Purpose: Exclusive breastfeeding promotes gut microbial compositions associated with lower rates of metabolic and autoimmune diseases. Its cessation is implicated in increased microbiome-metabolome discordance, suggesting a vulnerability to dietary changes. Formula supplementation is common within our low-income, ethnic-minority community. We studied exclusively breastfed (EBF) neonates' early microbiome-metabolome coupling in efforts to build foundational knowledge needed to target this inequality. Methods: Maternal surveys and stool samples from seven EBF neonates at first transitional stool (0-24 hours), discharge (30-48 hours), and at first appointment (days 3-5) were collected. Survey included demographics, feeding method, medications, medical history and tobacco and alcohol use. Stool samples were processed for 16S rRNA gene sequencing and lipid analysis by gas chromatography-mass spectrometry. Alpha and beta diversity analyses and Procrustes randomization for associations were carried out. Results: Firmicutes, Proteobacteria, Bacteroidetes and Actinobacteria were the most abundant taxa. Variation in microbiome composition was greater between individuals than within (p=0.001). Palmitic, oleic, stearic, and linoleic acids were the most abundant lipids. Variation in lipid composition was greater between individuals than within (p=0.040). Multivariate composition of the metabolome, but not microbiome, correlated with time (p=0.030). Total lipids, saturated lipids, and unsaturated lipids concentrations increased over time (p=0.012, p=0.008, p=0.023). Alpha diversity did not correlate with time (p=0.403). Microbiome composition was not associated with each samples' metabolome (p=0.450). Conclusion: Neonate gut microbiomes were unique to each neonate; respective metabolome profiles demonstrated generalizable temporal developments. The overall variability suggests potential interplay between influences including maternal breastmilk composition, amount consumed and living environment.
To ensure the flutter stability of three-tower suspension bridges under skew wind, by using the computational procedure of 3D refined flutter analysis of long-span bridges under skew wind, in which structural nonlinearity, the static wind action(also known as the aerostatic effect) and the full-mode coupling effect etc., are fully considered, the flutter stability of a three-tower suspension bridge-the Taizhou Bridge over the Yangtze River in completion and during the deck erection is numerically investigated under the constant uniform skew wind, and the influences of skew wind and aerostatic effects on the flutter stability of the bridge under the service and construction conditions are assessed. The results show that the flutter critical wind speeds of three-tower suspension bridge under service and construction conditions fluctuate with the increase of wind yaw angle instead of a monotonous cosine rule as the decomposition method proposed, and reach the minimum mostly in the case of skew wind. Both the skew wind and aerostatic effects significantly reduce the flutter stability of three-tower suspension bridge under the service and construction conditions, and the combined skew wind and aerostatic effects further deteriorate the flutter stability. Both the skew wind and aerostatic effects do not change the evolution of flutter stability of the bridge during the deck erection, and compared to the service condition, they lead to a greater decrease of flutter critical wind speed of the bridge during deck erection, and the influence of the combined skew wind and aerostatic effects is more prominent. Therefore, the skew wind and aerostatic effects must be considered accurately in the flutter analysis of three-tower suspension bridges.
To accurately calculate the heating distribution of the fast reactor, a neutron-photon library in MATXS format named Knight-B7.1-1968n × 94γ was processed based on the ENDF/B-VII.1 library for ultrafine groups. The neutron cross-section processing code MGGC2.0 was used to generate few-group neutron cross sections in ISOTXS format. Additionally, the self-developed photon cross-section processing code NGAMMA was utilized to generate photon libraries for neutron-photon coupled heating calculations, including photo-atom cross sections for the ISOTXS format, prompt photon production cross sections, and kinetic energy release in materials (KERMA) factors for neutrons and photons, and the self-shielding effect from the capture and fission cross sections of neutron to photon have been taken into account when the photon source generated by neutron is calculated. The interface code GSORCAL was developed to generate the photon source distribution and interface with the DIF3D code to calculate the neutron-photon coupling heating distribution of the fast reactor core. The neutron-photon coupled heating calculation route was verified using the ZPPR-9 benchmark and the RBEC-M benchmark, and the results of the coupled heating calculations were analyzed in comparison with those obtained from the Monte Carlo code MCNP. The calculations show that the library was accurately processed, and the results of the fast reactor neutron-photon coupled heating calculations agree well with those obtained from MCNP.
Lee, Dai Woon;Kim, Jin Young;Park, Young Hun;Moon, Myeong Hee
Analytical Science and Technology
/
v.7
no.1
/
pp.33-39
/
1994
The purpose on this study was to develop a new improved chromatographic method for determination of trace phenols from environmental waste water. The research was carried out with selected 8 phenols, and solid-phase extraction was employed as sample pretreatment method. The coupling of XAD-4 and Dowex $1{\times}8$ resin as preconcentration column increased the selectivities toward interferences coexisted in matrix. Automation was accomplished with on-line process of pretreatment and HPLC system. After elution of sample through XAD-4 column, phenols were adsorbed by dispersion force, then displaced from it by ACN basified, simultaneously and selectively readsorbed via anion exchange on Dowex $1{\times}8$. Dowex $1{\times}8$ column was washed by water. Phenols readsorbed were removed from Dowex $1{\times}8$ column by a minimum volumn of methanol containing HCl. Each pretreatment step was connected by switching valves and the eluate was directly on-line injected to obtain fast and reliable results into the HPLC. Recovery of phenols was greater than 90%. To examine utility of this method, analysis of phenols from laboratory waste water sample which was added some organic pollutants to find with phenols on environmental waste water were also accomplished without their interference effects.
Jo, Hyeong-Je;Jun, Kyu-Myung;Min, Dea-Kee;Kim, Jong-Won;Beak, Jong-Hoon
Journal of Korean Tunnelling and Underground Space Association
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v.20
no.1
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pp.145-160
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2018
Long subsea tunnel is subject to many restrictions in terms of spatial limitation when vertical or inclined shafts are built for tunnel ventilation. So, the construction of some artificial island is required to provide ventilation. But, because of construction difficulty and cost increase, it is necessary to minimize the artificial island construction. As a result, ventilation distance become longer and supply airflow becomes excessive due to air leakage, So, duct mounting for temporary ventilation is impossible or fan pressure and power increase exponentially. Therefore, in order to build a long subsea tunnel, it is necessary to overcome these practical problems and to develop technical solution that can keep the comfortable condition of tunnel environment during construction. In previous study, we have found that air leakage is the key factor in solving these problems and experimental results show that the new connection method has a leakage rate of about $1.46mm^2/m^2$ (Jo et al., 2017). In this study, we present the experimental results of the measurement of the leakage rate of the prototype with the new connection method, and analyze experimentally the improvement of the leakage rate when applying the flexible cover inside the duct to improve the leakage performance of the existing connection method.
In modern distributed enterprise applications that have multilayered architecture, business entities are a kind of crosscutting concerns running through service components that implements business logic in each layer. When business entities are modified, service components related to them should also be modified so that they can deal with those business entities with new types, even though their functionality remains the same. Our previous paper proposed what we call the DTT (Data Type-Tolerant) component model to efficiently process the variability of business entities, which are data externalized from service components. While the DTT component model, by removing direct coupling between service components and business entities, exempts the need to rewrite service components when business entities are modified, it incurs the burden of implementing data type converters that mediate between them. To solve this problem, this paper proposes a method to use ontology as the metadata of both SCDTs (Self-Contained Data Types) in service components and business entities, and a method to generate data type converter code using the ontology. This ontology-based DTT component model greatly enhances the reusability of service components and the efficiency in processing data variability by allowing the computer to automatically generate data type converters without error.
Rapid industrial development has led to a serious problem of pollution in the industrial sector. With the increasing social need for environmental protection, research on air pollution prevention equipment for reducing pollutants in industrial processes is actively being undertaken. The deterioration of existent, installed facilities, their increased emission rates, and the strengthening of the effluent quality standards make complying with permissible emission standards difficult. In fact, installing new electric precipitators or complementing existent facilities is inevitable. The expansion and complementation of the installed electrical precipitators have led to improvements in dust collection efficiency, shorter working times, and lower costs. Because of its easy installation and simple manufacturing process, the production method with the discharge electrode of an electric precipitator is widely used. The following conclusions were reached by classifying discharge electrodes into four types based on the production method and mutually comparing them by their dust collection efficiency. None of the four types used in this study were damaged by impact. However, we were able to confirm some strain from the compression sites of both type A and type B. Both type B and type C are expected to have greater dust collection efficiencies than the other models due to their large vibration transmissibility. Moreover, the high vibrational energy is expected to cause rapping damage during its operation. Particularly, in the case of type B, some of the strain was found at the end of the compression site. The coupling schemes of both type C and type D are out of vibration transmissibility. On the other hand, the ability to maintain straightness and solidity of the side is regarded as outstanding and stable. Type D has outstanding on-site workability, considering the presence of locking, structural stability, and work conditions. From these experiments, we determined that type C is the most ideal connection method of discharge electrode, considering its construction period of renovation. Type C is inferior to type D with regard to on-site workability. However, type C has outstanding dedusting transmission with regard to the straightness, solidity maintenance, and vibration of shearing stress.
In this paper, it is about to non-contact wireless power transmission according to various conditions of self induction principle between the two planar coils at a transmission unit and a receiving unit based on the theory of wireless power transmission. The experiments are occurred in order to power transfer of noncontact method from designed wireless circuits in the primely coil and secondary coil, and the applying to Half Bridge Resonant converter transmission unit and receiving unit. and that were able to prepared circumstance to calculate of the output voltage and power source. The main power of the inductive coupling the resonant converter at the transmission unit is converted electrical energy using the solar cell module and artificial light source (halogen lamp) as a replace light and received 24 V power supply from solar power was used a input power source for the wireless power transmission device. Experimental results, to received of power is used to illuminate the lighting and to charge the battery in receiving circuit.And the wireless power transmission efficiency measured at the output side of the transmission unit is obtained about 70% to 89% compared to input power of receiving unit.In addition, efficiency were tested through ID verification method and comparing the phase difference between the voltage when foreign substances interfere with wireless power transmission.
Lee Seong Kon;Cho Seong-Jun;Song Yoonho;Chung Seung-Hwan
Geophysics and Geophysical Exploration
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v.5
no.1
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pp.23-32
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2002
Capacitively-coupled resistivity (CCR) system is known to be very useful where galvanic contact to earth is impossible, such as the area covered with thick ice, snow, concrete or asphalt. This system injects current non-galvanically, i.e., capacitively to earth through line antenna and measures potential difference in a same manner. We derived geometric factor for two types of antenna configuration and presented the method of processing and converting the data obtained with CCR system suitable to conventional resistivity inversion analysis. The CCR system, however, has limitations on use at conductive area or electrically noisy area since it is very difficult to inject sufficient current to earth with this system as with conventional resistivity system. This causes low SM ratio when acquiring data with CCR system and great care must be taken in acquiring data with this system. Additionally the uniform contact between line antennas and earth is also crucial factor to obtain good S/N ratio data. The CCR method, however, enables one to perform continuous profiling over a survey line by dragging entire system and thus will be useful in rapid investigation of conductivity distribution in shallow subsurface.
Lee, Gye Hee;Hong, Kwan Young;Lee, Eun Haeng;Kim, Jae Min
Journal of the Computational Structural Engineering Institute of Korea
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v.27
no.2
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pp.95-102
/
2014
In this paper, a coupling scheme for applying finite element analysis(FEA) programs, such as, LS-DYNA and MIDAS/Civil, to a nonlinear soil structure interaction analysis by the boundary reaction method(BRM) is presented. With the FEA programs, the structure and soil media are discretized by linear or nonlinear finite elements. To absorb the outgoing elastic waves to unbounded soil region as much as possible, the PML elements and viscous-spring elements are used at the outer FE boundary, in the LS-DYNA model and in MIDAS/Civil model, respectively. It is also assumed that all the nonlinear elements in the problem are limited to structural region. In this study, the boundary reaction forces for the use in the BRM are calculated using the KIESSI-3D program by solving soil-foundation interaction problem subjected to incident seismic waves. The effectiveness of the proposed approach is demonstrated with a linear SSI seismic analysis problem by comparing the BRM solution with the conventional SSI solution. Numerical comparison indicates that the BRM can effectively be applied to a nonlinear soil-structure analysis if motions at the foundation obtained by the BRM for a linear SSI problem excluding the nonlinear structure is conservative.
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