• Korean Journal of Fisheries and Aquatic Sciences
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• v.48 no.1
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• pp.1-15
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• 2015

Tissue engineering is an emerging, innovative technology to improve or replace the biological functions of damaged tissues and organs. Scaffolds are important materials for tissue engineering as they support cell attachment, migration, and differentiation. Marine sponges naturally contain scaffolds formed by extracellular matrix proteins (collagen and sponging) and strengthened by a siliceous or calcium carbonate skeleton. Coral skeletons are also derived naturally formed by essential calcium carbonate in the form of aragonite, and are similar to human bone. In addition, collagen extracted from jellyfish is a biosafe alternative to bovine and porcine collagen and gained attention as a potential source for tissue engineering. Moreover, cuttlefish bone is an excellent calcium source and can be used to generate bio-synthetic calcium phosphate. It has become a natural candidate for biomimetic scaffolds. This review describes the use of natural products derived from marine invertebrates for applications in bone tissue engineering based on studies from 2008 to 2014.

• Natural Product Sciences
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• v.18 no.2
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• pp.102-105
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• 2012

Marine organism extracts were prepared from 26 species of Korean indigenous marine organisms, including 25 species belonging in class Anthozoa of phylum Cnidaria and a species belonging to subphylum Urochordata of phylum Chordata, and screened their inhibitory effects against ${\mu}$-calpain. As a result, the thirteen extracts were found to be active in the criteria of $IC_{50}$ < 100 ${\mu}g/ml$. Among them, the MeOH extracts of Plexauroides praelonga and Alveopora japonica showed remarkable ${\mu}$-calpain inhibitory activity with $IC_{50}$ values of $4.62{\pm}0.22$ and $4.82{\pm}0.07{\mu}g/ml$, respectively. In addition, chemical investigation of A. japonica led to the isolation of an active compound, hexadecyl tetradecanoate, as a selective cathepsin B inhibitor ($IC_{50}=9.05{\pm}2.45{\mu}M$). This compound was isolated as constituent of A. japonica for the first time in the present study.

• YAKHAK HOEJI
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• v.41 no.5
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• pp.547-553
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• 1997

The purpose of this investigation was to determine the inhibition on $Na^+,\;K^+$-ATPase, cyclic AMP phosphodiesterase and platelet activation by marine sterols isolated from octocorals. Three marine polyhydroxysterols, 7${\alpha},\;8{\alpha}-epoxy-3b{\beta},\;5{\alpha},\;6{\alpha}-trihydroxycholestane (1),\;24-methyl-7{\alpha},\;8{\alpha}-epoxy-3{\beta},\;5{\alpha},\;6{\alpha}-trihydroxycholest-22-ene (2),\;and\;7{\alpha},\;8{\alpha}-epoxy-3{\beta},\;5{\alpha},\;6{\alpha}-trihydroxycholest-22-ene (3)$, were isolated from the Gorgonian Acabaria undulata. Five marine sterols(compound 4, 5, 6, 7, 8) were isolated from the soft coral Alcyonium gracillimum. Three marine polyhydroxysterols (1, 2, 3) and pregna-1. 20-diene-3-one (8) exhibit a potent inhibitory effect on rabbit platelet aggregation induced by collagen and thrombin. Those polyhydroxysterols also exhibit a potent inhibitory effect on cyclic AMP phosphodiesterase. Compound 6 with an unusual cyclic enolether exhibit a inhibitory effect on $Na^+,\;K^+$-ATPase.

• Journal of the Korean GEO-environmental Society
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• v.13 no.4
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• pp.71-76
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• 2012

Shear strength of soil is power that resists failure and sliding according to any face in soils and one of the most important factors during engineering properties of soil. Shear strength is used for engineering science problems as bearing capacity methods of foundation or piles, slope stability after dam or Cutting Embankment and stability problem analysis of soils as lateral earth pressure of soil structures, ets. This study has analyzed shear strength change of samples classified 2.00mm(10sieve)와 0.85mm(20sieve), 0.475mm(40sieve) using direct shear tester after removing and drying cohesive soil ingredient of Weathered granite soil Therefore, this study would help studies about shear strength properties by particle size.

• Journal of Fisheries and Marine Sciences Education
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• v.29 no.2
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• pp.396-408
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• 2017

This study aims to analyze pre-service elementary teachers' oceanographic literacy, understanding of ocean environmental problems and opinions on teaching strategies for ocean topics. As survey participants, this study selected 126 pre-service elementary teachers. Firstly, as a result of testing their oceanographic literacy, this study found out that out of all the basic principles, 'Oceans Largely Unexplored' was highest in the mean score, followed by 'Human Connections', 'Ocean & Its Life Shape Earth', 'Habitability', 'Biodiversity', 'Weather & Climate' and 'Size of Ocean'. Besides, regarding environmental problems affecting all the aspects of ocean, they mentioned oil spills caused by vessel accidents, so called 'Oil Pollution', as the most serious marine environmental problem. Regarding environmental problems affecting coral reefs, they considered over-fishing as the most serious problem. Secondly, as a result of analyzing their opinions on effective teaching strategies for ocean-related topics in elementary science textbooks, this study found out that regarding topics about understanding the undersea topography in the chapter of the earth and moon, they proposed 'Making an Undersea Topographic Model with Sand' most as an effective teaching strategy. As an effective teaching strategy for the chapter of animals' lives, they proposed 'Classifying Animals with Marine Animal Cards' most. As an effective teaching strategy for the chapter of ground surface changes, they proposed 'Making and Simulating Seashore Topography' most.

• Natural Product Sciences
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• v.27 no.2
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• pp.61-67
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• 2021

Since ancient times, various herbal medicines have been used in folk medicine to treat a variety of diseases. While the majority of drugs belong to the Kingdom of Plantae, some drugs from the Kingdom of Animalia are listed in various Materia medica of alternative medicines. Animal-derived drugs are mentioned in the Unani system of Medicine (USM) and have been used successfully to treat a variety of diseases. Marjān (Corallium rubrum) is a vital marine drug of animal origin that has been used in USM since ancient times and continues to be used today. It possesses a variety of beneficial pharmacological properties, including tonic effects on the heart, brain, stomach, and eyes, pregnancy protection, expectorant, and hemostyptic properties. It is used to treat hemoptysis, palpitation, bleeding piles, hemiplegia, heart failure, and general weakness. It is also an ingredient in a variety of Unani formulations with pharmacological significance. Unani physicians expanded the uses of Marjan and successfully used it to treat a variety of new diseases. There is a dearth of scientific research on its pharmacological and medicinal properties. The urgent need is to validate the Unani claims about its beneficial cardiac and nervine actions, as well as other significant actions mentioned in the Unani literature.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• fall
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• pp.304-307
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• 2021

ML(machine learning) 기술을 활용하여 실용적인 측면에서 일반 사용자들이 바라보고 사용할 수 있도록 다양한 연구 개발이 이루어지고 있다. 특히 최근 개인 사용자의 personal computer와 mobile device의 processing unit의 연산 처리 속도가 두드러지게 빨라지고 있어 ML이 더 생활에 밀접해지고 있는 추세라고 볼 수 있다. 현재 ML시장에서 다양한 솔루션 및 어플리케이션을 제공하는 툴이나 라이브러리가 대거 공개되고 있는데 그 중에서도 Google에서 개발하여 배포한 'Mediapipe'를 사용하였다. Mediapipe는 현재 'android', 'IOS', 'C++', 'Python', 'JS', 'Coral' 등의 환경에서 개발을 지원하고 있으며 더욱 다양한 환경을 지원할 예정이다. 이에 본 팀은 앞서 설명한 Mediapipe 프레임워크를 기반으로 Machine Learning을 사용한 image processing를 통해 일반 사용자들에게 편의성을 제공할 수 있는 알람 프로그램을 연구 및 개발하였다. Mediapipe에서 신체를 landmark로 검출하게 되는데 이를 scikit-learn 머신러닝 라이브러리를 사용하여 특정 자세를 학습시키고 모델화하여 알람 프로그램에 특정 기능에 조건으로 사용될 수 있게 하였다. scikit-learn은 아나콘다 등과 같은 개발환경 패키지에서 간단하게 이용 가능한데 이 아나콘다는 데이터 분석이나 그래프 그리기 등, 파이썬에 자주 사용되는 라이브러리를 포함한 개발환경이라고 할 수 있다. 하여 본 팀은 ML기반의 영상처리 알람 프로그램을 제작하는데에 있어 이러한 사항들을 파이썬 환경에서 기본적으로 포함되어 제공하는 tkinter GUI툴을 사용하고 추가적으로 인텔에서 개발한 실시간 컴퓨터 비전을 목적으로 한 프로그래밍 라이브러리 OpenCV와 여러 항목을 사용하여 환경을 구축할 수 있도록 연구·개발하였다.

• Korean Journal of Environmental Biology
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• v.41 no.4
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• pp.570-607
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• 2023

The subgenus Tricoma Cobb, 1894 comprises free-living marine nematodes encompassing a total of 83 validated taxa. Within this diversity, twenty-one taxa thrive in the deep sea, while twenty-three are found in coral reefs, flat areas, or green algae. Additionally, eleven taxa inhabit the sublittoral zone at depths exceeding 10 meters, and the remaining taxa are situated on beaches, coasts, or in habitats lacking detailed information. In the course of a survey focused on the East Sea free-living marine nematodes, we identified four new and two previously unrecorded species belonging to the subgenus Tricoma. Specifically, two new species, Tricoma (Tricoma) breviseta sp. nov. and T. (T.) donghaensis sp. nov., were discovered in mud-sandy sediment in deepsea environments below 2000 meters within the Ulleung Basin and Hupo Bank. Two previously unrecorded species [T. (T.) paralucida Decraemer, 1987 and T. (T.) similis Cobb, 1912] and the two newly found species [T. (T.) longicauda sp. nov. and T. (T.) ulleungensis sp. nov.] were obtained from subtidal coarse sand at a depth of 20 meters during a survey of the waters surrounding Ulleungdo Island. The distribution and information on validated taxa within the subgenus Tricoma were systematically collected, reviewed, and cataloged. Detailed morphological features and illustrations of Tricoma species from Korea were provided through the use of differential interference contrast microscopy.

• ALGAE
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• v.39 no.3
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• pp.163-176
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• 2024

Some marine microalgae and cyanobacteria form mutualistic symbioses with diverse invertebrates, particularly cnidarians. Among microalgae, dinoflagellates in the family Symbiodiniaceae are the most well-known symbiotic partners of jellyfish and corals. However, the symbioses involving other dinoflagellate families, nano- and micro-flagellates, diatoms, and cyanobacteria with cnidarians are not well understood. As an initial step, it is essential to explore the survival of these microorganisms inside cnidarians. We monitored the survival of eight microalgal species (nine strains) and one cyanobacterium species every day for seven days after injecting each into the medusa of the moon jellyfish Aurelia aurita. The dinoflagellates Effrenium voratum (free-living [FL] and living-in-coral strains), Cladocopium infistulum, Prorocentrum cordatum, Prorocentrum koreanum, Symbiodinium microadriaticum, the prasinophyte Tetraselmis suecica, the chlorophyte Dunaliella salina, and the raphidophyte Heterosigma akashiwo survived inside the medusa, while the cyanobacterium Synechococcus sp. was not detected. Additionally, E. voratum (FL) survived within the medusa for 60 days and gradually spread to adjacent areas, indicating potential for artificially established symbiosis. The results of this study provide a basis for artificial symbiosis between microalgae and invertebrates.

• Journal of Agricultural Extension & Community Development
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• v.1 no.2
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• pp.147-163
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• 1994

Agricultural extension programs in Korea had focused mainly on increased production, and the biggest pride of extension was the achievement of rice self-sufficency in 1970s and abundant vegetable and animal production in 1980s. Farming in Korea has changed rapidly in recent years and extension system on commercialized crops have not been satisfactorily developed to mete farmers` demands. Facing the emerging challenges of international competition and trade liberalization for agricultural commodities, the goals of extension should be focused on increased income and the welfare of coral communities. The transfering of agricultural extension educator from central government jobs to local ones has emerged recently under the trends of localization which resulted unstable job environment of extension educator. Intensive pre-service and in-service training of extension workers on current and advanced techologies are essential to upgrade the quality of extension services, and the future directions for professional development of agricultural extension educators in Korea were suggested as follows: 1. Establishing a national network on agricultural extension system to promote exchanges of information among counties and provinces, to conduct meetings and to publish information on agricultural extension. 2. Determining the implications of recent national and global trends on agricultural extension, and strenthening communication at local, national and international levels for an effective extension system in the era of localization, internationalization and globalization; 3. Recognizing the effect of number and quality of extension staff on the impact of extension and providing opportunities development and advancement of extension personnel through education, training, incentives and rewards; 4. Giving a higher priority to agricultural extension in national policies in order to ensure the adequacy of budgetary support and recognition of importance of extension by the ministries concerned and mass communications.