• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.753-757
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• 2013

Objective: To evaluate the relationships between lymph node ratio (LNR, the ratio of positive lymph nodes in excised axillary lymph nodes) and disease-free survival (DFS) by comparing with traditional absolute positive lymph node number (pN classification) for prediction of breast cancer (BC) progrnosis. Methods and Patients: We retrospectively reviewed patients who received comprehensive therapy in Department of Breast Surgery, Hubei Cancer Hospital, China from Jan 2002 to Dec 2006 (Group A), and Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, China from Jun 2008 to May 2012 (Group B). Patients were allocated to low-risk (${\leq}0.20$), intermediate-risk (> 0.20 but ${\leq}0.65$), high-risk (>0.65) groups by LNR. The primary endpoint was 5-DFS. Results: A total of 294 patients were included in our study. LNR was verified as a negative prognostic factor for DFS (P=0.002 in Group A, P<0.0001 in Group B). Then we found the effects of pN and LNR delamination on disease-free survival (DFS) had statistical significance (P=0.012 for pN and P=0.031 for LNR stratification in Group A, both of them P<0.001 in Group B). Compared to pN staging, LNR staging displayed superior performance in prognosis, the adjusted hazard ratio of recurrence being 2.07 (95%CI, 1.07 to 4.0) for intermediate risk group (P=0.030) and 2.44 (95%CI, 1.21 to 4.92) for high risk group (P=0.013) in Group A. Conclusions: LNR stratification proved an adverse prognostic factor of DFS in lymph nodes positive invasive BC using cut-off values 0.20 and 0.65, and was more predictive than traditional pN classification for 5-DFS.

• Journal of Nutrition and Health
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• v.40 no.4
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• pp.385-394
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• 2007

The purpose of this study was to determine the zinc status of preschool children in Ulsan. The study was conducted in 95 children aged 3 to 6 years by investigating the anthropometric indices and assessing the biochemical analysis. The blood was analysed to assess serum zinc and alkaline phosphatase. And a questionnaire for dietary intakes using 24-hr recall method were performed by mothers of 95 subjects. The dietary intakes of children were analysed to determine the prevalence of inadequate and excessive intakes of zinc with Dietary Reference Intakes for Koreans (KDRIs). WHL (Weight-Length Index) and Kaup index were used to define obesity. The overall prevalence of overweight and obese subjects were 14.7% and 6.3% by WHL, were 15.8% and 13.7% by Kaup index. The mean intakes of zinc by children aged 3${\sim}$5y and 6y were 5.5 ${\pm}$ 1.4 mg/d (75.7% RDA) and 6.7 ${\pm}$ 2.0 mg/d, respectively, that was the level exceeding the estimated average requirement (EAR) and the recommended intake (RI) of Korean Dietary Reference Intakes. Less than 1.3% and 7.9% of children had usual zinc intakes below EAR and RI of KDRIs, respectively. The percentages of children with intakes exceeding the tolerable upper intake level (UL) were 2.6%. The zinc nutritional status by biological assay was found that mean serum zinc and alkaline phosphatase (ALP) of total subjects were 64.0 ${\pm}$ 8.4 ${\mu}$g/dl and 72.8 ${\pm}$ 14.9 U/L, there was not a significant difference between boys and girls. The range of serum zinc level was 45${\sim}$89 ${\mu}$g/dl and children with a low serum zinc concentration by several cut-off points were 18.9${\sim}$55.8%, especially. Serum zinc level was positively correlated to the intakes of calorie, calcium, fiber, iron, zinc, zinc/kg and height (p<0.001). Serum ALP was positively correlated height, weight and WLI. The zinc intake of children aiso showed a positive correlation with height and weight. These results indicate that there were significant correlations between the zinc status and growth of preschool children. Preschool children in Ulsan have dietary zinc intakes that exceed the new DRIs. The present level of intake does not seem to pose a health problem, but if zinc intakes with fortified foods and supplements were considered, the amount of zinc consumed by children may become excessive.

• Korean Journal of Medicinal Crop Science
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• v.7 no.4
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• pp.308-313
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• 1999

Direct seeding is a cultivation method of Korean ginseng which can cut down production cost and increase productivity. This study was conducted to obtain detailed information about this method and to aid the development of it in Korea. Major pre-crops before ginseng cultivation were rice, corn and rye, and organic matters, such as rice straw, rye straw and poultry feces were used for basal fertilization. In direct seeding of the ginseng field, seeding density was 196 to 210 seeds per $3.3m^2$ and germination ratio was 67%. Survival ratio of 4-year-old ginsengs which were products of direct seeding was 51%, and more than 100 plants per $3.3m^2$ survived. The most critical diseases in the directly seeded ginseng field were grey mold, damping off, and stem diseases including stem spot disease. Plant growth of the ginseng cultivated by the direct seeding method was not different from the ginseng cultivated by transplanting method. But the root of the ginseng cultivated by the direct seeding method took the shape of a shorter main root compared to the ginseng cultivated by the transplanting method. Root yield per $3.3m^2$ of the direct seeding ginseng field was larger compared to the field of the transplanting cultivation.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.3
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• pp.685-690
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• 2013

This paper has proposed a multi-channel and wide gain-range baseband circuit blocks for the IEEE 802.15.4g MR-OFDM SUN systems. The proposed baseband circuit blocks consist of two negative-feedback VGAs, an active-RC 5th-order chebyshev low-pass-filter, and a DC-offset cancellation circuit. The proposed baseband circuit blocks provide 1 dB cut-off frequencies of 100 kHz, 200 kHz, 400 kHz, and 600 kHz respectively, and achieve a wide gain-range of +7 dB~+84 dB with 1 dB step. In addition, a DC-offset cancellation circuit has been adopted to mitigate DC-offset problems in direct-conversion receiver. Simulation results show a maximum input differential voltage of $1.5V_{pp}$ and noise figure of 42 dB and 37.6 dB at 5 kHz and 500 kHz, respectively. The proposed I-and Q-path baseband circuits have been implemented in $0.18-{\mu}m$ CMOS technology and consume 17 mW from a 1.8 V supply voltage.

• Journal of Korean Ophthalmic Optics Society
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• v.10 no.1
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• pp.27-34
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• 2005

Photochromic lens is the color changing lens from colorlessness to colorness when exposed to UV light. It can protect eyes from UV-B light which cause the cataract and can be used as sunglass in the summer since it can cut off 70~80% of sun light. Surface coating technique was used to develop lens which has 70% light transmittance and of which fading time of color change is within 5 min. Various color lenses were developed so that these had various color such as blue, green, brown, violet, yellow and red etc. Lens has an excellent physical properties, 100% adhesion and 4~5H hardness. The chemical and the scratch resistance of this lens were the greatest and the thermal stability was also higher. The clinical trial of developed lens were applied to 65 patients who had photophobia by various reasons at ophthalmology of Soonchunhyang University Hospital. Results showed that glaring was significantly reduced and the visual health were remarkably improved. Especially, anti-glaring effect in the night was great for the patient who had the LASIK operation. Protection of UV-B and blue light also can prevent the patient from cataract and the yellowish crystalline lens at old ages. Through the result of clinical. trial, we know that photochromic lens could be a new technique for both cure and precaution of photophobia.

• Journal of the Korean Society of Food Science and Nutrition
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• v.29 no.4
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• pp.635-641
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• 2000

In order to utilize the protein source from a fish proessing by-product, cod was hydrolyzed with various enzymes such as tuna pyloric caeca crude enzyme (TPCCE), a-chymotrypsin, trypsin, papain and pronase E. The TPCCE hydrolysate acquired the highest sensory properties on taste, odor and color. The resultant cod rfame protein hydrolysate (CFPH) which was hydrolyzed with TPCCE, was separated through a series of ultrafiltration membranes with molecular weight cut-off (MWCO) of 30, 10, 5 and 1 kDa, and four types of permeates in cluding 30 K (permeate from 30 kDa membrane), 10 K (permeate from 10 kDa membrane), 5 K (permeate from 5 kDa membrane) and 1 K (permeate from 1 kDa membrane) were obtained. The natural sauces were prepared with 30 K, 10 K, 5 K and 1 K hydrolysate, and the sauce prepared with 1 K hydrolysate was the best score in sensory evaluations. In addition the mixed sauce prepared with 1 K hydrolysate and commercial soy sauce was similar to commercial sauce in sensory properties. These results suggest that the mixed sauce would be utilized as the substitute of acid-hydrolysis sauce.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.6C
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• pp.251-258
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• 2011

Steel pipe piles have been used as various deep foundation materials for a long time. Recent increase in steel material cost has made engineers reluctant in using it even with its good quality and ease of construction. Therefore when constructing with steel pipe pile, the decision to reuse the excessive pile length that is cut off from the designed pile head elevation after pile driving can be cost saving. This has caused many constructors to reuse the pile leftovers with new piles, but the absence of quantitative structural capacity behaviors of steel pipe pile after pile driving or appropriate countermeasures and standards in reusing steel pipe pile has resulted in wrong applications, pile structural integrity problems, inappropriate limitation of reusable pile length, etc. The structural performance analysis between a new pile and a pile that has undergone working state and ultimate state stress level during pile driving was performed in this research by means of comparing the results between the dynamic pile load test, tensile load test, charpy energy test and fatigue test for high strength steel of $440N/mm^2$ yield strength. Test results show that under working load conditions the yield strength variation is less than 2% and for ultimate load conditions the variation is less than 5% for maximum total blow count of 3000. The results have been statistically analyzed to check the sensitivity of each factors involved. From the test results, reusability of steel pipe pile lies not in the main pipe yield strength deviation but in the reduction of absorb energy, strength changes and quality control at the welded section, shape deformation and local buckling during pile driving.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.32 no.1
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• pp.68-74
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• 1999

The optimum conditions for selective .elimination of salt from tuna boiled extract (TBE) by electrodialysis were determined. The desalination conditions of TBE were determined at various pH's, concentrations and volumes of TBE. The ion-exchange membrane with a molecular weight cut off 100Da was used for desalting of TBE. The desalination times on $1\%$ and $10\%$ of TBE concentrations were 40 min and 240 min, respectively. The electrodialysis process could removed above $95\%$ of the initial salt content in $1\%$ and $10\%$ of TBE concentrations. The desalination of TBE at pH 4.0 was $14\%$ higher than that at pH 9.0 The amount of water transferred by the electrodialysis was determined. The electrodialysis process could remove above $90\%$ of the initial salt content in $5\%$ TBE for 80 min. The initial volume and the permeate did not have significant effects on desalination time and ratio. The key parameters for the desalination of TBE were pH and concentration of TBA.

• Journal of Korean Society of Environmental Engineers
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• v.30 no.10
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• pp.1047-1053
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• 2008

This study was to evaluate the optimum conditions for chemical coagulation to remove color from the effluent of a piggery wastewater treatment process. The DOC concentration in the effluent was about 227.3 mg/L, color was 2,430 CU, turbidity was 22.1 NTU, and UV$_{254}$-absorbance was 3.7 cm$^{-1}$. The fractions of hydrophobic, transphilic, and hydrophilic substance of the effluent was about 55.3%, 17.4%, 27.3% respectively. Also, molecular weight cut-off(MWCO) of below 0.5 K, 0.5 K to 1 K, 1 K to 10 K, 10 K to 30 K, and over 30 K were 74.2%, 7.3%, 5.5%, 7.1%, and 5.9% respectively. SCD(streaming current Detector) was used to find out the optimum pH values and coagulant dosages. The optimum dosages and pH of Al$^{3+}$ were 5.84 mM and 5.3, while those of Fe$^{3+}$ were 9.25 mM and 5.0, respectively. At optimum conditions of coagulation, color removal efficiencies for aluminium sulfate and ferric chloride were as high as 91.9 and 98.7%, respectively. Chemical coagulation showed good performance to remove color from on biologically treated piggery wastewater.

• Clinical and Experimental Pediatrics
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• v.50 no.4
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• pp.348-354
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• 2007

Purpose : Perinatal hepatitis B viral infection is decreasing; however, 10% of babies to HBeAg positive mothers still become chronic carriers despite perinatal prophylaxis. Although, the cause of prophylaxis failure is still unclear, an importance of maternal HBV-DNA level at the delivery time has been suggested. This study was established to certify if it would be a useful predictable factor for the outcome of perinatal prophylaxis. Methods : Twenty-nine HBeAg positive mothers whose babies had known outcomes of prophylaxis were selected. To determine the amount of maternal HBV-DNA, a quantitative PCR was performed with the WHO International Standard for HBV DNA NAT assays. Results : The mean logarithm HBV-DNA level of mothers with failed outcomes was significantly higher than that of mothers with succeessful outcomes (7.99 vs. 6.72, P=0.015). The predictable maternal HBV-DNA cut-off level to prophylaxis outcome was $2.83{\times}10^7copies/mL$ (100 pg/mL). None out of the case 16 (0%) who had below this level, and 5 out of 13 (38.5%) who had above this level of maternal HBV-DNA failed in perinatal prophylaxis. Conclusion : Mothers with higher levels of HBV-DNA at delivery time would be prone to a worse outcome of prophylaxis using the conventional approach. Perinatal prophylaxis failure rate can be reduced, if we try to introduce more potent prophylactic treatment into the cases with this risk factor.