• Title/Summary/Keyword: current stimulation

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A Study on Neuroactive Response Measurement Platform using Mechano Sensor (Mechano sensor를 이용한 신경자극반응 측정 플랫폼에 관한 연구)

  • Kim, Woo-Ram;Kim, Young-Kil
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2012.05a
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    • pp.198-201
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    • 2012
  • This is a study about a platform realization measuring the extent of reaction in nerve, as giving a electrical impulse on a nerve pulp regulating a function of muscle, about a measurement of nerve reaction in the amount of current, the lasting time of current, and the position of electrode from a electrical impuls. The position of an electrode in a electrical nerve impuls have nothing to do with all nerves from exercise to all things. There is the Single Twitch Stimulation, Train-of-four, and Double Burst Stimulation in the form of nerve stimulation. This report is needed for selecting MCU of low electric power for a base in embedded system and measuring the extent of reaction after making a sensor interface to know sensitivity of measuring sensor in basic reaction of nerve impuls. The platform is realized to select a high efficiency AD Convertor for raising accuracy in measured data. As the platform in this report was developed for a medical appliances, it was designed to consider user safety in electric power Isolation when making electric power circuit.

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Experiment of Response with Voltage for Stem Cell Regeneration Treatment (줄기세포재생 치료를 위한 배지의 전압 반응 실험)

  • Yoon, Ki-Cheol;Kim, Jung-Tae;Kim, Beom-Su;Lee, Jun;Lee, Jong-Chul
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.41 no.7
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    • pp.809-815
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    • 2016
  • In this paper, the electrical values of resistance, current, and voltage condition of reactivity is analyzed by applying the direct current (DC) voltage in medium for stem cell regeneration treatment. The voltage response by medium is related to electrical stimulation in the process of induction of differentiation for stem cell and the differentiation condition can be checked depending on the response of voltage condition. If the voltage level is lower in reacting response of a medium, the stem cell stimulation condition is stable, and if the voltage changing level is higher, the stem cell stimulation condition is unstable and a considerable loss will be resulted in the differentiation process. In this research, the optimization of electrical stimulation condition is expected for possible stem cell regeneration treatment.

Residual Neuromuscular Sensing Platform Development using Sensor of Nerve Stimulation Response Measurement during Anesthesia (신경자극반응 측정 센서를 이용한 마취 시 잔여근이완 감지 플랫폼 구현)

  • Shin, Hyo-Seob;Kim, Young-Kil
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2010.05a
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    • pp.459-462
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    • 2010
  • Response to nerve stimulation platform for implementing measures to detect finger movement has been functioning as an important factor. This stimulated finger on the nerve and muscle responses would vary. In other words, the finger movement of the muscle response to nerve stimulation and sensing Actuator for the H/W development is needed. In addition, a low power embedded CPU based on the top was used. H/W configuration portion of the isolation power, constant current control, High impedance INA, amplifier parts, and the stimulus mode and the Micro-control the status of current, AD converter Low Data obtained through the processing system is implemented.

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Changes of membrane resistance and membrane potentials by hyperpolarizing current stimulation in mouse unfertilized eggs (과분극 자극에 대한 mouse 미수정란의 세포막저항과 세포막전압의 변화)

  • Hong, Seong-geun;Kim, Ik-hyen;Cho, Young-deok
    • Korean Journal of Veterinary Research
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    • v.31 no.1
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    • pp.33-40
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    • 1991
  • For the observations of both the membrane properties and the excitability on the unfertilized eggs of female mice, changes of the membrane resistance and the membrane potential by hyerpolarizing current stimulation were recorded. As current-voltage relation was linear over the entire range (-180mV~+60mV), membrane resistance($R_m$) was calculated from the amplitude of electrotonic potential to a given stimulus current. Also the presence of anode-break excitation was confirmed. The results were as follows; 1. There was a linear relation between the membrane resistance and resting membrane potential, the expected input resistance was 61. 4M$\Omega$(resting membrane potential was $-18.9{\pm}8.7mV$, mean${\pm}$SD, n=30). 2. Transient depolarization with overshoot was generated just after hyperpolarizing current stimulus and showed the dependency of stimulus duration. 3. Transient depolarization lasted over 30ms, amplitude of these depolarization was increased by high $Ca^{{+}{+}}$(20mM) and inhibited by $Ca^{{+}{+}}$-antagonist, $Mn^{{+}{+}}$. 4. From the above results, it was suggested that the unfertilized mouse egg showed the characteristics of the excitable cell.

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The Effect of SSP Electrical Stimulation Applied to Acupoints Impact on the Swallowing Function of Stroke Patients (경혈점에 적용한 은침전기자극이 뇌졸중 환자의 삼킴기능에 미치는 영향)

  • Gong, Kwang-Sik;Na, Su-Young
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.11 no.1
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    • pp.45-52
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    • 2013
  • Purpose : The goal of this study is to estimate the effect of SSP electrical stimulation applied to acupoints as conducted in oriental medicine on the swallowing function of patients with swallowing difficulties caused by stroke. Methods : Twenty-two hemiplegic stroke patients with swallowing difficulties were divided into an intervention-only group (Group I; n=11) and an intervention-SSP electrical stimulation group (Group II; n=11). Therapeutic intervention was performed on participants in the intervention-only group and the intervention-SSP electrical stimulation group, for 20 minutes per session, three times per week, for four weeks. In this study, SSP electrical stimulation to the acupoints (Cheondol, Yomchon, Budol, Pungji, and Sanyinjian) of stroke patients with swallowing difficulties was applied, and to investigate the effects of SSP electrical stimulation, Clinical dysphagia scale (CDS) and ultrasonography assessment was used to measure pre and post-intervention scores. Results : In the clinical dysphagia scale assessment, the post-intervention score for group II had significant enhancement unlike group I. In the ultrasonography assessment, the hyolaryngeal movement in group II showed significant increase in the swallowing function unlike group I. Conclusion : From the above results, significant effects came from SSP electrical stimulation of 3Hz, biphasic wave, continuous current when applied to the acupoints as conducted in oriental medicine to improve the swallowing function of stroke patients.

Effects of Electrical Stimulation on Patients with Non-Specific Low Back Pain : A Meta-Analysis of Domestic Database (비특이적 만성 허리통증 환자에 대한 전기자극의 효과 : 국내 데이터베이스의 메타분석)

  • Lee, Jeong-Woo;Cho, Sung-Hyoun
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.3
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    • pp.37-52
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    • 2022
  • Purpose : The purpose of this meta-analysis was to evaluate the effects of electrical stimulation on patients with non-specific low back pain. Methods : Domestic databases were gathered from studies that conducted clinical trials associated with electrical stimulation and its impact on pain of non-specific low back patients. A total of 681 studies were identified, with 12 studies satisfying the inclusion data. The studies consisted of patient, intervention, comparison, outcome, and study design (PICO-SD). The search outcomes were items associated with low back pain. Cochrane risk of bias 2 (RoB 2) was used to evaluate the quality of 12 randomized controlled trials. Effect sizes (Hedges's g) in this study were computed as the corrected standard mean difference (SMD). A random-effect model was used to analyze the effect size because of the high heterogeneity among the studies. Egger's regression and 'trim-and-fill' tests were carried out to analyze the publication bias. Cumulative meta-analysis and sensitivity analysis were conducted to analyze the effect according to the sample size and the consistency of the effect size. Results : The following factors had a large overall effect size (Hedges's g=1.28, 95 % CI=.20~2.36) involving electrical stimulation on non-specific low back pain. The subgroup analysis all showed a statistical difference in the types of study design, electrical stimulation, and assessment tool. No statistically significant difference was found in the meta-regression analysis. Publican bias was found in the data. Conclusion : The findings in this study indicate that electrical stimulation interventions have a positive effect on patients with non-specific low back pain. However, due to the low quality of studies and publication bias, the results of our study should be interpreted cautiously.

The Effects of Transcutaneous Electrical Nerve Stimulation and Microampere Electrical Nerve Stimulation on Sympathetic Tone in Healthy Subjects (경피신경전기자극과 미세전류자극이 정상인의 교감신경 긴장도에 미치는 영향)

  • Park Rae-Joon
    • The Journal of Korean Physical Therapy
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    • v.9 no.1
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    • pp.51-57
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    • 1997
  • The purpose of this study was to determine the effect of two different forms of transcutaneous electrical nerve stimulation(TENS) and one of microcurrent high voltage pulsed galvanic current(HVPC) on sympathetic tone in healthy subjects. Fourty subjects received TENS(20) and PVPC(30) during short time(20min). Left finger tip skin temperatures were measured at four interval for each treatment : 1) before treatment, 2) after 10 minutes treatment, 3)after 20 minutes treatment, and 4) after 10 minutes rest. The results were as follows. 1) TENS treatment group increased skin temperature after treatment 20 minutes, but HVPC treatment increased akin temperature after 10 minutes and recovered normal skin temperature after 10 minutes treatment. It means that short time(20min) electrical stimulation decreased sympathetic activities. 2) Sympathetic activities of TENS stimulation were influenced by age, but HVPC were not. 3) During 10 minutes, both treatment increased sympathetic activities, but HVPC treatment reversed sympathetic activity more rapidly than TENS. 4) The changes of skin temperature means by sex, males in TENS treatment group were higher than females, but HVPC were reverted.

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Effects of Electroacupuncture on Motility of the Castro-intestinal Tract of Dogs (전침자극이 개의 위장관운동에 미치는 영향)

  • Sung Jai-Ki;Nam Tchi-Chou
    • Journal of Veterinary Clinics
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    • v.5 no.1
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    • pp.9-21
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    • 1988
  • Gastro-intestinal mortility and transit time of barium sulfate after electroacupuncture were investigated in normal dogs and administration of xylatine in dogs. Electroacupuncture was performed with a current of 1.5 volt and 20 Hz at the acupoints of Tsu San Li(right(+) left(-) in dogs for 30 minutes. The results were as follows: 1. After electroacupuncture stimnlation in normal dogs, rates of stomach contractions was not changed, but amplitudes of stomach motility was markadly increased. The electroacupuncture stimulation tasted about 60 minutes after the end of electroacupuncture. 2. The stomach contractions was markedly increased, while the amplitudes of stomach motility was sligltly decreased by the administration of xylazine in dogs. 3. The rates of stomach contractions and amplitudes of motility were markedly increased after administration of xylazine in the electroacupuncture stimulated dogs. 4. Gastric emptying time o barium sulfate after electroacupuncture stimulation in dogs was highly significantly decreased compared with that of normal dogs(p < 0.01). 5. Small bowel transit time of barium sulfate after electroacupuncture stimulation in dogs was highly significantly decreased compared with that of normal dogs (p < 0.01). 6. Gastroduodenal transit time of barium sulfate after administration of xylazine following electroacupuncture stimulation dogs was blighty significantly decreased compared to that of dogs dosed with xylazine (p< 0.01). 7. Small bowel transit time of barium sulfate after administration of xylazine following electroacupuncture stimulation dogs markedly decreased compared to that of dogs dosed with xylazine (p < 0.05).

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[$Zn^{2+}$ Modulates the Responses of Rat Dorsal Horn Neuron to C-Fiber Stimulation and Excitatory Amino Acids

  • Ahn, Chang-Hoon;Shin, Hong-Kee;Kim, Jin-Hyuk
    • The Korean Journal of Physiology and Pharmacology
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    • v.4 no.6
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    • pp.455-461
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    • 2000
  • Zinc contained in the neurons of central nervous system is activity-dependently released and then attenuates NMDA (N-methyl-D-aspartate)-induced neurotoxicity while augmenting non-NMDA-induced neurodegeneration. Zinc also has been reported to produce antinociceptive action on the inflammation- and nerve injury-induced hyperalgesia in the behavioral test. In this study, we investigated the effects of zinc on the responses of dorsal horn cells to NMDA, kainate and graded electrical stimulation of C-fibers. In the majority of WDR cells (70.6%), zinc current-dependently inhibited WDR cell responses to NMDA and in the remaining cells, produced biphasic responses; excitation followed by inhibition. Zinc augmented the responses of WDR cells to iontophoretical application of kainate. The dominant effect of $Zn^{2+}$ on the responses of WDR cells to C-fiber stimulation was excitatory, but inhibition, excitation-inhibition and no change of the responses to C-fiber stimulation were induced. $Ca^{2+}-EDTA$ antagonized the excitatory or inhibitory effects of $Zn^{2+}$ on the WDR cell responses. These experimental findings suggest that $Zn^{2+}$ modulates the transmission of sensory information in the rat spinal cord.

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Effects of Interferential Current Treatment on Pain, Functional Ability, and Health-Related Quality of Life in Chronic Stroke Patients with Lumbago; A Randomized Controlled Study

  • Jung, Kyoung-Sim;In, Tae-Sung
    • Journal of the Korean Society of Physical Medicine
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    • v.15 no.1
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    • pp.25-32
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    • 2020
  • PURPOSE: This study examined the efficacy of an interferential current (IFC) treatment on the improvement of pain, disability, and quality of life in stroke patients with lumbago. METHODS: A double-blind, randomized clinical trial was conducted on 40 stroke patients with lumbago. The patients were allocated randomly into two groups: the IFC treatment group (n= 20) and the placebo treatment group (n= 20). The IFC group received 30 minutes of IFC treatment on the lumbar region, while the placebo group received IFC treatment but without real electrical stimulation. The intervention was administered five days a week for four weeks. The primary outcomes of pain intensity were measured using a visual analogue scale. The secondary measurements included the Barthel Index, Oswestry Disability Index (ODI), and health-related quality of life (HRQoL). RESULTS: The measurements were conducted before and after the two-week intervention period. Compared to the placebo treatment group, the IFC treatment group showed significantly greater improvement in the pain intensity (p<.05), ODI (p<.05), and SF-36 (p<.05) at the end of the intervention. No significant differences in the Barthel Index were found between the two groups. CONCLUSION: These findings show that an IFC treatment can improve pain, functional ability, and quality of life, highlighting the benefits of somatosensory stimulation from IFC in stroke patients with lumbago.