• Title/Summary/Keyword: cox's proportional hazard model

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Factors Associated with Failure in The Continuity of Smoking Cessation Among 6 Month's Smoking Cessation Succeses in the Smoking Cessation Clinic of Public Health Center (보건소 금연클리닉 6개월 금연성공자의 금연지속 실패 요인)

  • Choi, Hyeon-Soon;Sohn, Hae-Sook;Kim, Yun-Hee;Lee, Myeong-Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.10
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    • pp.4653-4659
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    • 2012
  • This study was performed to investigate the factors related failure in continuity of smoking cessation among persons who were initially successful in quitting smoking for at least 6 months in smoking cessation clinic of public health center. Data were collected with the telephone questionnaire survey and the registered cards from 347 of 6 months quitters from 2006 to 2008 year. Data were analyzed by life table method and Cox-proportional hazard model. In Cox-proportional hazard model, Eup Myeon of residence(HR 2.50, 95% CI 1.69-3.68), without chronic diseases(HR 1.92, 95% CI 1.21-3.04), without another smoker in household(HR 1.93, 95% CI 1.21-3.09) and usage of supplement agent(HR 2.17, 95% CI 1.01-4.68) were independently associated with the failure in continuing to stay smoke-free. The cumulative rate of failure in the continuity of smoking cessation was 28.6% at 6 month and 36.1% at 24 month. For operating a clinic program for smoking cessation, Public health center should makes strategies that a person is continuing smoking cessation for over 6 months after the first 6 momth's smoking cessation.

Survival Factors among Medical Intensive Care Unit Patients with Carbapenemas-Producing Enterobacteriaceae (카바페넴분해효소 생성 장내세균속균종(CPE)이 획득된 내과계 중환자실 환자의 생존 영향 요인)

  • Choi, Ji Eun;Jeon, Mi Yang
    • Journal of Korean Biological Nursing Science
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    • v.22 no.4
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    • pp.249-259
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    • 2020
  • Purpose: Carbapenemase-producing Enterobacteriaceae (CPE) are associated with considerable mortality. This study was aimed to identify survival factors among medical care unit patients with CPE. Methods: We conducted a retrospective cohort; data were collected from September 2017 to June 2019 through electronic medical records. The data collected were general characteristics, disease-related characteristics, severity-related characteristics, and treatment-related characteristics. Data were analyzed based on frequency, mean, standard deviation, Chi-square test, Fisher's exact test, t-test, Pearson's correlation coefficient, and Cox proportional hazard model using SPSS/WIN 21.0 program. Results: Seventy-seven patients were included (59 survivors and 18 deceased) in the study. Univariate analysis identified factors for survival associated with acquired CPE as age (t= -1.56, p= .037), simplified acute physiology 3 (SAPS3) score of admission date (t= -2.85, p= .006), Glasgow coma scale (GCS) of CPE acquisition date (t= 2.38, p= .020), artery catheter at CPE acquisition date (χ2= 4.58, p= .032), vasoconstrictor agents use at CPE acquisition date (χ2= 6.81, p= .009), platelet at CPE acquisition date (t= 2.27, p= .025), lymphocyte at CPE acquisition date (t= 2.01, p= .048), calcium at CPE acquisition date (t= 2.68, p= .009), albumin at CPE acquisition date (t= 2.29, p= .025), and creatinine at CPE acquisition date (t= 2.24, p= .028). Multivariate Cox proportional hazard model showed that GCS at CPE acquisition date (HR= 1.14, 95% CI= 1.05-1.22), lymphocyte at CPE acquisition date (HR= 1.05, 95% CI= 1.00-1.10), and creatinine at CPE acquisition date (HR= 1.25, 95% CI= 1.04-1.49) were independent survival factors among medical intensive care unit patients with CPE. Conclusion: Based on the study results, it is necessary to develop nursing interventions that can aid in the management of patients with CPE and identify their effects.

Study on Commuting Travel Time devided by Life Cycle: In Gyeonggi-Do Case (생애주기별 통근통행시간 영향요인 분석: 경기도를 중심으로)

  • Bin, Mi-Young;Chung, Eui-Seok;Park, Hyoung-Won
    • Journal of Korean Society of Transportation
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    • v.30 no.3
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    • pp.71-82
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    • 2012
  • This study analyzed factors affecting daily travel times at each stage of commuters' life cycle. In this study, travel times were dealt with in the context of trip chain. That is, the travel time was defined as the total amount of time commuters had spent to move for daily activities from leaving to coming back home. A commuter's life cycle was divided into 6 stages on a basis of both householder's age and family type: i.e., the unmarried youth period, the family forming period, the children education period, the children youth period, the children independence period, and the aged period. Variables such as commuting times, home-based trip cycle recurrences, and the number of stops differed for each stage of life cycle, the latter of which represents how many places a commuter dropped by during a trip cycle. Several factors were found to affect commuting times at each stage of life cycle as a result of applying a Cox proportional hazard model. The empirical study was conducted using 2010' household travel survey data collected from Gyeonggi-do.

A Longitudinal Look at Economically Active Population Survey and Household Income and Expenditure Survey: Potential and Limitation (횡단조사자료 종단화의 가치와 한계: 경제활동인구조사와 도시가계조사)

  • Lee, Ji-Youn;Kim, Jin
    • Korea journal of population studies
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    • v.29 no.3
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    • pp.159-188
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    • 2006
  • This study attempts to create a longitudinal dataset by linking tdata on the identical individuals across the monthly sample household management lists of the Economically Active Population Survey(EAPS) and the Household Income and Expenditure Survey(HIES). Using the data constructed through such process, the study also tryies to analyze the duration of longitudinal responses and the characteristics of nonrespondents. Between 1998 and 2002, longitudinal response rates had declined to 46% of total EAPS and 34% of total HIES. The fact that nonresponse was not a random phenomenon leads to concerns about the representativeness of the remaining sample. Using Cox's proportional hazard model the study revealed that the duration of longitudinal responses is affected by the ownership of house and the age of the respondent.

Association between Health Risk Factors and Mortality over Initial 6 Year Period in Juam Cohort (주암 코호트에서 초기 6년간 건강위험인자와 사망의 관련성)

  • Kim, Sang-Yong;Lee, Su-Jin;Sohn, Seok-Joon;Choi, Jin-Su
    • Journal of agricultural medicine and community health
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    • v.32 no.1
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    • pp.13-26
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    • 2007
  • Objectives: This study was conducted to investigate the association between health risk factors and mortality in Juam cohort. Methods: The subjects were 1,447 males and 1,889 females who had been followed up for 68.5 months to 1 January 2001. Whether they were alive or not was confirmed by the mortality data of the National Statistical Office. A total of 289 persons among them died during the follow-up period. The Cox's proportional hazard regression model was used for survival analysis. Results: Age, type of medical insurance, self cognitive health level, habit of alcohol drinking, smoking, exercise and BMI level were included in Cox's proportional hazard model by gender. The hazard ratio of age was 1.07(95% CI: 1.05-1.10) in men, 1.09(95% CI: 1.06-1.12) in women. The hazard ratio of medical aid(lower socioeconomic state) was 1.43(95% CI 1.02-2.19) in women. The hazard ratios of current alcohol drinking and current smoking were respectively 1.69(95% CI: 1.01-2.98), 1.52(95% CI: 1.02-2.28) in women. The hazard ratio of underweight was 1.56(95% CI 1.08-2.47) in men. The hazard ratios of underweight, normoweight, overweight, and obesity were respectively 1.63(95% CI: 1.02-2.67), 1.0(referent), 0.62(95% CI: 0.32-1.63), 1.27(95% CI: 0.65-3.06), which supported the U-shaped relationship between body mass index and mortality among the men over 65. Conclusions: The health risk factors increasing mortality were age, underweight in male, age, lower socioeconomic state, current alcohol drinking, current smoking in female. To evaluate long-term association between health risk factors and mortality, further studies need to be carried out.

Determinants of Termination of Anti-dumping Measures: The Case of Korea

  • Rhee, Jin Woo;Jang, Yong Joon
    • East Asian Economic Review
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    • v.26 no.2
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    • pp.95-117
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    • 2022
  • This paper empirically examines what factors affected the termination of anti-dumping measures in Korea during the 2006-2019 period. Employing a meticulous literature review, the paper investigates the WTO's and Korea's rules on the termination of anti-dumping measures and sets up the related variables in the Cox proportional hazards model. The empirical results show that the GDP growth rate, employment, and trade competitiveness in domestic industries had positive effects on the hazard of the termination of AD measures, while free trade agreements had negative effects. By industry, the hazard of the termination of AD measures was less prominent in the steel industry, while it was more prominent in the machinery industry. These results imply that AD measures in Korea had the properties of a proper trade remedy policy and, at the same time, a protectionism tool to sustain its domestic industries, depending on industrial characteristics and other trade policies.

Timing and Risk Factors of Adoption for Legally-Free Foster Children after Having Parental Rights Terminated in the U. S. (미국 위탁아동의 친권상실선고 이후 입양 결정요인에 관한 생존분석)

  • Song, Min-Kyoung
    • Korean Journal of Social Welfare
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    • v.59 no.1
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    • pp.301-327
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    • 2007
  • The purpose of this study is to examine the timing and the risk factors associated with the adoption of legally-free foster children. The sample of the study was drawn from foster care files of Adoption and Foster Care Analysis and Reporting System(AFCARS) in 32 states between October 1998 (FY 1999) and September 2002(FY 2002). The timing post-TPR to adoption was examined by plotting the Kaplan-Meier cumulative hazard function for adoption and by plotting the KM hazard functions stratified by child's race and child's age at TPR. Cox proportional-hazards regression analysis was used to identify risk factors for adoption of legally-free foster children after TPR. The hazard of adoption was very low immediately after TPR but increased steadily starting at 3 months and then declined after 20 months. The cumulative hazard functions for White non-Hispanic children and Black non-Hispanic children crossed over at 13 months after TPR. Racial minority status, older age, and disability were negatively associated with the hazard of adoption. Physical abuse, sexual abuse had the lower hazard for adoption compared by neglect. Caretaker's inability to cope had the slightly lower hazard for adoption whereas inadequate housing showed the slightly greater hazard for adoption. Characteristics of foster care services turned into be powerful predictors of adoption. Specifically, legally-free children placed in pre-adoptive homes, those who shared the same racial/ethnic background with their foster caretakers, and those who were placed in two-parent families have a greater likelihood of adoption. The findings highlight the importance of foster care service provisions after TPR to facilitate adoption of legally-free foster children. Furthermore, a more substantial resources and targeted support for foster children who experience physical abuse and sexual abuse in need of adoption should be provided for moving the foster children into permanency.

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Prediction of Life Expectancy for Terminally Ill Cancer Patients Based on Clinical Parameters (말기 암 환자에서 임상변수를 이용한 생존 기간 예측)

  • Yeom, Chang-Hwan;Choi, Youn-Seon;Hong, Young-Seon;Park, Yong-Gyu;Lee, Hye-Ree
    • Journal of Hospice and Palliative Care
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    • v.5 no.2
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    • pp.111-124
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    • 2002
  • Purpose : Although the average life expectancy has increased due to advances in medicine, mortality due to cancer is on an increasing trend. Consequently, the number of terminally ill cancer patients is also on the rise. Predicting the survival period is an important issue in the treatment of terminally ill cancer patients since the choice of treatment would vary significantly by the patents, their families, and physicians according to the expected survival. Therefore, we investigated the prognostic factors for increased mortality risk in terminally ill cancer patients to help treat these patients by predicting the survival period. Methods : We investigated 31 clinical parameters in 157 terminally ill cancer patients admitted to in the Department of Family Medicine, National Health Insurance Corporation Ilsan Hospital between July 1, 2000 and August 31, 2001. We confirmed the patients' survival as of October 31, 2001 based on medical records and personal data. The survival rates and median survival times were estimated by the Kaplan-Meier method and Log-rank test was used to compare the differences between the survival rates according to each clinical parameter. Cox's proportional hazard model was used to determine the most predictive subset from the prognostic factors among many clinical parameters which affect the risk of death. We predicted the mean, median, the first quartile value and third quartile value of the expected lifetimes by Weibull proportional hazard regression model. Results : Out of 157 patients, 79 were male (50.3%). The mean age was $65.1{\pm}13.0$ years in males and was $64.3{\pm}13.7$ years in females. The most prevalent cancer was gastric cancer (36 patients, 22.9%), followed by lung cancer (27, 17.2%), and cervical cancer (20, 12.7%). The survival time decreased with to the following factors; mental change, anorexia, hypotension, poor performance status, leukocytosis, neutrophilia, elevated serum creatinine level, hypoalbuminemia, hyperbilirubinemia, elevated SGPT, prolonged prothrombin time (PT), prolonged activated partial thromboplastin time (aPTT), hyponatremia, and hyperkalemia. Among these factors, poor performance status, neutrophilia, prolonged PT and aPTT were significant prognostic factors of death risk in these patients according to the results of Cox's proportional hazard model. We predicted that the median life expectancy was 3.0 days when all of the above 4 factors were present, $5.7{\sim}8.2$ days when 3 of these 4 factors were present, $11.4{\sim}20.0$ days when 2 of the 4 were present, and $27.9{\sim}40.0$ when 1 of the 4 was present, and 77 days when none of these 4 factors were present. Conclusions : In terminally ill cancer patients, we found that the prognostic factors related to reduced survival time were poor performance status, neutrophilia, prolonged PT and prolonged am. The four prognostic factors enabled the prediction of life expectancy in terminally ill cancer patients.

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Predicting the Retention of University Freshmen Using Peer Relationships (대학 신입생들의 교우관계를 통한 학업유지 예측)

  • Lee, Yeonju;Choi, Sungwon
    • Korean Journal of School Psychology
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    • v.18 no.1
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    • pp.31-48
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    • 2021
  • The purpose of this study was to determine whether the retention of university freshmen could be predicted using their peer relationships in a specific department. In this study, retention was defined as a student staying enrolled in their university for a certain period of time. Social relationships are formed through interaction between people, so both students' self-perceptions and others' perceptions of them must be accounted for, so we used a social network analysis that did so. We examined social networks visualizations that allowed for a rich interpretation of numerical information. Participants in this study were freshmen who enrolled in an undergraduate program in 2017, 2018, or 2019. We used the name generator method to determine how quantitative friendship network variables predicted the academic retention up to the first semester of 2020. Cox proportional hazard model analysis showed that the weighted indegree centrality with intimacy positively predicted retention. The results of this study can be used to identify and conduct interventions for students who may be likely to disenroll. However all of the students did not participate in the department, it was difficult to examine their entire peer networks. Thus, this study's results cannot be generalized because the participants are students of a specific major, so further research is needed to produce more generalizable results.

Analysis of Nested Case-Control Study Designs: Revisiting the Inverse Probability Weighting Method

  • Kim, Ryung S.
    • Communications for Statistical Applications and Methods
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    • v.20 no.6
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    • pp.455-466
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    • 2013
  • In nested case-control studies, the most common way to make inference under a proportional hazards model is the conditional logistic approach of Thomas (1977). Inclusion probability methods are more efficient than the conditional logistic approach of Thomas; however, the epidemiology research community has not accepted the methods as a replacement of the Thomas' method. This paper promotes the inverse probability weighting method originally proposed by Samuelsen (1997) in combination with an approximate jackknife standard error that can be easily computed using existing software. Simulation studies demonstrate that this approach yields valid type 1 errors and greater powers than the conditional logistic approach in nested case-control designs across various sample sizes and magnitudes of the hazard ratios. A generalization of the method is also made to incorporate additional matching and the stratified Cox model. The proposed method is illustrated with data from a cohort of children with Wilm's tumor to study the association between histological signatures and relapses.