• 한국방사선학회논문지
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• 제7권1호
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• pp.25-30
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• 2013

본 논문은 1998년부터 2011년까지 강릉 지역의 지방 방사능 측정소에서 측정된 공간 감마선량률의 통계 적인 성질을 조사하였다. Autocorrelation Function Analysis(ACF), Rescaled Range Analysis(R/S Analysis), Detrended Fluctuation Analysis(DFA)의 방법들이 사용되었으며, 이 중 DFA는 non-stationary한 시계열의 장거리 상관성을 보여주는 좋은 방법으로 알려져 있다. 우리는 이 연구를 통해 다음의 사실을 알았다. 첫 번째, 공간 감마선량률은 두 가지 다른 경향을 갖는 크로스 오버가 나타난다. 이것은 연중 공간 감마선량률은 강한 장기 기억 특성이 나타나는데 비해 연간으로 넘어가면 상관성이 사라지는 것을 의미한다. 두 번째, 각 분석 방법들의 지수들이 있는데 이 지수들 사이의 관계식이 맞음을 확인 하였다.

• 한국콘텐츠학회논문지
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• 제12권10호
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• pp.116-127
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• 2012

최근 국내 해양레저 인구의 급속한 증가에 따라 해양 레저산업이 발달할 수 있는 좋은 기회를 맞이하고 있다. 이러한 배경을 바탕으로 해양레저 용품 중 가장 범용성 있는 제품인 공기주입식 튜브데 대한 아이디어 상품개발은 국내 해양레저기업의 매출확대와 신시장 개척을 도울 수 있을 것이다. 연구방법으로는 크게 4단계로 나누어, 기초 선행연구조사(Investigation) - 조사결과의 분석과 종합 (Analysis & Synthesis) - 제품 디자인 개발(Development) - 제품 디자인개발안 평가(Evaluation)로 진행하였다. 본 연구에서는 공기주입식 튜브에 패브릭 커버를 씌워 쿠션 또는 아동용 놀이 가구로써 365일 가정에서 이용할 수 있는놀이형 튜브쿠션 디자인을 제안 하였다. 커버로는 촉감이 좋은 감성적 소재의 네오프렌(Neoprene)과 에어메시(Air-mesh) 패브릭을 사용하여 지퍼를 달아 씌우고 벗기기 쉽도록 하였다. 그리고 튜브끼리 끼워 조립하고, 스냅단추가 부착된 스트랩으로 연결하여 의자, 테이블, 터널, 기차 등 다양하게 응용할 수 있어 창의적인 놀이 활동이 가능도록 배려된 디자인이다. 본 연구는 해양레저 상품의 장기적 안목의 관점에서 차별화된 아이디어 상품으로 해양레저 용품 뿐 만 아니라 가정 및 어린이 놀이시설 등 크로스오버(Crossover)된 새로운 블루오션(Blue Ocean)시장을 창출 할 것으로 기대한다.

• Journal of Pharmaceutical Investigation
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• 제36권1호
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• pp.59-65
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• 2006

The purpose of this study was to evaluate the bioequivalence of two amlodipine maleate tablets, SKAD tablet (SK Pharma. Co., Ltd., Seoul, Korea, reference drug) and A-PINE tablet (Daewon Pharm. Co., Ltd., Seoul, Korea, test drug), according to the guidelines of Korea Food and Drug Administration (KFDA). Twenty-four healthy male volunteers, $22.79\;{\pm}\;1.86$ years in age and $70.08\;{\pm}\;8.68$ kg in body weight, were divided into two groups and a randomized $2\;{\time}\;2$ crossover study was employed. After a tablet containing 6.42 mg of amlodipine maleate was orally administrated, blood was taken at predetermined time intervals over a period of 144 hr and concentrations of amlodipine in plasma were monitored using LC-MS/MS. Pharmacokinetic parameters such as $AUC_t$ (the area under the plasma concentration-time curve from time zero to 144 hr), $C_{max}$ (maximum plasma drug concentration) and $T_{max}$ (time to reach $C_{max}$) were calculated and analysis of variance (ANOVA) test was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$ and $C_{max}$, and untransformed $T_{max}$. No significant sequence effect was found for all of the bioavailability parameters indicating that the crossover design was properly performed. The 90% confidence intervals of the $AUC_t$ ratio and the $C_{max}$ ratio for A-PINE/SKAD were $log\;0.9429{\sim}log \;1.1476$ and $log\;0.9l46{\sim}log\;1.1488$, respectively. Since these values were within the acceptable bioequivalence intervals of $log\;0.80{\sim}log\;1.25$, recommended by KFDA, it was concluded that A-PINE tablet was bioequivalent to SKAD tablet, in terms of both rate and extent of absorption.

• 대한기계학회논문집B
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• 제27권10호
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• pp.1393-1400
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• 2003

Ignition of hydrogen and oxygen in the "third limit" is theoretically investigated in the stagnation point flow with activation energy asymptotics. With the steady-state approximations of H, OH, O and HO$_2$, a two-step reduced kinetic mechanism is derived for the regime lower than the crossover temperature T$_{c}$ at which the rates of production and consumption of all radicals are equal. Appropriate scaling of Damkohler number successfully provides the explicit relationship between pressure, temperature and strain rate at ignition. It is shown that, compared with those for the counterflow, ignition temperatures for the stagnation point flow are considerably increased with increasing the system pressure. This is because ignition in the "third limit" is characterized by the production of reduction of $H_2O$$_2$, which is reduced by wall effect. Strain rate substantially affects ignition temperature because key reaction rates of $H_2O$$_2$ are comparably with its transport rate, while the mixture temperature and the hydrogen composition do not significantly affect ignition temperature.e.

• 성인간호학회지
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• 제27권1호
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• pp.106-116
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• 2015

Purpose: The purpose of this review was to assess the quality and to evaluate the effectiveness of music interventions in reducing agitation in older adults with dementia. Methods: Randomized controlled studies and randomized crossover studies were identified by searching MEDLINE, EMBASE, CINAHL, PsycINFO, AGELINE, Cochrane Central Register of Controlled Trials, Korea Med, Kmbase, RISS, National Assembly Digital Library, KISS, and RICH. Two reviewers independently retrieved articles, extracted data, and assessed the quality of studies. Results: In total, 10 studies were selected from 1095 unique citations. All included studies were conducted in long term care settings. Overall, risk of bias for included studies was low to moderate. The weighted average effect size across studies was -0.39 (95%CI [-0.69, -0.10], p=.009, $I^2=63%$). Music therapy was effective to reduce agitation of the older adults with dementia. Conclusion: Music intervention can be an effective non-pharmacological intervention for the reduction of agitation in dementia. Future studies need to use rigorous research method and to provide description of research methods in greater detail. In addition, future studies are required to explore the effects of music therapy according to severity of agitation and dementia.

• 한국물환경학회지
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• 제23권5호
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• pp.697-704
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• 2007

This study proposes an integrated technique of Genetic Algorishim (GA) and Geographic Information System (GIS) for designing the water quality monitoring networks. To develop solution scheme of the integrated system, fitness functions are defined by the linear combination of five criteria which stand for the operation objectives of water quality monitoring stations. The criteria include representativeness of a river system, compliance with water quality standards, supervision of water use, surveillance of pollution sources and examination of water quality changes. The fitness level is obtained through calculations of the fitness functions and input data from GIS. To find the most appropriate parameters for the problems, the sensitivity analysis is performed for four parameters such as number of generations, population sizes, probability of crossover, and probability of mutation. Using the parameters resulted from the sensitivity analysis, the developed system proposed 110 water quality monitoring stations in the Nakdong River. This study demonstrates that the integrated technique of GA and GIS can be utilized as a decision supporting tool in optimized design for a water quality monitoring network.

• 한국융합학회논문지
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• 제9권6호
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• pp.271-277
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• 2018

이 연구의 목적은 우리나라 지역거주 노인의 낙상 리스크를 평가하는 문항을 선정하고 유효성을 검토하는데 있다. 낙상위험 평가는 선행연구를 참고로 '낙상잠재성', '신체기능', '질병과 신체증상', '환경', '행동과 성격'의 5가지 요인으로 구분하였으며 내용타당성 검증, 교차분석 및 요인분석 결과에 따라 총 44개 문항으로 구성하였다. 한국형 낙상위험 평가척도는 심각한 사회문제로 인식되고 있는 노인의 낙상문제를 개선하고 개인의 낙상예방에 중요한 정보를 제공하는데 유용한 도구로 사용될 수 있을 것이다.

• 환경영향평가
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• 제22권6호
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• pp.713-724
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• 2013

In terms of waste load allocation, inequality of waste load discharge must be considered as well as economic aspects such as minimization of waste load abatement. The inequality of waste load discharge between areas was calculated with Gini coefficient and was included as one of the objective functions of the multi-objective waste load allocation. In the past, multi-objective functions were usually weighted and then transformed into a single objective optimization problem. Recently, however, due to the difficulties of applying weighting factors, multi-objective genetic algorithms (GA) that require only one execution for optimization is being developed. This study analyzes multi-objective waste load allocation using NSGA-II-aJG that applies Pareto-dominance theory and it's adaptation of jumping gene. A sensitivity analysis was conducted for the parameters that have significant influence on the solution of multi-objective GA such as population size, crossover probability, mutation probability, length of chromosome, jumping gene probability. Among the five aforementioned parameters, mutation probability turned out to be the most sensitive parameter towards the objective function of minimization of waste load abatement. Spacing and maximum spread are indexes that show the distribution and range of optimum solution, and these two values were the optimum or near optimal values for the selected parameter values to minimize waste load abatement.

• Nuclear Engineering and Technology
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• 제50권6호
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• pp.829-841
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• 2018

An experiment was conducted for the OECD/NEA ROSA-2 Project using the large-scale test facility (LSTF), which simulated a 17% hot leg intermediate-break loss-of-coolant accident in a pressurized water reactor (PWR). In the LSTF test, core uncovery started simultaneously with liquid level drop in crossover leg downflow-side before loop seal clearing, and water remaining occurred on the upper core plate in the upper plenum. Results of the uncertainty analysis with RELAP5/MOD3.3 code clarified the influences of the combination of multiple uncertain parameters on peak cladding temperature within the defined uncertain ranges. For studying the scaling problems to extrapolate thermal-hydraulic phenomena observed in scaled-down facilities, an experiment was performed for the OECD/NEA PKL-3 Project with the Primarkreislaufe Versuchsanlage (PKL), as a counterpart to a previous LSTF test. The LSTF test simulated a PWR 1% hot leg small-break loss-of-coolant accident with steam generator secondary-side depressurization as an accident management measure and nitrogen gas inflow. Some discrepancies appeared between the LSTF and PKL test results for the primary pressure, the core collapsed liquid level, and the cladding surface temperature probably due to effects of differences between the LSTF and the PKL in configuration, geometry, and volumetric size.

• 농촌지도와개발
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• 제28권2호
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• pp.85-98
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• 2021

This study aims to examine consumer types based on pet food selection attributes and to analyze the differences in consumer characteristics by those types. In this study, the researcher uses k-means cluster analysis and crossover analysis to determine market segmention, and then analyzes the resultant characteristics by categorizing consumers. A total of 202 cases are used for this study. First, the selection attributes are classified into the six factors of credibility, quality, design, convenience, information, and price. Second, the clusters are categorized into the four clusters, which are designated pet food lower-involvement type, pet food information- and price-seeking type, pet food convenience-seeking type, and pet food higher-involvement type. Third, these four groups exhibit statistically significant differences in terms of occupational variables, number of pets, and purchase frequency. The results of this study may provide helpful information in establishing customized, market-based marketing strategies based on the characteristics of pet food consumers.