• Journal of Acupuncture Research
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• 제35권4호
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• pp.226-237
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• 2018

Background: This study examined the characteristics and prognosis of patients admitted to the Dunsan Korean medicine hospital for treatment of herniated intervertebral disc (HIVD) or spinal stenosis with Miniscalpel needle therapy (MSN). Methods: Patients were admitted to the Dunsan Korean medicine hospital from January 01, 2016 to September 30, 2017 for the treatment of HIVD or spinal stenosis with MSN. Crossover analysis, Independent sample t test, one-way ANOVA, multiple linear regression analysis, and binary logistic regression analysis were performed. Results: Crossover analysis showed statistically significant differences in treatment methods according to gender, current pain according to the disease duration, satisfaction of MSN according to disease duration, treatment methods, and intention of re-treatment with MSN according to treatment methods. Independent t test and one-way ANOVA showed that there was a difference in current Numeric Rating Scale (NRS) according to disease duration, and difference between discharge and current NRS, and number of MSN according to disease. Multiple linear regression analysis showed that age, disease duration, and number of MSN affect discharge NRS, disease duration, and number of MSN affect current NRS, and Western medical treatment after MSN, discharge NRS, and current NRS affect satisfaction of MSN. Binary logistic regression analysis showed that discharge NRS affects current pain, and gender, discharge NRS, and treatment methods affect intention of re-treatment with MSN. Conclusion: Characteristics, prognosis, satisfaction and variables affecting prognosis of MSN were statistically significant, indicating that more systematic studies are required to further examine the effects of MSN on HIVD or spinal stenosis.

• Journal of Preventive Medicine and Public Health
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• 제34권3호
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• pp.253-261
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• 2001

Objectives : To evaluate the hypothesis that air pollution could increase emergency room visits for respiratory diseases, and if so, to quantify the strength of association between those. Methods : We compiled daily records of hospital emergency room visits for respiratory diseases in Seoul, from November 1. 1955 to October 31. 1996, by using medical utilization data of unscheduled visits. In addition, air quality and weather data for the same period was collected. And a case-crossover design was applied by adopting conditional logistic regression analysis to determine the relationship between air pollutants and emergency room visits for respiratory diseases. In particular, the control periods were chosen by a bidirectional paired matching technique 7, 14, and 21 days before and after the case periods. Results : Only ozone was associated with the increased number of emergency room visits for respiratory diseases. The relative risk according to a 30ppb increase of ozone concentration (24hr mean, lagged 1day) was 1.91(95% confidence interval = 1.78-2.05). Conclusion : There was a statistically significant association between the ambient ozone and daily emergency room visits for respiratory diseases.

• Journal of Preventive Medicine and Public Health
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• 제34권1호
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• pp.35-40
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• 2001

Objectives : To elucidate the transient effects on the risk of occupational injuries as acute events and establish so alternative proposal. Methods : The study population comprised a total of 302 workers randomly selected from applications for occupational injury compensation reported to the Inchon local labor office from January 1. 1999 to December 31. A case-crossover design, where each case serves its own control, was applied to this study. Through a telephone interview, workers provided useful data concerning five job related stressful events such as company transfer, work load change, overtime work, exchange duty, and work-part transfer. They were asked whether there were stressful events within a week of the occurrence of injury and the degree of stress. Exposure status from one year prior was used as control information. In the end, the data provided by 158 of selected persons was used for the analysis based on the quality of the data provided by the participants. A conditional logistic regression was used to discover the transient effects on the risk of occupational injuries as acute events. Results : The effects a company transfer and work load change on occupational injury was statistically significant on the risk of occupational Injuries as an acute event(RR=5.5, 95% CI=2.501-12.428; RR=3.1, 95% CI=1.963-5.017, respectively). Other stressful events were found to elevate the risk factor for the occurrence of occupational jujury, but were not significant. Conclusions : Our results suggested that transient stressful events elevated the risk factor for the occurrence of occupational injury.

• Advances in nano research
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• 제13권3호
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• pp.259-267
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• 2022

Two-dimensional (2D) transition metal carbides/nitrides or "MXenes" belong to a diverse-class of layered compounds, which offer composition- and electric-field-tunable electrical and physical properties. Although the majority of the MXenes, including Ti₃C₂T_x, are metallic, they typically show semiconductor-like behaviour in their percolated thin-film structure; this is also the most common structure used for fundamental studies and prototype device development of MXene. Magnetoconductance studies of thin-film MXenes are central to understanding their electronic transport properties and charge carrier dynamics, and also to evaluate their potential for spin-tronics and magnetoelectronics. Since MXenes are produced through solution processing, it is desirable to develop deposition strategies such as inkjet-printing to enable scale-up production with intricate structures/networks. Here, we systematically investigate the extrinsic negative magnetoconductance of inkjetprinted Ti₃C₂T_x MXene thin-films and report a crossover from weak anti-localization (WAL) to weak localization (WL) near 2.5K. The crossover from WAL to WL is consistent with strong, extrinsic, spin-orbit coupling, a key property for active control of spin currents in spin-orbitronic devices. From WAL/WL magnetoconductance analysis, we estimate that the printed MXene thin-film has a spin orbit coupling field of up to 0.84 T at 1.9 K. Our results and analyses offer a deeper understanding into microscopic charge carrier transport in Ti₃C₂T_x, revealing promising properties for printed, flexible, electronic and spinorbitronic device applications.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2010년도 추계학술발표대회
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• pp.478-481
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• 2010

본 논문에서는 경제학, 사회학, 수학 분야에서 수십년 전부터 연구해오던 죄수의 딜레마 게임의 협동진화에 대해 고찰해보고자 한다. 반복적 죄수의 딜레마 게임은 게임이론의 가장 기본적인 이론으로써, 사회적 상호작용, 경제활동, 국제관계 등 다양한 현상들을 모델링 하기 위한 하나의 방법이다. 그 중에 N명이 참가하는 반복적 죄수 딜레마 게임의 전략은 유전 알고리즘(Genetic Algorithms, GAs)을 통해 진화적으로 만들어 낼 수 있으며, 이 경우에 그 결과를 일반적인 내쉬 균형 이 아닌, 모든 개체들이 유전알고리즘을 통해 협동으로 수렴하도록 유도할 수 있다는 사실은 상당히 시사하는 바가 크다. 기존에 주로 연구되어오던 죄수의 딜레마 게임은 협동으로의 수렴과정에서 일반적으로 순위기반선택(Rank-based selection)과 1점 교배기법(1point crossover)을 사용한다. 그러나 순위기반선택은 모든 개체에 순위을 매겨야 하기 때문에, 개체수가 커질수록 성능이 저하되며, 1점 교배기법은 개체 값이 분산되어있을 경우, 최적해(Optimal solution)을 찾기 힘들다는 단점이 있어, 개체수가 많은 경우에 적용하기에는 비효율적이다. 본 논문에서는 토너먼트 선택기법(Tournament selection)과 자기 적응형 교배기법(Self-adaptive crossover)을 적용한 새로운 기법을 제안한다. 또한 기존 기법과 비교 실험을 통해 제안기법이 기존기법에 비해 평균 수렴시간과 수렴 횟수에서 뛰어난 성능을 보이고 있음을 확인하였다.

• 유통과학연구
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• 제16권1호
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• pp.59-71
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• 2018

Purpose - Recognizing the importance of small and medium enterprises and venture enterprises for the domestic economy, the purpose of the present study is to select factor termed export modes from among various export success strategies and factors that can help those enterprises secure export competitiveness in the world market to analyze the effects of export modes on the amounts of exports and periods until export after the foundation of those enterprises. Research design, data, and methodology - A structured questionnaire was used as a tool to derive the purpose of the study, and a questionnaire survey was conducted using a mobile survey technique that facilitated the distribution of questionnaire sheets and the collection of results. The main methodology used is crossover analysis, and the regression analysis technique was applied to verify the study results derived, thereby securing the reliability and validity of the final results derived. Results - Small and medium venture enterprises with shorter periods of time until the first export success after establishment adopted direct export modes more frequently, and those enterprises with larger amounts of the first export after establishment adopted direct export modes more frequently. The results of quantitative analysis, indicating that 66.1% of those enterprises with an export amount exceeding one billion won adopted direct export modes, can be said to support the foregoing. The crossover analysis results derived as such were reanalyzed using the PPML regression analysis technique to quantitatively identify that the amounts of the first export of enterprises that adopted direct export modes were larger than those of enterprises that adopted indirect export modes by 120%. Conclusions - The present study implies differentiated values in three aspects. First, the present study investigated and presented the export success factors and strategies of small and medium venture enterprises in a total of 14 countries in the Asian region, European region, North American region, African region, and South American region. Second, it intensively investigated five export modes to identify and verify that they were affecting the export success of small and medium venture enterprises. Third, based on the results of the investigation, the present study presented two marketing implications in the pragmatic aspect.

• Ocean and Polar Research
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• 제27권2호
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• pp.189-195
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• 2005

Several models predict large and potentially abrupt ocean circulation changes due to anthropogenic greenhouse-gas emissions. These circulation changes drive-in the models-considerable oceanic oxygen trend. A sound estimate of the observed oxygen trends can hence be a powerful tool to constrain predictions of future changes in oceanic deepwater formation, heat and carbon dioxide uptake. Estimating decadal scale oxygen trends is, however, a nontrivial task and previous studies have come to contradicting conclusions. One key potential problem is that changes in the historical observation network might introduce considerable errors. Here we estimate the likely magnitude of these errors for a subset of the available observations in the Southern Ocean. We test three common data analysis methods south of Australia and focus on the decadal-scale trends between the 1970's and the 1990's. Specifically, we estimate errors due to sparsely sampled observations using a known signal (the time invariant, temporally averaged, World Ocean Atlas 2001) as a negative control. The crossover analysis and the objective analysis methods are for less prone to spatial sampling location biases than the area averaging method. Subject to numerous caveats, we find that errors due to sparse sampling for the area averaging method are on the order of several micro-moles $kg^{-1}$. for the crossover and the objective analysis method, these errors are much smaller. For the analyzed example, the biases due to changes in the spatial design of the historical observation network are relatively small compared to the tends predicted by many model simulations. This raises the possibility to use historic oxygen trends to constrain model simulations, even in sparsely sampled ocean basins.

• Journal of Microbiology and Biotechnology
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• 제30권3호
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• pp.469-475
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• 2020

During meiosis I, programmed DNA double-strand breaks (DSBs) occur to promote chromosome pairing and recombination between homologs. In Saccharomyces cerevisiae, Mec1 and Tel1, the orthologs of human ATR and ATM, respectively, regulate events upstream of the cell cycle checkpoint to initiate DNA repair. Tel1^ATM and Mec1^ATR are required for phosphorylating various meiotic proteins during recombination. This study aimed to investigate the role of Tel1^ATM and Mec1^ATR in meiotic prophase via physical analysis of recombination. Tel1^ATM cooperated with Mec1^ATR to mediate DSB-to-single end invasion transition, but negatively regulated DSB formation. Furthermore, Mec1^ATR was required for the formation of interhomolog joint molecules from early prophase, thus establishing a recombination partner choice. Moreover, Mec1^ATR specifically promoted crossover-fated DSB repair. Together, these results suggest that Tel1^ATM and Mec1^ATR function redundantly or independently in all post-DSB stages.

• Steel and Composite Structures
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• 제24권1호
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• pp.113-128
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• 2017

This paper highlights a study undertaken on the free vibration of a precast steel-concrete composite slab panel for track support. The steel-concrete composite slab track is an evolvement from the slab track, a form of ballastless track which is becoming increasingly attractive to asset owners as they seek to reduce lifecycle costs and deal with increasing rail traffic speeds. The slender nature of the slab panel due to its reduced depth of construction makes it susceptible to vibration problems. The aim of the study is driven by the need to address the limited research available to date on the dynamic behaviour of steel-concrete composite slab panels for track support. Free vibration analysis of the track slab has been carried out using ABAQUS. Both eigenfrequencies and eigenmodes have been extracted using the Lanczos method. The fundamental natural frequencies of the slab panel have been identified together with corresponding mode shapes. To investigate the sensitivity of the natural frequencies and mode shapes, parametric studies have been established, considering concrete strength and mass and steel's modulus of elasticity. This study is the world first to observe crossover phenomena that result in the inversion of the natural orders without interaction. It also reveals that replacement of the steel with aluminium or carbon fibre sheeting can only marginally reduce the natural frequencies of the slab panel.

• Steel and Composite Structures
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• 제25권4호
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• pp.427-442
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• 2017

This paper presents unprecedented damped oscillation behaviours of a precast steel-concrete composite slab panel for track support. The steel-concrete composite slab track is an innovative slab track, a form of ballastless track which is becoming increasingly attractive to asset owners as they seek to reduce lifecycle costs and deal with increasing rail traffic speeds. The slender nature of the slab panel due to its reduced depth of construction makes it susceptible to vibration problems. The aim of the study is driven by the need to address the limited research available to date on the dynamic behaviour of steel-concrete composite slab panels for track support. Free vibration analysis of the track slab has been carried out using ABAQUS. Both undamped and damped eigenfrequencies and eigenmodes have been extracted using the Lancsoz method. The fundamental natural frequencies of the slab panel have been identified together with corresponding mode shapes. To investigate the sensitivity of the natural frequencies and mode shapes, parametric studies have been established, considering concrete strength and mass and steel's modulus of elasticity. This study is the world first to observe crossover phenomena that result in the inversion of the natural orders without interaction. It also reveals that replacement of the steel with aluminium or carbon fibre sheeting can only marginally reduce the natural frequencies of the slab panel.