[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.5012/bkcs.2004.25.5.668

The First Synthesis of Dually Modified Southern-Mimicking Nucleoside: 4'-Methyl Branched and Bicyclo [3.1.0] Hexane Locked Nucleoside

Kim, Kwan-Woo (College of Pharmacy, Chosun University)
Hong, Joon-Hee (College of Pharmacy, Chosun University)

Publication Information

Bulletin of the Korean Chemical Society / v.25, no.5, 2004 , pp. 668-672 More about this Journal

Abstract

This paper reports the stereoselective synthesis of a novel nucleoside, 4'-methyl branched and bicyclo [3.1.0] hexane locked-nucleoside 12, using a sequential [3,3]-sigmatropic rearrangement/carbene cycloaddition reaction/Curtius reaction strategy with a high stereoselectivity.

Keywords

Locked-nucleoside; [3,3]-Sigmatropic rearrangement; Curtius reaction; Antiviral agents;

Citations & Related Records

Times Cited By KSCI : 1 (Citation Analysis)
Times Cited By Web Of Science : 4 (Related Records In Web of Science)
Times Cited By SCOPUS : 4

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1	Aihong Kim. (2005) Nucleosides, Nucleotides and Nucleic Acids Synthesis and Anti-HCMV Activity of Novel 2′,3′,4′-Trimethyl Branched Carbocyclic Nucleosides / 24 (1) , 63
45	Kwan Woo Kim. (2004) ChemInform The First Synthesis of Dually Modified Southern-Mimicking Nucleoside: 4′-Methyl Branched Bicyclo[3.1.0]hexane Locked Nucleoside. / 35 (45)
23	Yoann Aubin. (2007) Tetrahedron Chemoenzymatic synthesis of novel adenosine carbanucleoside analogues containing a locked 3′-methyl-2′,3′-β-oxirane-fused system / 63 (23) , 5050

1	/ Nucleosides, Nucleotides and Nucleic Acids
2	/ Synlett
3	/ Tetrahedron
4	/ Bioorganic and Medicinal Chemistry