• Title/Summary/Keyword: coupled system

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Effects of Paeoniae Radix Aqua-Acupuncture Solution on Tert-Butyl Hydroperoxide Induced Lipid Peroxidation and Antioxidative Enzymes in Cultured Rat Liver Cells (작약 약침액이 tert-butyl hydroperoxide 로 유도된 흰쥐 배양 간세포의 지질과산화반응 및 항산화효소 활성에 미치는 영향)

  • Moon, Jin-Young
    • Journal of Acupuncture Research
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    • v.17 no.3
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    • pp.176-187
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    • 2000
  • Objectives : This study was purposed to investigate the antioxidative effects of Paeoniae radix aqua-acupuncture solution(PR) on culture liver cell system, lipid peroxidation and antioxidative enzyme activities in tert-butyl hydroperoxide(t-BHP) treatmented conditions. Methods : Cultured normal rat liver cell(Ac2F) were prepared and incubated with or without PR(at 2% volume in culture medium). After 16~18hr, cells placed in DMEM medium without serum, and then incubated with 1mM t-BHP for 2hr. Viable cells were detected by MTT assay, and the levels of lipid peroxide(LPO) were measured by TBA method. And catalase activity was measured as the decrease in hydrogen peroxide absorbance at 240nm on spectrophotometer using 30mM hydrogen peroxide. Superoxide dismutase(SOD) were assayed by recording the inhibition of nitro blue tetrazolium reduction with xanthine and xanthine oxidase. Glutathione peroxidase(GPX) activity was determined by the modified coupled assay developed by Paglia and Lawrence. The reaction was started by addition of 2.2mM hydrogen peroxide as substrate. The change in absorbance at 340nm was measured for 1min on spectrophotometer. Glutathione-S-transferase(GST) activity was assayed with CDNB as substrate and enzyme activity of GST towards the glutathione conjugation of CDNB. Results : Cell killing was significantly enhanced by addition of t-BHP compared to those of untreated group. PR pretreated cell resisted the toxic effects of t-BHP. LPO levels of t-BHP treatment group were significantly higher than other groups. This increased level was significandy reduced by PR pretreatment. The t-BHP treatment resulted in a decrease of catalase, GPX and GST activities. By contrast, PR pretreatment markedly increased compare to those of untreated groups. Conclusions : T-BHP which can produce intracellular free radical was used for inducer of the peroxidation of cellular lipids. PR protected the cell death induced by t-BHP and significantly increased cell viabiliry in the normal rat liver cell, and showed effective inhibition of lipid peroxidation, and elevations of catalase, GPX and GST activities. These results suggested that PR might play a protective role in lipid peroxidation by free radicals.

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A Design of 1.42 - 3.97GHz Digitally Controlled LC Oscillator (1.42 - 3.97GHz 디지털 제어 방식 LC 발진기의 설계)

  • Lee, Jong-Suk;Moon, Yong
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.49 no.7
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    • pp.23-29
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    • 2012
  • The LC-based digitally controlled oscillator (LC-DCO), a key component of the all digital phase locked loop (ADPLL), is designed using $0.18{\mu}m$ RFCMOS process with 1.8 V supply. The NMOS core with double cross-coupled pair is chosen to realize wide tuning range, and the PMOS varactor pair that has small capacitance of a few aF and the capacitive degeneration technique to shrink the capacitive element are adopted to obtain the high frequency resolution. Also, the noise filtering technique is used to improve phase noise performance. Measurement results show the center frequency of 2.7 GHz, the tuning range of 2.5 GHz and the high frequency resolution of 2.9 kHz ~7.1 kHz. Also the fine tuning range and the current consumption of the core could be controlled by using the array of PMOS transistors using current biasing. The current consumption is between 17 mA and 26 mA at 1.8V supply voltage. The proposed DCO could be used widely in various communication system.

Magnetic Exchange Interactions in a 2D Grid-like Copper(II) Polymer with Bridging End-on Cyanato and Pyrazine Ligands: A DFT Study

  • Kang, Dae-Bok
    • Bulletin of the Korean Chemical Society
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    • v.31 no.6
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    • pp.1704-1710
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    • 2010
  • The structure of a 2D grid-like copper(II) complex [Cu$(NCO)_2$(pyz)](pyz=pyrazine) (1) consists of 1D chains of Cu-pyz units connected by double end-on (EO) cyanato bridges. Each Cu(II) ion has a distorted octahedral coordination, completed by the four EO cyanato and two pyrazine ligands. Magnetic interactions through EO cyanato and pyrazine bridges in 1 are discussed on the basis of DFT broken-symmetry calculations at the B3LYP level. For model dicopper(II) complexes I (bridged by cyanato) and II (bridged by pyrazine), electronic structure calculations reproduce very well the experimental couplings for the S = 1/2 ferromagnetic and antiferromagnetic exchange-coupled 2D system: the calculated exchange parameters J are +1.25 $cm^{-1}$ and -3.07 $cm^{-1}$ for I and II, respectively. The $\sigma$ orbital interactions between the Cu $x^2-y^2$ magnetic orbitals and the nitrogen lone-pair orbitals of pyrazine are analyzed from the viewpoint of through-bond interaction. The energy splitting of 0.106 eV between two SOMOs indicates that the superexchange interaction should be antiferromagnetic in II. On the other hand, there are no bridging orbitals that efficiently connect the two copper(II) magnetic orbitals in I because the HOMOs of the basal-apical NCO bridge do not play a role in the formation of overlap interaction pathway. The energy separation in the pair of SOMOs of I is calculated to be very small (0.054 eV). This result is consistent with the occurrence of weakly ferromagnetic properties in I.

An Investigation into the Hull-Girder Vibration Analysis of RO/RO Car/Truck Carriers (자동차운반선(自動車運搬船) 선체저차진동(船體低次振動)의 해석(解析))

  • K.C.,Kim;D.S.,Cho;J.H.,Chung;J.W.,Kang;S.J.,Moon;J.H.,Woo
    • Bulletin of the Society of Naval Architects of Korea
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    • v.27 no.1
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    • pp.35-44
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    • 1990
  • Most of the medium-size ships are powered by large-bore, long-stroke, slow-speed and two-stroke diesel engines in order to improve the fuel efficiency. Such a propulsion plant develops low-frequency excitation forces/moments of significant magnitude. A RO/RO car/truck carrier is also one of the cases. In this paper, the rational methods for analysis of vertical and coupled horizontal-torsional vibrations are presented. Taking account of unusual characteristics of the hull form and structural systems, the emphasis is put on modelling methods based on beam analogy, calculation of system parameters such as added mass and its center, polar added-mass moment of inertia, shear coefficient of hull sections and coupling degree in antisymmetric modes, and modal analysis of forced vibrations.

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Accuracy of various imaging methods for detecting misfit at the tooth-restoration interface in posterior teeth

  • Francio, Luciano Andrei;Silva, Fernanda Evangelista;Valerio, Claudia Scigliano;Cardoso, Claudia Assuncao e Alves;Jansen, Wellington Correa;Manzi, Flavio Ricardo
    • Imaging Science in Dentistry
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    • v.48 no.2
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    • pp.87-96
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    • 2018
  • Purpose: The present study aimed to evaluate which of the following imaging methods best assessed misfit at the tooth-restoration interface: (1) bitewing radiographs, both conventional and digital, performed using a photostimulable phosphor plate (PSP) and a charge-coupled device (CCD) system; (2) panoramic radiographs, both conventional and digital; and (3) cone-beam computed tomography (CBCT). Materials and Methods: Forty healthy human molars with class I cavities were selected and divided into 4 groups according to the restoration that was applied: composite resin, composite resin with liner material to simulate misfit, dental amalgam, and dental amalgam with liner material to simulate misfit. Radiography and tomography were performed using the various imaging methods, and the resulting images were analyzed by 2 calibrated radiologists. The true presence or absence of misfit corresponding to an area of radiolucency in regions subjacent to the esthetic and metal restorations was validated with microscopy. The data were analyzed using a receiver operating characteristic (ROC) curve, and the scores were compared using the Cohen kappa coefficient. Results: For bitewing images, the digital systems (CCD and PSP) showed a higher area under the ROC curve (AUROC) for the evaluation of resin restorations, while the conventional images exhibited a larger AUROC for the evaluation of amalgam restorations. Conventional and digital panoramic radiographs did not yield good results for the evaluation of resin and amalgam restorations (P<.05). CBCT images exhibited good results for resin restorations(P>.05), but showed no discriminatory ability for amalgam restorations(P<.05). Conclusion: Bitewing radiographs (conventional or digital) should be the method of choice when assessing dental restoration misfit.

Characterization of Microstructure and Thermal property of Ash Deposits on Fire-side Boiler Tube

  • Bang, Jung Won;Lee, Yoon-Joo;Shin, Dong-Geun;Kim, Younghee;Kim, Soo-Ryong;Baek, Chul-Seoung;Kwon, Woo-Teck
    • Journal of the Korean Ceramic Society
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    • v.53 no.6
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    • pp.659-664
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    • 2016
  • Ash deposition of heat exchange boiler, caused mainly by accumulation of particulate matter, reduces heat transfer of the boiler system. Heat and mass transfer through porous media such as ash deposits mainly depend on the microstructure of deposited ash. Therefore, in this study, we investigated microstructural and thermal properties of the ash deposited on the boiler tube. Samples for this research were obtained from the fuel economizer tube in an industrial waste incinerator. To characterize microstructures of the ash deposit samples, scanning electron microscope (SEM), energy-dispersive spectroscopy (EDS), inductively coupled plasma optical emission spectroscopy (ICP-OES), X-ray diffraction (XRD) and BET analysis were employed. The results revealed that it had a porous structure with small particles mostly of less than a few micrometers; the contents of Ca and S were 19.3, 22.6% and 18.5, 18.7%, respectively. Also, the results showed that it consisted mainly of anhydrite ($CaSO_4$) crystals. - The thermal conductivities of the ash deposit sample obtained from the economizer tube in industrial waste incinerator were measured to be 0.63 and 0.54 W/mK at $200^{\circ}C$, which were about 100 times less than the thermal conductivity (61.32 W/mK) of the boiler tube itself, indicating that ash deposition on the boiler tube was closely related to a decrease in boiler heat transfer.

Spatial Index based on Main Memory for Web CIS (Web GIS를 위한 주기억 장치 기반 공간 색인)

  • 김진덕;진교홍
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2001.10a
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    • pp.191-194
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    • 2001
  • The availability of the inexpensive, large main memories coupled with the demand for faster response time are bringing a new perspective to database technology. The Web GIS used by u unspecified number of general public in the internet needs high speed response time and frequent data retrieval for spatial analysis rather than data update. Therefore, it is appropriate to use main memory as a underlying storage structures for the Web GIS data. In this paper, we propose a data representation method based on relative coordinates and the size of the MBR. The method is able to compress the spatial data widely used in the Web GIS into smaller volume of memory. We also propose a memory resident spatial index with simple mechanism for processing point and region queries. The performance test shows that the index is suitable for managing the skewed data in terms of the size of the index and the number of the MBR intersection check operations.

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Etch characteristics of TiN thin film adding $Cl_2$ in $BCl_3$/Ar Plasma ($BCl_3$/Ar 플라즈마에서 $Cl_2$ 첨가에 따른 TiN 박막의 식각 특성)

  • Um, Doo-Seung;Kang, Chan-Min;Yang, Xue;Kim, Dong-Pyo;Kim, Chang-Il
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.06a
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    • pp.168-168
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    • 2008
  • Dimension of a transistor has rapidly shrunk to increase the speed of device and to reduce the power consumption. However, it is accompanied with several problems like direct tunneling through the gate dioxide layer and low conductivity characteristic of poly-Si gate in nano-region. To cover these faults, study of new materials is urgently needed. Recently, high dielectric materials like $Al_2O_3$, $ZrO_2$, and $HfO_2$ are being studied for equivalent oxide thickness (EOT). However, poly-Si gate is not compatible with high-k materials for gate-insulator. Poly Si gate with high-k material has some problems such as gate depletion and dopant penetration problems. Therefore, new gate structure or materials that are compatible with high-k materials are also needed. TiN for metal/high-k gate stack is conductive enough to allow a good electrical connection and compatible with high-k materials. According to this trend, the study on dry etching of TiN for metal/high-k gate stack is needed. In this study, the investigations of the TiN etching characteristics were carried out using the inductively coupled $BCl_3$-based plasma system and adding $Cl_2$ gas. Dry etching of the TiN was studied by varying the etching parameters including $BCl_3$/Ar gas mixing ratio, RF power, DC-bias voltage to substrate, and $Cl_2$ gas addition. The plasmas were characterized by optical emission spectroscopy analysis. Scanning electron microscopy was used to investigate the etching profile.

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Study on the Performance Evaluation of the Explosive Bolt that has been Natural Aging (자연 노화된 폭발볼트의 성능 평가에 관한 연구)

  • Kim, Dongjin;Jeong, Donghee;Lee, Yeungjo;Lee, Youngwoo
    • Journal of the Korean Society of Propulsion Engineers
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    • v.21 no.3
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    • pp.84-90
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    • 2017
  • Explosive bolt is coupled in a variety of guided weapons and space projectiles, to perform the separation function. Thus, the role of the explosive bolt in guided weapons systems is very important, as it can cause failure of the entire system in the case of mission failure. For this reason, the design life prediction for explosive bolt is highly and frequently required recently, but its accurate prediction method has not been presented. In order to apply the existing accelerated aging process, we should know the activation energy and the acceleration factor of the explosive bolt. Since the information required for accelerated aging is not presently secured, it is difficult to predict the design life of explosive. Thus, in the present study, we have evaluated the performance of actual explosive bolts in the condition of natural aging over 10 years in order to present a minimum design life.

Field monitoring of the train-induced hanger vibration in a high-speed railway steel arch bridge

  • Ding, Youliang;An, Yonghui;Wang, Chao
    • Smart Structures and Systems
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    • v.17 no.6
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    • pp.1107-1127
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    • 2016
  • Studies on dynamic characteristics of the hanger vibration using field monitoring data are important for the design and evaluation of high-speed railway truss arch bridges. This paper presents an analysis of the hanger's dynamic displacement responses based on field monitoring of Dashengguan Yangtze River Bridge, which is a high-speed railway truss arch bridge with the longest span throughout the world. The three vibration parameters, i.e., dynamic displacement amplitude, dynamic load factor and vibration amplitude, are selected to investigate the hanger's vibration characteristics in each railway load case including the probability statistical characteristics and coupled vibration characteristics. The influences of carriageway and carriage number on the hanger's vibration characteristics are further investigated. The results indicate that: (1) All the eight railway load cases can be successfully identified according to the relationship of responses from strain sensors and accelerometers in the structural health monitoring system. (2) The hanger's three vibration parameters in each load case in the longitudinal and transverse directions have obvious probabilistic characteristics. However, they fall into different distribution functions. (3) There is good correlation between the hanger's longitudinal/transverse dynamic displacement and the main girder's transverse dynamic displacement in each load case, and their relationships are shown in the hysteresis curves. (4) Influences of the carriageway and carriage number on the hanger's three parameters are different in both longitudinal and transverse directions; while the influence on any of the three parameters presents an obvious statistical trend. The present paper lays a good foundation for the further analysis of train-induced hanger vibration and control.