• 한국동물위생학회지
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• 제17권2호
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• pp.95-113
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• 1994

To establish an effective diagnostic measure for detection of the antibodies against Actinobacillus pleuropneumoniae, the methods for tube agglutination test (TAT), plate agglutination test (PAT), micro-agglutination test(MAT) and agar-gel immunodiffusion test(ID) were improved and standarized, and the comparative studies were carried out. The results obtained through the experiments were summarized as follows. 1. The rabbit hyperimmune sera to reference serotypes 1 to 6 were cross-tested with TAT, PAT, MAT and ID. In the homologous systems, the range of antibody titers in TAT was 80 to 640, showing the cross-reaction in serotypes 3, 4, 5 and 6. The range of antibody titers in PAT was 4 to 64, showing the cross-reaction in serotypes 3, 4, 5 and 6. In ID, the range of antigen titers was 8 to 32, and cross-reaction was observed in serotype 5. 2. The optimal concentration of antigen in PAT and MAT were 100mg /ml and 1.25mg /ml respectively. The most sensitive reaction in MAT was observed in 52$^{\circ}C$ for 18hrs. 3. In ID, the most promising antigen and the buffer for agar-gel were EDTA-treated antigen and 0.05M tris buffer (pH 7.2), respectively. 4. By the tests for 200 swine sera, it was found that the frequency of positive reaction were 203 in TAT, 240 in PAT and 163 in ID. 5. When compared the titers of TAT with those of MAT for 200 swine sera, MAT showed the higher titer than TAT being increased by relative correlation. Int was found that the titer for positive readings were 20 in TAT and 40 in MAT. 6. when compared the results of ID with those of TAT for 200 swine sera, all sera with TAT titer under 10 were negative in ID. Of the sera with TAT titer 20 and 40, 55.1% nd 91.8% were positive in ID, respectively. All sera with TAT titer above 80 were positive in ID. In comparison of ID and MAT, all sera with MAT titer under 20 were negative in ID. Of the sera with MAT titer 40 and 80, 24.7% and 93.9% were positive in ID, respectively. All sera with MAT titer over 160 showed positive in ID. 7. In conclusion, the established MAT showed high sensitivity but low specificity, wherease ID revealed low sensitivity but high specificity.

• 한국농공학회논문집
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• 제66권2호
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• pp.1-12
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• 2024

In order to integrate two consolidation theories of Terzaghi's consolidation theory and Mesri's secondary compression theory and to identify a model suitable for analyzing stress-strain behavior over time, numerical analysis on consolidation tests were conducted using a modified cam-clay model and a soft soil creep model and the following conclusions were obtained. The results of numerical analysis applying the theory that a linear proportional relationship is established between the void ratio at logarithmic scale and the permeability coefficient at logarithmic scale is better agreement with the result of oedometer test than the results of applying constant hydraulic conductivity. The modified cam-clay model is a model that does not include secondary compression, but the slope of the normal consolidation line corresponding to the compression index of the standard consolidation test includes secondary compression, so the actual settlement curve over time is lower than the predicted value through numerical analysis. It always gets smaller. Other previous studies that applied Terzaghi's consolidation theory to consolidation test analysis showed the same results and were cross-confirmed. The soft soil creep model, which includes secondary compression in the theory, showed good agreement in all sections including secondary compression in the consolidation test results. It was judged appropriate to use a soft soil creep model when performing numerical analysis of soft clay ground.

• Journal of Preventive Medicine and Public Health
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• 제35권4호
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• pp.313-321
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• 2002

Objectives : To identify the risk factors of dementia among the elderly in a large city. Methods : A cross-sectional study was conducted in July 2001, with potential participants selected by stratified two stage cluster sampling of the elderly population of Keumgog dong, Busan. A total of 452 elderly people aged 65 years and over, underwent a two phase diagnostic procedure. Mini-mental State Examination-Korean (MMSE-K) and Samsung Dementia Questionnaire were used for the 1st stage, and the Clinical Dementia Rating Scale (CDR), the Bartel ADL, and IADL Index, the Korean Geriatric Depression Scale (KGDS), the Modified Hatchinski Ischemic Scale (MHIS), and other laboratory tests were used for the 2nd stage. Results : Of the 446 participants finally chosen, 45 were confirmed with dementia, and 363 as normal, with the rests not confirmed with dementia or as normal, were excluded from the analysis. According to the logistic regression analysis, the risk of dementia was significantly higher In: people aged 80 and above (OR=4.36, 95% CI=1.97-9.62), illiterate (OR=3.58, 95% CI=1.71-7.46), who had a history of strokes (OR=6.35, 95% CI=2.71-14.87), or who had 3 history of hyperlipidemia (OR=4.74, 95% CI=1.65-13.61), compared to their counterparts. Conclusions : These results suggest that efforts to prevent strokes and hyperlipidemia can significantly decrease the risk of dementia.

• 한국아동복지학
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• 제59호
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• pp.1-23
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• 2017

본 연구는 교차지연 모형을 사용하여 비혼 아버지(unmarried fathers)의 양육참여와 아동의 문제행동 간에 인과관계를 분석하였다. 분석을 위해 미국 취약가구 및 아동복지연구자료(Fragile Families and Child Wellbeing Study)를 사용하였으며, 아버지가 자녀와 동거하지 않는 비혼여성 한부모가구만 선별하여 총 3,409가구를 연구대상으로 설정하였다. 비혼 아버지의 양육참여는 아동방문빈도와 도구적 양육지원, 지지적 양육태도의 세 가지 하위변수로 측정하였으며, 아버지의 양육참여와 아동의 문제행동을 각각 아동의 3세와 5세, 9세 시점에서 반복측정한 변수를 사용하여 시간의 흐름에 따른 각 변수의 변화를 고려하였다. 연구결과, 비혼 아버지의 양육참여는 아동의 문제행동을 결정하는 유의미한 요인인 것으로 검증되었다. 전반적으로 아동연령 3-5세 시점에서 비혼 아버지의 적극적인 양육참여는 5-9세 시점에서의 아동문제행동을 감소시키는 것으로 분석되었다. 연구결과를 기초로 비혼 아버지의 지속적인 양육참여를 유도하기 위한 정책적 실천적 전략에 대해 논의하였으며, 동시에 보다 효과적으로 아버지의 역할과 책임을 이해하고 관련 기술을 습득할 수 있도록 자녀양육, 관계형성기술, 갈등해결 기술 등의 구체적인 서비스 제공 및 프로그램 개발과 지원방안을 제시하였다.

• Archives of Pharmacal Research
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• 제15권3호
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• pp.208-210
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• 1992

Comparative bioavailability of two tablet dosage forms of ofloxacin (either as Hoechst (India) or Ranbaxy preparation ) was investigated. In a randomized cross-over study, eitht healthy human volunteers received single 200 mg dose of film coated ofloxacin in fasting state. The concentration of ofloxacin in the collected saliva and serum samples were measured by high performance liquid chromatography. No significant difference in bioavailability of both preparations was judged from various serum and seliva pharmacokinetic parameters such as peak concentration, time to peak concentration and are under the curves. Intersubject variation was also found to be insignificant.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제43회 하계 정기 학술대회 초록집
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• pp.77-77
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• 2012

As interest has increased in the interaction between low-temperature plasmas and materials, the role of modeling and simulation of processing in plasma has become important in understanding the effects of charged particles and radicals in plasma applications. Thus in this presentation, we present the theoretical and experimental studies of electron impact cross section for plasma processing gas, such as plasma etching and deposition processes. Also, here the work conducted at the Data Center for Plasma Properties (DCPP) over last 7 years on the systematic synthesis and assessment of fundamental knowledge on low-energy electron interactions with plasma processing gases is briefly summarized and discussed.

• 대한간호학회지
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• 제33권5호
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• pp.544-552
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• 2003

Purpose: This study examined the health status among elderly in community. Method: This is a survey using cross-sectional design. The subjects were 531 elders who were 65 and over in Pusan, Korea. Data were collected by 17 trained interviewers from April 10 to August 26, 2000. Functional status for physical health status, depression, loneliness, self-esteem for psychological health status, and social support for social health status were measured. Result: About forty three percent of the subjects were found as the elderly who need support in physical status. About fifty six percent of the subjects were depressed. The mean score on the Loneliness scale was 40.4, which means relatively higher. For self-esteem, its score was lower than that of elderly who were examined in other studies. The subjects were living in the state of lower social support. The risk factors for vulnerable health status were being female, becoming older, lower income and education, and living alone. Conclusion: This finding indicates that the elderly subjects in Korean community were in poor health status in physical, psychological and social aspects.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 추계학술대회
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• pp.480-485
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• 2004

The applications of composite materials have increased over the past few decades in a variety of structures that require high ratio of stiffness and strength to weight ratios. Recently the thick open section composite beams are used extensively as load carrying members and stiffeners of structural elements. However, most of studies on thick composite beams are limited only to closed section beams. In this study, an open cross-section thick-walled composite beam model which includes coupled stiffness, transverse shear, and warping effects is suggested and the deflections associated with the thick-walled composite beams and thin-walled composite beams are obtained and compared with the finite element analysis results.

• Toxicological Research
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• 제22권2호
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• pp.135-144
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• 2006

This study was performed to evaluate repeated-dose toxicities of STB-HO-BM in Sprague-Dawley rats. STB-HO-BM was administered orally to rats at dose levels of 0, 100, 300 and 1,000 mg/kg/day for 13 weeks. In recent study, there were no dose related changes in mortality, clinical signs, body weight changes, food and water consumption, opthalmoscopy, organ weights, urine analysis, hematological findings, and biochemical examination of all animals treated with STB-HO-BM. Gross and histopathological findings revealed no evidence of specific toxicity related to STB-HO-BM. These results suggest that the oral no observed adverse effect level (NOAEL) of STB-HO-BM may be over 1,000 mg/kg in rats.

• Journal of Pharmaceutical Investigation
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• 제1권1호
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• pp.30-33
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• 1971

Comparative studies were made on the analgesic effect of salicylamide, used individually and combined with parasympatholytics (propantheline and atropine) and antihistaminics (tripelennamine, diphenhydramine) as regards the analgesic effect (in thermal contact method) were examined by its oral administration with each combined drug to mouse (three assumption cross-over test), and the following effects were found. 1. The increasing order of the parasympatholytics to the analgesic effect of salicylamide is as follows: propantheline>atropine. 2. The increasing order of the antihistaminics to the analgesic effect of salicylamide is as follows: chlorpheniramine>diphenhdramine>tri pelennamine. In the ratio '1 : 1' salicylamide to parasympatholytics and antihistaminics, the analgesic effect of salicylamide was more increase than the other ratio in this study.