• 산업융합연구
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• 제18권4호
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• pp.51-59
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• 2020

본 연구는 만성 뇌졸중 환자를 대상으로 저항운동이 포함된 거울치료 시 tDCS(transcranial direct current stimulation)의 융합 자극을 통해 마비측 다리의 근력과 보행 능력의 개선을 알아보고자 하였다. 12명의 뇌졸중 환자는 실험군 당 6명씩 무작위로 할당하였다. 실험군I(n=6)은 NDT(neurodevelopmental treatment)와 거울치료 시 sham tDCS의 융합자극군, 실험군II는 NDT와 거울치료 시 tDCS의 융합자극군으로 나누어 각각 30분씩, 주5회, 총4주 동안 실험을 실시하였다. 모든 평가는 중재 전과 중재 4주 후에 실시하였다. 다리근력은 측정한 모든 근육에서 실험군I에 비해 실험군II에서 유의한 차이를 나타냈고(p<.05), 변화량을 통한 군 간 비교에서는 quadriceps(p<.01)와 tibialis anterior(p<.01)에서 유의한 차이를 나타냈다. 보행능력은 실험군I과 실험군II 모두에서 유의한 차이를 나타냈고(p<.05), 변화량을 통한 군 간 비교에서 유의한 차이를 나타냈다(p<.01). 거울치료와 tDCS의 융합자극은 마비측 다리 근력 및 보행능력 향상에 중첩효과를 통한 긍정적인 개선 효과를 주는 것을 알 수 있었다.

• 대한통합의학회지
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• 제9권4호
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• pp.283-289
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• 2021

Purpose : The purpose of this study is to investigate the effect of mid frequency electrical stimulation during squat exercise on the muscle activity and muscle activity ratio of vastus medialis oblique and vastus lateralis, and to prepare scientific basic data for exercise intervention using mid frequency electrical stimulation. Methods : This study was conducted with students from University C located in Busan, and among a total of 123 subjects, 12 subjects who complained of knee joint dysfunction between 80 and 90 points using the Kujala patellofemoral score (KPS) were used. All subjects participated in the experiment for 3 days, and MVIC values were measured for normalization of muscle activity values on the first day. For the two days, participants participated in the experiment and performed squat exercise or squat exercise receiving mid-frequency electrical stimulation in random order. Measurements were taken in the squat position immediately after the squat exercise, and muscle activities of vastus medialis oblique and vastus lateralis were measured. The measured data were compared through the dependent t test, and the statistical significance level was set to .05. Results : According to the results of this study, in the case of applying mid-frequency electrical stimulation together in the ratio of vastus medialis oblique and vastus lateralis muscle activity during squat exercise, higher values were observed compared to the case of not applying mid-frequency electrical stimulation together, and statistically significant. Also, when mid-frequency electrical stimulation was applied to both vastus medialis oblique and vastus lateralis activities during the squat exercise, higher values were shown compared to the case where the mid-frequency electrical stimulation was not applied together, but there was no statistically significant difference. Conclusion : The results of this study reported that mid-frequency electrical stimulation provided to vastus medialis oblique increased the muscle activity ratio of vastus medialis oblique and vastus lateralis. Therefore, the improvement of coordination due to the enhancement of the activity of vastus medialis oblique through mid-frequency electrical stimulation will be more helpful in the treatment of patellofemoral pain syndrome patient. In addition, it is hoped that the electrical stimulation method applied to exercise will be widely used.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 하계종합학술대회 논문집(5)
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• pp.99-102
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• 2000

This study analyze of reflection wave to Acoustic stimulation on acupoints and contrast parts for objectification of the meridian substance. In order to verify meridian pathway and channel theory of bio-energy in body. It was analyzed response characteristic of reflection waves after acoustic stimulation by sound wave of 5 specific tones. The response characteristics of reflection are measured by the average current magnitude of meridian. The current variation ratio are Live Meridian(gung) 33.2%, Heart Meridian(sang) 30.7%, Kidney Meridian (gak) 33.1%, Spleen Meridian(chi) 33.9%, Lung Meridian (wo) 30.7% compare with contrast parts (non-acupoint and meridian). Therefore meridian is distinguished to non-meridian and 5 vital meridians have relationship with sound wave of 5 specific tones.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.139-140
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• 1998

Urinary incontinence therapy system has been developed using electric stimulation and biofeedback techniques. In the electric stimulation, bipolar current pulses with the frequency of 10-50Hz were applied to vagina muscle. To alleviate possible skin burning caused by locally focussed current silicone electrodes rather than conventional steel electrodes have been developed.

• The Journal of Korean Physical Therapy
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• 제7권1호
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• pp.1-8
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• 1995

The purpose of this study was to determine the effects of high voltage pulsed current(HVPC) and low voltage pulsed current(LVPC) on posttraumatic edema formation in frog hind limbs In this study, 16 bullfrogs(Rana Catesbeiana), weighting 189g to 340g were used. Limb 16 anesthetized bullfrogs were systemically injuried by weight drop. One hind limb of each frogs was randomly selected to receive continuous 120 pps HVPC and 100 pps LVPC at $90\%$ of motor threshold(HVPC : 33.3v, LVPC : 0.2-1mA). The opposite hind was remained as a control. A series of six 30-minute treatment(interrupted by 30-minute rest) was begun minutes after injury. The results were as follows. 1. Cathodal HVPC has heed shown to be effective in curbing posttraumatic edema formation in frogs, but anodal HVPC did not effect. 2. Volumes of hind limbs treated with LVPC were not significantly different over time from those of untreated hind limbs. 3. Therefore, waveform(HVPC versus LVPC) seems to influence the efficacy of electrotherapy for edema control. 4. Electrical stimulation were not increased edema formation on frog hind limbs.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 1999년도 추계학술대회 논문집
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• pp.491-494
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• 1999

We have examined the electrical properties of arachidic acid Langmuir (L) films by using a displacement current measuring technique with pressure stimulation. We give pressure stimulation into organic thin films and detect the Induced displacement current. The structure of manufactured device is Au/arachidic acid/Al, the number of accumulated layers are 17, 19 and 21. Also, we then examined of the MIM device by means of I-V The I-V characteristic of the device is measured from 0 to +1[V]. The insulation property of a thin film is better as the distance between electrodes is larger.

• Journal of Chest Surgery
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• 제22권4호
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• pp.548-561
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• 1989

In single atrial cells isolated from the rabbit the properties of inward current of Na-Ca exchange were investigated using the whole cell voltage clamp technique. The current was recorded during repolarization following brief 2 ms depolarizing pulse to +40 mV from a holding potential of * 70 mV. Followings are the results obtained: 1. When stimulated every 30 seconds, the inward currents were activated and reached peak values 6-12 ms after the beginning of depolarizing pulse. The mean current amplitude was 342 pA/cell. 2. The current decayed spontaneously from the peak activation and the time course of the relaxation showed two different phases fast and slow phase. The time constants were 10-18 ms and 60-140 ms, respectively. 3. The recovery of inward current was tested by paired pulse of various intervals. The peak current recovered exponentially with time constant of 140 ms and 1 p M isoprenaline accelerated the recovery process. 4. Relaxation time course was also affected by pulse interval and time constant of the fast phase was reduced almost linearly according to the decrease of pulse interval between 30 sec and 1 sec. 5. The peak activation was increased in magnitude by long prepulse stimulation, 5 p M Bay K, 1 p M isoprenaline or internal and external application of c-AMP. 6. The relaxation time constant of the fast phase was prolonged by 5 p M Bay K or c-AMP, and shortened by isoprenaline. However the time course of the slow relaxation phase was not so much changed. From the above results, it could be concluded that increase of the calcium current by Bay K or c-AMP results in the potentiation and prolongation of intracellular calcium transient, and the facilitation of Ca uptake by SR might be a mechanism of shortening the time constant of current relaxation by short interval stimulation or isoprenaline.

• 대한물리치료과학회지
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• 제2권2호
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• pp.495-508
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• 1995

The purpose of this study was to determine the effects of high voltage pulsed current (HVPC) stimulation on wound healing. Thirty-four Sprague-Dawley adult female rats were assigned to experimental and control groups. Each rats were anesthetized with pentotal sodium, and a 10 mm full-thickness incision was made on the back. From 24 hours after surgery, the rats of experimental groups were stimulated with HVPC, $140{\mu}s$, 120 pps, 30-40 V for 30 minutes, daily. The rats were sacrified 2 days, 4 days and 6 days after stimulation, respectively. The skin was removed, and processed for light microscopic examination. The length of incisional wounds were measured by microcaliper, and nucleolar organizer regions were counted under light microscope. For the histological observations the specimens were stained with Hematoxylin and Eosin, Masson Trichrome, Gomori Reticulum and Ag-NOR. There was a significant decrease in the length of incisional wound in experimental group compared with control group at 6 days HVPC stimuation (p<0.05). In experimental group, wound were significant difference (p<0.01) between the duration of post surgery. The mean numbers of nucleolar organizer regions per nucleus were significantly increased in the experimental group at 6 days HVPC stimulation (p<0.05), and were significantly difference (p<0.01) between the duration of post surgery in experimental group. Histological examination of the wound site suggested a more rapid of epithelialization and collagen formation between experimental groups compared with control groups. The result may indicated that the HVPC with $140{\mu}s$, 120 pps, 30-40 V for 30 minutes promoted surgical wound healing in the rat.

• 한국콘텐츠학회논문지
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• 제9권11호
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• pp.289-296
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• 2009

본 논문에서, 생물계로 자기자극장치를 사용할 경우 잠재적인 사용에 대한 전력소자 응용제어 기술에 대해 언급 하고자 한다. 자기자극장치의 효과는 자기 자극코일에 의해 전달된 전류 펄스파형에 유도한 전계와 기하학 구성에 의존한다. TMS는 두뇌에 있는 전계를 유도하는 전자장의 펄스를 머리의 외부에서 자극하게 된다. TMS는 두뇌의 자극을 통해, 진단 및 치료에 있는 수많은 응용이 가능하다. 이러한 요소들은 코일의 구성과 전원 장치와 크기의 등가적 요구와 특성으로 매우 중요한 기능을 가지게 된다. 제안하고자 하는 해결방법은 입력에 대하여 가변크기와 주기를 가지는 전류펄스 발생을 가진다. 또한, 해결방법은 전원에서 부하로 에너지 전송과 축적의 요소를 기본으로 할 수가 있다. 제안한 방식으로, 전력 회로 매개 변수의 충분한 통제를 통한 기획과 전략으로 단극파형 또는 양극 파형을 얻을 수가 있었다.

• 대한의생명과학회지
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• 제27권2호
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• pp.99-104
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• 2021

Treatment techniques that affect homeostasis by non-invasive regulation in peripheral organs will advance disease research. Here, we demonstrate a non-invasive method of conditioning within an organ using a low-frequency stimulator superposition of alternating microcurrent wave in stages. It is first applied to the inflammatory response in H3N2-infected sinusitis mice. To check the progress of the treatment, mice were sacrificed every week for 3 weeks, nasal tissue was removed, and the inflammatory response was investigated through H & E staining. The low-frequency stimulation treatment group was found to alleviate the proliferation of epithelial cells and invasion of inflammatory cells compared to the control group as the passage of treatment time. The reduction of inflammatory cytokines in the nasal lavage fluid was observed in H3N2-infected sinusitis mice treated with of low-frequency stimulation using superposition of alternating microcurrent wave compared to H3N2-infected sinusitis mice after 3 weeks. These data demonstrate that low-frequency stimulation device in the form of using alternating current wave superposition on within organs provides a new method to regulate specific physiological functions. Therefore, it is necessary to prove the inhibitory effect of low-frequency stimulation using alternating current wave superposition on inflammatory diseases by various methods through further studies and clinical studies.