• Title/Summary/Keyword: constituent components

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Hypoglycemic Effect of Yacon Tuber Extract and Its Constituent, Chlorogenic Acid, in Streptozotocin-Induced Diabetic Rats

  • Park, Jeong-Sook;Yang, Jae-Sik;Hwang, Bang-Yeon;Yoo, Bong-Kyu;Han, Kun
    • Biomolecules & Therapeutics
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    • v.17 no.3
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    • pp.256-262
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    • 2009
  • Smallanthus sonchifolius (Yacon, Asteraceae) was originally cultivated in South America and used in food and traditional medicine by Andean inhabitants. Yacon is potentially beneficial for the management of diabetes and is composed of fructooligosaccharides, proteins, minerals and phenolic compounds. The aim of this study was to investigate the hypoglycemic effect of Yacon tuber extract (YTE) and its constituent, chlorogenic acid (CGA), in streptozotocin (STZ)-induced diabetic rats. In this study, a HPLC method was developed for simultaneous determination of major active phenolic components, CGA and caffeic acid in YTE. We investigated the hypoglycemic effect of YTE and CGA in STZ-induced diabetic rats and studied glucose tolerance test (GTT). The effect of orally administered multiple doses of YTE and CGA on plasma biochemical parameters was examined using diabetic rats. We also measured free radical scavenging activity by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. Oral administration of YTE (200 mg/kg) and CGA (10 mg/kg) for 6 weeks produced a significant hypoglycemic effect in STZ-induced diabetic rats. YTE and CGA-treated groups exhibited significantly decreased plasma glucose surge during the GTT. Total cholesterol (TC) and triglyceride (TG) concentrations were significantly decreased by 33% and 49%, respectively, in YTE-treated rats. TC and TG concentrations were also significantly decreased by 26 % and 41%, respectively, in CGA-treated rats. In the DPPH assay, free radical scavenging activity of CGA was similar to that of vitamin E, a positive control. This study suggests that YTE and its constituent, CGA, may be a useful option for management of hyperglycemia and diabetic nephropathy.

Resources Evaluation System for Rural Planning Purposes( I ) - Formulation of Goal System for Resource Evaluation - (농촌계획지원용 지역자원평가시스템 구축(I) - 자원평가 구성요소의 목표체계 구축 -)

  • 최수명;황한철
    • Journal of Korean Society of Rural Planning
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    • v.3 no.1
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    • pp.54-67
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    • 1997
  • Korean societies have been experiencing the wholesale structural changes in the rapid currents of recent openness, globalization and democratization, which effect much more heavily in rural areas than in urban areas, so rural recomposition works being an important national concern. In order to systematically reconstruct the rural structure, the decision makers, with a four step hierarchy of rural resident-residents group-community-region, should be endowed with the objective judgement on basic elements of resource potentialities under their control. In this process. rational resource evaluation works would be firstly necessiated from expert groups. Based on the view mentioned above, this study principally aimed at developing a rational evaluation framework for rural resources. For that objective, the first step of the study pigeonholed the total resources items identifiable in rural areas from the existing study results, spatial planning and field surveying data. After then, using the formalized classification criteria of resources items, a tentative goal system for rural resources evaluation was proposed and the final one determined through expert-group checking. The results obtained during the study are summarized as follows ; 1. Using the existing examples of resources identification/classification and the basic data list for county-level development planning as the principal reference ones, total rural resources elements were classified into 3 constituent units : land, natural environment and human resources, which correspond to places to work, to play and to live, respectively, as 3 constituent ones of life-supporting space. 2. Three characteristic areal types were adopted to represent the total rural areas : lowland, upland and seashore areas, and also 3 practical use types to represent the objectives of resources evaluation systems : for land use planning, natural conservation policy and village improvement planning. Thus 9 different types of goal system for resources evaluation were developed(each system by 3 areal typesX3 practical use types) 3. Each goal system has 3-tier classification steps from the higher, middle and lower one. The higher and middle steps should contain equally applicable components to all the rural areas, of which allowable number being around 3 and 4 respectively. However the lower step would contain detailed sub-components changeable to areal characteristics of which allowable number being around 7.

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Volatiles of Chrysanthemum zawadskii var. latilobum K.

  • Chang, Kyung-Mi;Kim, Gun-Hee
    • Preventive Nutrition and Food Science
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    • v.17 no.3
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    • pp.234-238
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    • 2012
  • The volatile aroma constituents of Chrysanthemum zawadskii var. latilobum K. were separated by hydro distillation extraction (HDE) method using a Clevenger-type apparatus, and analyzed by gas chromatography-mass spectrometry (GC/MS). The yield of C. zawadskii var. latilobum K. flower essential oil (FEO) was 0.12% (w/w) and the color was light green. Fifty-five volatile chemical components, which make up 88.38% of the total aroma composition, were tentatively characterized. C. zawadskii var. latilobum K. FEOs contained 27 hydrocarbons, 12 alcohols, 7 ketones, 4 esters, 1 aldehyde, 1 amine, and 3 miscellaneous components. The major functional groups were terpene alcohol and ketone. Borneol (12.96), (${\pm}$)-7-epi-amiteol (12.60), and camphor (10.54%) were the predominant volatiles. These compounds can be used in food and pharmaceutical industries due to their active bio-functional properties.

A Study on Development of Safety Index for Evaluating Railway Safety(I) (철도안전도 평가지수 개발에 관한 연구(I) - 안전목표 및 안전지수에 관하여 -)

  • Song, Bo-Young;Lee, Dong-Hoon;Moon, Dae-Seop;Lee, Hi-Sung;Kim, Man-Ung
    • Proceedings of the KSR Conference
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    • 2007.11a
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    • pp.1657-1667
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    • 2007
  • This study propose a model for railway safety evaluation with which the safety of whole railway system can be evaluated. The evaluation model is to generate a safety index which quantitatively represent the degree of railway safety. Safety index is proposed a function of three indexes; an accident index, safety management index, and safety culture index. This paper describes the first result from the study on the safety target which will be a key starting point toward the development of safety evaluation model. It is recommended that the safety target be composed of several sub-targets that are apportioned to constituent components. It is concluded that the classification of safety target influence on deciding components or attributes that constitute each sub-indexes; an accident index, safety management index, and safety culture index. Based on this study, a railway safety evaluation model will be developed in the next study.

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Development of the Assessment Indicators for Railway Safety

  • Song, Bo-Young;Moon, Dae-Seop;Lee, Hi Sung
    • International Journal of Railway
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    • v.5 no.4
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    • pp.175-181
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    • 2012
  • This study proposes a model for railway safety assessment with which the safety of whole railway system can be evaluated. The purpose of the assessment model is to generate safety indicators which quantitatively represent the degree of railway safety. Safety indicators were proposed as three indicators according to their functions; accident indicators, safety management indicators, and safety culture indicators. This paper describes the first result on the safety target which will be a key starting point toward the development of safety assessment model. It is recommended that the safety target to be composed of several sub-targets are apportioned to constituent components. It is concluded that the classification of safety target has influence on deciding components or attributes that constitute each sub-indicators; accident indicators, safety management indicators, and safety culture indicators. Based on this study, a railway safety assessment model will be developed in the following study.

Volatile Aroma Composition of Chrysanthemum indicum L. Flower Oil

  • Chang, Kyung-Mi;Kim, Gun-Hee
    • Preventive Nutrition and Food Science
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    • v.13 no.2
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    • pp.122-127
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    • 2008
  • The aroma constituents of Chrysanthemum indicum L. were separated by the hydro distillation extraction method using a Clevenger-type apparatus, and were analyzed by gas chromatography-mass spectrometry (GC/MS). The yield of Chrysanthemum indicum L. flower oil was 2.0% (w/w) and the color was light golden yellow. Sixty-three volatile flavor components, which make up 89.28% of the total aroma composition of the flower oil, were tentatively characterized. This essential oil contained 35 hydrocarbons (48.75%), 12 alcohols (19.92%), 6 ketones (15.31%), 3 esters (4.61%), 5 aldehydes (0.43%), 1 oxide (0.22%), and 1 miscellaneous component (0.04%). ${\alpha}$-Pinene (14.63%), 1,8-cineol (10.71%) and chrysanthenone (10.01%) were the predominant volatile components in Chrysanthemum indicum L., an aromatic medicinal herbaceous plant.

Qualitative Representation of Spatial Configuration of Mechanisms and Spatial Behavior Reasoning Using Sign Algebra (메커니즘 공간 배치의 정성적 표현과 부호 대수를 이용한 공간 거동 추론)

  • 한영현;이건우
    • Korean Journal of Computational Design and Engineering
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    • v.5 no.4
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    • pp.380-392
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    • 2000
  • This paper proposes a qualitative reasoning approach for the spatial configuration of mechanisms that could be applied in the early phase of the conceptual design. The spatial configuration problem addressed in this paper involves the relative direction and position between the input and output motion, and the orientation of the constituent primitive mechanisms of a mechanism. The knowledge of spatial configuration of a primitive mechanism is represented in a matrix form called spatial configuration matrix. This matrix provides a compact and convenient representation scheme for the spatial knowledge, and facilitates the manipulation of the relevant spatial knowledge. Using this spatial knowledge of the constituent primitive mechanisms, the overall configuration of a mechanism is described and identified by a spatial configuration state matrix. This matrix is obtained by using a qualitative reasoning method based on sign algebra and is used to represent the qualitative behavior of the mechanism. The matrix-based representation scheme allows handling the involved spatial knowledge simultaneously and the proposed reasoning method enables the designer to predict the spatial behavior of a mechanism without knowing specific dimension of the components of the mechanism.

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An experimental study on nucleate boiling of ternary refrigerant R407C (삼중 혼합 냉매 R407C의 핵비등 열전달 특성에 관한 실험적 연구)

  • Kim, S.H.;Kwak, K.M.;Bai, C.H.;Chung, M.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.9 no.3
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    • pp.276-283
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    • 1997
  • The nucleate boiling heat transfer experiments are performed using a ternary refrigerant R407C which is a candidate of alternatives of HCFC 22. The boiling phenomena for R-32, R-125, and R-134a which are the constituent refrigerants of R407C are also investigated to give the foundation of theoretical research for the mixture component boiling. The nucleate boiling heat transfer coefficients of R407C is less than those of HCFC 22 which has the similar physical and transport properties. Since the experimental results show the deterioration of boiling heat transfer coefficients of ternary mixture refrigerants R407C, the boiling heat transfer coefficients of R407C cannot be obtained by the linear combination of boiling heat transfer coefficients from its constituent components R-32, R125, and R134a.

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Analysis of microstructural characteristics and components of red and yellow ink pigments used in permanent makeup

  • Hyun Sook Jin;Byung Soo Chang
    • Applied Microscopy
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    • v.52
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    • pp.3.1-3.8
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    • 2022
  • Our purpose in this study is to analyze the microstructural characteristics and constituent elements of inorganic substances added to the yellow ink and red ink pigments used in permanent makeup. We observed the microstructural properties of inorganic pigments added to the ink using a scanning electron microscopy (SEM) and analyzed the constituent elements of the inorganic pigment particles using an energy dispersive X-ray spectroscopy (EDX). In red wine-colored ink, cubic titanium dioxide with a diameter of 110 to 200 nm was the major component, and rod-shaped iron oxide was rarely observed. Most of the ingredients of taupe yellow ink were rod-shaped yellow iron oxide, and a small amount of cubic titanium dioxide was observed. Red wine-colored ink and taupe yellow ink contained lumps composed of titanium dioxide particles. In red wine-colored ink, lumps were formed by agglomeration. However, we observed that the surface of the lump composed of titanium dioxide in the taupe yellow ink had a smooth surface caused by external physical compression. The titanium dioxide particle mass which found in taupe yellow ink in this study is an artificial product. When this mass accumulates in the dermis, it may cause a color mismatch. Therefore, permanent makeup using fine pigments should be free of foreign substances that may cause trouble in the skin. In addition, there is a need to improve the quality of the ink so that the required color can be safe and long lasting in the dermis.

Conversion Characteristics of Chemical Constituents in Liriodendron tulipifera and Their Influences on Biomass Recalcitrance during Acid-Catalyzed Organosolv Pretreatment

  • Ki-Seob GWAK;JunHo SHIN;Chae-Hwi YOON;In-Gyu CHOI
    • Journal of the Korean Wood Science and Technology
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    • v.52 no.2
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    • pp.101-117
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    • 2024
  • The conversion characteristics of the major components of Liriodendron tulipifera were investigated during acid-catalyzed organosolv pretreatment. Glucan in L. tulipifera was slowly hydrolyzed, whereas xylan was rapidly hydrolyzed. Simultaneous hydrolysis and degradation of xylan and lignin occurred; however, after complete hydrolysis of xylan at higher temperatures, lignin remained and was not completely degraded or solubilized. These conversion characteristics influence the structural properties of glucan in L. tulipifera. Critical hydrolysis of the crystalline regions in glucan occurred along with rapid hydrolysis of the amorphous regions in xylan and lignin. Breakdown of internal lignin and xylan bonds, along with solubilization of lignin, causes destruction of the lignin-carbohydrate complex. Over a temperature of 160℃, the lignin that remained was coalesced, migrated, and re-deposited on the surface of pretreated solid residue, resulting in a drastic increase in the number and content of lignin droplets. From the results, the characteristic conversions of each constituent and the changes in the structural properties in L. tulipifera effectively improved enzymatic hydrolysis in the range of 140℃-150℃. Therefore, it can be concluded that significant changes in the biomass recalcitrance of L. tulipifera occurred during organosolv pretreatment.