• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.4
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• pp.1389-1408
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• 2021

Proof-of-Work (PoW) is the first and still most common consensus protocol in blockchain. But it is costly and energy intensive, aiming at addressing these problems, we propose a consensus algorithm named Proof-of-Work-and-Block-Compression (PoW-BC). PoW-BC is an improvement of PoW to compress blocks and adjust consensus parameters. The algorithm is designed to encourage the reduction of block size, which improves transmission efficiency and reduces disk space for storing blocks. The transaction optimization model and block compression model are proposed to compress block data with a smaller compression ratio and less compression/ decompression duration. Block compression ratio is used to adjust mining difficulty and transaction count of PoW-BC consensus protocol according to the consensus parameters adjustment model. Through experiment and analysis, it shows that PoW-BC improves transaction throughput, and reduces block interval and energy consumption.

• Toxicological Research
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• v.18 no.1
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• pp.65-71
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• 2002

A benchmark dose (BMD) approach has been evaluated us a replacement for the traditional NOAEL methodology currently being wed to assess the noncancer effects of toxicants. The endocrine disrupt-ing effect of endosulfan which showed decrement of sperm count and testicular testosterone level in animals, was currently reported. The amount of endosulfan used as pesticide in the country has been continuously increased. The aim of this study was to suggest the permissible intake level (PIL), corresponding to Accept-able Daily Intake (ADI), based on endocrine disrupting effect wing BMD. Various animal data were collected by consideration of critical effect showing endocrine disruption and an animal data for reproductive toxicity was selected. The Power model from BMD software for induction of $BMD_10$ having meaning which is the dose at the 95% lower confidence limit on a 10% response was used due to that the form of selected dose-response animal data was continuous data. The $BMD_10$ was estimated to be 0.393 mg/kg/day based on reproductive toxicity showing decrement of sperm count. The permissible intake level (PIL) was calculated by dividing the $BMD_10$ by the uncertainty factors of 100 with consideration of from animal to human and human variability. The PIL as 0.004 mg/kg/day was compared with traditional ADI as 0.006 mg/kg/day based on the incidence of marked progressive glomerulonephrosis and blood vessel aneurysm in males.

• JSTS:Journal of Semiconductor Technology and Science
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• v.17 no.2
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• pp.302-317
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• 2017

This paper proposes a new full adder design based on pass-transistor logic that offers ultra-low power dissipation and superior variability together with low transistor count. The pass-transistor logic allows device count reduction through direct logic realization, and thus leads to reduction in the node capacitances as well as short-circuit currents due to the absence of supply rails. Optimum transistor sizing alleviates the adverse effects of process variations on performance metrics. The design is subjected to a comparative analysis against existing designs based on Monte Carlo simulations in a SPICE environment, using the 22-nm CMOS Predictive Technology Model (PTM). The proposed ULP adder offers 38% improvement in power in comparison to the best performing conventional designs. The trade-off in delay to achieve this power saving is estimated through the power-delay product (PDP), which is found to be competitive to conventional values. It also offers upto 79% improvement in variability in comparison to conventional designs, and provides suitable scalability in supply voltage to meet future demands of energy-efficiency in portable applications.

• Journal of Environmental Science International
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• v.13 no.2
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• pp.175-180
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• 2004

A prompt gamma-ray neutron activation (PGNA) system was simulated by the Monte Carlo N-Particle transport code (MCNP-4A) to estimate the level at which the scattered photon fluence rate, the absolute efficiency of the HPGe-detector, the volume of the concrete sample and the $^{35}$ /Cl(n, ${\gamma}$) reaction rate in this sample contribute to the count rate in the NaCl concentration measurement. The n- ${\gamma}$ fluence rates at the ST-2 beam tube exit of the HANARO reactor were used as input data, and the GAMMA-X type HPGe detector was modeled to tally 1.1649 MeV ${\gamma}$ -rays emitted from the $^{35}$ Cl(n, ${\gamma}$) reaction in the concrete sample. For three cylindrical concrete samples of 13.8, 46.8 and 157.1 ㎤ volumes, respectively, the relations between the NaCl weight fractions of 0.1, 1, 2 and 5 % in each of the concrete samples and the 1.1 649 MeV pulses created in the HPGe detector model were studied. As a result, it was found that the count rate at the same NaCl concentration nearly depends on the volume of the samples in a simulated condition of the same NaCl concentration samples, and that the linearities of the NaCl concentration calibration curves were reasonable in the narrow range of the NaCl weight fraction.

• The Journal of Internal Korean Medicine
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• v.32 no.1
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• pp.1-9
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• 2011

Objectives : This study was performed in order to investigate the effect of Panax notoginseng(SCG) on phenylhydrazine (PHZ)-induced hemolytic anemia in rats. Materials and Methods : Rats were divided equally into 3 groups (Normal, Control, SCG). Anemic model rats (Control, SCG) were induced by the treatment of PHZ (40mg/kg/day, i.p.) for 3 days. Red blood cell, hemoglobin, reticulocyte count, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration were determined on days 0, 4, 7 and 10. Body weight was investigated on days 0, 2, 4, 6, 8, 10 and weight of spleen was measured on day 10. Results : In the SCG group, significantly higher levels of RBC was found on day 4 and higher concentration of Hb on days 4, 7 and 10. Furthermore, reticulocyte count was dramatically lower on day 10 compared to the control group. Conclusions : These results suggest that SCG may be beneficial in the treatment of hemolytic anemia.

• Journal of Microbiology and Biotechnology
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• v.15 no.6
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• pp.1353-1358
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• 2005

A rapid and quantitative real-time PCR was developed to target the invasion A (invA) gene of Salmonella spp. We developed quantitative standard curves based on plasmids containing the invA gene. Based on these curves, we detected Salmonella spp. in artificially contaminated buffered peptone water (BPW) and milk samples. We were able to determine the invA gene copy number per ml of food samples, with the minimum detection limit of $4.1{\times}10^{3}$ copies/ml of BPW and $3.3{\times}10^{3}$ copies/ml of milk. When applied directly to detect and quantify Salmonella spp. in BPW and milk, the present real-time PCR assay was as sensitive as the plate count method; however, copy numbers were one to two logs higher than the colony-forming units obtained by the plate count methods. In the present work, the real-time PCR assay was shown to significantly reduce the total time necessary for the detection of Salmonella spp. in foods and to provide an important model for other foodborne pathogens.

• Environmental Engineering Research
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• v.21 no.4
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• pp.365-372
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• 2016

The effects of hydrodynamics and alum dose on particle growth were investigated by monitoring particle counts in a rapid mixing process. Experiments were performed to measure the particle growth and breakup under various conditions. The rapid mixing scheme consisted of the following operating parameters: Velocity gradient (G) ($200-300s^{-1}$), alum dose (10-50 mg/L) and mixing time (30-180 s). The Poisson regression model was applied to assess the effects of the doses and velocity gradient with mixing time. The mechanism for the growth and breakup of particles was elucidated. An increase in alum dose was found to accelerate the particle count reduction. The particle count at a G value of $200s^{-1}$ decreased more rapidly than those at $300s^{-1}$. The growth and breakup of larger particles were more clearly observed at higher alum doses. Variations of particles due to aggregation and breakup of micro-flocs in rapid mixing step were interactively affected by G, mixing time and alum dose. Micro-flocculation played an important role in a rapid mixing process.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.8
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• pp.1039-1046
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• 2004

A model Indigenous Thai beef cattle breeding structure consisting of nucleus, multiplier and commercial units was used to evaluate the effect of changes in heritabilities of and genetic correlations between adaptation traits on genetic gain and profitability. A breeding objective that incorporated adaptation was considered. Two scenarios for improving both the production and the adaptation of animals where also compared in terms of their genetic and economic efficiency. A base scenario was modelled where selection is for production traits and adaptation is assumed to be under the forces of natural selection. The second scenario (+Adaptation) included all the information available for base scenario with the addition of indirect measures of adaptation. These measures included tick count (TICK), faecal egg count (FEC) and rectal temperature (RECT). Therefore, the main difference between these scenarios was seen in the records available for use as selection criteria and hence the level of investments. Additional genetic gain and profitability was generated through incorporating indirect measures of adaptation as criteria measured in the breeding program. Unsurprisingly, the results were sensitive to the changes in heritabilities and genetic correlations between adaptation traits. However, there were more changes in the genetic gain and profitability of the breeding program when the genetic correlations of adaptation and its indirect measures were varied than when the correlations between these measures were. The changes in the magnitudes of the genetic gain and profit per cow stresses the importance of using reliable estimates of these traits in any breeding program.

• The Korean Journal of Applied Statistics
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• v.27 no.3
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• pp.445-459
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• 2014

As a certain job is repeatedly done by a worker, the outcome comparative to the effort to complete the job gets more remarkable. The outcome may be the time required and fraction defective. This phenomenon is referred to a learning-curve effect. We focus on the parametric modeling of the learning-curve effects on count data using a logistic cumulative distribution function and some probability mass functions such as a Poisson and negative binomial. We conduct various simulation scenarios to clarify the characteristics of the proposed model. We also consider a real application to compare the two discrete-type distribution functions.

• The Korean Journal of Health Service Management
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• v.14 no.1
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• pp.161-176
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• 2020

Objectives: The purpose of this study was to investigate the effects of health status and health behaviors on health-related quality of life in Korean adults. Methods: The study was based on the 2017 National Health and Nutrition Survey. Of the total 8,127 people, 5,780 (71.1%) participated: 2,553 (44.2%) were male and 3,227 (55.8%) were female. The variables for this study were demographic factors, disease count, subjective health status, health behaviors, and health-related quality of life (measured by the EQ-5D Index). Results: After analysis, the statistically significant factors associated with health-related quality of life were gender, age, income, education, daytime health status, number of comorbidities (6 or more) and stress. Conclusions: Seven demographic factors have been identified as having a significant impact on health-related quality of life, categorized by model, gender, age and income. Therefore, it is possible that quality of life can be improved through proactive management and by improving subjective health status and health behaviors while in considering of demographic and sociological factors by providing indicators as per gender and age.