• Title/Summary/Keyword: continuous functions

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The Effect of Virtual Reality Based Rehabilitation Program on Balance of Patient with Stroke: A Meta-analysis of Studies in Korea (가상현실기반 재활프로그램이 뇌졸중환자의 균형에 미치는 영향 : 국내연구에 대한 메타분석)

  • Roh, Jung-suk
    • Journal of Korean Physical Therapy Science
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    • v.24 no.1
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    • pp.59-68
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    • 2017
  • Purpose : The aims of this study was to conduct a systematic literature review with meta-analysis to investigate the effect of virtual reality based rehabilitation program on balance of patient with stroke in Korean studies. Method : The studies for analysis were searched in electronic databases(Research Information Sharing Service; RISS, Korean Studies Information Service; KISS, DBpia, e-articles, National Assembly Library). The key words for search were 'virtual reality', 'stroke', and 'balance' and only randomized controlled trials and clinical controlled trials were included. Of 40 studies identified in the search, 20 studies met the criteria of this study and included in this meta-analysis. Result : The results were as follows: 1) The overall effect size of virtual reality based rehabilitation program was 0.557(95% critical interval; 0.340~0.774). 2) In the analysis of sub-categorical variables, effect size was as follows; the commercial game type(0.621) > virtual environment type(0.335); the dynamic balance measurement(0.750) > static balance measurement(0.226); randomized controlled trial(0.653) > clinical controlled trial(0.275); and thesis type(0.706) > article of journal type(0.339). 3) In the analysis of sub-continuous variables, as time of program(per session) increased, the balance increased(p<0.05). Conclusion : The results of this study showed that virtual reality based rehabilitation program moderately improves the balance of stroke patient. Further studies are recommended to investigate the effect of sub-variables related to virtual reality programs on motor functions of patient with stroke.

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Overproduction of the Escherichia coli Chaperones GroEL-GroES in Rhodococcus ruber Improves the Activity and Stability of Cell Catalysts Harboring a Nitrile Hydratase

  • Tian, Yuxuan;Yu, Chen, Huimin;Shen, Zhongyao
    • Journal of Microbiology and Biotechnology
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    • v.26 no.2
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    • pp.337-346
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    • 2016
  • Three combinations of molecular chaperones from Escherichia coli (i.e., DnaK-DnaJ-GrpE-GroEL-GroES, GroEL-GroES, and DnaK-DnaJ-GrpE) were overproduced in E. coli BL21, and their in vitro stabilizing effects on a nitrile hydratase (NHase) were assessed. The optimal gene combination, E. coli groEL-groES (ecgroEL-ES), was introduced into Rhodococcus ruber TH3. A novel engineered strain, R. ruber TH3G was constructed with the native NHase gene on its chromosome and the heterologous ecgroEL-ES genes in a shuttle plasmid. In R. ruber TH3G, NHase activity was enhanced 37.3% compared with the control, TH3. The in vivo stabilizing effect of ecGroEL-ES on the NHase was assessed using both acrylamide immersion and heat shock experiments. The inactivation behavior of the in vivo NHase after immersion in a solution of dynamically increased concentrations of acrylamide was particularly evident. When the acrylamide concentration was increased to 500 g/l (50%), the remaining NHase activity in TH3G was 38%, but in TH3, activity was reduced to 10%. Reactivation of the in vivo NHases after varying degrees of inactivation was further assessed. The activity of the reactivated NHase was more than 2-fold greater in TH3G than in TH3. The hydration synthesis of acrylamide catalyzed by the in vivo NHase was performed with continuous acrylonitrile feeding. The final concentration of acrylamide was 640 g/l when catalyzed by TH3G, compared with 490 g/l acrylamide by TH3. This study is the first to show that the chaperones ecGroEL-ES work well in Rhodococcus and simultaneously possess protein-folding assistance functions and the ability to stabilize and reactivate the native NHases.

Seismic Fragilities of Bridges and Transmission Towers Considering Recorded Ground Motions in South Korea (한국의 지반거동을 고려한 교량과 송전철탑의 지진취약도 분석)

  • Park, Hyo Sang;Nguyen, Duy-Duan;Lee, Tae-Hyung
    • Journal of the Earthquake Engineering Society of Korea
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    • v.20 no.7_spc
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    • pp.435-441
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    • 2016
  • The Korean peninsula has known as a minor-to-moderate seismic region. However, some recent studies had shown that the maximum possible earthquake magnitude in the region is approximately 6.3-6.5. Therefore, a seismic vulnerability assessment of the existing infrastructures considering ground motions in Korea is necessary. In this study, we developed seismic fragility curves for a continuous steel box girder bridge and two typical transmission towers, in which a set of seven artificial and natural ground motions recorded in South Korea is used. A finite element simulation framework, OpenSees, is utilized to perform nonlinear time history analyses of the bridge and a commercial software, SAP2000, is used to perform time history analyses of the transmission towers. The fragility curves based on Korean ground motions were then compared with the fragility curves generated using worldwide ground motions to evaluate the effect of the two ground motion groups on the seismic fragility curves of the structures. The results show that both non-isolated and base-isolated bridges are less vulnerable to the Korean ground motions than to worldwide earthquakes. Similarly to the bridge case, the transmission towers are safer during Korean motions than that under worldwide earthquakes in terms of fragility functions.

A New Hybrid Evolutionary Programming Technique Using Sub-populations with Different Evolutionary Behaviors and Its Application to Camera Calibration (서로 다른 진화 특성을 가지는 부집단들을 사용한 새로운 하이브리드 진화 프로그래밍 기법과 카메라 보정 응용)

  • 조현중;오세영;최두현
    • Journal of the Korean Institute of Telematics and Electronics C
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    • v.35C no.9
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    • pp.81-92
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    • 1998
  • A new hybrid technique using several sub-populations having completely different evolutionary behaviors is proposed to increase the possibility to quickly find the global optimum of continuous optimization problem. It has three sub-populations. Two NPOSA algorithms showing good performance in the problem having a rugged fitness function are applied to two sub-populations and a self-adaptive evolutionary algorithm to the other sub-population. Sub-populations evolve in different manners and the interaction among these sub-populations lead to the global optimum quickly. The efficiency of this technique is verified through benchmark test functions. Finally, the algorithm with three sub-populations has been applied to seek for the optimal camera calibration parameters. After an error function has been defined using measured feature points of a calibration block, it has been shown that the algorithm searches for the camera parameters that minimize the error function.

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Assessing Unit Hydrograph Parameters and Peak Runoff Responses from Storm Rainfall Events: A Case Study in Hancheon Basin of Jeju Island

  • Kar, Kanak Kanti;Yang, Sung-Kee;Lee, Jun-Ho
    • Journal of Environmental Science International
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    • v.24 no.4
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    • pp.437-447
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    • 2015
  • Estimation of runoff peak is needed to assess water availability, in order to support the multifaceted water uses and functions, hence to underscore the modalities for efficient water utilization. The magnitude of storm rainfall acts as a primary input for basin level runoff computation. The rainfall-runoff linkage plays a pivotal role in water resource system management and feasibility level planning for resource distribution. Considering this importance, a case study has been carried out in the Hancheon basin of Jeju Island where distinctive hydrological characteristics are investigated for continuous storm rainfall and high permeable geological features. The study aims to estimate unit hydrograph parameters, peak runoff and peak time of storm rainfalls based on Clark unit hydrograph method. For analyzing observed runoff, five storm rainfall events were selected randomly from recent years' rainfall and HEC-hydrologic modeling system (HMS) model was used for rainfall-runoff data processing. The simulation results showed that the peak runoff varies from 164 to 548 m3/sec and peak time (onset) varies from 8 to 27 hours. A comprehensive relationship between Clark unit hydrograph parameters (time of concentration and storage coefficient) has also been derived in this study. The optimized values of the two parameters were verified by the analysis of variance (ANOVA) and runoff comparison performance were analyzed by root mean square error (RMSE) and Nash-Sutcliffe efficiency (NSE) estimation. After statistical analysis of the Clark parameters significance level was found in 5% and runoff performances were found as 3.97 RMSE and 0.99 NSE, respectively. The calibration and validation results indicated strong coherence of unit hydrograph model responses to the actual situation of historical storm runoff events.

Multiple Model Adaptive Estimation of the SOC of Li-ion battery for HEV/EV (다중모델추정기법을 이용한 HEV/EV용 리튬이온전지의 잔존충전용량 추정)

  • Jung, Hae-Bong;Kim, Young-Chol
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.1
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    • pp.142-149
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    • 2011
  • This paper presents a new state of charge(SOC) estimation of large capacity of Li-ion battery (LIB) based on the multiple model adaptive estimation(MMAE) method. We first introduce an equivalent circuit model of LIB. The relationship between the terminal voltage and the open circuit voltage(OCV) is nonlinear and may vary depending on the changes of temperature and C-rate. In this paper, such behaviors are described as a set of multiple linear time invariant impedance models. Each model is identified at a temperature and a C-rate. These model set must be obtained a priori for a given LIB. It is shown that most of impedances can be modeled by first-order and second-order transfer functions. For the real time estimation, we transform the continuous time models into difference equations. Subsequently, we construct the model banks in the manner that each bank consists of four adjacent models. When an operating point of cell temperature and current is given, the corresponding model bank is directly determined so that it is included in the interval generated by four operating points of the model bank. The MMAE of SOC at an arbitrary operating point (T $^{\circ}C$, $I_{bat}$[A]) is performed by calculating a linear combination of voltage drops, which are obtained by four models of the selected model bank. The demonstration of the proposed method is shown through simulations using DUALFOIL.

A Study on Public Design Project Management Process In Terms of Design Management (디자인경영 측면에서 본 공공디자인사업 관리프로세스에 관한 연구)

  • Park, Su-Kyoung;Moon, Jeong-Min
    • Korean Institute of Interior Design Journal
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    • v.21 no.6
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    • pp.71-78
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    • 2012
  • These days, design has been used a very useful means to achieve differentiated urban images and establish the identity of a city, and as an effort to specialize local industries through design, public design projects are competing one another. However, the projects have considerable negative effects because of diverse reasons such as unorganized procedures. For continuous and organized projects which meet demands of the interested persons of public design, reasonable design management should be introduced with a use of design as a strategic means of management Therefore, this study examined the concepts of design management and its meaning in space and analysed cases of implementing components for management of public design projects. It searched for the factors of design management indicating design-oriented management and presented a strategy model which complements design-oriented management. The results of the study are presented as follows: First, strategic implementing components needed for a space design management process were obtained. A design recognition process aimed at what space aims at and needed to identify active components such as physical and indigenous environment. A design inquiry process included problem solution considering characteristics of multi-dimensional space active components, design development considering behavioral functions of humans, checklists needed to complete design and necessary components to institutionalize design. For definition of project space, guideline projects of public design should be progressed in the same context as urban design, and developmental directions of public design needed design inquiry in terms of space to create various experiences in space.

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Design and Development of Digital Contents Authoring System for Cyber University Using Programing Skills (프로그래밍 기법을 활용한 가상대학 컨텐츠 제작 시스템 설계 및 개발)

  • Cho Sae-Hong
    • Journal of Digital Contents Society
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    • v.2 no.1
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    • pp.1-7
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    • 2001
  • The authoring systems for digital contents using multimedia technologies ate requested in many fields such as education, medical science, entertainment market e-commerce and etc. Especially, the emergence of cyber universities and the rapid expansion of on-line education market require the effective contents authoring systems, which have various functions to generate the qualified contents. Therefore, many systems arc developed and currently used. However, since the developed systems considered only the developer's convenience, the generated digital contents by using these systems are failed to draw tile users'(or learners') active interaction with contents. That is, since the users just watch the contents like watching a drama or a film, it causes many problems in delivering the contents effectively or in evaluating the users. This paper presents, develops, and implements the new contents authoring system by using programing languages and/or software tools. The presented, developed, and implemented system mimics the face-to-face education in off-line system, induces the users' active interaction with contents, and continuous evaluation to the users.

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Design of Navigation Environment Generation Module of M&S Software for Integrated Navigation System Performance Evaluation

  • Kim, Heyone;Lee, Junhak;Oh, Sang Heon;So, Hyoungmin;Hwang, Dong-Hwan
    • Journal of Positioning, Navigation, and Timing
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    • v.7 no.2
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    • pp.73-90
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    • 2018
  • Various navigation systems are integrated with the Global Navigation Satellite System (GNSS) to improve navigation performance so that continuous navigation information can be obtained even when navigation performance is degraded or navigation is not available due to the outage of GNSS. Time and cost can be reduced by evaluating performance of the integrated navigation system through Modeling and Simulation (M&S) software prior to the deployment of the integrated navigation system. The measurements of the navigation system should be generated to evaluate performance through of the navigation system M&S software. This paper proposes a method of designing a navigation environment generation module in M&S software of the integrated navigation system. To show applicability of the proposed method to M&S software design of the integrated navigation system, functions are verified through MATLAB. And then visual C++ based M&S software for the integrated navigation system is implemented to check the operation of the navigation environment generation module. The reference trajectory is generated and true measurements of Global Positioning System (GPS), Korea Positioning System (KPS), and enhanced Long range navigation (eLoran) are generated from the reference trajectory. The navigation results obtained from the true measurements are compared with the reference trajectories. The results show that the measurements generated using the design generation module by the proposed method are valid and the navigation environment generation module can be applied to M&S software of the integrated navigation system.

A Study on the Effect of Arch Support for Improvement of Muscle Activity (운동효과 증진을 위한 Arch Support 효과에 관한 연구)

  • Lee, Chang-Min;Kim, Jin-Hoon;Oh, Yeon-Ju;Kim, Dae-Woong
    • Journal of the Ergonomics Society of Korea
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    • v.27 no.3
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    • pp.71-79
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    • 2008
  • Walking shoes for walking and jogging have been used to enjoy lots of leisure time. Functional shoes such as walking shoes have special functions to improve body motility by changing of shoe shapes. The walking shoes could improve the motility by structural transformation of outsole as increase degrees of heel and toe. The study on insoles has not been conducted enough on the contrary of the study of outsole. The purpose of this study is to perform ergonomics analysis whether the Arch Supported insoles have an improving effect of muscle activities or not. Experiments were performed with 6 subjects who are health and haven't experienced any diseases past. EMG(Electromyography) and Foot Pressures were measured repeatedly for 5 seconds at 0 hour, after 1 hour and after 2 hours of walking. Insoles used for experiment are normal insole, insole inserted Arch Support and pad. The electrodes for EMG measurement were set on waist (erector spinae), and thigh (vastus lateralis), calf (gastrocnemius). Evaluations of EMG were analyzed by shift of MF (Median Frequency) and MPF (Mean Power Frequency). Foot Pressure was analyzed by mean pressure of feet and change of walking time. As results, Arch Support insole had larger frequency shift value than that of normal insole. Frequency shift between Arch Support insoles and normal insole showed significant difference on 95% confidence interval. And insole 1 has the highest value of frequency shift. For results of foot pressure, Arch Support insoles show continuous decreasing tendency when comparing with normal insoles by changing of times. Also, insole 1 has the highest decreasing value of foot pressure. Therefore, this study presented that the Arch Support insole can promote muscle activities and improves comfort for a prolonged walking.