• IMMUNE NETWORK
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• v.6 no.1
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• pp.27-32
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• 2006

Background: Chronic inflammation in the brain has known to be associated with the development of a various neurological diseases including dementia. In general, the characteristic of neuro-inflammation is the activated microglia over the brain where the pathogenesis occurs. Pro-inflammatory repertoires, interleukin-1${\beta}$ (IL-1${\beta}$) and nitric oxide (NO), are the main causes of neuro-degenerative disease, particularly in Alzheimer's disease (AD) which is caused by neuronal destruction. Those pro-inflammatory repertoires may lead the brain to chronic inflammatory status, and thus we hypothesized that chronic inflammation would be inhibited when pro-inflammatory repertoires are to be well controlled by inactivating the signal transduction associated with inflammation. Methods: In the present study, we examined whether biphenyl dimethyl dicarboxylate (DDB), an active compound from Schizandra chinensis Baillon, inhibits the NO production by a direct method using Griess reagent and by RT-PCR in the gene expression of inducible nitric oxide synthase (iNOS) and IL-1${\beta}$. Western blots were also used for the analysis of NF-${\kappa}B$ and I${\kappa}B$. Results: In the study, we found that DDB effectively inhibited IL-1${\beta}$ as well as NO production in BV-2 microglial cell, and the translocation of NF-${\kappa}B$ was comparably inhibited in the presence of DDB comparing those to the positive control, lipopolysaccharide. Conclusion: The data suggested that the DDB from Schizandra chinensis Baillon may play an effective role in inhibiting the pro-inflammatory repertoires which may cause neurodegeneration and the results imply that the compound suppresses a cue signal of the microglial activation which can induce the brain pathogenesis such as Alzheimer's disease.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.3
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• pp.96-107
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• 2020

This study aimed to identify the associated factors of protective behaviors for radiation exposure among some radiology technologists using the Health Belief Model. The subjects of the study were 541 radiology technologists working at hospitals or clinics in Honam Province. Using the SPSS version 18.0 program, data were analyzed using a t-test, ANOVA, Pearson's correlation analysis, and hierarchical multiple logistic regression analysis. To modify the factors, the performance of subjects who had a higher level of education and nuclear medicine rooms were higher than those who worked in simple radiography rooms. The radiation protective behaviors performance of the subjects who had more exercise, medium-level stress, and worked in higher-quality protection facilities was higher. Regarding the personal perceptions, the cues to action (β=.292, p=.0001), and perceived seriousness (β =.075, p=.010) were factors that had effects on the performance of radiation protection behaviors. Regarding the likelihood of action, the benefits (β=.168, p<.0001), self-efficacy (β=.148, p=.007), and the performance of protective behaviors were higher. In conclusion, protection education as a cue to action should be provided to stimulate protective behaviors, and the benefits of protective behaviors should be emphasized. To increase the performance of protection behaviors, self-efficacy should be enhanced, and the subjects are offered appropriate information that helps perceive seriousness.

• Journal of the Korean Society for Library and Information Science
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• v.48 no.1
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• pp.53-73
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• 2014

Given that emotion-based computing environment has grown recently, it is necessary to focus on emotional access and use of multimedia resources including images. The purpose of this study aims to identify the visual cues for emotion in images. In order to achieve it, this study selected five basic emotions such as love, happiness, sadness, fear, and anger and interviewed twenty participants to demonstrate the visual cues for emotions. A total of 620 visual cues mentioned by participants were collected from the interview results and coded according to five categories and 18 sub-categories for visual cues. Findings of this study showed that facial expressions, actions / behaviors, and syntactic features were found to be significant in terms of perceiving a specific emotion of the image. An individual emotion from visual cues demonstrated distinctive characteristics. The emotion of love showed a higher relation with visual cues such as actions and behaviors, and the happy emotion is substantially related to facial expressions. In addition, the sad emotion was found to be perceived primarily through actions and behaviors and the fear emotion is perceived considerably through facial expressions. The anger emotion is highly related to syntactic features such as lines, shapes, and sizes. Findings of this study implicated that emotional indexing could be effective when content-based features were considered in combination with concept-based features.

• Applied Microscopy
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• v.41 no.2
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• pp.123-128
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• 2011

The micropyles on the prefertilized and artificial fertilized eggs of Epinephelus fasciatus were investigated using scanning electron microscope (SEM). The micropyles ($6.6{\pm}0.41\;{\mu}m$) of E. fasciatus eggs were found in the animal pole and theirs shape were observed as a flat crateriform of cylindrical shape. The micropylar vestibule arranged by 6~7 thickened spiral annuli on the ridge and contributed to differentiate and form fertilization cone for blocking to polyspermy by presenting swollen vestibule structure. As E. fasciatus eggs was pelagic, so chorionic surface was an uneven structures such as circular and fillar form nodules. Especially, various pores (0.15~0.55 ${\mu}m$, 230~270 pores) distributed at the only around micropyles, those pores radiately exhibited regular projection structures showing gill filament-shape. These ultrastructural characters of E. fasciatus eggs can be utilized in a taxonomical cue of grouper species.

• Science of Emotion and Sensibility
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• v.22 no.4
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• pp.75-84
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• 2019

Addicts pay more attention to addiction-related cues, such as substance or behavior. And increased attention to these cues is associated with craving. Methamphetamine is the most abused drug among domestic drug offenders, with continually increasing rates of recidivism. Of the total number of reported drug offenders in the last three years, 21.1 percent have been women. Even so, research on female drug offenders is inadequate, rendering policies and fundamental data for the development of psychotherapy programs insufficient. The present study intended to investigate whether female methamphetamine addicts displayed an attention bias towards drug cues. A dot probe task was conducted on 22 female methamphetamine addicts (addiction group) and 22 non-addicts (control group). The task allowed the correct response rates and correct reaction times of the participants to be calculated according to the positioning of the drug and neutral cues. The analysis results revealed that the control group displayed no difference in correct reaction rates and correct reaction times between the drug or neutral cues. While, the addiction group showed lower correct response rate and slower response time for drug cues in comparison to neutral cues. The results of this study are significant in that it identified the attention bias characteristics toward drug cues of female methamphetamine addicts who were disconnected from drugs.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.18 no.4
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• pp.37-42
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• 2018

With advancements in digital image production technology, the branch of stereoscopic image technology has also been undergoing active development. Accordingly, research and development on cutting-edge display products for mounting stereoscopic images are currently being pursued. There are various problems that can occur when viewing 3D images. Because viewers feel visual fatigue while perceiving the depth of the images provided via an artificial method, a negative human factor such as visual fatigue has become one of the most prominent concerns, especially as it is a factor that affects the ongoing maintenance of 3D images. Therefore, by identifying the factors affecting the depth of the graphic images provided in 2D images, and subsequently using this information to develop an image processing method, we conducted depth-related experiments and analysed them under the assumption that stereoscopic images could be reproduced without visual fatigue. Thus, we analysed the most significant factors related to depth and verified the interactions by performing depth-related factors-based ANOVA variance analysis by differentially applying the texture, colour temperature, and contrast ratio to graphic images. We determined the significance of the factors related to depth and proposed a method to improve depth based on an analysis of the results of the experiments conducted in this study.

• Phonetics and Speech Sciences
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• v.12 no.3
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• pp.41-53
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• 2020

A wh-phrase in an embedded sentence may have either an embedded or a matrix scope. Interpretation of a wh-phrase with a matrix scope has tended to be syntactically unacceptable unless the sentence reads with a wh-intonation. Previous studies have found two differences in prosodic characteristics between sentences with matrix and embedded scopes. Firstly, peak F0s in wh-phrases produced with an F0 compression wh-intonation are higher than those in indirect questions, and peak F0s in matrix verbs are lower than those in sentences with embedded scope. Secondly, a substantial F0 drop is found at the end of embedded sentences in indirect questions, whereas no F0 reduction at the same point is noticed in sentences with a matrix scope produced with a high plateau wh-intonation. However, these characteristics were not found in our experiment. This showed that a more compelling difference exists in the values obtained from subtraction between the peak F0s of each word (or a word plus an ending or case marker) and the F0s at the end of the word. Specifically, the gap between the peak F0 in a word composed with an embedded verb and the F0 at the end of the word, which is a complementizer in Korean, is large in embedded wh-scope sentences and low in matrix wh-scope sentences.

• The Korean Journal of Zoology
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• v.39 no.4
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• pp.337-351
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• 1996

Melatonin Is a multifunctional hormone secreted from the pineal gland in the middle of cerebrum and cerebellum. Its synthesis and release reflect photopedod;Photopedod is a yearly predictable ambient factor that most animals utilize as an environmental cue for maximum survival. Hamsters maintaln reproductive activity in summer during which day length exceeds night time. Upon the advent of autumnal equinox they undergo gonadal regression. The photoperiodic effects are prevented by removal of the pineal gland and restored by the timed repiacument of melatonin. The results suggest that melatonin constitutes part of control mechanism whereby environmental information is transduced to neuroendocrine signal responsIble for the functional integrity of the reproductive system. From the studies for the action site of melatonin following the treatment of photopedod or melatonin in the lesion of a spedflc portion of hypothalamus, suprachiasmatic nuclei and pars tuberalis are shown to be a consensus site for melatonIn. The action of melatonin. In the regulation of reproduction is largely unknown. It is mainly due to the lack of acute effect of melatonin on gonadotropin secretion. However, reduction of the gonadotropln release and augmentation of the hypothalamic gonadotropin-releasing hormone (GnRH) content by long-term treatment of melatonln Indicate that constant presence of melatonln may partidpate in the regulation of sexual activity via the GnRH neuronal system. The action mechanism by which melatonin exerts Its effect on GnRH neuron needs to be eluddated. The inability of opiold analogues to affect the reproductive hormones in sexually regressed animals by inhibftory photopedod and melatonin suggests that the opioldergic neuron may be a prime intervening mediator. Recent cloning of melatonin receptor will contribute to investigate its anatomical Identification and the action mechanism of melatonin on target tissues at the molecular level.

• Korean journal of applied entomology
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• v.24 no.2 s.63
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• pp.71-77
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• 1985

The male activity in Laspeyresia pomonella (L.) measured by an activity recording device in New York had two distinct peaks, the first peak at lights-off and the second one at ligts-on signal, under the defined conditions of temperature above $23^{\circ}C$ and light:dark (LD) 16:8 regime. The activity initiation of the first activity was observed four to six hours prior to the onset of scotophase and seened to be entraind by lights-off cue. Under the continuous photophase (LL) the activity period freeran with a period slightly greater than 24 hours, indicating that the rhythmicity is circadian The activity pattern was measured in eight different temperature conditions ranging from $11.3^{\circ}\;to\;30^{\circ}C$ under LD 16:8 regime. No activity was observed at $11.3^{\circ}C$ which seems to be temperature threshold for activity. The second peak of activity at lights-on signal disappeared at the temperature below $20^{\circ}C$ and the activity in scotophase was also suppressed at the temperature lower than $18^{\circ}C$. At the temperature range from $20^{\circ}\;to\;30^{\circ}C$, as temperature increased the second peak in the morning became larger and the activty in the scotophase was also increased. Because of the activity increase in the scotophase with rising temperature, the mean time of activity shifted towards the scotophase. The shift of the moth male activity period with the change of ambient temperature appears to be due to the suppression of activity under cool temperature (below $20^{\circ}C$) in scotophase.

• Journal of dental hygiene science
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• v.10 no.5
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• pp.329-334
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• 2010

This study was performed to identify the relationship between scaling behaviors and knowledge about scaling and oral health belief of worker, and to provide baseline data for developing industry oral health policy. The survey had conducted self-administered questionnaires by 326 workers in Gyeongsan and Yeongcheon areas in Gyeongbuk province. Their scaling behaviors, knowledge and oral health belief were measured. The results were as follow; The average score of knowledge about scaling was 6.44. The average oral health belief was 2.72. In detail, 'usefulness' was 3.24 as the highest and 'seriousness' was 2.25 as the lowest. The periodic scaling and scaling cycle were associated with 'seriousness' and 'barrier' as positive correlation(p<.05, .01). On the other hand, they were associated with knowledge and 'usefulness' as negative correlation(p<.01). Meanwhile, scaling motive showed positive correlation with 'cue of action'(p<.01), showed negative correlation with knowledge(p<.01). In the correlation between knowledge about scaling and oral health belief, knowledge showed negative correlation with 'barrier'(p<.01) and showed positive correlation with 'usefulness'(p<.01). Finally, we need to advertise and manage the importance of scaling politically and makes people do the voluntary scaling in six-month intervals in order to keep the periodontal health of worker.