• Title/Summary/Keyword: cycloaddition

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The First Synthesis of Dually Modified Southern-Mimicking Nucleoside: 4'-Methyl Branched and Bicyclo [3.1.0] Hexane Locked Nucleoside

  • Kim, Kwan-Woo;Hong, Joon-Hee
    • Bulletin of the Korean Chemical Society
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    • v.25 no.5
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    • pp.668-672
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    • 2004
  • This paper reports the stereoselective synthesis of a novel nucleoside, 4'-methyl branched and bicyclo [3.1.0] hexane locked-nucleoside 12, using a sequential [3,3]-sigmatropic rearrangement/carbene cycloaddition reaction/Curtius reaction strategy with a high stereoselectivity.

Synthesis of Polymers Including Both Triazole and Tetrazole by Click Reaction

  • Shin, Jung-Ah;Lim, Yeong-Gweon;Lee, Kyung-Hee
    • Bulletin of the Korean Chemical Society
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    • v.32 no.2
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    • pp.547-552
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    • 2011
  • Azido contained polymers were treated with various substituted N-propargyl tetrazoles in $CH_2Cl_2/H_2O$ at room temperature by Cu-catalyzed [2+3] cycloaddition to afford high yields of the corresponding polymers, possessing both triazole and tetrazole moiety.

Rhodium(III)-mediated cycloaddition reactions of alkynes

  • 한원석;이순원
    • Proceedings of the Korea Crystallographic Association Conference
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    • 2002.11a
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    • pp.30-30
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    • 2002
  • Heating [Cp*Rh(η²-NO₃)(OTf) (1) and PhC≡CPh in EtOH for 3 h gave a η⁴-cyclobutadienerhodium complex, [Cp*Rh(η⁴-C₄Ph₄)] (2). Complex 1 reacted with HC=CPh in acetone at room temperature for 3 h to give a (η⁴-cyclobutadiene)-rhodium complex, [Cp*Rh(η⁴-C₄HPhC=CPh)] (3). Whereas, the reactions of 1 with HC=CCH₂Cl in acetone at room temperature for 3 h gave the triply halide-bridged dinuclear rhodium complex, [Cp*Rh(μ₂-Cl)₃RhCp*](OTf) (4). Complexes 2-4 have been structurally characterized by X-ray diffraction.

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Novel Synthesis of the Natural Protoberberine Alkaloids: Oxypalmatine and Oxypseudopalmatine

  • Le, Thanh Nguyen;Cho, Won-Jea
    • Bulletin of the Korean Chemical Society
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    • v.28 no.5
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    • pp.763-766
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    • 2007
  • Oxypalmatine and oxypseudopalmatine were synthesized in three steps from the benzonitrile 11 and toluamides 12a, b. The lithiated cycloaddition reaction yielded 3-arylisoquinolinone intermediates. A subsequent internal SN2 reaction produced the corresponding 8-oxoprotoberberines, oxypalmatine and oxypseudopalmatine.