• 제목/요약/키워드: contractility

검색결과 320건 처리시간 0.023초

Sonographic evaluation of the diaphragm in patients with unilateral diaphragmatic paralysis

  • Seok, Jung Im;Kim, Kyung Chan;Rha, Hye Joo;Lee, Sung Rok
    • Annals of Clinical Neurophysiology
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    • 제20권2호
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    • pp.93-96
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    • 2018
  • Evaluation of diaphragm function is challenging because no single test has a high diagnostic yield. We describe ultrasound findings in three cases with acquired unilateral diaphragmatic elevation. These cases confirm that sonographic evaluation is a valid tool for identifying diaphragm dysfunction. In addition, ultrasound measurements of diaphragm thickness and the contractility can be used to determine if a diaphragm is paralyzed and suggest the duration of paralysis (i.e., acute or chronic).

월경곤란증에서의 성상신경절 차단 효과 -증례 보고- (Stellate Ganglion Block for the Treatment of Primary Dysmenorrhea -Two cases-)

  • 임현경;정종권;김태정
    • The Korean Journal of Pain
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    • 제11권1호
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    • pp.113-115
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    • 1998
  • Dysmenorrhea(cyclic pain associated with menses) is a frequent disorder, with as many as 50% of young women experiencing the symptom, and up to 10% being unable to function normally for some time each month. The most recent theory of the cause of the pain of dysmenorrhea incriminates uterine ischemia and sensitization of uterine pain fibers resulting from excessive myometrial contractility after prostaglandin stimulation. We administered stellate ganglion block for the treatment of dysmenorrhea and had good results in two cases. From our experience, we recommend the stellate ganglion block may be an effective treatment for a dysmenorrhea.

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승모판막질환을 동반하지 않은 심방세동에서의 Cox-Maze 술식 -3례 보고- (The Cox-Maze Procedure for Atrial Fibrillation not Associated with Mitral Valve Disease -Report of three cases-)

  • 강창현;김기봉
    • Journal of Chest Surgery
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    • 제31권12호
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    • pp.1230-1233
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    • 1998
  • The Cox-Maze procedure was developed as a cure for atrial fibrillation. The recovery rate of both atrial contractility is reported low in the atrial fibrillation associated with mitral valvular heart disease than that of loan atrial fibrillation. We performed the Cox-Maze procedure (Maze III) in three cases who suffered from non-mitral heart diseases associated with atrial fibrillation: A ruptured sinus of Valsalva aneurysm, a ventricular septal defect, and an aortic stenoinsufficiency. The Cox-Maze procedure was performed concomitantly with correction of the underlying heart disease. Conversion to sinus rhythm was achieved in all three patients, and both right and left atrial mechanical activities could be identified echocardiographically after three postoperative months.

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흰쥐의 허혈심장에서의 Adenosine의 심근 보호 효과에 관한 연구 (Myocardial Protective Effect of Adenosine in Ischemic Rat Heart)

  • 박승규
    • Journal of Chest Surgery
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    • 제23권6호
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    • pp.1090-1106
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    • 1990
  • This study was undertaken to investigate whether adenosine administered during cardioplegic arrest could enhance myocardial protection and improve recovery of function after ischemia. Isolated Langendorff-perfused rat hearts were subjected to 40 minutes of normothermic [37oC] ischemia. Control hearts [n=10] received modified St. Thomas’ cardioplegic solution, and the remaining hearts received modified St. Thomas’ cardioplegic solution with either 20 \ulcornerM [n=10], 200 \ulcornerM [n=10] adenosine. After ischemia of 40 minutes and 30 minutes of reperfusion, left ventricular contractility was superior in all groups of adenosine-treated hearts compared with control hearts. Furthermore, there was a significant incremental increase in functional recovery with increasing dose of adenosine. Post-ischemic diastolic stiffness was significantly better in all adenosine groups compared with controls. No differences were noted in coronary flow or myocardial water content between adenosine-treated and control hearts. These data demonstrate that adenosine administered in these concentrations provides myocardial protection, preservation of myocardial ATP and creatine phosphokinase and improved post-ischemic functional hemodynamic recovery after normothermic ischemia, presumably metabolically by reducing depletion of adenosine triphosphate, inducing rapid cardiac arrest and enabling improved post-ischemic recovery.

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신생 돼지심장에서 상온의 Krebs 용액 관류에 따른 좌심실 기능의 변화 (Left Ventricular Function Changes Under Normothermic Krebs Perfusate in Newborn Piglet)

  • 오봉석;나국주;이동준
    • Journal of Chest Surgery
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    • 제23권6호
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    • pp.1067-1073
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    • 1990
  • To clarify the changes of left ventricular function under normothermia, the time interval between the onset of ischemia and the beginning of contracture of left ventricle[TIC] were recorded in newborn piglet. Myocardial performance was assessed using intraventricular balloon to determine compliance and systolic function after 5 to 10 minutes interval per-fusing normothermic substrate free Krebs solution as a perfusate. The time to onset TIC was 29.5\ulcorner1.7 minutes and peak ischemic contracture was 46.7\ulcorner4.0 minutes[p<0.01]. In myocardial performance, systolic function of left ventricle[defined as cardiac contractility] was kept until 25 minutes of perfusion, but was decreased abruptly after 30 minutes of perfusion[p<0.0018] and diastolic function of left ventricle[defined as diastolic compliance] was kept until 15 minutes of perfusion, but was decreased after 20 minutes of perfusion [p=0.00\ulcorner9]. This study demonstrated maximal time of the tolerance to normothermic global ischemia and functional changes of left ventricle using Krebs perfusate under the same condition.

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체외순환이 갑상선호르몬 농도에 미치는 영향에 관한 연구 (The effect of cardiopumonary bypass on the concentrations of thyroid hormone)

  • 김규만;전상협;김종원
    • Journal of Chest Surgery
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    • 제27권7호
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    • pp.571-575
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    • 1994
  • The hemodynamic effects of thyroid hormone are well established, and this hormone affects myocardial contractility, heart rate, and myocardial oxygen consumption. But the role of cardiopulmonary bypass on the thyroid function is not yet fully understood. We have studied twelve patients [male and female patients were equal in number] who were performed open heart surgery under cardiopulmonary bypass. The results are followed. 1] The serum level of T3 began to fall after cardiopulmonary bypass and sustained significantly till 24 hours after operation[p<0.05] 2] The concentrations of T4, Free T4, and TSH were slightly decreased after cardiopulmonary bypass but was maintained within normal range. 3] This above findings are similar to the "sick sinus syndrome" that is seen in severely ill patient. 4] We can propose that T3 would be effective in postoperative low cardiac output syndrome. syndrome.

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한국산산형과식물의 성분연구 IX Isoimperatorin 및 Oxypeucedanin의 일선약리작용 (Studies on the Components of Umbelliferous Plants in Korea(IX) Pharmacological Study of Isoimperatorin and Oxypeucedanin)

  • 지형준;김학성
    • 약학회지
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    • 제14권1_2호
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    • pp.21-27
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    • 1970
  • Isoimperatorin and Oxypeucedanin isolated from root of Angelica Koreana Max. (Umbelliferae) that is used as "Kang-Whal" a botanical drug, in Korea, Show following general pharmacologic activities. The treatment with Oxypeucedanin on the exercised duodenum of the rabbit increased the motility of it while isoimperatorin shows little effects. But on the exercised heart of the frogs, both components depressed its contractility. Whereas Oxypeucedanin depressed both blood pressure of the carotied artery and respiration of the rabbit, Isoimperatorin tends to increase blood pressure, respiration and the tonus of the muscle of the earth worm. Oxypeucedanin did not affect the tonus of the muscles of the earth worm, but depressed the uterus contraction of the rabbit, which was, on the contrary, increased by Isoimperatorin.

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심장운동부하 모델링과 의료장비 개발 (Modeling for the Work of Heart and Development of the WOH Medical device)

  • 노형운;서상호
    • 유체기계공업학회:학술대회논문집
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    • 유체기계공업학회 2006년 제4회 한국유체공학학술대회 논문집
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    • pp.501-504
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    • 2006
  • The estimation of the work of heart can be treated as one of the most important parameters for determining the amount of circulating blood needed for harmonious metabolism in the human body. By monitoring the work of heart, one can detect increased work load of heart and start the treatment at the early stage of CHF. Thus it is necessary to estimate the work of heart. The contractility of the left ventricle, the second important parameter for representing the motion of heart, can be estimated through information on the work of heart. In this study, the modified Windkessel model, which has been used for a measure of vascular hemodynamic impedance parameters, was adapted to estimate the work of heart.

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Screening of the Positive Inotropic Activity of Medicinal Plants Used in Oriental Medicine

  • Choi, Deok-Ho;Kang, Dae-Gil;Kim, Seung-Ju;Cui, Xun;Lee, Ho-Sub
    • 동의생리병리학회지
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    • 제20권3호
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    • pp.730-734
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    • 2006
  • Aqueous extracts of medicinal plants traditionally used in the East Asia such as China, Korea, and Japan were screened for inotropic activity using isolated rabbit atria. Among the twenty-one aqueous-extracts from medicinal plants, the aqueous extracts of Convallaria keiskei(ACK) and rhizome of Coptis chinesis (ACC) were found to exhibit distinctive positive inotropic activity. The aqueous extracts of C. keiskei and rhizome of C. chinensis significantly increased atrial stroke volume and pulse pressure in beating rabbit atria. These findings suggest that the aqueous extracts of C. keiskei and rhizome of C. chinensis enhance the cardiac muscle contractility and then could be useful for the treatment of cardiac failure.

능동운동과 수동운동이 운동조절에 미치는 영향 (The Effects of Motor Control with Active Movement and Passive Movement)

  • 배성수;김철용;황보각;정현애;최재원
    • The Journal of Korean Physical Therapy
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    • 제11권3호
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    • pp.13-21
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    • 1999
  • Active movement is able to actively contract his muscles and move a segment either with or without assistance. This movement maintain physiologic elasticity and contractility of the participating muscles, provide sensory feedback from the contracting muscles and stimulus for bone integrity as well as increase circulation and prevent thrombus formation, in addition to develop coordination and moor skills for functional activities. Passive movement is the motion to the external force; gravity, machine, another individuals. Active movement is more activated rather than passived on the central nervous system. Therefore, we think that active movement is more effected facilitating through specific inhibitory mobilization of muscle.

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