• 제목/요약/키워드: cross-over studies

검색결과 355건 처리시간 0.028초

Heavy ion effects on mode conversion between electron and proton whistlers : A simulation study

  • 김은화;이동훈
    • 한국우주과학회:학술대회논문집(한국우주과학회보)
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    • 한국우주과학회 2003년도 한국우주과학회보 제12권2호
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    • pp.37-37
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    • 2003
  • Electron whistlers frequently excite proton whistlers. The proton whistlers appear on the dynamic spectrum as rising tones, which start after the reception of a short electron whistler, asymptotically approaching the local proton gyro-frequency. The proton whistlers are dispersed forms of lightning impulses and their dispersion can be explained by the effects of heavy ions such as H+ and He+ on the propagation of an electromagnetic wave in the ionosphere. In the ionosphere, a right-handed circularly-polarized electron whistler becomes coupled to a left-handed circularly-polarized proton whistler when the frequency becomes close to a cross-over frequency. By adopting the multi-fluid numerical wave model, we examine how the mode coupling varies as the ion composition changes along altitude in the mid-latitude ionosphere. The time histories and dynamic spectra of electric fields are presented. In addition, we compare our results with the previous theoretical and observational studies.

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튜닝 가능한 자원선택 방법론 (Methodologies to Selecting Tunable Resources)

  • 김혜숙;오정석
    • Journal of Information Technology Applications and Management
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    • 제15권1호
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    • pp.271-282
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    • 2008
  • Database administrators are demanded to acquire much knowledges and take great efforts for keeping consistent performance in system. Various principles, methods, and tools have been proposed in many studies and commercial products in order to alleviate such burdens on database administrators, and it has resulted to the automation of DBMS which reduces the intervention of database administrator. This paper suggests a resource selection method that estimates the status of the database system based on the workload characteristics and that recommends tuneable resources. Our method tries to simplify selection information on DBMS status using data-mining techniques, enhance the accuracy of the selection model, and recommend tuneable resource. For evaluating the performance of our method, instances are collected in TPC-C and TPC-W workloads, and accuracy are calculated using 10 cross validation method, comparisons are made between our scheme and the method which uses only the classification procedure without any simplification of informations. It is shown that our method has over 90% accuracy and can perform tuneable resource selection.

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Three-Dimensional Quantitative Structure Activity Relationship Studies on the Flavone Cytotoxicity and Binding to Tubulin

  • Kim, Ja-Hong;Sohn, Sung-Ho;Hong, Sun-Wan
    • Journal of Photoscience
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    • 제8권3_4호
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    • pp.119-121
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    • 2001
  • Three-Dimensional Quantitative Structure-Activity Relationship(QSAR) has been investigated over 67 flavonoids to correlate and predict GI$\sub$50/ values. The partial least-squares(PLS) model was performed to calculate the activity of each derivatives, and this was compared with the actual value. The results of the cross-validated(${\gamma}$$^2$=0.997) values show that cytotoxic activities play an important role which is in good agreement with the observed GI$\sub$50/ values.

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LEVEL OF TESTOSTERONE IN BLOOD PLASMA OF SELECTED RAMS

  • Abdul Wahid, S.;Yunus, J.M.
    • Asian-Australasian Journal of Animal Sciences
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    • 제8권6호
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    • pp.583-585
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    • 1995
  • Following importation of temperate Australian breeds of sheep into Malaysia, it was demonstrated that there was variability in libido and semen productivity. Consequently, a study was conducted to determine the concentration of testosterone and relate it with libido and semen production. A total of 10 rams each of Dorset Horn, Cross of Merino with Border Leicester, Siamese Long Tail, Suffolk and local Malin were used to study the composition of testosterone in the blood plasma of these breeds. The study showed that there was significant difference between the testosterone level of different breeds in Spring and Summer but not in Autumn and Winter. The difference was pronounced in August and January. A significant difference (p > 0.05) was recorded in the testosterone levels of the different breeds during the day where Malin had better libido compared to the other breeds. There was no significant difference between the testosterone levels of the different breeds at night. The testosterone level of Suffolk, however, was elevated throughout the night (2.00 ng/ml and over) which resulted in better libido at night compared to the other breeds.

강건 실험계획법을 이용한 열화자료의 분석 (Analysis of Degradation Data Using Robust Experimental Design)

  • 서순근;하천수
    • 품질경영학회지
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    • 제32권1호
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    • pp.113-129
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    • 2004
  • The reliability of the product can be improved by making the product less sensitive to noises. Especially, it Is important to make products robust against various noise factors encountered in production and field environments. In this paper, the phenomenon of degradation assumes a simple random coefficient degradation model to present analysis procedures of degradation data for robust experimental design. To alleviate weak points of previous studies, such as Taguchi's, Wasserman's, and pseudo failure time methods, novel techniques for analysis of degradation data using the cross array that regards amount of degradation as a dynamic characteristic for time are proposed. Analysis approach for degradation data using robust experimental design are classified by assumptions on parametric or nonparametric degradation rate(or slope). Also, a simulation study demonstrates the superiority of proposed methods over some previous works.

시판 설프이속사졸정의 용출거동 및 상대 생체이용율 (Dissolution Behavior and Relative Bioavailability of Commercially Available Sulfisoxazole Tablets in Humans)

  • 고익배;이용복
    • Journal of Pharmaceutical Investigation
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    • 제17권3호
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    • pp.127-133
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    • 1987
  • Dissolution characteristics and urinary excreted amount of commercially available three brands of sulfisoxazole tablets were investigated in order to elucidate the in vitro-in vivo correlations and relative bioavailability in humans. All the tablets tested met the K.P. IV and the USP XXI specifications for tablet weight variation, content uniformity, disintegration and dissolution. The disintegration and dissolution rate constants of sulfisoxazole tablets in pH 2.0 HCl-KCl buffer were reduced more significantly (p<0.05) than those in diluted HCl $(1{\rightarrow}12.5)$ and pH 6.5 phosphate buffer. It seemed to be attributed to the pH dependent solubility of sulfisoxazole. We could see that the relative bioavailability of brand B to sulfisoxazole powder was about 90% and that its value was higher than those of other two brands from the urinary excretion data obtained from eight healthy male volunteers by means of Latin square cross over design. No useful correlation was observed between the in vitro and in vivo studies in this experiment.

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액체중의 원형 실린더 주위에서의 강제대류 층류 열전달에 관한 수치해석적 연구 (A Numerical Study on the Laminar convective Heat Transfer around a Circular Cylinder in a Uniform Cross Flow of Liquid)

  • 강신형;홍기혁
    • 설비공학논문집
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    • 제8권1호
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    • pp.26-36
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    • 1996
  • Many researches were carried out to estimate heat transfer rate on a circular cylinder in a uniform flow. Various empirical correlations were suggested in the past through experimental studies, however there are considerable discrepancies in the estimated values of heat transfer coefficient. The effect of fluid physical properties on the forced convective heat transfer between a circular cylinder and the external flow was numerically investigated in the present study, The flow and temperature fields were solved using a Finite Volume Method over a wider range of Prandtl number(0.7-40,000) than existing correlations. The cold as well as the hot cylinders in the uniform liquid flow of constant temperature were investigated. A unified correlation was obtainde for both cases.

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Theoretical Studies on Phenyl Group Rearrangement of Protonated Ketones

  • 김창곤;이진각;박형연;이익춘
    • Bulletin of the Korean Chemical Society
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    • 제18권6호
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    • pp.657-662
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    • 1997
  • Gas-phase phenyl group migration within the protonated ketones has been studied MO theoretically using the AM1 method. The initial state structure shows relatively strong resonance delocalization of positive charge into the nonmigrating (Y) ring, while the ring migration (Z-ring) is nearly complete in the transition state. These results are reflected in the large $p^+_Z$ (<0) and $p^+_$Y (>0) values and in the predominant contribution of resonance (r) over inductive (field, f) effect, r/f ranging from 1.3 ($p^+_r$) to 1.5 ($p^+_z$). The cross-interaction constant $p_{YZ}$ is vanishingly small ($p_{YZ}$=0.03) which is in contrast to the larger magnitudes for benzilic ($p_{YZ}$=-0.48) and azibenzil ($p_{YZ}$=-0.53) rearrangement processes. The relationship found between the extent of resonance contribution in the initial state and the magnitude of $p_{YZ}$ provides strong support for the proportionality between the magnitude of $p_{YZ}$ and the change in the intensity of interaction, ${\Delta}I^{\cdot}_{YZ}$, in the activation process.

혈중 C-Reactive Protein 농도와 급성기 뇌졸중에 대한 단면적 연구 (Cross-sectional Study of Plasma Concentration of C-Reactive Protein and Acute Stroke)

  • 김형도;여인영;전우현;박정미
    • 대한한방내과학회지
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    • 제25권1호
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    • pp.132-137
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    • 2004
  • Background : Recent studies have demonstrated relations between inflammation and stroke. The aim of this study was to investigate CRP level in independent risk factors of stroke patients. Method : Thirty-five ischemic stroke patients were included in this study from Febrary to September 2003. Plasma concentration of CRP was measured over 72 hours after stroke. We examined a average CRP level and associations between CRP and other variables. Result : This study didn't show high CRP level in stroke patients comparing with recent reported studies. Associations between CRP level and other variables didn't show any significant change. Conclusion: In this study, CRP level was not associated with acute stroke significantly.

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The Role of Milk Products in Metabolic Health and Weight Management

  • Zemel, Michael B.
    • Journal of Dairy Science and Biotechnology
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    • 제28권1호
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    • pp.17-28
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    • 2010
  • A substantial body of evidence has emerged over the last decade in support of the novel concept that dietary calcium and dairy foods play an important role in regulating energy metabolism and thereby promote healthy weight management and reduce obesity risk. This concept has been demonstrated in experimental animals studies, cross-sectional and prospective population studies and a number of randomized clinical trials. Notably, the effects of dairy foods in weight management are more consistent than the effects of supplemental calcium across clinical trials, and calcium per se is responsible for approximately 40-50% of the effects of dairy. The calcium component is only effective in individuals with chronically low calcium intake, as it serves to prevent the endocrine response to low calcium diets which otherwise favors adipocyte energy storage; calcium also serves to promote energy loss via formation of calcium soaps in the gastrointestinal tract and thereby reduce fat absorption. The calcium-independent anti-obesity bioactivity of dairy resides primarily in whey. The key components identified to date are leucine and bioactive peptides resulting from whey protein digestion. The high concentration of leucine in whey stimulates a repartitioning of dietary energy from adipose tissue to skeletal muscle where it provides the energy required for leucine-stimulated protein synthesis, resulting in increased loss of adipose tissue and preservation of skeletal muscle mass during weight loss. Finally, dairy rich diets suppress the oxidative and inflammatory responses to obesity and thereby attenuate the diabetes and cardiovascular disease risk associated with obesity.

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