• Title/Summary/Keyword: connective tissues

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PRELIMINARY STUDY ON HISTOLOGIC CHANGES IN THE NERVE AND SURROUNDING TISSUES AFTER INFERIOR ALVEOLAR NERVE TRANSPOSITION IN RABBITS (토끼 하치조신경 전위술 후의 신경 및 신경주변조직 변화 관찰을 위한 예비 실험)

  • Song, Hyun-Chul
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.25 no.4
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    • pp.350-355
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    • 1999
  • Purpose : The purpose of this study was 1) to find nerve damage after inferior alveolar nerve transposition and 2) to examine whether the soft tissue or bone changes around the nerve produce the compression to the nerve in the healing period. Materials and Method : Inferior alveolar nerve was exposed through the bony window and the scratch was made in the bone to be thought as the inferior alveolar canal. Suture was made after the nerve was repositioned. The nerve and surrounding tissues were examined with the light microscope and the fluorescent microscope before surgery and at 1 month, 3 months, and 5 months after surgery. Results : After surgery, the epineurium was damaged and the nerve was divided to several fascicles covered with the perineurium The newly formed fibrous connective tissue and vessels were seen around fascicles. There was new bone formation. However the nerve was not compressed by the connective tissue or the new bone. Conclusion : The results of this study suggest that neurosensory disturbances after inferior alveolar nerve transposition are resulted by the direct trauma in surgery rather than the compression to the nerve by the scar or new bone formation in the healing period.

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Sectional Differences in Tendon Response

  • Chun, Keyoung-Jin;Robert P. Hubbard
    • Journal of Mechanical Science and Technology
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    • v.17 no.8
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    • pp.1164-1170
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    • 2003
  • The objectives of this work here focus on the differences in responses to multiple cyclic tests of different sections along the length of the same tendon. Tendon specimens were obtained from the hindlimbs of canines and frozen to -70$^{\circ}C$. After thawing, specimens were mounted in the immersion bath at room temperature (22$^{\circ}C$) , preloaded to 0.13 N and then subjected to 3% or 4% of the initial length at a strain rate of 5%/sec. It was found that different sections of the same long tendons had different resistances to deformation. In general, the bone end sections were stiffer and carried greater loads for a given strain than the muscle end sections, and the mid-portions were the least stiff and carried the smallest loads for a given strain. The results of this study offer new information about the mechanical responses of collagenous tissues. We know more about their responses to multiple cyclic extensions and how their responses are different from the positions along the length of the tendon specimen. The nature and causes of these differences in the stiffness are not fully known. However, it is clear that differences in the mechanical response of tendons and other connective tissues are significant to musculoskeletal performance.

Maxillary Ameloblastic Carcinoma in a Shih Tzu Dog

  • Jang, Seong-Hwan;Park, Dae-Sik;Lee, Eun-Sung;Kim, Jae-Hoon
    • Journal of Veterinary Clinics
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    • v.36 no.4
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    • pp.233-237
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    • 2019
  • A 10-year-old castrated male Shih Tzu dog was submitted to a local animal hospital with a mass from gingiva to maxillofacial skeleton. Computed tomography revealed that strong invasion of the mass result in osteolysis in orbit and frontal bone. The excised mass was presented to the Pathology Department of the Veterinary Medicine, Jeju National University. Surgically excised mass was rubbery to firm in consistency. Histologically, the neoplastic mass was composed of irregular or interdigitating cords, islands or pseudo-glandular structures of stratified epithelial cells. These cords or islands showed typical palisading pattern of neoplastic epithelial cells to periphery without intercellular bridge (desmosome) and surrounded by eosinophilic immature collagenous matrix. Some area showed islands of well differentiated keratinizing squamous cell foci. Some lumen of glandular structures contained fibrin-like materials and RBC. These neoplastic cells showed marked invasive tendency to adjacent connective tissues and bony tissues, therefore solitary neoplastic cells were widely distributed throughout the surround connective tissue. The neoplastic cells showed positive reactions for pan-CK and CK14, weakly positive reaction for CK5/6. And the surrounding immature collagenous matrix was only labeled for vimentin.

Morphological studies on hemal nodes and hemolymph nodes in the water deer(Hydropotes inermis) (고라니 혈절과 혈림프절에 관한 형태학적 연구)

  • Yoon, Yeo-sung;Lee, Joon-sup
    • Korean Journal of Veterinary Research
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    • v.37 no.3
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    • pp.463-469
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    • 1997
  • This study was performed to investigate the gross anatomical features and microscopical structures of the hemal nodes and the hemolymph nodes in the water deer (Hydropotes inermis) found in Kangwon-do, Korea. The hemal nodes and hemolymph nodes were observed mainly in the periphery of the thoracic and abdominal aortae of the animals. The size of hemal nodes was generally smaller than that of the hemolymph nodes, and the shape of the both organs was spherical or ovoid. The color of the hemal nodes was red or black while that of the hemolymph nodes was gray with red bands. The hemal nodes were surrounded by a thin connective tissue capsule and there were extensive subcapsular and deep sinuses distended by a great number of erythrocytes. Although a few number of lymphatic nodules and small areas of diffuse lymphatic tissues were observed in the parenchyma, no typical cortex and medulla were defined in the hemal node. Small numbers of blood vessels were found at the connective tissue capsule but lymph vessel was not observed microscopically in this organ. The hemolymph nodes were covered by a relatively thick connective tissue capsule and there was a hilus in each node. The parenchyma was divided into cortex and medulla. The cortex was composed of a few numbers of lymphatic nodules and some diffuse lymphatic tissues. The medulla comprised medullary sinus and cords. Afferent and efferent lymph vessels were observed at the periphery of the capsule and the hilus, respectively. The subcapsular and medullary sinuses were not extensive but filled with small numbers of erythrocytes. The stroma of hemal node and hemolymph node was composed of reticular cells and fibers, and the capsule and trabecula consisted of collagenous fibers with smooth muscle fibers.

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The Effects of Sedum sarmentosum Bunge on Collagen Content of Connective Tissues in Ovariectomized Rats (돌나물이 난소를 절제한 흰쥐 결합조직 중의 Collagen 함량 변화에 미치는 영향)

  • 김미향
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.7
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    • pp.1114-1119
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    • 2003
  • The aim of this study was to evaluate the effects of Sedum sarmentosum Bunge (SS) on the collagen content of the connective tissues in ovariectomized rats. From day 2 until day 37 after the ovariectomy, Sprague-Dawley female rats were randomly assigned to the following groups: sham-operated rats (Sham), ovariectomized control rats (OVX-control), ovariectomized rats supplemented with SS at 50 mg/kg BW/day (OVX-SS50), 100 mg/kg bw/day (OVX-SS100) and 200 mg/kg bw/day (OVX-SS200), and an ethyl ether fraction of SS at 10 mg/kg bw/day (OVX-EE) and an ethyl acetate fraction of SS at 10 mg/kg bw/day (OVX-EA). The SS ethanol extracts and SS fractions were orally administrated 1 mL per day. The OVX rats were significantly heavier than the sham-operated rats at all time points, but supplementation with the SS extracts tended to gain weight less than OVX-control. Supplementation with the SS extracts prevented a decrease in the collagen level in bone and cartilage tissues. These results are consistent with the conclusions based on the estrogenic activities of SS. Therefore, it may be used to possibly improve the quality of life in menopausal women.

Neurobiology and Neurobiomechanics for Neural Mobilization (신경가동성에 대한 신경생물학과 신경생역학적 이해)

  • Kim Jae-Hun;Yuk Goon-Chan;Bae Sung-Soo
    • The Journal of Korean Physical Therapy
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    • v.15 no.2
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    • pp.67-74
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    • 2003
  • Nervous system is clinically important, and involved in most disorders directly or indirectly. It could be injury and be a source of symptoms. Injury of central or peripheral nervous system injury may affect that mechanism and interrupt normal function. An understanding of the concepts of axonal transport is important for physical therapist who treat injury of nerves. Three connective tissue layers are the endoneurium, perineurium, epineurium. Each has its own special structural characteristics and functional properties. The blood supply to the nervous system is well equipped in all dynamic and static postures with intrinsic and extrinsic vasculation. After nerve injury, alternations in the ionic compression or pressures within this environment may interfere with blood flow and, consequently conduction and the flow of axoplasm. The cytoskeleton are not static. On the contrary, elements of the cytoskeleton are dynamically regulated and are very likely in continual motion. It permits neural mobility. There are different axonal transport systems within a single axon, of which two main flows have been identified : First, anterograde transport system, Secondly, retrograde transport system. The nervous system adapts lengthening in two basic ways. The one is that the development of tension or increased pressure within the tissues, increased intradural pressure. The other is movements that are gross movement and movement occurring intraneurally between the connective tissues and the neural tissues. In this article, we emphasize the biologic aspects of nervous system that influenced by therapeutic approaches. Although identified scientific information in basic science is utilized at clinic, we would attain the more therapeutic effects and develop the physical therapy science.

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A Study on the Histopathological Changes of Experimental Bite-marks with the Progress of Time (실험교흔조직의 수상 후 경과시간에 따른 병리조직학적 변화에 관한 연구)

  • 윤창륙;김종열
    • Journal of Oral Medicine and Pain
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    • v.10 no.1
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    • pp.41-52
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    • 1985
  • In order to observe the histopathological changes with the progress of time after formation of bite-mark, experimental bite-marks were made in female rats and histopathological examinations were performed in the given sites immediately, 5 minutes, 10 minutes, 30 minutes, I hr., 4 hrs., 8 hrs., 12 hrs., 24 hrs., and 48 hrs, after injury. Results and Summary 1. Subcutaneous loose connective tissues and fatty layers were compressed immediately after formation of bite-marks, injured epithelia showed hydropic degeneration 5 minutes later. 2. Inflammatory cells emigrated into tissues with hemorrhages in the tissues after 10 minutes, and more increased centered around the blood vessels.- These distributed most densely in the tissues, after 12 hrs., thereafter, were decreased and distributed in various groups of crowdy appearances, after 48 hrs. 3. After 10 minutes, neutrophils emigrated into tissues and disappeared gradually with an appearance of monocytes. These disappeared completely, after 24 hrs. Lymphocytes and plasma cells were see n at 48 hrs. later. 4. Adherence of mast cells to injured sites occurred immediately, and which adhered to blood vessel walls of injured sites, after 10 minutes. 8 hrs. later, degranulation in emigrated inflammatory cells showed, and these degranulation disappeared gradually with a progress of time.

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Tendon Responses Depending on Different Anatomical Locations

  • Chun, Keyoung-Jin;Robert P. Hubbard
    • Journal of Mechanical Science and Technology
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    • v.17 no.7
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    • pp.1011-1015
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    • 2003
  • The objectives of this work focus on the differences in responses of paired tendons from different anatomical locations. Tendon specimens were obtained from the hindlimbs of canines and frozen to -70$^{\circ}C$. After being thawed, specimens were mounted in the immersion bath, preloaded to 0.13N, and then subjected to 3% or 4% of the initial length at a strain rate of 5%/sec. It was found that the mechanical responses of anatomically paired tendons were nearly the same within each pair but different between pairs of tendons from different anatomical locations. Although flexor tendons had much larger cross-sectional area than the others, such as peroneus or extensor tendons, the stiffness of the flexor tendons were much lower than the others throughout their stress-strain responses. The nature and causes of these differences in the stiffness are not fully known. However, it is clear that differences in the mechanical response of tendons and other connective tissues are significant to the musculoskeletal performance.

Polygranulomatosis in the domestic chickens (닭에서 발생한 다발성 육아종증)

  • Lee, Nam-Jin;Cho, Kyoung-Oh;Kang, Mun-Il
    • Korean Journal of Veterinary Pathology
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    • v.7 no.1
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    • pp.67-69
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    • 2003
  • Three mature layer chickens from a farm in which chickens showed green diarrhea, cyanosis, lethargy, loss of appetite were pathologically examined. Grossly, multiple variable sized caseous nodules were detected in the liver, intestinal serosa and mesentery. In addition, parathypoid nodules in the liver and fibrous serositis on the several peritoneal organs and tissues were noticed. One of spleens had multiple infarction areas. Histologically caseous nodules consisted of central caseous core and peripheral epithelioid cells overlying the fibrous connective tissue. Multinucleated giant cells were scattered between the epithelioid cells and fibrous connective tissue. In these nodules Gram negative cocobacilus bacterial colonies were present, whereas Periodic Schiff reaction and Ziehl-Neelsen stain detected neither fungi nor acid fast bacteria. From these results multiple granulomas might be induced by Escherichia coli. In addition, severe Ascafdiodf and Salmonellosis were coinfected in these chickens.

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Therapeutic Effects in the RIP-treated liver Fibrosis Rat Model (천연식물추출물(RIP)이 쥐의 간섬유화 치료에 미치는 영향)

  • Cho, Soo-Hyun
    • Journal of Korean Biological Nursing Science
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    • v.8 no.2
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    • pp.41-59
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    • 2006
  • Chronic liver diseases and hepatic cancer have been reported as 10% of cause of death in Koreans. Regardless of various causes, chronic liver disease accompanies commonly hepatic fibrosis. But still the mechanism of hepatic fibrosis remains poorly understood. Using the dimethylnitrosamine(DMN)-induced hepatic fibrosis rat model, We performed to evaluate the possible therapeutic effect of RIP(extracts of Phellodendron amurense and Patrinia scabiosaefolia) and to investigate the changes in referential connective tissue proteins($TGF-{\beta}_1$, ${\alpha}$-smooth muscle actin, and vimentin) as a marker of fibrogenesis. For these purposes, liver tissues were stained with H & E, and Azan staining for estimation of developing fibrosis. In the DMN-treated rat liver tissue, fibrosis were developed forming incomplete septal fibrosis. Whereas, in the RIP-treated rat liver tissues, the fibrosis were decreased recovering to normal morphology. The expressions of $TGF-{\beta}_1$, ${\alpha}$-smooth muscle actin($\alpha-SMA$), and vimetin were increased in the DMN-treated rat liver tissues, but decreased in the various areas of RIP-treated rat liver tissues. According to these results, RIP could be a possible therapeutic agent to reduce hepatic fibrosis, and the $TGF-{\beta}_1$, ${\alpha}$-SMA, and vimentin could be possible indicative markers of hepatic fibrosis development and recovery.

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