• The Journal of the Convergence on Culture Technology
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• v.9 no.1
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• pp.685-690
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• 2023

It was analyzed that the volume of deep excavation works adjacent to existing underground structures is increasing according to the population growth and density of cities. Currently, many underground structures and tracks are damaged by external factors, and the cause is analyzed based on the measurement results in the tunnel, and measurements are being made for post-processing, not for prevention. The purpose of this study is to analyze the effect on the deformation of the structure due to the excavation work adjacent to the urban railway track in use. In addition, the safety of structures is evaluated through machine learning techniques for displacement of structures before damage and destruction of underground structures and tracks due to external factors. As a result of the analysis, it was analyzed that the model suitable for predicting the structure management standard value time in the analyzed dataset was a polynomial regression machine. Since it may be limited to the data applied in this study, future research is needed to increase the diversity of structural conditions and the amount of data.

• Journal of Navigation and Port Research
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• v.47 no.1
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• pp.37-48
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• 2023

Recently, the increase of international trade volume is leading to risk exposure and safety accidents in the port terminal industry. In addition, as Serious Disaster Punishment Act came into effect on January, 2021, various guidelines and laws to protect safety and life in port terminals are being enacted. However, despite these efforts, medium-to-large safety accidents in the port terminal industry have occurred. According to the Korea Occupational Safety and Health Agency, from 2016 to 2019, the number of casualties in the port handling industry increased by 4.2%. To build some effective follow-up management of port accidents and preparation of related safety laws/systems, a risk analysis in consideration of causes and damage of accidents should be conducted. Therefore, in this study, major risk factors and preventive measures were derived by conducting risk assessment based on 1,039 cases of port terminal accidents collected by the Korea Occupational Safety and Health Agency for five years. Priorities for preventive measures were then determined through IPA analysis, Borich needs analysis, and The Locus For Focus analysis.

• Journal of the Korean GEO-environmental Society
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• v.24 no.4
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• pp.5-11
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• 2023

Impulse waves generated by landslides near water bodies can lead to fatal damage to human life and surrounding infrastructure. These impulse waves are generally called landslide-impulsed waves and occur without being limited to a specific area. Recently, localized torrential rains have frequently occurred due to the influence of abnormal weather, both the frequency and scale of landslides occurring in Korea are increasing. Therefore, in this study, the experiments were conducted according to the mass ratio of the landslide models, and among the characteristics of the generated landslide-impulse waves. And the wave amplitude was observed and analyzed. In this study, a total of 75 experiments were conducted by repeating the experiment 5 times for 15 cases with mass ratios of 5 landslide models and 3 types of slope angles. As a result of experiments with different mass ratios of landslide models, if the landslides have the same initial energy, the size of the landslide-impulse waves generated by mixing granular and block forms is higher than the size of the landslide-impulse waves generated by pure granular and block landslides. It is analyzed that the size may be larger.

• Conservation Science in Museum
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• v.29
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• pp.99-110
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• 2023

The stone fragments that are missing from the stone cultural heritage have limited use beyond being directly fitted to identify their original position, as they are relatively heavy and bulky, and there is the further risk of secondary physical damage during manual work. Therefore, in this study, morphological relationships between the missing parts and the stone fragments were identified through digital restoration, and a three-dimensional (3D) printed replica was created for use at the exhibition for Stone Buddhas in Four Directions in Hwajeon-ri, Yesan, where 72 stone fragments had been excavated together. First, for the digital restoration, stone fragments of similar shapes were selected after the coordinates of the 3D scanning model were aligned in virtual space. In addition, the stone fragments were printed using a 3D printer to check whether they were physically related to the missing parts. Thus, the original positions of a total of nine stone fragments were identified. To utilize these research results in the exhibition, a 1:1 replica of the Stone Buddhas in Four Directions was produced using 3D printing technology, and the nine stone fragments were also restored to their original positions. The digital technology used in this study is of great importance in that it not only made up for the limitations of the direct manual method but also suggested the possibility of expanding its application to the fields of documentation, restoration, and replication of similar cultural heritage.

• Nuclear Engineering and Technology
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• v.55 no.4
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• pp.1460-1467
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• 2023

A robust approach was conducted to determining the absolute oral bioavailable (f_ab) fractions of ²³⁸U and ²³²Th in rats exposed to contaminated soil along with their hematotoxicity and nephrotoxicity. The soil sample is the International Atomic Energy Agency-312 (IAEA-312) certified reference material, whereas blood, bones, and kidneys of in vivo female Sprague-Dawley (SD) rats estimate ²³⁸U- and ²³²Th-f_ab fractions post-exposure. We predict the bioavailable concentration (C_ab) and f_ab values of ²³⁸U and ²³²Th after acute soil ingestion. The blood ²³⁸U (0.750%) and ²³²Th (0.028%) reach their maximum f_ab values after 48 h. The ²³⁸U (f_ab: 0.169-0.652%) accumulates mostly in the kidney, whereas the ²³²Th (f_ab: 0.004-0.021%) accumulates primarily in the bone. Additionally, ²³⁸U is more bioavailable than ²³²Th. Post 48 h acute ingestion demonstrates noticeable histopathological and hematological alterations, implying that intake of ²³⁸U in co-contaminated soil can lead to erythrocytes and proximal tubules damage, whereas, ²³²Th intake can harm erythrocytes. Our study provides new directions for future research into the health implications of acute oral exposures to ²³⁸U and ²³²Th in co-contaminated soils. The findings offer significant insight into the utilization of in vivo SD rat testing to estimate ²³⁸U and ²³²Th bioavailability and toxicity in exposure assessment.

• The Journal of Korean Medicine
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• v.44 no.2
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• pp.119-131
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• 2023

Objectives: Betula Platyphylla(BP) has been used as a analgesic, anti-microbial, anti-oxidant drug in Eastern Asia. However, it is still unknown whether BP ethanol extract could exhibit the inhibitory activities against ultraviolet B(UVB)-induced skin injury on human keratinocytes, HaCaT cells. This study was aimed to investigate the protective activity of BP ethanol extract on UVB-irradiated skin injury in HaCaT cells. Methods: The skin injury model of HaCaT cells was established under UVB stimulation. HaCaT keratinocyte cells were pre-treated with BP ethanol extract for 1 h, and then stimulated with UVB. Then, the cells were harvested to measure the cell viability, production of reactive oxygen species(ROS), pro-inflammatory cytokines such as interleukin(IL) 1-beta, IL-6, and tumor necrosis factor(TNF)-𝛼, hyaluronidase, type 1 collagen, matrix metalloproteinase(MMP)s. In addition, we examined the mitogen activated protein kinases(MAPKs) and inhibitory kappa B alpha(I𝜅;-B𝛼) as inhibitory mechanisms of BP ethanol extract. Results: The treatment of BP ethanol extract inhibited the UVBinduced cell death and ROS production in HaCaT cells. BP ethanol extract treatment inhibited the UVB-induced increase of IL-1beta, IL-6, and TNF-𝛼. BP ethanol extract treatment inhibited the increase of hyaluronidase, MMP and decrease of collagen. BP ethanol extract treatment inhibited the activation of MAPKs and the degradation of I𝜅-B𝛼. Conclusions: Our result suggest that treatment of BP ethanol extract could inhibit the UVB-induced skin injury via deactivation of MAPKs and nuclear factor kappa B(NF-𝜅B) in HaCaT cells. This study could suggest that BP ethanol extract could be a beneficial agent to prevent skin damage or inflammation.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.05a
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• pp.43-45
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• 2021

The short-term quantitative precipitation prediction (QPF) system is important socially and economically to prevent damage from severe weather. Recently, many studies for short-term QPF model applying the Deep Neural Network (DNN) has been conducted. These studies require the sophisticated pre-processing because the mistreatment of various and vast meteorological data sets leads to lower performance of QPF. Especially, for more accurate prediction of the non-linear trends in precipitation, the dataset needs to be carefully handled based on the physical and dynamical understands the data. Thereby, this paper proposes the following approaches: i) refining and combining major factors (weather radar, terrain, air temperature, and so on) related to precipitation development in order to construct training data for pattern analysis of precipitation; ii) producing predicted precipitation fields based on Convolutional with ConvLSTM. The proposed algorithm was evaluated by rainfall events in 2020. It is outperformed in the magnitude and strength of precipitation, and clearly predicted non-linear pattern of precipitation. The algorithm can be useful as a forecasting tool for preventing severe weather.

• Steel and Composite Structures
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• v.46 no.1
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• pp.53-73
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• 2023

Man-made structure materials like concrete usually contain inclusions. These inclusions affect the mechanical properties of concrete. In this investigation, the influence of inclusion length and inclination angle on three-dimensional failure mechanism of concrete under uniaxial compression were performed using experimental test and numerical simulation. Approach of acoustic emission were jointly used to analyze the damage and fracture process. Besides, by combining the stress-strain behavior, quantitative determination of the thresholds of crack stress were done. concrete specimens with dimensions of 120 mm × 150 mm × 100 mm were provided. One and two holes filled by gypsum are incorporated in concrete samples. To build the inclusion, firstly cylinder steel tube was pre-inserting into the concrete and removing them after the initial hardening of the specimen. Secondly, the gypsum was poured into the holes. Tensile strengths of concrete and gypsum were 2.45 MPa and 1.5 MPa, respectively. The angle bertween inclusions and axial loadind ary from 0 to 90 with increases of 30. The length of inclusion vary from 25 mm to 100 mm with increases of 25 mm. Diameter of the hole was 20 mm. Entirely 20 various models were examined under uniaxial test. Simultaneous with experimental tests, numerical simulation (Particle flow code in two dimension) were carried out on the numerical models containing the inclusions. The numerical model were calibrated firstly by experimental outputs and then failure behavior of models containing inclusions have been investigated. The angle bertween inclusions and axial loadind vary from 0 to 90 with increases of 15. The length of inclusion vary from 25 mm to 100 mm with increases of 25 mm. Entirely 32 various models were examined under uniaxial test. Loading rate was 0.05 mm/sec. The results indicated that when inclusion has occupied 100% of sample thickness, two tensile cracks originated from boundaries of sample and spread parallel to the loading direction until being integrated together. When inclusion has occupied 75% of sample thickness, four tensile cracks originated from boundaries of sample and spread parallel to the loading direction until being integrated together. When inclusions have occupied 50% and 25% of sample thickness, four tensile cracks originated from boundaries of sample and spread parallel to the loading direction until being integrated together. Also the inclusion was failed by one tensile crack. The compressive strength of samples decease with the decreases of the inclusions length, and inclusion angle had some effects on that. Failure of concrete is mostly due to the tensile crack. The behavior of crack, was affected by the inclusion length and inclusion number.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.2
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• pp.143-155
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• 2023

Percutaneous coronary intervention and acute coronary syndrome are both closely tied to the frequently occurring complication of coronary microembolization (CME). Resveratrol (RES) has been shown to have a substantial cardioprotective influence in a variety of cardiac diseases, though its function and potential mechanistic involvement in CME are still unclear. The forty Sprague-Dawley rats were divided into four groups randomly: CME, CME + RES (25 mg/kg), CME + RES (50 mg/kg), and sham (10 rats per group). The CME model was developed. Echocardiography, levels of myocardial injury markers in the serum, and histopathology of the myocardium were used to assess the function of the cardiac muscle. For the detection of the signaling of TLR4/MyD88/NF-κB along with the expression of pyroptosis-related molecules, ELISA, qRT-PCR, immunofluorescence, and Western blotting were used, among other techniques. The findings revealed that myocardial injury and pyroptosis occurred in the myocardium following CME, with a decreased function of cardiac, increased levels of serum myocardial injury markers, increased area of microinfarct, as well as a rise in the expression levels of pyroptosis-related molecules. In addition to this, pretreatment with resveratrol reduced the severity of myocardial injury after CME by improving cardiac dysfunction, decreasing serum myocardial injury markers, decreasing microinfarct area, and decreasing cardiomyocyte pyroptosis, primarily by blocking the signaling of TLR4/MyD88/NF-κB and also reducing the NLRP3 inflammasome activation. Resveratrol may be able to alleviate CME-induced myocardial pyroptosis and cardiac dysfunction by impeding the activation of NLRP3 inflammasome and the signaling pathway of TLR4/MyD88/NF-κB.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.30 no.4A
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• pp.337-342
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• 2010

Generally most sluice gates are closed and opened by a mechanical winch, a winch using an oil-pressure, or a winch mixing both. Because of their size and structure, they should be safely operated with more than two pulling devices helping each other. At the moment of their opening and closing, there usually occur some additional loads to the structure which cannot be exactly measurable at the stage of designing. Such additional loads can cause the sluice gate to be unbalanced and make it hard to open and close the gate, and by also overloading a winch, they can inflict a significant damage to the safety of the sluice gate. This paper explains a FDC(Force-Displacement Control) system which simultaneously considered the oil-pressure and displacement in order to evenly distribute the force and make a winch balanced at the opening and closing motion. This FDC system was implemented by means of the PID(Proportional Integral Derivative) function of XG 5000 program. It was experimented on a model of the sluice gate winch with the hydraulic oil pressure cylinder. The experiments showed that the developed FDC system made the winch of hydraulic oil pressure cylinder open and close cooperatively in spite of various external loads. Therefore the FDC system is proven effective when it is applied to a winch of sluice gate.