• The Journal of Internal Korean Medicine
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• v.38 no.1
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• pp.72-80
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• 2017

Objective: The purpose of this study is to report the case of a patient with recurring non-small cell lung carcinoma (NSCLC) taking Samchilchoongcho-Jung with Afatinib. Methods: An NSCLC patient diagnosed with multiple bone and pulmonary metastasis was taking Afatinib (20 mg/day) and suffering from stomatitis caused by the Afatinib. The patient was treated with Samchilchoongcho-Jung (1,500 mg/ day) for 3 months. The tumor size was measured with computed tomography, and laboratory findings, including tumor markers (CEA, Cyfra 21-1), were also followed up. Stomatitis was measured by a numeric rating scale, and adverse events were evaluated using the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE), version 4.0. Results: After combined treatment, stable disease was shown on computed tomography. The tumor marker levels of CEA and Cyfra 21-1 were decreased, and the stomatitis significantly improved. NCI-CTCAE 4.0 showed no adverse events. Conclusion: This case study suggests that Samchilchoongcho-Jung may have a synergic effect, in conjunction with Afatinib, on the treatment of patients with recurring NSCLC.

• Smart Structures and Systems
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• v.13 no.6
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• pp.1015-1039
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• 2014

The widening project on Freeway No.1 in Taiwan has a total length of roughly 14 kilometers, and includes three special bridges, namely a 216 m long-span bridge crossing the original freeway, an F-bent double decked bridge in a co-constructed section, and a steel and prestressed concrete composite bridge. This study employed in-situ monitoring in conjunction with numerical modeling to establish a real-time monitoring system for the three bridges. In order to determine the initial static and dynamic behavior of the real bridges, forced vibration experiments, in-situ static load experiments, and dynamic load experiments were first carried out on the newly-constructed bridges before they went into use. Structural models of the bridges were then established using the finite element method, and in-situ vehicle load weight, arrangement, and speed were taken into consideration when performing comparisons employing data obtained from experimental measurements. The results showed consistency between the analytical simulations and experimental data. After determining a bridge's initial state, the proposed in-situ monitoring system, which is employed in conjunction with the established finite element model, can be utilized to assess the safety of a bridge's members, providing useful reference information to bridge management agencies.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.35 no.5
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• pp.346-352
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• 2009

There have been reports of successful bone formation with sinus floor elevation by simply elevating the maxillary sinus membrane and filling the sinus cavity below the lifted sinus membrane with a blood clot. But, in a review of the current literature, we found no animal study that substantiated blood clot's ability in this respect. The aim of this study was to investigate the effect of the method of maxillary sinus floor augmentation using the patient's own venous blood in conjunction with a sinus membrane elevation procedure. An implant was placed bilaterally in the maxillary sinus of six adult mongrel dogs so that it protruded 8 mm into the maxillary sinus after sinus membrane elevation. On one side of the maxillary sinus, the resultant space between the membrane and the sinus floor was filled with autologous venous blood retrieved from the dog. On the opposite side, the maxillary sinus was left untreated as a control. The implants were left in place for six months. The mean height of the newly formed bone in the sinus was 3.7 mm on the side without venous blood and 3.5 mm on the side with venous blood (p>0.05). There was no difference between the two sides regarding new bone height in the sinus. Our results indicate that filling the space between the lifted sinus membrane and the sinus floor with venous blood has no effect on bone formation around implants placed in the maxillary sinus cavity.

• Journal of Periodontal and Implant Science
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• v.25 no.3
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• pp.623-634
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• 1995

Periodontitis is characterized by gingival inflammation and results in periodontal pocket formation with loss of the supporting alveolar bone and connective tissue around the teeth. Therapeutic modalities should therefore aim not only at eliminating the gingival inflammatory process and preventing the progression of periodontal disease but also at reestablishing and regenerating the periodontal tissue previously lost to the disease. To achieve periodontal regeneration, progenitor cells must migrate to the denuded root surface, attach to it, proliferate and mature into an organized and functional fibrous attachment apparatus. Likewise, progenitor bone cells must also migrate, proliferate, and mature in conjunction with the regenerating periodontal ligament. Significant advances have been made during the last decade in understanding the factors controlling the migration, attachment and proliferation of cells. A group of naturally occuring molecules known as polypeptide growth factors in conjunction with certain matrix proteins are key regulators of these biological events. Of these, the fibroblast growth factor(FGF), platelet-derived growth factor(PDGF) , insulin like growth factor(CIGFs), transforming growth factor(TGFs), epidermal growth factor(EGF) and bone morphogenetic growth factor(BMPs) apper to have an important role in periodontal wound healing. The purpose of this study was to determine the effects of BMP on periodontal ligament cells. Human periodontal ligament cells were cultured from extracted tooth for non-periodontal reason. Cultured periodontal ligament cells were treated with BMP. Cellular activities were determined by MTT(3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) assay and ALP(alkaline phosphatase) activity. The results were as follows ; Regardless of cultured time, cellular activities were stimulated by BMP. Also, BMP greatly increased alkaline phosphatase(ALP) in periodontal ligament cells. These results suggest that BMP not only have no cytotoxic effect on periodontal ligament cells, but also have osteogenic stimulatory effect on periodontal ligament cells.

• Journal of the Korean Society of Physical Medicine
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• v.8 no.1
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• pp.137-145
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• 2013

PURPOSE: The purpose of this study is to examine assessment of test-retest reliability for 13 items of pediatric balance scales, then the intrarater reliability among the raters. METHODS: Study participants included 6 children with spastic cerebral palsy who could walk. Raters were consist of seventy-four, 2nd year physical therapy major students. The children's ability to achieve physical balance was wideotaped for PBS items. The raters watched the tapes and evlauated each child twice. Test-retest reliability was analyzed using the Spearman correlation, and interrater reliability was analyzed using the Kendall's coefficient of concordance for ranks. RESULTS: The total PBS scores averaged 49.22 and 50.06 for first and second tests. Test-retest reliability of PBS individual items were between low and high. The low itmes were 3 items, and high were 4 itmes. Interrater reliability were low agreement. CONCLUSION: Based on the study, the pediatric balance scale is an effective evaluating tool for measuring functional balance of school age child. However, the agreement of students or beginner's interpretation is necessary in conjunction to this study results. On top of that, it is important to provide detailed explanation and repetitive training, which improves the analysis reliability. Also, each category subscores level for the pediatric balance scale must be examined carefully in conjunction to performing test, only after improving match quality via preceding practice.

• Journal of Preventive Medicine and Public Health
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• v.10 no.1
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• pp.52-58
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• 1977

By evaluating the health status by Cornell Medical Index in conjunction with their academic grade, we attempted to find out whether any health condition may affect on their academic carrier. CMI health questionnaire was filled out by student and matched with one's own academic score if the previous year. Academic score was classified into 5 grades: excellent, very good, good, fair and poor. Difference in number of questions between sections was corrected by standard score method with means of 50 and standard deviation of 10. Differences in number of 'yes' answers between sections and between groups of students in each grade were statistically tested by two-way variance analysis method. On the other hand, influence of neuropsychiatric factors (section M-R) on the academic carrier was analyzed by $X^2-test$ with Fukamachi's classification. The following were the results obtained in this study: 1) Number of 'yes' answers in sections related to mood and feeling patterns (sections M-R) were appeared to be influential to academic carrier in male students, but not in female students. 2) Generally speaking, in groups of higher academic grade, number of 'yes' answers in each section was on an averege 50 or less, and in groups of lower academic grade, the number was 50 or more depending on sections. 3) Number of 'yes' answers between sections and between groups in each academic grade were significantly different both in male and female college students. 4) It was noteworthy that data obtained from CMI questionnaire might be variable subjectively by examinees with some factors at the time of administration.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.8
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• pp.1965-1972
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• 2015

The Missile Flight Test Launch Control System is to operate in conjunction with the Fire Control System during flight test to guided weapons. Also, this is a system for the test control and situation monitoring depending on the type of guided weapons and testing purposes. Message structure, communication protocols, such as data types for interworking with the fire control system and the Missile Flight Test Launch Control System are defined in the Launch Control ICD(Interface Control Document). ICD are composed differently of each guided weapons system and each test object. Previously, in order to interwork with the Fire Control System, the interlocking software was developed, which had a variety of problems. Therefore, we developed a new parsing algorithm in order to recognize the variety of Launch Control ICD and verified that the algorithm operates normally by checking transmitting and receiving various message in conjunction with the fire control system.

• Progress in Medical Physics
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• v.13 no.2
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• pp.62-68
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• 2002

A muiltileaf collimator (MLC) is used as a replacement for conventional blocks. The MLC, however may not be appropriate for a fine field shaping. For the fine field shaping, conventional block can be added under the MLC. But it may significantly affect on the dosimetric characteristics such as surface dose of skin, buildup region and percent depth doses. We performed the study to evaluate the surface dose and the maximum depth dose using MLC conjunction with conventional blocks for various field sizes and energies. We confirmed the surface dose was increased by using the additional conventional block under the MLC ranging from 10 to 35.6％ according to various field sizes and radiation beam energies. The surface dose was effectively reduced by application of 2 or 3 m thickness of lead plate as electron filter.

• The Journal of Korean Academy of Prosthodontics
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• v.42 no.1
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• pp.30-40
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• 2004

Purpose : The purpose of this study was aimed to compare the shear bond strength on dentin of three dentin bonding agents and two resin cements used in conjunction with self-cured composite resin core material. Material and method : Control group and six experimental groups were divided for this study. Control group was designated as specimens bonded with Tenure$ A&B^{(R)}$. Experimental groups were as follows : PB-BL group : specimens bonded with Prime&Bond $NT^{(R)}$, $BondLink^{(R)}$ SB-BL group : specimens bonded with $^{(R)}$, BondLink$SingleBond^{(R)}$ PB group : specimens bonded with Prime&Bond $NT^{(R)}$ SB group : specimens bonded with $SingleBond^{(R)}$ PF group : specimens bonded with $Panavia-F^{(R)}$ BI group specimens bonded with Bistite $II^{(R)}$ All specimens were stored in $37^{\circ}C$ distilled water for 24 hours, followed by the shear bond strength was tested by universal testing machine. The data was analysed statistically by Mann-Whitney test. Results : 1. For Prime&Bond $NT^{(R)}$ and $SingleBonde^{(R)}$, the shear bond strength was 0.24 MPa and 7.19 MPa each by each, while Tenure $A&B^{(R)}$ group control was measured at 13.93 MPa (p<0.05). Especially for Prime&Bond $NT^{(R)}$ it did not get conjunction with dentin. 2. For Prime&Bond $NT^{(R)}$ and $SingleBond^{(R)}$ using $BondLink^{(R)}$, there was no significant difference as a result of 11.73 MPa and 14.00 MPa each by each (p<0.05). 3. For $Panavia-F^{(R)}$ and Bistite $II^{(R)}$, they showed the highest shear bond strength as measured by 18.24 MPa and 16.09 MPa each (p<0.05).

• Journal of Korean Society on Water Environment
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• v.30 no.2
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• pp.138-147
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• 2014

In order to determine the best operating rules for the Nakdong River, three cases were applied to analyze the simulated results of water supply capacity by HEC-ResSim model. This study discussed to present the best operating rules for conjunctive operating of existing the dams and new constructed the weirs through system network. The system network was constructed considering the water supply, the river environment and the operating facility. The water supply capacities are separately evaluated for each case applying the best rules. It is case1 that the dams are operated individually, case2 that the dams are operated in conjunction with the others dams, and case3 that dams and weirs are operated in conjunction with the others dams-weirs. Comparing the cases, case 3 has shown the best water supply capacity of the Nakdong River.