• Title/Summary/Keyword: damaging effect

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Voltammetric Studies of Cu-Adriblastina Complex and its Effect on ssDNA-Adriblastina Interaction at In Situ Mercury Film Electrode

  • D.Abd El Hady;M.Ibrahim Abdel Hamid;M.Mahmoud Sellem;N.Abo E Maali
    • Archives of Pharmacal Research
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    • 제27권11호
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    • pp.1161-1167
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    • 2004
  • Adriblastina, a cancerostatic anthracycline antibiotic, causes considerable oxidative damage to DNA molecules. The interaction of this compound with DNA was investigated using Osteryoung square wave stripping voltammetry (OSWSV) and cyclic voltammetry (CV) at an in situ mercury film electrode. It was found that the equilibrium constant of the bonded oxidized form of the drug was 63 times bigger more important than that of the bonded reduced form. Copper forms 1 metal: 2 drug stoichiometry complex which is highly stable compared to ssDNA-drug interaction and consequently inhibited the drug biochemical damaging effects. Copper complex offered sub-nanogram determination of adriblastina in aqueous and urine media.

농촌의 산림경관 유지를 위한 개선방안 연구 (A Study on forest landscape improvement in rural area)

  • 정욱주
    • 농촌계획
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    • 제15권2호
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    • pp.1-8
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    • 2009
  • The purpose of this study is to find a way to improve damaged forest in rural area in terms of both landscape . quality and regulation. Mountain and forest cover 65% of total land in Korea, and the shortage of areas for developing housing, road and facilities made us to use forest area for above purposes. This led various types of damages on the sensitive rural landscape visually and ecologically. There are rules and regulations for decreasing damaging effect by constructions on forest area, but it was not so effective because theses rules focused on quantitative issues only. This study will consist of three phases, 1. analyse landscape damage types by development tendencies in forest area 2. find diminution plan on each damage types 3. set improvement on rules and regulations both qualitatively and quantitatively. This study will meet the goal of improving and managing rural and forest landscape by providing objective standards, rational procedure and amelioration plan.

농약(農藥) 환경(環境) 안전성(安全性) 평가(評價)의 국제적(國際的)인 조화(調和) (International Harmonisation of Pesticide Environmental Safety Assessments)

  • 디 라일리;제이 다이슨
    • 한국잡초학회지
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    • 제17권1호
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    • pp.73-79
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    • 1997
  • Governments and industry have a growing interest in the harmonization of environmental test methods and risk assessment procedures. OECD are currently producing a set of harmonised test guidelines for studying the environmental fate and ecological effects of pesticides. FAO has published an environmental risk assessment procedure. This procedure, which is similar to those used in US and Europe, is based on calculating the ratio of the toxicity of a pesticide to indicator organisms to their level of exposure to the pesticide. The exposure depends on both the concentration of the pesticide and its bioavailability. Ratios which indicate a pesticide will not produce a harmful effect have been established using ecological field studies. Examples are presented for assessing the risk to aquatic ecosystems, earthworms and honeybees. Long-term field studies(up to 20 years) have also shown that pesticides can be used indefinitely without harming soil fertility. Herbicides can be used to avoid the ecologically damaging effects of using soil cultivations excessively for weed control.

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연성 식생모형에 의한 해빈침식방지 특성에 관한 실험적 연구 (Hydraulic Experiment on the Effects of Beach Erosion Prevention with Flexible Coastal Vegetation)

  • 이성대;박정철;홍창배
    • 한국해양공학회지
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    • 제23권1호
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    • pp.31-37
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    • 2009
  • Coastal vegetation consists of rooted flowering marine plants that provide a variety of ecosystem services to the coastal areas they colonize. The attenuation of currents and waves and sediment stabilization are often listed among these services. From this point of view, artificial seaweed is an effective method of controlling sea bed sediment and stabilization without damaging the landscape or the stability of the coastline. A series of hydraulic experiments were performed in a wave channel with regular and irregular waves to examine the effect of artificial seaweed in relation to scouring and beach erosion prevention. Based on the results of these experiments, the coastal vegetation model is efficient against scouring and beach erosion.

Effects of Neutral, Cationic, and Anionic Chromium Ascorbate Complexes on Isolated Human Mitochondrial and Genomic DNA

  • Ay, Ahmet Nedim;Zumreoglu-Karan, Birgul;Oner, Reyhan;Unaleroglu, Canan;Oner, Cihan
    • BMB Reports
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    • 제36권4호
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    • pp.403-408
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    • 2003
  • The relative activities of neutral, cationic, and anionic chromium ascorbate complexes toward isolated human mitochondrial and genomic DNA were investigated at physiologically relevant conditions by agarose gel electrophoresis. A direct relationship between the charge of the Cr(III) species and their DNA-damaging properties was found. The cationic species were found to be fully capable of DNA-cleavage, even in short incubation periods. Incubations were also performed in the presence of amino acids. No apparent effect was observed under the applied experimental conditions to facilitate or prevent damage through the ternary amino acid-Cr-DNA adduct formation or binary chromium-amino acid complex formation.

점착형 도막.시트 일체형 방수재를 이용한 비노출용 복합 방수공법에 관한 실험적 연구 (An Experimental Study on the Non-Exposure Composite Waterproofing Method used Adhesion Liquid and Sheet Integrate Waterproofing Material)

  • 김진성;선윤숙;박진상;오상근
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2007년도 춘계학술논문 발표대회
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    • pp.125-128
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    • 2007
  • The problem of water leakage due to damaging waterproof in concrete structure, causes the impediment in a long term and shortened the life span of durability. There are a lot of techniques for repair and reinforcement to improve using environment. However, the improper construction which is unconsidered various environmental conditions, could effect to increase the maintenance expenses. Therefore, this study will be compared and estimated the adhesion liquid and sheet integrate waterproofing material, as analyzing the existing problem. For those result, we would like to arrange the alterative plan for the long durability and user needs of concrete structure.

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비섬유소 인조 섬유의 일광 안정도 증진에 관한 연구 (A Study on the Light Stability Increasement of Non-Cellulosic Fiber)

  • 육영수;안태완
    • 기술사
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    • 제9권1호
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    • pp.35-39
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    • 1976
  • Possible methods of protection of non cellulosic fibers, particularly nylon filament yarn, from the damaging effects of light are discussed. Manganese acetate, cupricacetate, G1-06-196 and sodium phosphate are used as a light stabilizer for nylon filament yarn. The light stability of filament containing different weight of TiO$_2$ is increased as the following order: Bright>Semi-Dull>Full-Dull The protection effect against light according to the present of the light stabilizer in filament increased in the following order: Manganese acetate> Cupric acid> G1-06-196> Sodium phosphate Manganese acetate is shown to be the most effecting salt for protecting nylon against light. 15 ppm of the salt is shown to be effective enough for protecting nylon filament yarn against light.

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Investigating delay factors in construction industry: A Korean perspective

  • Acharya, Nirmal Kumar;Im, Hae-Man;Lee, Young-Dai
    • 한국건설관리학회논문집
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    • 제7권5호
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    • pp.177-190
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    • 2006
  • Construction projects are facing delay problems. Delays in construction have been immense effect on performance or satisfactory delivery of the project. Delays have been causing project cost overrun as well as it is a source of dispute hence damaging the relationship between the project participants. The purpose of this study was to explore the causes of delay risk through a field survey study. Data were collected from construction professionals working in owner, consultant and contractor organizations. All together 208 questionnaire instruments were used and analyzed by employing statistical tools (SPSS computer program). 19 delay factors were identified by this study, out of which following factors were critical: Frequent interruptions from public (local people, pressure group etc.), changed site condition, failure to provide required construction site, unrealistic project time estimation and design errors.

Numerical modelling of the damaging behaviour of the reinforced concrete structures by multi-layers beams elements

  • Mourad, Khebizi;mohamed, Guenfoud
    • Computers and Concrete
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    • 제15권4호
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    • pp.547-562
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    • 2015
  • A two-dimensional multi-layered finite elements modeling of reinforced concrete structures at non-linear behaviour under monotonic and cyclical loading is presented. The non-linearity material is characterized by several phenomena such as: the physical non-linearity of the concrete and steels materials, the behaviour of cracked concrete and the interaction effect between materials represented by the post-cracking filled. These parameters are taken into consideration in this paper to examine the response of the reinforced concrete structures at the non-linear behaviour. Four examples of application are presented. The numerical results obtained, are in a very good agreement with available experimental data and other numerical models of the literature.

Control Effect on Root-knot Nematodes by Hot Water Dipping Treatment in Kiwifruit

  • Ma, K.;Cho, Y.;Jeong, B.;Choi, D.
    • 한국유기농업학회지
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    • 제19권spc호
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    • pp.255-258
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    • 2011
  • When kiwifruit root system infected with nematodes was treated by hot water dipping treatment, the maximum temperature for this treatment was suggested as $50^{\circ}C$. The lowest killing temperature of internal root-knot in the root tissue was $48^{\circ}C$. Consequently, root-knot nematodes could be killed without damaging root tissues by the hot water dipping treatment at $48^{\circ}C$ for 10 minutes. This could be useful for organic production and distribution of kiwifruit seedlings by avoiding the synthetic nematicides which are not easily decomposed in soil once applied.