• Journal of Life Science
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• v.25 no.1
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• pp.113-120
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• 2015

Osteoporosis is a major bone disorder defined as having bone mineral density (BMD) of 2.5 standard deviations or more below the peak bone mass. Osteoporosis will increasingly be a major disorder that faces the aging mankind. It is the result of an imbalance in the bone remodeling system, where bone constantly undergoes a cycle of resorption by osteoclasts and formation by osteoblasts. Estrogen deficiency in women following menopause is identified as the predominant reason that causes disparity in this system. Current medical treatments for osteoporosis include hormone replacement therapy (HRT), biphosphonates, and teriparatide, but have various side effects that raise questions concerning their medical safety and practicality. Alternative treatments involving natural product sources are under study to find a safer therapy. Many natural sources including lactoferrin and isoflavones and numerous traditional herbal medicines exhibit anti-resorptive or anabolic effects on bone and thus show promises to provide therapeutic agents in treating osteoporosis. Unfortunately, the majority of natural product treatments are still in its preliminary stages to prove their efficacy even though the development pace of treatment for osteoporosis is astounding in the past few decades. Further progress in pre-clinical studies and the subsequent clinical studies will someday lead to a breakthrough that takes us another step forward in science.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.2B
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• pp.129-137
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• 2003

Multimedia streams, like MPEG continuously retrieve multimedia data because of their incessant playback. While these streams need an efficient support of kernel, the current buffer cache mechanism of Linux kernel such as Unix operating system was designed apt for small files, which is aperiodically requested as well as time uncritical. But, in case of continuous media, the CPU must enormously copy memory from kernel address space to user address space. This must lead to a large CPU overhead. This overhead both degrades system throughput and cannot guarantee QOS. In this paper, we have designed and implemented two memory copy reduction schemes in Linux kernel, direct I/O and one copy. The direct I/O skips the buffer cache layer of Linux kernel and results in dramatic reduction of CPU memory copy overhead. And, the one copy provides a fast disk-to-network data path without copying to user address space. The experimental results show considerable reduction of CPU overhead and throughput improvements.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2485-2490
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• 2016

The liver is one of the most common sites of cancer in the world, hepatocellular carcinoma (HCC) predominating. HCC is the sixth most common cancer and the third leading cause of cancer related death overall. Hepatitis C is a major risk factor and HCV is a rapid spreading virus which has become a problem globally, including in Pakistan. Interferon alpha therapy is used against HCV disease to regulate cell reproduction and to boost the immune system. In minute amounts interferon alpha is produced naturally by the immune system in HCV patients in response to hepatitis C virus and binds to receptors in the target cells and starts transcription of 20-30 genes due to which it develops an antiviral influence. Interferon is also administered artificially to overcome HCV disease and remove the biological effect of the virus from the infected site. The use of interferon or Peg-IFN plus Ribavirin treatment is also associated with adverse effects on body. For the current study, a convenient sample of 156 HCV positive patients of both males and females were taken. To collect blood CP and ALT, a reduction of level data and other important information were collected from the patients at regular intervals. Findings were 11.4 % in the red blood cells (RBC), 9.64 % in the total leukocyte count (WBC), 8.4 % in the hemoglobin levels (HB), 30.3 % in the platelet (Plt) count in both sexes. There was significant reduction in ALT levels due to Pegylated interferon plus ribavirin therapy. Hence strict haemotological monitoring of blood CP and ALT levels is necessary at regular intervals to reduce severe side effects which may lead to morbidity and mortality.

• Journal of Engineering Education Research
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• v.7 no.2
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• pp.40-50
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• 2004

To keep pace with rapidly changing social and technological trends, the Department of Mechanical and System Design Engineering at Hongik University is in the process of updating teaching materials and learning methodologies while evaluating/revising our existing curriculum. In order to be better apprised of the employment needs and student aspirations, we have conducted three separate but related surveys by targeting experienced professionals and managers, alumni working in industries as practising engineers, and our current students. The surveys have furnished us with valuable insights that, we hope, will lead to a new curriculum and learning methods more in tune with needs of our students as well as their future employers. Among other findings, the analysis of the survey responses points towards expansion of integrated laboratory and design experiences, cultivation of improved written and oral communication capabilities involving individual and team efforts, and development of interdisciplinary courses encompassing related fields of engineering as well as emerging fields such as nano and information technologies.

• Journal of the Korean Geographical Society
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• v.32 no.4
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• pp.575-584
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• 1997

So how can we develop balanced growth in our country? The national development policy of our hovemment over the past 30 years has lead to the corpulence of Seoul at the expense of the provinces. Now ironically there are policy measures introduced to control the over-expansion of Seoul. Yet the current hardware stategies to control the center requires an additional sofware stategy to create a nationwide balance for development. The Regional Elite Quota System is one such sofware stategy which can adjust the unbalanced distribution of gifted student across the national university deucation system. One obvious solution that should be utillzed is the incredible enthusiasm for high education that exists in this country, perhaps the highest in the world. This has been the backbone of our national development and should be hamessed as a catalyst to produce more balanced national growth.

• Journal of Korean Library and Information Science Society
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• v.46 no.3
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• pp.71-88
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• 2015

It had been said that reading education in Japan has a goal to 'Lead children's character to a desirable direction'. Since the 2000s, Japan's reading activity was directly linked with an education program to improve children's education ability. These movements for reading in Japan is made more concrete by the 'Promotion Act on Children's Reading Activities'. For improving the reading skills of the younger generation in Japan, cooperation among homes, regions, and schools is needed. As a result, Japan has an opportunity to build an educational infrastructure for reading support services. The library has also been given an enhanced role as a learning commons. In this background, this study tried to analyze the current state of Japan's reading instruction qualification system, and show their efforts to foster reading specialists for improving the reading skills of the younger generation. This will generate the momentum needed to have the library evolve into learning commons.

• The Journal of Engineering Geology
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• v.20 no.2
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• pp.213-220
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• 2010

The permeability characterization on the natural barrier for deep geological disposal of radioactive waste is very critical to evaluate total safety and performance assessment of disposal site. However, the confidence level in using previous hydraulic testing equipments consist of simple components to estimate rock mass permeability is not high enough to reflect in situ condition. The purpose of this research is to establish an advanced hydraulic testing equipment, which is applicable to deep borehole (up to 1,000 m), through the improvement of technical problems of previous packer systems. Especially, the straddle packer hydraulic testing equipment was designed to adopt both the hydraulic downhole shut-in valve(H-DHSIV) to minimize the wellbore storage effect and the real time data acquisition system to measure the pressure changes of test interval including its upper and lower parts. The results from this research lead to not only improve current technical level in the field of hydraulic testing but also provide important information to radioactive waste disposal technology development and site characterization project.

• The Journal of the Korea Contents Association
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• v.10 no.10
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• pp.152-160
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• 2010

Modern comics find their roots in caricatures, which have a basic element of comics as a combination of wrings and drawings. In three East Asian countries, new media, comics have been developed by joining modern arts and cartoons which is a news form of western comics. As modern comics have evolved according to situations of the three countries, they expand from the satire on the system, foreign invasions, and internal corruption to the enlightenment of the people. However, the criticism on the system lead to the oppression, and the imperialism in East Asian countries enforce the agitation, war engagement, propaganda of the colonialism on the comics. Current East Asian comics have been occupying the largest part in the world comics, and have their roots in the modern comics. So it is meaningful to investigate the characteristic of modern East Asian comics.

• Journal of Korea Technology Innovation Society
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• v.12 no.3
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• pp.614-637
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• 2009

To enhance the efficiency of national R&D programs, it is the most important thing to establish the optimized evaluation system. This is because the distorted evaluation could be an obstacle to select the best suited research team and lead the desirable research result. In current evaluation process of national R&D program, it is the most frequently used method for eliminating an evaluator's biased view to exclude both the maximum and minimum scores. However, there are several limitations in this stereotype method. Therefore, this study analyzes some real cases to derive the problems from the stereotype method and then recommends the complementary alternatives which can enhance the reliability of the evaluation system for national R&D programs. The results acquired from this study seem to be helpful to increase the agreement of the applicants on the evaluation results and ultimately to maximize the efficiency of national R&D program. In addition, they can be applied to various field with respect to the methodology for ranking decision.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.12B
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• pp.735-742
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• 2007

We propose an effective packet marking algorithm for video streaming in DiffServ network. Because legacy packet markers such as srTCM(single rate three color marker) cannot distinguish the importance of packet, these markers can cause quality degradation of streaming during the network congestion period. Recently proposed TMS (Two Marker System) [4] shows effectiveness in such scenario that video streaming service is struggling with other types of service traffic. However, if many video streaming services co-exist in DiffServ network and result in competition among themselves, then both legacy packet markers and even TMS cannot prevent drastic streaming quality degradation. To cope with this, we suggest A-TCPM (Adaptive time sliding window Three Color Marker) algorithm. In this algorithm, an A-TCPM module decides the color of a racket based upon the probability which is lead by current channel status and frame importance ratio. Simulation results show that proposed A-TCPM algorithm can enhance streaming service quality especially when overbooked video streaming sessions struggle with themselves.