C 대학병원 소화기내과 외래 환자 중 역류성식도염 진단을 받은 178명을 대상으로 설문조사를 실시하였다. SPSS WIN ver 20.0을 이용하여 기술통계, t-test, ANOVA, scheffe test, Pearson 상관관계, 다중회귀분석을 이용하여 분석한 결과 역류성 식도염 환자의 음주, BMI, 유익성, 내적통제위, 지각된 건강상태가 건강증진행위에 유의한 영향요인이었고, 설명력은 49%이었다. 본 연구는 재발이 잦은 역류성식도염을 완화시키기 위해서 음주, 식습관, 비만조절 등의 생활습관 변화가 필요하다는 선행연구에 대한 근거를 제시하였으며, 향후 이를 토대로 교육프로그램을 개발 및 적용하여 구체적인 효과평가를 위한 실험연구 수행을 제안한다.