• Journal of the Society of Cosmetic Scientists of Korea
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• v.42 no.3
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• pp.203-209
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• 2016

Recently, increased attention has been directed toward medicinal extracts and their active ingredients as potential new drug candidates for androgenic alopecia. Resina Pini (RP), a resinous exudation obtained from Pinus sp. (Pinaceae), has been used as a traditional medicine for the treatment of infection, pain related to dental caries, and periodontal disease. Previously, we suggested that RP and its main constituent, abietic acid (abieta-7,13-dien-18-oic acid; AA), may play important roles against androgenic alopecia as $5{\alpha}$-reductase inhibitors. However, to date, there is no evidence that AA has hair growth-promoting effects in vivo. In this study, we found that 10 ~ 300 mg/kg RP and 3 ~ 30 mg/kg AA significantly promoted hair growth in a C3H/HeN mouse model of alopecia. To our knowledge, this is the first report of the hair growth-promoting effects of RP and AA in vivo. From these results, RP and its main constituent AA can promote hair growth in mouse by inhibiting $5{\alpha}$-reductase activity and may be effective alternative therapies for androgenic alopecia.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 1997.04a
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• pp.34-34
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• 1997

The effect of alloying mode and porosity on the axial tension-tension fatigue behavior of a P/M steel of nominal composition Fe-4w/o Ni-1.5w/o Cu-O.5w/o Mo-O.5w/o C has been evaluated. Alloying modes utilized were elemental powder mixing, partial alloying(distaloy) and prealloying by water atomization; in each case the carbon was introduced as graphite prior to sintering. Powder compacts were sintered($1120{\circ}C$/30 min.) in 7Sv/o $H_2$/25v/o $N_2$ to densities in the range 6.77-7.2 g/$cm^3$. The dependence of fatigue limit response on alloying mode and porosity was interpreted in terms of the constituent phases and the pore and fracture morphologies associated with the three alloying modes. For the same nominal composition, the three alloying modes resulted in different sintered microstructures. In the elemental mix alloy and the distaloy, the major constituent was coarse and fine pearlite, with regions of Ni-rich ferrite, Ni-rich martensite and Ni-rich areas. In contrast, the prealloy consisted primarily of martensite by with some Ni-rich areas. From an examination of the fracture surfaces following fatigue testing it was concluded that essentially all of the fracture surfaces exhibited dimpled rupture, characteristic of tensile overload. Thus, the extent of growth of any fatigue cracks prior to overload was small. The stress amplitude for the three alloying modes at 2x$l0^6$ was used for the comparison of fatigue strengths. For load cycles <3x$l0^5$, the prealloy exhibited optimum fatigue response followed by the distaloy and elemental mix alloy, respectively. At load cycles >2x$l0^6$, similar fatigue limits were exhibited by the three alloys. It was concluded that fatigue cracks propagate primarily through pores, rather than through the constituent phases of the microstructure. A decrease in pore SIze improved the S-N behavior of the sintered steel.

• Korean Journal of Plant Resources
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• v.32 no.4
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• pp.264-269
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• 2019

This research was performed to identify the anti-inflammatory constituent from the herb of Lycorus lucidus (Lamiaceae). The MeOH extract of this plant material and its two fractions, the lipophilic- ($CHCl_3$ fraction) and the hydrophilic fraction (BuOH fraction), were prepared to test anti-inflammatory activity. For this purpose, the inhibition rate on inducible nitric oxide synthase (iNOS) activity was assessed by determining nitric oxide (NO) formation in lipopolysaccharide (LPS)-induced macrophage 264.7 cells. The $CHCl_3$ fraction that greatly inhibited nitric NO formation was chromatographed to lead the isolation of ursolic acid. Since ursolic acid inhibited NO formation dose dependently in this study, this compound was considered as one of the active constituent responsible for anti-inflammation. However, the activity of rosmarinic acid isolated from the BuOH fraction was weak.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.30 no.6B
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• pp.551-560
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• 2010

This study presents the export of constituent transport loads through a river system. The proposed constituent transport load estimating procedure can be operated with the on-going Korean TMDL monitoring system. This study firstly discusses the use of a hydrologic simulation model (TANK) to estimate stream-flow for the 40 sub-catchments. Model parameters are estimated from 8-days intervals flow data which has been monitored by NIER since 2004. Constituent transport loads are estimated with the 7-parameter log linear model whose parameters are estimated by the minimum variance unbiased estimator. Results from Nakdong river basin reveals that the proposed procedure provides satisfactory TN, TP and SS transport load estimates. As an application, a representative load duration curve is derived to represent the overall hydrologic flux of TN, TP and SS at Nakdong river basin.

• The Journal of the Petrological Society of Korea
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• v.27 no.2
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• pp.85-96
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• 2018

The Neoproterozoic Gyemyeongsan Formation and the Mesozoic igneous rocks are distributed in the Eoraesan area, Chungju which is located in the northwestern part of Ogcheon metamorphic zone, Korea, and the rare earth element (REE) mineralized zone has been reported in the Gyemyeongsan Formation. We drew up the detailed geological map by the lithofacies classification, and measured the radioactivity values of the constituent rocks to understand the distribution and characteristics of the source rocks of REE ore body in this paper. It indicates that the Neoproterozoic Gyemyeongsan Formation is mainly composed of metapelitic rock, granitic gneiss, iron-bearing quartzite, metaplutonic acidic rock (banded type, fine-grained type, basic-bearing type, coarse-grained type), metavolcanic acidic rock, and the Mesozoic igneous rocks, which intruded it, are divided into pegmatite, biotite granite, gabbro, diorite, basic dyke. The constituent rocks of Gyemyeongsan Formation show a zonal distribution of mainly ENE trend, and the distribution of basic-bearing type of metaplutonic acidic rock (MPAR-B) is very similar to that of the previous researcher's REE ore body. The Mesozoic biotite granite is regionally distributed unlike the result of previous research. The radioactive value of MPAR-B, which has a range of 852~1217 cps (average 1039 cps), shows a maximum value among the constituent rocks. The maximum-density distribution of radioactive value also agrees with the distribution of MPAR-B. It suggests that the MPAR-B could be a source rock of the REE ore body.

• Journal of Gifted/Talented Education
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• v.18 no.3
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• pp.591-612
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• 2008

In order to investigate the composition and characteristics of instructional objectives in a teaching-learning material for gifted elementary students in science, 217 instructional objectives across 13 themes in 4 areas of 'energy','materials', 'life' and 'earth' were analyzed by Bloom's revised taxonomy of educational objectives. Four types of factual, conceptual, procedural and meta-cognitive knowledge in knowledge dimension were all comprised in the objectives. Conceptual knowledge was primary constituent of the objectives and the proportion of factual knowledge was the least. On the other hand, all 6 categories of 'remember', 'understand', 'apply', 'analyze', 'evaluate' and 'create' in cognitive process dimension were also comprised in the objectives. The category of 'understand' was primary constituent and that of 'remember' was the least one. While conceptual knowledge in knowledge dimension was primary constituent of the objectives in 'energy', 'materials' and 'earth' areas, procedural knowledge was the most objectives in 'life' area. The least type of knowledge was factual knowledge in all 4 areas. In cognitive process dimension, the category of 'understand' was primary constituent and that of 'remember' was the least one in all 4 areas. In conclusion, it was showed that the instructional objectives in the teaching-learning material reflected the characteristics of educational objectives for gifted students in science.

• 한국생물공학회:학술대회논문집
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• 2005.04a
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• pp.450-451
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• 2005

• Proceedings of the Materials Research Society of Korea Conference
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• 2011.10a
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• pp.5-5
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• 2011

Lithium ion batteries are found to have wide range of applications in variety of mobile devices ranging from simple toys to electric vehicles. The performance of these batteries depends on the choice of constituent materials. In this lecture, the materials aspects and perspectives of the electrode batteries will be discussed. Results from some of the specific studies made at speaker's laboratory will be presented.

• Proceedings of the KWS Conference
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• 2005.11a
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• pp.198-200
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• 2005

• Proceedings of the KWS Conference
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• 2007.11a
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• pp.115-117
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• 2007