• Journal of Ginseng Research
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• v.22 no.3
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• pp.173-180
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• 1998

Thrombogenesis and atherosclerosis are mainly caused by platelet aggregation, blood coagulation, and hyperlipidemia. Platelet aggrelation, activated platelet thromboplastin time (APTT) were measured as indexes of blood coagulation and lipid contents in the subjects who have taken red ginseng products (e.g. water extract, tea, drink etc.) for 4 to 5 years. The platelet aggregation in the red ginseng-taking group was significantly decreased, as compared with the non-red ginseng-intaking group, when platelets were stimulated by 100 $\mu\textrm{g}$/ml of collagen (P<0.01). The atherogenic index and the ratio of triglyceride to HDL-cholesterol in blood, the risk factors of atherosclerosis, were decreased in the subjects of ginseng group, compared with that in control group. APTT was also prolonged to greater extent in ginseng group than in control group. These results suggest that long-term intake of ginseng products may help to prevent the risks of thrombogenesis and atherosclerosis.

• The Korea Journal of Herbology
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• v.28 no.3
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• pp.39-44
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• 2013

Objectives : The purpose of this study was to identify active fraction and components from antiplatelet Ulmi cortex extract. Methods : The 70% ethanol extract of Ulmi cortex was subjected to column chromatography over D101 resin and eluted with an 20% (W1), 30% (W2), 40% (W3), 50%(W4), 70% (W5), and 100% ethanol (W6) to yield 6 fractions. W6 was further fractioned and its active components were purified using semi-preparative HPLC. The isolated compounds were identified by MS and NMR, and their contents were simultaneously analyzed using HPLC/UV. Antiplatelet aggregation activities of the fractions and the compounds were evaluated using rat platelet-rich plasma in presence of collagen ($5{\mu}g/ml$), arachidonic acid (0.05 U/ml), or thrombin ($100{\mu}M$). Results : Among six fractions, W3 prominently inhibited platelet aggregation. At the concentration of $200{\mu}g/ml$, W3 strongly inhibited arachidonic acid- and collagen-induced platelet aggregations by 78.2% and 65.9%, respectivley, and weakly inhibited thrombin-inducded platelet aggregation by 32.6%. Catechin, epicatehin, and catechin-7-O-${\beta}$-D-glucopyranoside were isolated from W3 and their contents were revealed to be 15.1%, 0.87%, and 0.32%. Catechin and epicatechin at the concentrations of $100{\mu}M$ strongly inhibited collagen-induced platelet aggregation by 79.9% and 86.6%, respectively, but weakly inhibited arachidonic acid- and thrombin-induced platelet aggregations. Conclusions : A main active principle of anitplatelet Ulmi Cortex extract is W3 fraction, of which main active component is catechin considering its antiplatelet activity and content.

• The Journal of the Korea Contents Association
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• v.7 no.5
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• pp.1-9
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• 2007

Topology information can be constructed hierarchically in the networks and the process of aggregating topology information is known as TA(Topology Aggregation). It is very important for scalability in networks. In paticular, routing and TA algorithm are very much elements on networks performance in private networks to networks interface. Therefore, in this paper, we designed and implemented routing simulator for TA in private networks to networks interface. And we evaluated and analyzed the existent TA algorithm using the implemented simulator. The implemented simulator can be used valuably to developing TA algorithm.

• Journal of the Korea Society of Computer and Information
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• v.10 no.3 s.35
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• pp.101-110
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• 2005

A virtual locator is a logical locator based on the contents of a physical locator. These contents can be existing member properties in the physical locator. Using virtual locator, we can accomplish personalization which is the technology area associated most often with CRM. In this study, however, what are called virtual locators in many OLAP models would be treated as physical locators for many unique aggregation levels. By using physical locators, we can bring a successful e-business.

• Proceedings of the Korea Contents Association Conference
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• 2007.11a
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• pp.405-409
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• 2007

The RSS which is a kind of syndication technology enables a part or the whole of the content which it provides from web site to be able to be used in different service. It is protocol to summarize and share various contents on web site. This Paper propose the ways to implement system to aggregate RSS feed and archive it and the services using it. Also, the users register the channel RSS to the RSS aggregator system and recommend it. It can drive to share of knowledge between researchers.

• The Journal of Society for e-Business Studies
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• v.14 no.2
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• pp.41-56
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• 2009

The purpose of this paper is to present a statistical model that can predict the rapid shift of users' attention by analyzing the lifecycle patterns of news in a social news aggregation service. Internet news service sites have a distinct characteristic in a sense that users' attention change very quickly in a short period of time. In this research, we propose a regression model for each news category which can model the decay pattern of users' attention and the content promotion policy of a social news aggregator is proven to be a major source of the rapid growth in the popularity of news. The proposed model is expected to be useful for evaluation of the social news aggregation service provider's content promotion policy that attempts to maximize users' attention as well as the diversity of news contents.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.10
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• pp.1361-1370
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• 2018

With the advent of OTT, the new concept of content delivery service is growing interest in the market, the development of appropriate equipment and application program is needed. In order to provide OTT service, a system to receive UHD broadcast to collect free content is needed. In this study, we designed an OTT service providing system that operates on 4K UHD video adapter hardware capable of IPTV service. First, we analyzed the situation to provide video free contents service and implemented a system to collect free contents. To validate the research and to make practical use of it, we have developed a mobile program for free content service and distributed it through the Google App Store. It is also installed in an OTT box with the ability to provide free content on the open market and is in service in several countries including Brazil.

• The Journal of the Korea Contents Association
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• v.9 no.7
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• pp.67-75
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• 2009

IEEE 802.11 WLAN(Wireless Local Area Network) standard is currently developing with increased wireless internet demand. Study trends of IEEE 802.11n for high throughput show two aspects, enhanced system throughput using aggregation among packets in MAC(Medium Access Control) layer, and better data rates adapting MIMO(Multiple-Input Multiple-Output) in PRY(Physical) layer. But, no one demonstrates IEEE 802.11n system performance results considering MAC and PRY connection. This paper adapts A-MPDU(Aggregation-MAC Protocol Data Unit) method in MAC layer and MIMO in PRY layer for IEEE 802.11n system. Consequently, Simulation results show enhanced throughput and data rates compared to existing system. Also, We use NS-2(Network Simulator-2) considering MAC and PRY connection for reality.

• The Journal of Korean Medicine
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• v.23 no.2
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• pp.164-179
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• 2002

Object: Death rate due to hypertension, atherosclerosis, ischemic heart disease and cerebral infarction induced by Westernized diet and increased average life span is on the rise. Decrease in blood circulation, activation of thrombus generation and intravascular lipid accumulation, cited as the principal causes of the above mentioned diseases in recent studies, result in circulatory disturbance and blood vessel obstruction leading to ischemic cell death of heart, brain and peripheral vessels. Method: We investigated the biochemical changes in microvascular permeability, aggregation of platelet and the intravascular lipid accumulation in induced-diabetic rat using Streptozotocin. We also studied the effects of Woohwangcheongsirn-won after oral administration on blood circulation, platelet function and lipid metabolism. The results are as follows: I. Woohwangcheongsim-won increased blood circulation in microvessels. 2. Woohwangcheongsim-won increased the reduced erythrocyte deformability in diabetes. 3. Woohwangcheongsim-won induced the reduction of contents of 2, 3-DPG, but failed to affect the reduced contents of ATP in erythrocyte in diabetes. 4. Woohwangcheongsim-won reduced the activity of Ca/sup 2+/-ATPase in the membrane of erythrocyte. 5. Woohwangcheongsim-won reduced the platelet aggregation evoked by platelet agglutinin factor. 6. Woohwangcheongsim-won reduced the production of platelet-derived granules. 7. Woohwangcheongsim-won reduced the production of metabolites of arachidonic acid in diabetes, and also reduced the production of increased thromboxane B2. 8. Woohwangcheongsim-won reduced the synthesis of oxidized LDL-cholesterol. In conclusion, Woohwangcheongsim-won enhanced blood circulation in microvesseles, erythrocyte deformability and inhibited the increased platelet aggregation and the synthesis of oxidized LDL-cholesterol in diabetes. Therefore Woohwangcheongsim-won is believed to positively affect blood circulation (J Korean Oriental Med 2002;23(2):164-179)

• Bulletin of the Korean Chemical Society
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• v.28 no.5
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• pp.795-799
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• 2007

The bulk properties of poly(γ-benzyl-L-glutamate)-poly(ethylene glycol), PBLG-PEO, diblock copolymer were investigated. The helical transition from 7/2 to 13/5 for pure PBLG was at 120 oC while those of GE-1 and GE-2, which contain flexible PEO block 40 wt% and 60 wt% respectively, were shown at 135℃ on DSC experiments. FT-IR and XRD experiments were shown that the diblock copolymers maintained their α-helical structure in the temperature range between 25℃ and 175℃. Increasing relative size of coil part resulted in the increase of intermolecular packing distances. Due to well-maintained helical structure, lyotropic LC phases were observed for the PBLG-PEO block copolymer by the polarized optical microscope (POM). Especially, GE-3 copolymer, which has 12.5 wt% PEO contents, showed the smectic C phase. The competition of favorable aggregation energy between rod-rod and coil-coil, and unfavorable aggregation energy of rod-coil give rise to change the supramolecular structure in mixed solvent.