• 한국환경과학회지
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• 제4권3호
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• pp.97-97
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• 1995

PCBs have been measured using GC-ECD, GC-MS, GC-ELCD, HPLC, TLC, NMR and Immunoassay. The analysis of PCBs using GC-ECD include the peak pattern method as none derivatization and the Perchlorination method as derivatization. This study was conducted to establish the perchlorination method with Sbcls from PCBs to decachlorinated biphenyl(DCB). The aroclor 1242 of PCBs was chlorinated and then, converted into the DCB which showed a single peak in GC-ECD chromatogram. The detection limit of DCB was 2pg. The quantification detection concentration of PCBs extracted with soxhlet was 0.5ng/g in the soil. PCBs were not detected in the suburban soil, but 174ng/g in the soil of industrial complex. Mean PCBs concentration of Shinchun stream at Kumho river and Jinchun stream at Nakdong river was calculated average 낙ngjg in 각e sediment. PCBs concentration in the sediment of Kumho river near 2-7km from conjunction with Nakdong river was average 154ng/g. PCBs concentration in the sediment of Nakdong river near conjunction with Kumho river was average 159ng/g.

• 한국환경과학회지
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• 제4권3호
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• pp.249-258
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• 1995

PCBs have been measured using GC-ECD, GC-MS, GC-ELCD, HPLC, TLC, NMR and Immunoassay. The analysis of PCBs using GC-ECD include the peak pattern method as none derivatization and the Perchlorination method as derivatization. This study was conducted to establish the perchlorination method with Sbcls from PCBs to decachlorinated biphenyl(DCB). The aroclor 1242 of PCBs was chlorinated and then, converted into the DCB which showed a single peak in GC-ECD chromatogram. The detection limit of DCB was 2pg. The quantification detection concentration of PCBs extracted with soxhlet was 0.5ng/g in the soil. PCBs were not detected in the suburban soil, but 174ng/g in the soil of industrial complex. Mean PCBs concentration of Shinchun stream at Kumho river and Jinchun stream at Nakdong river was calculated average 낙ngjg in 각e sediment. PCBs concentration in the sediment of Kumho river near 2-7km from conjunction with Nakdong river was average 154ng/g. PCBs concentration in the sediment of Nakdong river near conjunction with Kumho river was average 159ng/g.

• 대한암한의학회지
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• 제15권1호
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• pp.105-110
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• 2010

Objective: This study reports one case of polycythemia vera patient treated with oriental medicine in conjunction with conventional medicine. Methods: One patient who was diagnosed with polycythemia vera was treated using different modalities of herbs, acupuncture, and pharmacopuncture. An herbal formula, Yongdamsagan-tang was given three times a day with daily acupuncture treatment session, in addition to Soyeom and Jahageo pharmacopuncture injection which were administered three times a week. After treatment, patient's symptoms and blood test results were observed and analyzed. Results: After ten days of treatment, the patient had shown improvements in symptoms of headache, dizziness, tinnitus, and itchiness. Two months later, laboratory findings continued to be kept within the normal range and the intervals of phlebotomy therapy has extended to three months. Conclusions: This case study shows minimum evidence of safety and efficacy of oriental medicine for managing symptoms of polycythemia vera. Considering this is only a short term, single case study, further research is needed to confirm these results.

• 한국공간구조학회논문집
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• 제4권2호
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• pp.73-80
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• 2004

본 논문에서는 비선형 파라메트릭 사영필터를 이용한 2차원 트러스 구조물의 손상 검출에 대한 연구를 제시한다. 역문제의 해석은 최근 많은 관심을 끌고 있으며, 역문제 해석법으로서 필터이론을 사용한 접근법이 많은 관심을 받고 있다. 특히 칼만 필터는 신호 통신, 시스템 제어 등의 많은 분야에서 적용되어 왔으며 그 유효성이 입증되었다. 본 논문에서는 비선형 파라메트릭 사영필터를 2차원 트러스 구조물의 손상추정에 적용하고 손상된 구조물의 고유 진동수과 고유 모드를 관측 데이터로 채택하여 손상부재의 위치와 손상정도를 추정한다. 마지막으로 수치해석 예를 통하여 제안된 해석법의 유효성을 밝힌다.

• Structural Engineering and Mechanics
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• 제27권4호
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• pp.439-456
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• 2007

Reinforced concrete (RC) joint shear strength models are constructed using an experimental database in conjunction with a Bayesian parameter estimation method. The experimental database consists of RC beam-column connection test subassemblies that maintained proper confinement within the joint panel. All included test subassemblies were subjected to quasi-static cyclic lateral loading and eventually experienced joint shear failure (either in conjunction with or without yielding of beam reinforcement); subassemblies with out-of-plane members and/or eccentricity between the beam(s) and the column are not included in this study. Three types of joint shear strength models are developed. The first model considers all possible influence parameters on joint shear strength. The second model contains those parameters left after a step-wise process that systematically identifies and removes the least important parameters affecting RC joint shear strength. The third model simplifies the second model for convenient application in practical design. All three models are unbiased and show similar levels of scatter. Finally, the improved performance of the simplified model for design is identified by comparison with the current ACI 352R-02 RC joint shear strength model.

• 대한기계학회논문집
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• 제19권7호
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• pp.1691-1701
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• 1995

Two aspects of Large-Eddy Simulation(LES) are investigated in order to improve its performance. The first one is on how to determine the model coefficient in conjunction with a dynamic subgrid-scale model, and the second one is on a wall-layer model(WLM) which allows one to skip near-wall regions to save a large number of grid points otherwise required. Especially, a WLM suitable for a separated flow is considered. Firstly, an averaging technique to calculate the model coefficient of dynamic subgrid-scale modeling(DSGSM) is introduced. The technique is based on the concept of local averaging, and useful to stabilize numerical solution in conjunction with LES of complex turbulent flows using DSGSM. It is relatively simple to implement, and takes very low overhead in CPU time. It is also able to detect the region of negative model coefficient where the "backscattering" of turbulence energy occurs. Secondly, a wall-layer model based on a local turbulence intensity is considered. It locally determines wall-shear stresses depending on the local flow situations including separation, and yields better predictions in separated regions than the conventional WLM. The two techniques are tested for a turbulent obstacle flow, and show the direction of further improvements.rovements.

• 대한후두음성언어의학회지
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• 제9권1호
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• pp.71-78
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• 1998

Type Ⅰ thyuroplasty in conjunction with arytenoid adduction is one of the excellent techniques in the treatment of unilateral vocal fold paralysis. But perioperative objective evaluation of the patients is difficult. With the development of the videostroboscopy and image analysis program, we could quantify the Glottal Area Waveform(GAW) in patients with unilateral vocal fold paralysis and investigated the relationship between the glottal area and aerodynamic and acoustic parameters. Eight female patients who were performed type Ⅰ thyroplasty in conjunction with arytenoid adduction and 5 females with normal vocal function were involved in this study. Preoperative and postoperative videostroboscopy and vocal function study wire performed. GAW was analysed quantitatively with image analysis program (Kay Stroboscope Image analysis, KSIP) Peak Glottal Area(PGA), Baseline Offset(BO), and Closing Phase(CP) were increased in patients with unilateral vocal fold paralysis and they were reduced after the operation. Mean flow Rate (MFR) was well correlated with the PGA in normal control group and unilateral vocal fold paralysis patients. Noise to harmonic ratio(NHR) was correlated with PGA only in preoperative unilateral vocal fold paralysis patients. In conclusion quantitative measurement of the GAW is useful method in evaluation of unilateral vocal f31d paralysis patients.

• Toxicological Research
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• 제32권1호
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• pp.15-20
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• 2016

Physiologically based pharmacokinetic (PBPK) modeling can provide an effective way to utilize in vitro and in silico based information in modern risk assessment for children and other potentially sensitive populations. In this review, we describe the process of in vitro to in vivo extrapolation (IVIVE) to develop PBPK models for a chemical in different ages in order to predict the target tissue exposure at the age of concern in humans. We present our on-going studies on pyrethroids as a proof of concept to guide the readers through the IVIVE steps using the metabolism data collected either from age-specific liver donors or expressed enzymes in conjunction with enzyme ontogeny information to provide age-appropriate metabolism parameters in the PBPK model in the rat and human, respectively. The approach we present here is readily applicable to not just to other pyrethroids, but also to other environmental chemicals and drugs. Establishment of an in vitro and in silico-based evaluation strategy in conjunction with relevant exposure information in humans is of great importance in risk assessment for potentially vulnerable populations like early ages where the necessary information for decision making is limited.

• International Journal of Aeronautical and Space Sciences
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• 제12권4호
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• pp.318-330
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• 2011

This paper investigates the convergence characteristics of the modified artificial compressibility method proposed by Turkel. In particular, a focus is mode on the convergence characteristics due to variation of the preconditioning factor (${\alpha}_u$) and the artificial compressibility (${\beta}$) in conjunction with an upwind method. For the investigations, a code using the modified artificial compressibility is developed. The code solves the axisymmetric incompressible Reynolds averaged Navier-Stokes equations. The cell-centered finite volume method is used in conjunction with Roe's approximate Riemann solver for the inviscid flux, and the central difference discretization is used for the viscous flux. Time marching is accomplished by the approximated factorization-alternate direction implicit method. In addition, Menter's k-${\omega}$ shear stress transport turbulence model is adopted for analysis of turbulent flows. Inviscid, laminar, and turbulent flows are solved to investigate the accuracy of solutions and convergence behavior in the modified artificial compressibility method. The possible reason for loss of robustness of the modified artificial compressibility method with ${\alpha}_u$ >1.0 is given.

• 자원환경지질
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• 제26권2호
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• pp.155-166
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• 1993

Gold contents with major and trace elements have been determined in 67 fresh igneous and altered wall rocks in the acid-sulfate alteration zone of the Ogmaesan-Seongsan pyrophyllite deposits in the Haenam area of the south-western part of Korean peninsula. The results are as follows; (1) Li contents have a tendency to show high value in dickite and altered rocks with dickite, while As, Mo and Sb contents have tendencies to show high values in alunite vein and silicified zone. F contents are higher in the altered rocks compared to fresh rocks. (2) Gold contents are enriched in alunite vein and silicified zone of the Seongsan deposit, but depleted in dickite and altered rock with dickite. Gold contents are especially concentrated in fault or conjunction area of two faults. (3) Gold contents are higher values in the mineral assemblages of alunite-quartz-pyrite and alteration zone of the Seongsan deposit among the studied deposits. (4) Gold contents in samples of silicified zones tend to show positive correlations with Ag, As, Co, Hg, Sb and V content, but negative correlations with Y and Zr contents, while on the other gold contents of silicified tuffs tend to show positive correlations with Hg and Sb contents. Therefore it is important to survey alunite vein and silicified zone at the conjunction of faults, and to analyze pathfinder elements such as Ag, As, Hg and Sb for geological and geochemical exploration of gold in the studied deposits.