• 제목/요약/키워드: cross-over studies

검색결과 359건 처리시간 0.025초

Seroprevalence of Toxocariasis among Healthy People with Eosinophilia

  • Kim, Yong-Hun;Huh, Sun;Chung, Young-Bae
    • Parasites, Hosts and Diseases
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    • 제46권1호
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    • pp.29-32
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    • 2008
  • The aim of this study is to determine the Toxocara seropositive rate among healthy people with eosinophilia. A total of 97 people residing in Seoul who were healthy and whose blood eosinophilia was over 10%, as shown by regular health check-ups in 2004, were subjected to this study. Their sera were tested by immunoblotting and ELISA with the antigen of larval Toxocara canis excretory-secretory (ES) protein. Sixty-five sera were band-positive (67.0%). The seropositve control sera were positive to band sizes of 66 kDa, 56 kDa, 32 kDa, and 13 kDa. In ELISA, 63 sera (65.0%) were positive to T. canis ES protein. There was no significant correlation between the IgG ELISA titer and the level of eosinophilia (r = 0.156, P = 0.156). As there were insufficient data to determine whether there were cross-reactions with other helminthic infections, or whether atopy occurred, further studies are required to verify the cause of the seropositive reactions against T. canis ES antigen. Toxocariasis seropositivity is suggested to be the major cause of eosinophilia, since the Toxocara seroprevalence among Korean rural adults was shown to be approximately 5%.

Breast Cancer in Ardabil Province in the North-West of Iran: an Epidemiological Study

  • Fouladi, Nasrin;Pourfarzi, Farhad;Amani, Firooz;Ali-Mohammadi, Hossein;Lotfi, Ilshan;Mazaheri, Effat
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권4호
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    • pp.1543-1545
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    • 2012
  • Breast cancer accounts for about 26% of all newly diagnosed cancers in women aged 20 to 59 years. As part of a basic program for cancer control, the present cross sectional descriptive study was conducted with the objective of determining the epidemiology of breast cancer in Ardabil province during 2003-2010. Necessary information on 469 recorded cases of breast cancer in the registry were collected by check list from patient's files and then analyzed by statistical methods with SPSS.16 software. Some 455 of the patients (97%) were female, 329 (70.1%) residing in Ardabil. The mean age was $46.8{\pm}13.6$ and most were in the age group of 40 - 60. The most prevalent pathologic form was infiltrative ductal carcinoma with 316 cases (67.4%), the largest proportion being grade II (30.6%), but very many belonged to grades III and IV (40.5%). Breast cancer in Ardabil province appeared to slightly increase over the period studied. The results were similar to other places in Asia. With regard to this, more widespread studies are required to determine factors influencing the prevalence at low age and also how to promote early detection.

장지간 교량을 위한 PSC-I형 거더의 단면 설계변수 연구 (A Study on the Design Parameters of the PSC I-Type Girders for Long Span Bridges)

  • 심종성;오홍섭;김민수
    • 콘크리트학회논문집
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    • 제12권6호
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    • pp.13-22
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    • 2000
  • In order to resolve the problem of increasing traffic entailed by the economic development, road system is reorganization and new highways are built, and long span bridges over 40m are being constructed in environmental and aesthetic considerations. Most long span bridges that are currently being constructed are in general steel box girder and preflex girder bridges; however these types of breiges are less efficiency than PSC I-type girder bridges in terms of construction cost and maintenance. Therefore, in these study, structural efficiency of PSC I-type girders based on section parameters, concrete compressive strength and other design parameter is observed to develope new PSC I-type girder for long span bridges. As a results of analysis, most important design parameters that control the stress of the girder are found to be the top flange width and the height of girder. In this light, the relationship between the two variables is determined and cross-section details of the girder that most appropriates for the long span bridges are proposed. The use of high strength concrete appears to increase the general design span however the increase rate of the span from increasing concrete ultimate strength appears to be reduced depending on the span. Also, the optimal girder spacing is determined through the parameter studies of design span using the proposed girder.

METHODS TO IMPROVE UTILIZATION OF RICE STRAW II. EFFECTS OF DIFFERENT LEVELS OF FEEDING ON INTAKE AND DIGESTIBILITY OF UNTREATED AND UREA AMMONIA TREATED RICE STRAW

  • Badurdeen, A.L.;Ibrahim, M.N.M.;Schiere, J.B.
    • Asian-Australasian Journal of Animal Sciences
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    • 제7권2호
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    • pp.165-169
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    • 1994
  • Forty cross bred ($168\;{\pm}\;28\;kg$) bull calves were offered either untreated (US) or urea ammonia treated (TS) rice straw at five levels of feeding, namely; 60, 80, 100, 120 140% of ad libitum. Ad libitum level for each animal was estimated over a period of one month, which was followed by a preliminary period of 21 days and a collection period of 15 days. The maximum organic matter intake (OMI-kg/100 kg BW) were 2.08 and 3.35 for US and TS, respectively and urea treatment increased the maximum OMI by 61% than for US. In order to reach maximum intake the amount feed refusal should be 25% for US, but with TS maximum intake was not reached even when the amount of feed refused was 39% of that consumed. The OMD of US significantly decreased with increase in OMI, whereas with TS the decrease was not significant. The inability of animals to select between stems and leaves particularly in TS might be one of the reasons for its constant digestibility. Considering the substantial increases in intake and the negative effect on digestibility of US, further trials are warranted, as well as studies to determine the practical implications.

METHODS TO IMPROVE UTILIZATION OF RICE STRAW I. EFFECTS OF MOISTENING, SODIUM CHLORIDE AND CHOPPING ON INTAKE AND DIGESTIBILITY

  • Badurdeen, A.L.;Ibrahim, M.N.M.;Schiere, J.B.
    • Asian-Australasian Journal of Animal Sciences
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    • 제7권2호
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    • pp.159-164
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    • 1994
  • Two studies were conducted using 40 cross-bred bulls to study the effect of chopping, moistening with water or common salt solution on the nutritive value of rice straw (variety BG-400). Moistening with water did not significantly effect digestibility or intake of rice straw. As compared to straw fed in the long form, chopping did not significantly influence intake (2.33 vs 1.97kg $100kgBW^{-1}day^{-1}$, respectively), but significantly (p<0.05) decreased the digestibility (41.6 vs 37.4%) and intake of digestible dry matter (0.99 vs 0.74kg $100kgBW^{-1}day^{-1}$). Rice straw moistened with 2 or 4% common sea salt solution and directly fed to animals (Exp. 1) did not significantly effect its digestibility (43.9 and 43.1%, respectively) or intake (2.66 or 2.59kg $100kgBW^{-1}day^{-1}$, respectively), but over night storing of 2% salt solution sprayed straw (Exp. 2) significantly reduced its digestibility (33.6%). The latter is difficult to explain because the sodium concentration (mg/g straw dry matter) was lower than 4% salt solution treatment used in experiment 1 (3.30 vs 5.22). It is concluded that chopping, moistening with water or NaCl salt solution did not significantly improve the nutritive value of rice straw.

설사증 이환견(罹患犬)으로 부터 분리한 canine parvovirus의 성상에 관한 연구 (Biological and physicochemical properties of canine parvovirus isolated from the dogs with diarrhea)

  • 최해연;전무형;박성국
    • 대한수의학회지
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    • 제31권3호
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    • pp.295-302
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    • 1991
  • From 1988 to 1989, 8 strains of canine parvovirus-2(CPV-2) were isolated from the fecal specimens from the dogs that were clinically diagnosed as canine parvoviral enteritis in the veterinary hospitals located in the regions of Taejeon and Chungbuk province. The biological and physicochemical properties for the isolates were studied. Among 62 fecal samples collected from the dogs with enteric diseases, 24(38.7%) showed the haemagglutinating activity to porcine erythrocyte ranging from 16 to 16,384 of HA titers. In cytopathological studies with CRFK cells, intranuclear inclusion bodies were observed in all of eight specimens with the high HA titer over 1,000, of which three specimens showed cytoplasmic inclusions concurrently with the intranuclear inclusion bodies. It was found that the isolates revealed the highest haemagglutinating activity with porcine erythrocytes and the relatively lower haemagglutination titers with the erythrocytes from cat and rabbit. None of erythrocytes from the other animals reacted with the isolates. By the cross-haemagglutination inhibition test for the isolates with the reference viruses and sera, the isolates were evidently identified as the strains of CPV-2. In physicochemical property test, the isolates were stable in lipid solvent, pH and heat treatment at $56^{\circ}C$ for 30 min, and showed the virus particle size less than 25 nm, containing a DNA genome.

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백혈병환자의 요추천자 후 침상안정시간에 따른 두통과 요통의 차이 (Difference of Pain Depending on the Bed Rest Period after Lumbar Puncture in Patients with Leukemia)

  • 정영남;이향련;박영미
    • 동서간호학연구지
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    • 제14권1호
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    • pp.36-43
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    • 2008
  • Purpose: This study was conducted for an evidence-based nursing intervention on bed rest period after puncture, by confirming whether there was a difference in scores of headache and back pain between the 1-hour bed rest group and the 6-hour bed rest group following lumbar puncture in patients with leukemia. Method: The subjects were 45 inpatients of the department of hematology at a general hospital in Seoul, from January 1 to March 31, 2005. There were 21 patients in the 1-hour bed rest group and 24 patients in the 6-hour bed rest group. A graphic rating scale was used to measure headaches and back pains. Collected data were analyzed with SPSS 12.0. Non- parametric statistics were used to analyze the data. Results: There was no significant difference between the 1-hour bed rest group and the 6-hour bed rest group in the headache level and back pain level. Conclusion: Therefore, it is considered that a long period of bed rest over 6 hours after lumbar puncture is not a necessary nursing intervention, and repeated studies are required to confirm the result.

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IT컨설팅 서비스 품질 측정에 대한 타당성 검증에 관한 연구 (The Validity of IT Consulting SERVQUAL Measurement Tool)

  • 서현석
    • Journal of Information Technology Applications and Management
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    • 제12권3호
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    • pp.111-128
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    • 2005
  • This paper examines the validity of the newly developed IT consulting SERVQUAL measurement tool. In an attempt to measure Ire IS customers' expectations and perceived quality of the services they received, the researchers developed a diagnostic tool of SERVQUAL based on the solid theoretical background, which can specifically be applied to the IT consulting service sector. This on-going research so far, has been applied to six (6) different organizations that have received IT consulting services over the past years. From the preliminary data collected, the correlation and the factor analyses were conducted to understand the underlying concept and refinement of the measurement tool. Although the correlation analysis showed a little tendency of collinearity among some of the variables, all showed sound relationship of the proposed hypotheses. The exploratory factor analytic approach was chosen because it does not set any priori constraints on the estimation of components or the number of components to be extracted. The number of different factor solutions was extracted and tested to see which solution represents better grouping of the variables. The Crombach's Alpha was computed on different combinations of the factor solutions to ensure validity. The results show 8-dimensional IT consulting SERVQUAL measures which they are, assurance, knowledge & skill, customer relationship, support, empathy, process management, expertise, and education, seem more appropriate than the originally proposed 6 dimensions. The study approach was non-experimental cross-sectional research design. The longitudinal design of follow-up studies to periodically revise and refine current measure is strongly recommended for fine tuning of the tool.

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청감실험을 통한 철도소음의 자율신경 및 심혈관계통 영향도 연구 (The Research of Railway Noise through Auditory Experiments Focused on the Autonomic Nervous System and Cardiovascular System)

  • 이재관;윤은선;장채미;제세영;장서일
    • 한국소음진동공학회논문집
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    • 제26권6_spc호
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    • pp.674-679
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    • 2016
  • According to the conventional studies on the noise and cardiovascular effect, railway noise is better associated with hypertension and adverse cardiovascular events than road traffic noise. But the underlying mechanisms remain unclear. We investigated the hypothesis that exposure to acute railway noise would the unfavorable effect of cardiovascular and autonomic system in healthy young subjects. Using a randomized, sham-controlled cross-over design, ten subjects were assigned to receive either an exposure to high speed train noise (84 dB) for 30 minutes or a control condition (non noise), separated by two days. Blood pressure, heart rate, augmentation index and heart rate variability as indices of cardiovascular and autonomic system function were measured at baseline, during, and recovery from two trials. The results show that exposure to acute railway noise significantly increased diastolic blood pressure and augmentation index, which may cause of adverse cardiovascular effects.

Effects of Body-Adhesive Backpack Condition on Craniovertebral Angle, Sagittal Shoulder Angle and Muscle Fatigue

  • Son, Jinkyu;Kim, Ho;Shin, Wonseob
    • 국제물리치료학회지
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    • 제11권4호
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    • pp.2203-2211
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    • 2020
  • Background: Backpacks are one of the most widely used accessories in modern society. However, previous studies have shown that carrying a backpack can cause various musculoskeletal problems. Objectives: To investigate the effects of a body-adhesive backpack on craniovertebral angle, sagittal shoulder angle and the muscle fatigue in the upper extremity. Design: Randomized cross-over design. Methods: For this study, 36 healthy university students participated in this study. The experiment was conducted three times using common backpack, and body-adhesive backpack condition. The angles of the cervical spine and shoulder joints of the subjects were calculated without the backpack. Electrodes were placed at upper trapezius, lower trapezius, rectus abdominis and erector spinae to check for muscle fatigue. Subjects carried a backpack and walked on a treadmill for 15 minutes at 4 km/h. The muscle fatigue signal was also measured while walking. After walking, the craniovertebral and sagittal shoulder angles were measured again while subjects carried backpack. Results: As a result of this study, body-adhesive backpack condition showed significant decrease and significant increase in craniovertebral angle and sagittal shoulder angle than common backpack (P<.05). Body-adhesive backpack condition showed significant decrease in upper trapezius, lower trapezius, erector spinae, and rectus abdominis when compared to a common backpack (P<.05). Conclusion: This study suggests that a body-adhesive backpack is more beneficial in correcting body posture than a common backpack.