• Title/Summary/Keyword: current body size

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The Biostability and Cancer Effect of PLGA Nanoparticles with Different Charges (전하가 다른 PLGA 나노 입자의 생체 안정성 및 암세포에 미치는 영향)

  • Kim, Inwoo;Park, Seungbin;Ji, Yuhyun;Park, Sanghyo;Key, Jaehong
    • Journal of Biomedical Engineering Research
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    • v.39 no.3
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    • pp.140-145
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    • 2018
  • Cancer is a major burden of human disease worldwide. Current chemotherapy has severe side effects because the drugs affect whole body nonspecifically. In addition, the drugs to reach cancer cells are very limited. Over the last two decades, Drug Delivery System (DDS) using nanoparticles has suggested promising results to improve current limitations. In this study, we prepared PLGA nanoparticles with different charge properties and observed their stability and internalization effect to cancer cells. Results using Dynamic Light Scattering (DLS) and Fourier Transform Infrared Spectroscopy (FTIR) confirmed the size and chemical composition of the nanoparticles. The stability of the nanoparticles in pH buffers were variable depending on charge properties. The nanoparticles showed different cytotoxicity and internalization effects to MCF-7 human breast cancer cells. In conclusion, we demonstrated the importance of delicately engineered nanoparticles for better DDS in cancer.

A Comparative Study on the Sizing Systems of the Infants and Children's Swim-suit (유유아 수영복의 치수체계 비교 연구)

  • Yi Kyong-Hwa;Jung Hae Sun
    • Journal of the Korean Society of Clothing and Textiles
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    • v.29 no.1 s.139
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    • pp.1-12
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    • 2005
  • This study was to suggest a feasible sizing system of infants and children's swim-suits. The basic body dimensions were selected after surveying the swimsuit manufacturers. The control dimensions and the secondary dimensions were taken from the 1997 National Anthropometric Survey data for the establishment of the sizing system. While in the current market swimsuit sizes were generally measured by the hip circumference for boys, and the bust and hip circumference for girls, the height was selected in this study as the control dimension because the height is well recognized by the customers and the KS standards specify the height to be the control dimension for infant's and children's wear. In the new sizing system of this study, the height was a control dimension, and hip was selected as a secondary dimension for boys. and bust and hip were selected as secondary dimensions for girls. Conclusively, in this study we suggest 12 sizes in case of 5cm height interval by the KS sizing system and 7 sizes in case of loom height interval by the current market sizing system, based on the height as a control dimension, for a standard swim-suit sizing system for infants and children.

The Evaluation on Welding Qualities by Gun Press Force Patterns in the RSW (Resistance Spot Welding) Process using Servo Gun (서보건을 이용한 저항 점용접 공정에서의 가압력 패턴에 의한 용접품질 평가)

  • 박영제;조형석;박지환
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.252-252
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    • 2000
  • The Resistance Spot Welding (RSW) has been considered as an inherently safe and reliable method far joining metals, and has been widely employed, especially in automobile body assembly shops, as a manufacturing process. In recent years, the requirement for more sophisticated quality control procedures has considerably grown in the mass production industries. The object of the application of servo control to spot welding gun is the improvement of quality control in the spot welding, one of conventional industrial areas. The important factors affecting welding qualities (shear strength, nuggest size, indentation depth) are welding current, welding time, and gun press force. Welding current and welding time are controlled by welding timer. But, the conventional welding guns using compressed air are out of control in changing gun press forces in welding process. In this paper, a servo gun welding system having a AC servo motor and a PC control system is presented. The main object of this paper is to estimate the influence of gun press force changes in the welding process (press time -> welding time -> hold time) to welding qualities, and to evaluate welding qualities in real time, by recognizing the patterns of gun press forces changed in the welding process and comparing with the standard patterns.

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The Effects of Design Parameter to Interrupt Optimally for High Voltage CL Fuse (고압한류퓨즈의 최적 차단을 위한 설계변수의 영향)

  • Lee, Se-Hyeon;Han, Sang-Ok
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.48 no.3
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    • pp.185-191
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    • 1999
  • The fuse used in the high voltage distribution line often fails due to the active ionization caused by the strong electric field at fuse terminal. To suppress the ionization at the high voltage and high capacity current limiting fuse, the particle size and compactness of silica sand, the design, length, notch number and material of element, the diameter and length of fuse body must be considered carefully. However, these are not many proper which is treated with the inherent interrupting characteristics from many parameters at present. Because of these reasons, time and effort are needed to develop the new type fuse by the fuse designers in relation with the inherent characteristics from each of parameters. In this paper we choose 7 parameters with weight value based on study and experimentation and analyzed the characteristics of arcing period. In addition, we proposed the experimental method to experimentation and analyzed the characteristics of arcing period. In addition, we proposed the experimental method to extract the optimal design parameters with minimal effort as related the mutual effect from each of the parameters.

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The Current Distribution and Habitat Preferences of Hibernating Myotis formosus in Korea

  • Kim, Sun-Sook;Choi, Yu-Seong;Kim, Bong-Hyeon;Yoo, Jeong-Chil
    • Journal of Ecology and Environment
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    • v.32 no.3
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    • pp.191-195
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    • 2009
  • We monitored 38 hibernation sites of Myotis formosus in South Korea and recorded the number of bats occupying each site and assessed the micro-climate at the sites during four winters from 2005 to 2009 at. The mean rock temperature of the bat roosting sites was $13.2{\pm}1.4^{\circ}C$ and the mean body temperature of the hibernating bats was $13.3{\pm}1.3^{\circ}C$. The number of hibernating bats was negatively related to the size of the entrance and positively related to the minimum ambient temperature and humidity in the site interior. More bats hibernated in roosts with smaller entrances and higher minimum ambient temperatures, and more bats selected sites presenting a narrow temperature range. This study showed that the internal environments of hibernacula of M. formosus were highly stable despite dramatic variation in the external environment.

Efficiency and EMF Safety Analysis of Wireless Power Transfer System Using Standard Human Model (표준화된 인체모델을 이용한 공진형 무선전력전송 시스템의 효율 변화 및 인체 안전성 분석)

  • Shin, Hansu;Byun, Jin-Kyu
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.27 no.11
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    • pp.96-103
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    • 2013
  • In this paper, resonant wireless power transfer systems are designed with double loop resonant coils for the resonant frequency of 150kHz. The transfer efficiency characteristics is analyzed according to the coil size, and the distance and misalignment between the coils. Then the change in efficiency is investigated when a human model is located between the resonant coils using the homogeneous human phantom of IEC-62311 standard. Also, in order to assess the safety of the wireless power transfer system, the induced current density inside the human model is calculated when it is exposed to the magnetic field of a plane wave and resonant coil. Then, the results are compared with the exposure limits in the EMF (electromagnetic field) safety guidelines.

A Study on the Stimulus control of L-$\alpha$-DLPC Organic Monolayers

  • Song, Jin-Won;Lee, Kyung-Sup
    • 제어로봇시스템학회:학술대회논문집
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    • 2001.10a
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    • pp.181.3-181
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    • 2001
  • Recently, the study on development of electrical and electronic device is done to get miniature, high degrees of integration and efficiency by using inorganic materials. the study of Langmuir-Boldgett(LB) method that uses organic materials because of the limitation for the ultrasmall size. In this paper, to do research for medical artificial organs as well as principal parts living body thin film application, electrical properties of L-$\alpha$-DLPC Langmuir(L) films were investigated a displacement current measuring technique with pressure stimulation. We give pressure stimulation into organic thin films and then manufacture a device under the accumulation condition that the state surface pressure is 20[mN/m]. LB layers of L-$\alpha$-DLPC deposited by LB method ...

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A Novel Process for Fabricating High Density Trench MOSFETs for DC-DC Converters

  • Kim, Jong-Dae;Roh, Tae-Moon;Kim, Sang-Gi;Park, Il-Yong;Yang, Yil-Sulk;Lee, Dae-Woo;Koo, Jin-Gun;Cho, Kyoung-Ik;Kang, Young-Il
    • ETRI Journal
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    • v.24 no.5
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    • pp.333-340
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    • 2002
  • We propose a new process technique for fabricating very high-density trench MOSFETs using 3 mask layers with oxide spacers and a self-aligned technique. This technique reduces the device size in trench width, source, and p-body region with a resulting increase in cell density and current driving capability as well as cost-effective production capability. We were able to obtain a higher breakdown voltage with uniform oxide grown along the trench surface. The channel density of the trench DMOSFET with a cell pitch of 2.3-2.4 ${\mu}m$ was 100 Mcell/$in^2$ and a specific on-resistance of 0.41 $m{\Omega}{\cdot}cm^2$ was obtained under a blocking voltage of 43 V.

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Effect of Organic Lubricant Film on Various Properties of Galvannealed Steel Sheets (합금화용융아연도금강판의 품질특성에 미치는 유기윤활피막의 영향)

  • 김영근
    • Journal of the Korean institute of surface engineering
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    • v.36 no.2
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    • pp.176-184
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    • 2003
  • New lubricant film of organic and inorganic composite resin was developed to improve the press formability of galvannealed steel sheets (GA) for automotive body panels. The frictional coefficient of lubricant GA steel sheets is about 20% superior to that of uncoated GA. The current range of spot welding of lubricant GA is similar to that of the uncoated GA, but the burning trace of spot welding is inferior to that of the uncoated GA in the oiling condition. The alkaline degreasability of lubricant GA shows 100% in alkaline degreasing condition of automotive company. The size and shape of the phosphated coating layer are similar to those of the uncoated GA sheet. The powdering property of the lubricant GA gives rise to 20∼50% improved property compared with the uncoated GA sheet.

Dynamic Analysis for 1 inch micro-drive (1인치 마이크로 드라이브의 동특성 해석)

  • 황창호;박경수;전정일;박영필;박노철
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2003.05a
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    • pp.592-597
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    • 2003
  • To solve a problem of micro drive due to small size and portability, it is necessary to understand and to investigate micro drive widely ,deeply. So, we performed modal analysis of suspension of micro drive, and load/unload experiment for Input current to VCM coil and disk speed. To determine the effect of ramp profile, curve fitting of lateral speed is performed with equation of speed. The results indicate that small load/unload speeds decrease the number of head/disk contacts, and during unloading process, low disk speed increase the number of head/disk contacts.

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