• 대한한방내과학회지
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• 제19권1호
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• pp.505-523
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• 1998

Aroma therpay in the western classical medicine is compared with the mechanistic paradigm of Newton physics which is the foundation of western modern medicine. It is the therapy whose basic principle is very similar to the basic concepts of oriental medicine lasting thousands of years. We know that parts of their therapies are explained by Yin-Yan and five elements in Oriental Medicine. In the modern western medicine, as preventive medicine is becoming more and more important and moreover, health promotion and self healing care is being emphasized, Maintenanayce which is the oriental preventive medicine, acts in concert with the concept of New Age of Science and provides a way for the Oriental Medicine of the future. The health promotion and self healing care is similar to the thought of Maintenanayce in Oriental Medicine. Oriental Medicine has provided the concept of preventive ehaling care for a long time and built the foundation of the department of Maintenanayce. Among these method of Preservation of Health, We could find that of using fragrance throuth the several references. By comparing the department of Maintenanayce in oriental preventive medicine with the books and papers about aroma therapy, used in the fields of naturalpathy medicine, alternative medicine, and complementary medicine in the west, and by analyzing them, centering around references, to see whether they are reasonable and corresponding, the following conclusions have been reached. 1. We could see that aroma therapy of oriental preventive medicine could be applied to the fields of health promotion and self healing cure, recently appearing in the world of health medicine, as a modern way of Preservation of Health(養生). 2. We could see that western traditional aroma therapy take important position in alternative medicine and complementary medicine, and it could be developed as the transitional field of medical cure for the interchange between western and eastern medicine. 3. We could see that aroma therapy is not totally unknown therapy and there is some points of similarity in the traditional references of oriental medicine. Also, it is considered that the aroma therapy has a possibility of coming the front as an general therapy among various therapies. 4. aroma therapy will be actively applied to many fields such as oriental psychiatry, internal medicine of the respiratory system, pediatrics, oriental nursing, oriental dermatologic beauty, and preventive medicine. Therefore, we have a view that the combination between aroma therapy and oriental medicine will be fairly valuable to study as the general and transtional middle step on which it will prepare the situation of oriental medicine's reimportation from the west and we establish a bridgehead to export the oriental medicine.

• 대한치과보철학회지
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• 제46권5호
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• pp.511-519
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• 2008

연구목적: 본 연구의 목적은 자가중합 또는 이중중합을 위한 활성제가 포함된 상아질 접착제에서 활성제의 사용 유무가 자가중합 복합레진과 상아질 접착제간의 전단결합강도에 미치는 영향을 평가하는 것이다. 연구 재료 및 방법: 실험을 위하여 우식 및 충전물이 없는 건전한 대구치 50개를 주문제작한 아크릴릭 레진블록에 포매한 후, 모델 트리머로 연마하여 평활한 상아질면을 만든 후, 600grit 실리콘 카바이드 페이퍼로 연마하고 증류수에 보관하였다. 50개의 시편을 10개씩 5개 군으로 나눈 후, 상아질 접착제를 제조사의 지시대로 도포한 후, 플라스틱 주형을 이용하여 자가중합 복합레진 (Luxacore)을 접착시켰다. 상아질 접착제는 One-Step (OS군), Prime&Bond NT, AdheSE를 이용하였는데 Prime&Bond NT와 AdheSE는 단독으로 사용한 군 (PB군, AS군)과 활성제를 같이 사용한 군 (PBA군, ASA군)으로 다시 나누었다. 증류수에 24시간 보관 후, 인스트론 만능시험기를 사용하여 시편에 1 mm/min의 전단속도로 하중을 가하여 시편이 분리되는 최대 하중을 측정한 뒤, 단위 면적 당 결합강도 (MPa)로 환산하여 One-way ANOVA를 이용하여 비교, 분석하고 5% 유의수준에서 Tukey HSD 검정을 이용하여 분석하였다. 결과: 각 군의 전단결합강도의 평균을 보면, OS군이 18.6 MPa로 가장 높았고 그 다음이 PBA군 (10.3 MPa)과 ASA군 (10.2 MPa)이었고, PB군과 AS군이 각각 5.9 MPa, 6.0 MPa로 가장 낮은 전단결합강도를 나타내었다. 결론: 본 실험을 통해 Prime&Bond NT와 AdheSE에서 활성제를 같이 사용한 경우, 활성제를 사용하지 않은 경우보다 전단결합강도가 높아짐을 알 수 있었지만, 활성제가 포함되어 있지 않은 One-Step보다는 낮은 수치였다.

• 대한지하수환경학회지
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• 제4권3호
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• pp.144-152
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• 1997

본 연구에서는 비포화흐름을 해석하는데 있어 기초자료가 되는 물보유함수를 추정하기 위하여 SUS, KUS 등 두가지 국내토양에 대한 물보유함수를 체적기압판추출장치를 이용하여 측정하였다. 체적기 압판추출장치를 사용할 때 압력을 점차적으로 증가하면서 흙시료로 배출되는 물의 양을 정확히 측정한다. 또한 압력이 점차적으로 줄어들 때 흙에 유입되는 물의 양을 정확히 측정한다. 실험결과 젖음 또는 마름과정에 따라 물보유함수가 차이가 나는 이력현상이 발생하였다. 대표적인 물보유함수인 Gardner식, Brooks-Corey식 그리고 van Genuchten식의 실측치에 대한 매개변수 추정을 통하여 그 물리적 의미와 각 토양시료별 매개변수 값을 구하였다. 그 결과 Gardner식, Brooks-Corey 그리고 van Genuchten의 매개변수는 공기유입값과 토양의 입경 크기에 관계 되는 변수임을 알 수 있었다. 결론적으로 van Genuchten식이 측정된 실험자료를 가장 정확하게 모의함을 알 수 있었다.

• Biomolecules & Therapeutics
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• 제23권2호
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• pp.141-148
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• 2015

Epithelial mesenchymal transition (EMT) is the first step in metastasis and implicated in the phenotype of cancer stem cells. Therefore, understanding and controlling EMT, are essential to the prevention and cure of metastasis. In the present study, we examined, by Western blot, reverse transcription polymerase chain reaction (RT-PCR), and confocal microscopy, the effects of cardamonin (CDN) on transforming growth factor-${\beta}1$ (TGF-${\beta}1$)-induced EMT of A549 lung adenocarcinoma cell lines. TGF-${\beta}1$ induced expression of N-cadherin and decreased expression of E-cadherin. CDN suppressed N-cadherin expression and restored E-cadherin expression. Further, TGF-${\beta}1$ induced migration and invasion of A549 cancer cells, which was suppressed by CDN. TGF-${\beta}1$ induced c-Jun N-terminal kinase (JNK) activation during EMT, but CDN blocked it. Protein serine/threonine phosphatase 2A (PP2A) expression in A549 cancer cells was reduced by TGF-${\beta}1$ but CDN restored it. The overall data suggested that CDN suppresses TGF-${\beta}1$-induced EMT via PP2A restoration, making it a potential new drug candidate that controls metastasis.

• 한국진공학회지
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• 제14권1호
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• pp.35-39
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• 2005

본 실험에서는 단위요소 사이에 채널을 갖는 Elementwise Patterned Stamp (이하 EPS)를 이용하여 싱글스탭 (single step)으로 4인치 웨이퍼를 임프린트 하는 공정을 수행하였다. 단위요소간의 간격이 3m인 EPS를 이용한 임프린트에서 50 - 100nm급의 패턴을 성공적으로 형성하였다. 그러나 임프린트 과정 중 EPS의 채널 부분에서 웨이퍼의 미소변형이 발생하여 단위요소의 미충전과 불균일한 잔여층이 형성되는 문제들이 발생하였다. 본 논문에서는 이러한 웨이퍼의 미소변형이 단위요소 충전과 패턴형성에 미치는 영향을 확인해 보기 위해 웨이퍼의 두께를 100 - 500㎛로 변화시켜가며 임프린트 실험을 수행하였고, 유한요소법(Finite Element Method, FEM)을 이용한 수치모사를 통하여 실험결과를 확인하였다. 또한 웨이퍼의 미소변형이 발생하는 또 다른 요인인 EPS의 채널 폭을 3mm, 2mm, 1mm로 변화시키며 수행한 수치모사를 통하여 안정된 임프린트 조건을 제시하였다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2006년도 춘계학술대회 논문집
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• pp.321-322
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• 2006

In many manufacturing processes such as web formation, manufacturing of paper and nonwoven, fabric weaving, etc., planar sheets are transported and at the same time appropriate tension is imposed. The input material rolled up on beams is fed by unwinding the beam and the processed is then taken up on beams by winding it. While processed, the planar sheets are thrown under the processing load of impulse form, which causes irregular thickness of the processed sheet. To improve the quality of the product, a dynamic model is needed and the dynamic characteristics is to be analyzed by simulation. This study shows that density variation dynamics of the in-process-sheet in the machine direction can be described at each moment of disturbing impacts in forms of difference equations, while the impacts and tension, the time-dependency of the material properties were taken into account. Simulation showed the most serious variation of the density occurred in the process starting phase. The starting velocity curve with step form showed the least variation of the density. As the time order of the function of the starting velocity cure becomes higher, the density variation gets greater.

• 공업화학
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• 제31권6호
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• pp.585-590
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• 2020

암(예: 폐암, 전립선암, 간암, 부신겉질샘암종 등)의 조기 진단은 치료비용, 생존율, 완치 여부를 결정짓는 아주 중요한 단계다. 현재의 암 진단 시스템(예: 조직검사, 컴퓨터단층쵤영, 양전자방출단층쵤영, 자기공명영상, 초음파촬영 등)은 고가의 장비를 사용하거나 훈련된 고급 인력만이 수행 가능하기 때문에 신속한 조기 진단에 적합하지 못하다. 국제 의과학 사회는 현장검사(point of care) 디바이스 개발을 통한 효과적인 질병 관리 시스템 개발을 지향하고 있으며, 다양한 분석법 기반의 디바이스가 개발되어왔다. 이 중에서도 측면 흐름 면역 크로마토그래피 분석법 스트립은 경제적인 비용, 짧은 검사 시간, 사용자의 쉬운 접근성 등의 많은 이점들이 있다. 본 논문에서는 LFIA 스트립의 최신 연구 동향을 바탕으로 암 진단 관점에서의 비색법 기반 LFIA 스트립의 연구 방향 및 잠재적 응용에 대해 논의하고자 한다.

• 대한소아치과학회지
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• 제44권4호
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• pp.419-426
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• 2017

맹출 장애 치료를 위해 교정력을 이용한 매복치의 맹출 유도를 시행하며, 이 과정 중 여러 원인에 의해 부착 실패가 일어날 수 있다. 이 연구의 목적은 산부식 레진 접착 시스템과 자가 산부식 접착 시스템을 이용하여 전단 결합 강도를 평가해보고, 접착 과정 중, 프라이머 도포 후 광중합 단계를 생략하여 시간 절약이 전단 결합 강도에 미치는 영향을 평가해보고자 하였다. 발거된 사람의 상악 전치부 40개 치아를 대상으로 I군과 II군은 산부식 후 프라이머로 Transbond$^{TM}$ XT Light cure Adhesive primer를 적용 하였으며 III군과 IV군은 Transbond$^{TM}$ Plus Self Etching primer을 적용 하였다. I군과 III군은 제조사의 지시 사항대로, II군과 IV군은 접착제 도포 후 광중합 단계를 줄여 부착을 시행하였다. 그 후 전단결합강도와 접착제 잔류 지수(Adhesive Remnant Index, ARI)를 이용하여 기록하였다. 전단결합강도는 I군, II군, III군 그리고 IV군 순으로 컸으며 대조군인 I군과 실험군 간에만 유의차가 있었다(p < 0.05). ARI 지수는 I군, III군, IV군 그리고 II군 순으로 대조군에서 치면과 레진 사이의 결합력이 컸다. 대조군이 유의하게 전단결합강도가 높았으나 다른 군에서도 임상적으로 유용한 전단결합강도를 가진다.

• 대한치과보철학회지
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• 제41권3호
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• pp.319-324
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• 2003

Statement of problem. Adhesives in dentistry playa major role in the success of restorative treatments. In the treatment of all ceramic restoration it is needed to find the adequate bond strength between enamel and dentin. Purpose. The purpose of this study was to evaluate shear bond strength of resin cement bonded to extracted human uncut enamel, cut enamel, and dentin in vitro. Material and methods. Ten freshly extracted anterior teeth without any previous restorative treatments were chosen. The extracted teeth were embedded in PMMA cold acrylic in the shape of a cylinder, 25 mm in diameter by 25 mm in height. The bonding system used was as follow: Uni-Etch (32% phosphoric acid), One-Step adhesive, Duolink resin cement. The specimens were acid etched and rinsed with water. Two layers of One-Step adhesive were coated with a disposable brush on the uncut enamel. VIP curing light at $500mV/cm^2$ was used to cure the adhesive. For cut enamel shear bond test, the specimen used for uncut enamel was further reduced approximately $0.3{\sim}0.5mm$ using a laminate preparation diamond bur (0.3 mm in depth). The specimens were subsequently treated with 320-grit SiC paper followed by 600-grit SiC paper and cleaned with distilled water. The bonding procedure on the cut enamel was same as uncut enamel bonding procedure. For dentin bonding test, the specimen used for cut enamel was further reduced approximately $0.5mm{\sim}1.0mm$ using a laminate preparation diamond bur (0.5 mm in depth of diamond cutting). The amount of reduction was evaluated with the silicone mold. The specimens were subsequently treated with 320-grit SiC paper followed by 600-grit silicon carbon paper and cleaned in distilled water. The bonding procedure on the dentin was same as uncut enamel bonding procedure. All samples were mounted and secured on the Ultradent shear bond test sample holder, and Ultradent restricted shear bond testing device was used with Universal Instron machine until fracture. Analysis of variance (ANOVA) test was performed comparing the result at P<0.05. Multiple comparison (Tukey) was used to compare each groups. Result. The result showed that the mean value in shear bond strength of resin cement bonded to uncut enamel, cut enamel and dentin were 27.04 Mpa, 30.25 Mpa and 26.39 Mpa with respect. Conclusion. Within the limitation of this study, the mean value of the shear bond strength of cut enamel was higher than those of uncut enamel or dentin. However there existed no statistical differences between three different human dentition substrates due to increased adhesive characteristics.

• 한국치위생학회지
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• 제6권4호
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• pp.387-402
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• 2006

This research carried out a survey for 569 students in a junior college of jeollanamdo to provide a needful basic data in developing suitable health promotion program and creating a direction of the oral hygiene education process to intial adult population after holding the oral cavity health action and a affecting factors to it. A collected data obtained the following conclusion. According to school grade, a difference of action factor is Chi-square and Pearson's correlation coeficient in actionfactor and acknowledgement-perception factor and a step-by-step recurrence analysis processed a related factor of the oral health action. 1. A related action factor of the oral health appeared meaningful difference of the oral cavity medical examination, the oral cavity clean device use or not, dental surgery prevention cure or not among the third grade who had the most experience of the oral hygiene education within one year recently. 2. A significant of the oral cavity health acknowledged and perceived and a concern of the oral cavity health, acknowledged the oral cavity health state distribution are the highest in the third grade. 3. According to monthly income, a large income is higher than a small income about self-effects in a relation between the oral cavity health action and acknowledgement-perception factor. the average of a large income is 30.59(${\pm}5.79$). The obstacle of the oral cavity health action is 12.51(${\pm}3.19$). a large income is highest. according to school career, under middle school layer obtained the highest average 16.33(${\pm}3.53$). according to a school year, acknowledge-perception factor of the oral cavity health control of the third grade is the highest(38.81(${\pm}6.25$). 4. In mutual relation between acknowledge-perception factor and the oral cavity health action, a variable constants of meaningful mutual relation are the oral cavity health perception, self-effects, the oral cavity health action obstacle, the oral cavity health action benefit, the oral health action control, aggressive. and they are self-effects, the oral cavity health action in the oral cavity health perception. A significant of the oral cavity health and the oral cavity health action obstacle are the oral cavity health action benefit and the oral cavity health action control. 5. The affecting factors to the oral health action are self-effects, action factor, acknowledged the oral health control.