• Journal of Digital Convergence
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• v.11 no.8
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• pp.359-365
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• 2013

Companies recently tend to move their business sites to a customer-centered location and the work place is changed from specific time and place to a working environment of anytime and anywhere the job can be done. Therefore, the design and implementation of business-work management system using mobile applications has been actively researched. In this study, the business-work management system, a mobile application using GPS, is immediately transmitted to ERP system and is stored into a company's formula DB, at such sites outside the company as business trip destinations, training institutions, and outside meetings, through smartphone-based GPS location information using WiFi, 3G, LTE, or 4G. In this way, it is aimed to design and develop the mobile application system to obtain rapid authorization in connection with electro nic document approval system. Also, this study is to measure the system's productivity and expected effects through the users' survey results by actual application of the designed and developed system to companies.

• Journal of the Korea Convergence Society
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• v.11 no.1
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• pp.17-23
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• 2020

Recently, due to increases in the numbers of nursing students, there are many cases of clinical practice in remote areas other than in hospitals near a school. In this regard, the Korea Institute of Nursing Evaluation emphasizes the securing of safety, the provision of regulations, and countermeasures related to long-term practices of nursing students. The purpose of this study is to develop a safety management application for nursing students who are practicing at a distance. This application configuration consists of accommodation location information, nursing student location information check, and notification of the professor in charge. The location information of nursing students was based on their location on weekdays from 10 pm to 11 pm, due to the work schedule of the nursing students. For this reason, nursing students can use this app after their clinical practice; if the student is out of the safety radius or there is a problem, a risk notification can be provided through a service and a rescue request can be made.

• Archives of Pharmacal Research
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• v.24 no.1
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• pp.55-63
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• 2001

Aucubin, an irdoid g1ucoside, was investigated to determine whether it has a stimulating effect on $\alpha$-amanitin excretion in $\alpha$-amanitin intoxicated rats, and whether there is binding activity to calf thymus DNA. High-performance liquid chromatography (HPLC) analysis of $\alpha$-amanitin in rat urine allowed quantitative measurement of the $\alpha$-amanitin concentration with a detection limit of 50${mu}g/ml$. In this system, a group treated with both $\alpha$-amanitin and aucubin showed that o(-amanitin was excreted about 1.4 times faster than in the $\alpha$-amanitin only treated group. Our previous results showed that the toxicity of $\alpha$-amanitin is due to specific inhibition of RNA polymerase activity and the resultant blockage of the synthesis of certain RNA species in the nucleus. However, no significant activity change on RNA polymerase from Hep G2 cells was observed when aucubin was treated with $\alpha$-amanitin at any concentration tested. Nevertheless, aucubigenin inhibited both DNA polymerase (IC50, 80.5${mu}g/ml$) and RNA polymerase (IC50, 135.0${mu}g/ml$) from the Hep G2 cells. The potential of both $\alpha$-amanitin and aucubin to interact with DNA were examined by spectrophotometric analysis. $\alpha$-Amanitin showed no significant binding capacity to calf thymus DNA, but aucubin was found to interact with DNA, and the apparent binding constant ($K_{app}$) and apparent number of binding sites per D7A phosphate ($B_{app}$) were 0.45$0.45{\times}$$10^4$ $M^{-1}$ and 1.25, respectively.

• Journal of Pharmaceutical Investigation
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• v.25 no.4
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• pp.353-363
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• 1995

The purpose of this study was to investigate the intestinal and nasal absorption enhancement of cefotaxime (CTX) by ion-pairing with counterions and to design an effective oral and intranasal drug delivery system for antibiotics. Counterions for absorption promotion were cationic surfactants [cetylpyridinium chloride (CP), cetrimide (CT) and benzalkonium chloride (BA)]. In the presence of counterions, the apparent partition coefficient of cefotaxime was increased depending on the molar concentration of the counterions. Anion interference was observed for ion-pairing of cefotaxime with counterions because of the counterbalance between an anion and counterions. The present study employed the in situ simultaneous nasal and intestinal perfusion technique in rats. The apparent permeabilities $(P_{app})$ of cefotaxime were $1.43{\pm}0.04{\times}10^{-5}\;cm/sec(mean{\pm}S.E)$ in the nasal cavity and 0 in the jejunum, respectively, which indicated that the intrinsic absorptivity of cefotaxime was greater in the nasal cavity than in the jejunum. When ionupairing formers were used, the decreasing order of apparent cefotaxime permeability $(P_{app},\;10^{-5}\;cm/sec)$, corrected for surface area of absorption, was as followings: $BA\;(7.50{\pm}0.36)\;>\;CT\;(4.92{\pm}0.24)\;>\;CP\;(3.01{\pm}0.17)$ in the jejunum and $BA\;(22.31{\pm}1.36)\;>\;CP\;(18.24{\pm}0.81)\;>\;CT \;(16.22{\pm}1.87)$ in the nasal cavity. The increase in permeability of cefotaxime was about 13-fold in the rat nasal cavity and was marked in the rat jejunum for ion-pairing with counterions as compared to those without ion-pairing. The damages of jejunal and nasal mucosal membrane by counterions were observed within approximately 2hrs after removal of ion-pair of cefotaxime with counterions from the nasal cavity and jejunum. These results suggest that CP can be used as an ion-pairing former in the jejunum and CP and CT can be used as ion-pairing formers in the nasal cavity for cefotaxime, as well as for poorly absorbed drugs with a negative charge due to ionization.

• Journal of Korea Society of Industrial Information Systems
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• v.19 no.5
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• pp.103-115
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• 2014

Mobile-Office is the IT office that enables people handle their business anywhere and anytime without going to head office. It has propagated rapidly in domestic and foreign companies as the users who use mobile terminal such as smartphone have increased sharply. Mobile-Office is emerging as a new way of conducting business. It requires business environment to be changed to improve business efficiency, as fast-growing mobile-based economies emerges. Small and medium-sized companies's utilization ability for advanced IT technology is insufficient, and limitations exist on capacity of building and investment. They need different development methodologies and utilization methods. The purpose of this study is not only to consider the previous business environment problem on accessibility, mobility, effectiveness, complexity and consolidation, but to search more efficient methods for introducing applications to utilize various smart devices and websites with minimum investment in R&D.

• Journal of Korean Biological Nursing Science
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• v.25 no.3
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• pp.215-227
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• 2023

Purpose: The aim of this study was to develop a mobile app-based musculoskeletal exercise program (AMSEP) for operating room (OR) nurses and evaluate its effects on self-efficacy, the flexibility of the shoulders, lower back, and legs, and musculoskeletal symptoms and fatigue. Methods: The AMSEP was developed based on the information-motivation-behavioral skill model. In total, 48 OR nurses were recruited at a university hospital in Korea and divided into an experimental group (n=24) and a control group (n=24), matched for career experience in the OR. The experimental group participated in the AMSEP, while the control group received a booklet regarding musculoskeletal exercise. Results: The experimental group showed significant increases in self-efficacy (t = -2.77, p = .008) and flexibility of the right shoulder (t = -4.08, p < .001), left shoulder (t = -3.28, p = .002), lower back (t = -3.75, p < .001), and legs (t = -3.96, p < .001) compared to the control group. Musculoskeletal symptoms (t = 2.75, p = .008), and fatigue (Z = -1.98, p = .048) significantly decreased in the experimental group compared to the control group. Conclusion: Our findings indicate that the AMSEP for OR nurses provided information on the prevention of musculoskeletal disorders and methods of exercise, as well as an opportunity for continued exercise performance through self-management. The AMSEP was easily accessible and effective in increasing self-efficacy and flexibility and reducing musculoskeletal symptoms and fatigue.

• Journal of Service Research and Studies
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• v.5 no.2
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• pp.111-118
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• 2015

Although the development of mobile devices are made us a free life, they were displayed the subject of this financial crime and attacking forces in the other side. Among finance-related crime is become a serious crime that are targeting smartphones by SMS phishing, phishing, pharming, voice phishing etc. In particular, SMS phishing is increased according to phenomenon using the nature of a text message in the mobile. SMS phishing is become new crime due to the burden to the smartphone user. Their crime is also the advanced way from the existing fraud, such as making the malicious apps. Especially it generates loopholes in the law by a method such as using a foreign server. For safe from SMS phishing attacks, proactive pre-diagnosis is even more important rather than post responses. It is necessary to deploy blocking programs for detecting SMS phishing attacks in advance to do this. In this paper we are investigating the process of block types and block apps that are currently deployed and presenting the evaluation of the application of the detection block setting app.

• Journal of Korean Society of Water and Wastewater
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• v.10 no.3
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• pp.64-72
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• 1996

The one of the most important factors we shoud consider in designing the processes using porous media such as activated carbon adsorber is the prediction of the breakthrough curve. In this study, the breakthrough curve of BAC process for the treatment of refractory pollutants was evaluated by simplified engineering analysis. Through the experiments, the slope of the breakthrough curve can be determined by retardation factor, R and apparent dispersion coefficient, $D_{app}$ which is determined by hydrodynamic dispersion, mass transfer effects and isotherm. Estimated concentration of effluent was agreed with the experimental values. Also, it is possible to use this method for predicting the breakthrough curve of the pollutants removal and tranport of pollutants in porous media.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2001.09a
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• pp.131-138
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• 2001

The purpose of this study is to investigate size effect on inelastic behavior of reinf bridge piers subjected to cyclic load. A computer program, named RCAHEST(Reinforced Co Analysis in Higher Evaluation System Technologr), for the analysis of reinforced concret was used. Material nonlinearity is taken into account by comprising tensile, compressiv models of cracked concrete and a model of reinforcing steel The smeared crack app incorporated. In boundary plane at which each member with different thickness is conne discontinuous deformation due to the abrupt change in their stiffness can be taken into introducing interface element. The effect of number of load reversals with the same d amplitude has been also taken into account to model the reinforcing steel. To determine th on bridge pier inelastic behavior, a 1/4-scale replicate model was also loaded for compar full-scale bridge pier behavior.

• Journal of Conservation Science
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• v.5 no.1 s.5
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• pp.87-93
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• 1996

This study was carried out to Identify wood and charcoal segments, which were excavated in 1994 at the Seohaean highway construction site along the western coast of Korea ; Tuntaeri, Hwasunggun. We identified the objects excavated at the fire places of the Tuntaeri dwelling sites (early Koryo period ; A. D. $11\~12C$) ; charcoal pieces and 1 wood segment, which was used for the handle of a metal hook. Chestnut(Castanea crenata), deciduous oaks(Quercus spp.) and maple(Acer app.) were identified from the charcoals, whereas the wood segment as willow species(Salix spp.). These species seem to represent warm and wet climate in the middlewest Korea during $11\~12C$.