• The Transactions of the Korean Institute of Power Electronics
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• v.19 no.5
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• pp.463-469
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• 2014

This paper proposes a maximum torque operation strategy for the direct torque control of a surface-mounted permanent-magnet synchronous motor (SPMSM). The proposed method analyzes the available operation region of the stator flux of the SPMSM under voltage and current constraints. Based on this analysis, the optimal stator flux trajectory that yields the maximum torque is obtained across the entire operation region, including constant torque and constant power regions. The proposed strategy is also applicable in the flux-weakening region II operation of the SPMSM, which has no speed limit. The validity of the proposed method is verified through experiments conducted on an 800 W SPMSM drive system.

• Biotechnology and Bioprocess Engineering:BBE
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• v.10 no.5
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• pp.425-431
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• 2005

The systems-level analysis of microbes with myriad of heterologous data generated by omics technologies has been applied to improve our understanding of cellular function and physiology and consequently to enhance production of various bioproducts. At the heart of this revolution resides in silico genome-scale metabolic model, In order to fully exploit the power of genome-scale model, a systematic approach employing user-friendly software is required. Metabolic flux analysis of genome-scale metabolic network is becoming widely employed to quantify the flux distribution and validate model-driven hypotheses. Here we describe the development of an upgraded MetaFluxNet which allows (1) construction of metabolic models connected to metabolic databases, (2) calculation of fluxes by metabolic flux analysis, (3) comparative flux analysis with flux-profile visualization, (4) the use of metabolic flux analysis markup language to enable models to be exchanged efficiently, and (5) the exporting of data from constraints-based flux analysis into various formats. MetaFluxNet also allows cellular physiology to be predicted and strategies for strain improvement to be developed from genome-based information on flux distributions. This integrated software environment promises to enhance our understanding on metabolic network at a whole organism level and to establish novel strategies for improving the properties of organisms for various biotechnological applications.

• Journal of Microbiology and Biotechnology
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• v.18 no.11
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• pp.1773-1784
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• 2008

Effects of various industrially important carbon sources (glucose, sucrose, xylose, gluconate, and glycerol) on shikimic acid (SA) biosynthesis in Escherichia coli were investigated to gain new insight into the metabolic capability for overproducing SA. At the outset, constraints-based flux analysis using the genome-scale in silico model of E. coli was conducted to quantify the theoretical maximum SA yield. The corresponding flux distributions fueled by different carbon sources under investigation were compared with respect to theoretical yield and energy utilization, thereby identifying the indispensable pathways for achieving optimal SA production on each carbon source. Subsequently, a shikimate-kinase-deficient E. coli mutant was developed by blocking the aromatic amino acid pathway, and the production of SA on various carbon sources was experimentally examined during 51 batch culture. As a result, the highest production rate, 1.92 mmol SA/h, was obtained when glucose was utilized as a carbon source, whereas the efficient SA production from glycerol was obtained with the highest yield, 0.21 mol SA formed per mol carbon atom of carbon source consumed. The current strain can be further improved to satisfy the theoretically achievable SA production that was predicted by in silico analysis.

• Journal of computational fluids engineering
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• v.8 no.3
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• pp.56-65
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• 2003

A numerical procedure for analyzing the heat transfer in a regenerative cooling passage of liquid rocket has been developed. The thermal analysis is based on the numerical model of Naraghi〔1〕. The thermodynamic and transport properties of the combustion gases are evaluated using the chemical equilibrium composition. The pressure and heat flux obtained by the isentropic relation are in good agreement with the result of Navier-Stokes equations. The effect of design parameters on heat transfer is addressed for the pressure loss and temperature variation. Also, their constraints in designing the cooling passage are recommended. Finally, in a heated rectangular duct, the effects of secondary flow on heat transfer are scrutinized by the nonlinear k- e -fu of Park et at.〔2〕.

• Transactions of the Korean Society of Mechanical Engineers
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• v.17 no.1
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• pp.141-152
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• 1993

A generalized method is presented for shape design sensitivity analysis of axisymmetric thermal conducting solids. The shape sensitivity formula of a general performance functional arising in shape optimal design problem is derived using the material derivative concept and the adjoint variable method. The method for deriving the formula is based on standard axisymmetric boundary integral equation formulation. It is then applied to obtain the sensitivity formulas for temperature and heat flux constraints imposed over a small segment of the boundary. To show the accuracy of the sensitivity analysis, numerical implementations are done for three examples. Sensitivities calculated by the presented method are compared with analytic sensitivities for two examples with analytic solutions, and compared with sensitivies by finite difference for a cooling fin example.