• Journal of Nutrition and Health
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• v.38 no.7
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• pp.521-532
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• 2005

The prevalence of atopic dermatitis (AD) continues to rise in industrialized countries related to Western lifestyle, including dietary habits, especially imbalance of intake of dietary fatty acids. The purpose of this study was to evaluate the dietary fatty acids and the assess the blood fatty acid composition and immune parameters in AD patients. AD (n = 50) patients and gender ${\cdot}$ age matched healthy controls (HC) were studied in case-control clinical trail. Current fatty acids intake status was determined by 3-day food record method. Blood sample were collected from 30 subjects in each group and blood fatty acid composition and immune parameters were analysed. AD patients consumed less PUFA and their n-6/n-3 PUFA ratio was higher than that of HC. Both the ratios of PUFA and MUFA were positively correlated with SCORAD in AD patients (p < 0.05). In the AD patients, there were abnormalities in the fatty acid composition of the RBC and WBC, SFA being significantly high and most n-3 PUFA being significantly low. Moreover, both the ratios of EPA and DHA in WBC were negatively correlated with dietary n-6/n-3 PUFA ratio in AD patients (p < 0.05). Serum total IgE and IL-4 levels of AD patients increased significantly compared with the levels of HC (p < 0.01). Ratios of monocyte and eosinophil in WBC of AD patients increased significantly compared with the levels of HC including total WBC count (p < 0.01), and ratios of Iymphocyte and basophil in WBC of AD patients decreased significantly compared with the levels of HC (p < 0.05). Moreover, the ratios of eosinophil in WBC were positively correlated with dietary P/M ratio (p < 0.05), and the ratios of monocyte in WBC were positively correlated with n-6/n-3 PUFA ratio (p < 0.05) in AD patients. This results indicated that AD patients had significantly high intake of dietary n-6/n-3 PUFA compared with HC. Imbalance of intake of dietary fatty acids affected fatty acid compositions in the RBC and WBC, and these lead to immune imbalance and grow worse of AD.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.33-33
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• 2013

We are developing empirical space weather (solar flare, solar proton event, and geomagnetic storm) forecast models based on solar data. In this talk we will review our main results and recent progress. First, we have examined solar flare (R) occurrence probability depending on sunspot McIntosh classification, its area, and its area change. We find that sunspot area and its increase (a proxy of flux emergence) greatly enhance solar flare occurrence rates for several sunspot classes. Second, a solar proton event (S) forecast model depending on flare parameters (flare strength, duration, and longitude) as well as CME parameters (speed and angular width) has been developed. We find that solar proton event probability strongly depends on these parameters and CME speed is well correlated with solar proton flux for disk events. Third, we have developed an empirical storm (G) forecast model to predict probability and strength of a storm using halo CME - Dst storm data. For this we use storm probability maps depending on CME parameters such as speed, location, and earthward direction. We are also looking for geoeffective CME parameters such as cone model parameters and magnetic field orientation. We find that all superstorms (less than -200 nT) occurred in the western hemisphere with southward field orientations. We have a plan to set up a storm forecast method with a three-stage approach, which will make a prediction within four hours after the solar coronagraph data become available. We expect that this study will enable us to forecast the onset and strength of a geomagnetic storm a few days in advance using only CME parameters and the WSA-ENLIL model. Finally, we discuss several ongoing works for space weather applications.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.10 no.1
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• pp.54-61
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• 2011

Ball screw systems are largely used in industry for motion control and motor applications. But the problem of noise, which really perplexes us, is highly correlated with the quality in ball screw systems all the way. In this paper, machining process parameters were evaluated in respects of technique, business, produce and quality to verify which impact influences the noise most. In order to adjust and compare, two comparison groups were set with the present parameters bench mark. Different ball screws were produced as specimens for the noise tests. Through comparing the noise performance of different parameters in the machining process respectively, a group of optimized machining process parameters were obtained. Another noise test was proceeded to know how noise performance was improved by optimizing the machining process parameters. At last, surface roughness tests have been done to know how surface roughness improved by optimization. The improvement of surface roughness is the main factor influences the noise performances.

• Textile Coloration and Finishing
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• v.31 no.4
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• pp.298-311
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• 2019

In this study, the mechanical properties and hand characteristics of the knitted and woven fabrics for bedding items are investigated in accordance with fabric structural parameters including the fiber type and proportion, the density of the fabric, and the knit/weave structure. The knit stitches and structure of the knit samples made an effect on tensile properties. The bending, shear and compression properties for the knit fabric were mainly affected by fiber contents of the samples. The tensile and bending properties of woven samples were highly correlated with the fabric density, thickness and structure, and those shear and compression properties were affected by the fiber contents and structure. Consequently, the primary hand values of the selected samples we developed were estimated to have good smoothness, fullness and softness, and soft feeling, which is well correlated to the parameters of consumer preference such as softness, warmness, and bulkiness. Also, their total hand values were increased.

• Environmental Engineering Research
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• v.20 no.3
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• pp.254-259
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• 2015

In this study, the characteristics as well as the maturity and stability of chicken manure collected from nine chicken farms in South Korea during the summer and winter seasons of 2014 are evaluated. The physicochemical parameter values of the manure, such as BOD, $NO_3-N$ and $PO_4-P$ etc. were determined using the Korea Standard test Method, HPLC, and APHA standard methods. The results showed that the alkalinity content and COD concentration in winter chicken manure were higher than those of summer chicken manure. The moisture content of summer manure was positively correlated with almost all of the other parameters of the manure, whereas it was negatively correlated with almost all of the other parameters in the winter manure. According to the criterion of C/N ratio, chicken manure indicated good quality compost. However, composted chicken manure showed immature and unstable compost when considering the criteria of the $NH_4-N/NO_3-N$ ratio and $NH_4-N$ concentrations.

• YAKHAK HOEJI
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• v.46 no.1
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• pp.63-68
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• 2002

The purpose of this study was to estimate the population pharmacokinetics of clarithromycin in healthy adult Korean and to investigate the factors influencing the pharmacokinetics of clarithromycin. The population pharmacokinetic parameters of clarithromycin were calculated with the data from healthy adult Koreans. A total of 798 plasma concentrations obtained from 78 subjects after administration of a single oral dose of 250 mg or 500 mg were used for the modeling. The concentration-time data were fitted to a one-compartment open model assuming a first-order absorption and elimination with no lag time. The correlations between various factors [such as sex, age, height, weight, sect creatinine (Scr) and dose and pharmacokinetic parameters were estimated with stepwise linear recession analyses. The selected covariates were incorporated in the population model of NONMEM, and the importance of each covariate was investigated by means of backwards elimination. The apparent clearance (CL/F) was significantly correlated to Scr and sex, and the apparent volume of distribution (Vd/F) was significantly correlated to Scr and height in a nonlinear relationship. The population values of Ka was 1.8 h $r_{-1}$, CL/F was 37.71 L/hr, Vd/F was 200 L and t/ sub 1/2 / was 3.68 hrs for a male Korean with 170 m height and 1.0 mg/dL Scr.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.7
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• pp.984-989
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• 2004

Three hundred and twelve female Tsaiya ducks from four lines (L1051, L1052, L1053 and L1054) were used in this study to investigate the changes in plasma calcium and inorganic phosphorus levels, blood pH, carbon dioxide partial pressure (pCO$_{2}$), bicarbonate ion concentration ($HCO_{3}^{-}$), and base excess (BE) during laying periods. The results indicated that plasma calcium and inorganic phosphorus concentration at 40 and 50 wks of age were higher (p<0.05) than those at other ages. Significant positive correlation coefficients were found between plasma calcium and inorganic phosphorus levels at each age tested from 20 to 50 wks. Ducks from L1053 showed lower (p<0.05) blood pH, BE and $HCO_{3}^{-}$ as compared with other lines. Ducks from L1054 had higher (p<0.05) blood pH, BE and $HCO_{3}^{-}$ than those of other lines showing that there were some differences on blood parameters among lines. Eggshell strength decreased with age up to 65 wks and remained constant thereafter. Egg weight increased gradually from 30 to 60 wks and decreased slightly after 70 wks of age. Plasma inorganic phosphorus level in 40 and 50 wks old birds was positively correlated with eggshell strength, while blood $HCO_{3}^{-}$ in 40 and 50 wks old birds was negatively correlated with eggshell strength.

• Earthquakes and Structures
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• v.21 no.6
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• pp.563-576
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• 2021

The rocking foundation is effective for reducing structural seismic demand and avoiding overdesign of the foundation. It is crucial to evaluate the performance of rocking foundations because they cause plastic hinging in the soil. In this study, to derive optimized ground motion intensity measures (IMs) for rocking foundations, the efficiency of IMs correlated with engineering demand parameters (EDPs) was estimated through the coefficient determination using a physical modeling database for rocking shallow foundations. Foundation deformations, the structural horizontal drift ratio, and contribution in drift from foundation rotation and sliding were selected as crucial EDPs for the evaluation of rocking foundation systems. Among 15 different IMs, the peak ground velocity exhibited the most efficient parameters correlated with the EDPs, and it was discovered to be an efficient ground motion IM for predicting the seismic performance of rocking foundations. For vector regression, which uses two IMs to present the EDPs, the IMs indicating time features improved the efficiency of the regression curves, but the correlation was poor when these are used independently. Moreover, the ratio of the column-hinging base shear coefficient to the rocking base shear coefficient showed obvious trends for the accurate assessment of the seismic performance of rocking foundation-structure systems.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.6
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• pp.842-850
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• 2018

Objective: Several studies have reported the development of new molecular methods for the prognosis and diagnosis of male fertility based on biomarkers aimed at overcoming the limitations of conventional male fertility analysis tools. However, further studies are needed for the field application of these methods. Therefore, alternative methods based on existing semen analysis methods are required to improve production efficiency in the animal industry. Methods: we examined the possibility of improving litter size in various pig breeds using combined Hoechst 33258/chlortetracycline fluorescence (H33258/CTC) staining. The correlation between field fertility and capacitation status by combined H33258/CTC staining in different ejaculates spermatozoa (n = 3) from an individual boar (20 Landrace, 20 Yorkshire, and 20 Duroc) was evaluated as well as overall accuracy. Results: The acrosome reacted (AR) pattern after capacitation (%) was positively correlated with the litter size of Landrace, Yorkshire, and Duroc pigs and the overall accuracy was 75%, 75%, and 70% in Landrace, Yorkshire, and Duroc pigs, respectively. The difference (${\Delta}$) in AR pattern before and after capacitation was positively correlated with the litter size of Landrace, Yorkshire, and Duroc pigs and the overall accuracy was 80%, 65%, and 55% in Landrace, Yorkshire, and Duroc pigs, respectively. However, the difference (${\Delta}$) in capacitated (B) pattern before and after capacitation was negatively correlated with the litter size of Landrace pigs and the overall accuracy was 75%. Moreover, average litter size was significantly altered according to different combined H33258/CTC staining parameters. Conclusion: These results show that combined H33258/CTC staining may be used to predict male fertility in various breeds. However, the selection of specific efficiency combined H33258/CTC staining parameters requires further consideration. Taken together, these findings suggest that combined H33258/CTC staining may constitute an alternative method for predicting male fertility until such time as fertility-related biomarkers are further validated.

• Reproductive and Developmental Biology
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• v.31 no.2
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• pp.121-126
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• 2007

The objective of this study was to establish the optimal conditions for hypoosmotic swelling (HOS) test to assess the functional integrity of the membranes of boar fresh or frozen/thawed spermatozoa. When pooled semen sample was incubated for 30 min at $37^{\circ}C$ with different test solution of varied osmolarity, the highest percentage of HOS positive spermatozoa was observed in a 150 mOsmol fructose/Na-citrate solution (33.6%). Incubation time did not affect significantly the score of HOS positive spermatozoa observed in a 150 mOsmol fructose/Na-citrate solution at $37^{\circ}C$, but the osmolarity affected the score of HOS positive spermatozoa under the same condition above. Fresh semen was significantly better than frozen/thawed semen in semen parameters evaluated such as motility, viability, membrane integrity and lipid peroxidation (p<005). In the relationships of sperm parameters, motility vs viability, motility vs membrane integrity and viability vs membrane integrity were positively correlated ($0.82{\sim}0.94$) but lipid peroxidation vs other estimated factors was negatively correlated ($- 0.90{\sim}- 0.98$). Among the evaluation methods, motility vs Viability, motility vs membrane integrity and lipid peroxidation vs other estimated factors were significantly correlated (p<0.05). These results of this. study indicate that the optimal condition of HOST in boar spermatozoa is a 150 mOsmol fructose/Na-citrate solution for 30 min incubation at $37^{\circ}C$ and HOST can substitute the examination of motility, viability and lipid peroxidation.