• Journal of the Korean Data and Information Science Society
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• v.25 no.1
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• pp.211-218
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• 2014

Qu et. al. (2000) proposed the quadratic inference functions (QIF) method to marginal model analysis of longitudinal data to improve the generalized estimating equations (GEE). It yields a substantial improvement in efficiency for the estimators of regression parameters when the working correlation is misspecified. But for the longitudinal data with time-dependent covariates, when the implicit full covariates conditional mean (FCCM) assumption is violated, the QIF can not provide more consistent and efficient estimator than GEE (Cho and Dashnyam, 2013). Lai and Small (2007) divided time-dependent covariates into three types and proposed generalized method of moment (GMM) for longitudinal data with time-dependent covariates. They showed that their GMM type II and GMM moment selection methods can be more ecient than GEE with independence working correlation (GEE-ind) in the case of type II time-dependent covariates. We develop upgraded QIF method for type II time-dependent covariates. We show that this upgraded QIF method can provide substantial gains in efficiency over QIF and GEE-ind in the case of type II time-dependent covariates.

• Journal of the Korean Data and Information Science Society
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• v.24 no.3
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• pp.651-658
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• 2013

For the marginal model and generalized estimating equations (GEE) method there is important full covariates conditional mean (FCCM) assumption which is pointed out by Pepe and Anderson (1994). With longitudinal data with time-varying stochastic covariates, this assumption may not necessarily hold. If this assumption is violated, the biased estimates of regression coefficients may result. But if a diagonal working correlation matrix is used, irrespective of whether the assumption is violated, the resulting estimates are (nearly) unbiased (Pan et al., 2000).The quadratic inference functions (QIF) method proposed by Qu et al. (2000) is the method based on generalized method of moment (GMM) using GEE. The QIF yields a substantial improvement in efficiency for the estimator of ${\beta}$ when the working correlation is misspecified, and equal efficiency to the GEE when the working correlation is correct (Qu et al., 2000).In this paper, we interest in whether the QIF can improve the results of the GEE method in the case of FCCM is violated. We show that the QIF with exchangeable and AR(1) working correlation matrix cannot be consistent and asymptotically normal in this case. Also it may not be efficient than GEE with independence working correlation. Our simulation studies verify the result.

• Journal of KIISE:Software and Applications
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• v.33 no.10
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• pp.877-885
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• 2006

Recently it is proposed that the Bayesian networks used as conversational agent for topic inference is useful but the Bayesian networks require much time to model, and the Bayesian networks also have to be modified when the scripts, the database for conversation, are added or modified and this hinders the scalability of the agent. This paper presents a method to improve the scalability of the agent by constructing the Bayesian network from scripts automatically. The proposed method is to model the structure of Bayesian networks hierarchically and to utilize Noisy-OR gate to form the conditional probability distribution table (CPT). Experimental results with ten subjects confirm the usefulness of the proposed method.

• Journal of the Korean Data and Information Science Society
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• v.25 no.5
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• pp.1039-1055
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• 2014

The distribution of a test statistic under a null hypothesis depends on the unknown distribution of the data and thus is unknown as well. Conditional tests replace the unknown null distribution by the conditional null distribution, that is, the distribution of the test statistic given the observed data. This approach is known as permutation tests and was developed by Fisher (Fisher, 1935). Theoretical framework for permutation tests was given by Strasser and Weber(1999). The coin package developed by Hothon et al. (2006, 2008) implements a unified approach for conditional inference via the generic independence test. Because convenient functions for the most prominent problems are available, users will not have to use the extremely flexible procedure. In this article we briefly review the underlying theory from Strasser and Weber (1999) and explain how to transform the data to perform the generic function independence test. Finally it was illustrated with a few real data sets.

• Journal of Bone Metabolism
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• v.25 no.4
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• pp.251-266
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• 2018

Background: The causal networks among genes that are commonly expressed in osteoblasts and during bone metastasis (BM) of breast cancer (BC) are not well understood. Here, we developed a machine learning method to obtain a plausible causal network of genes that are commonly expressed during BM and in osteoblasts in BC. Methods: We selected BC genes that are commonly expressed during BM and in osteoblasts from the Gene Expression Omnibus database. Bayesian Network Inference with Java Objects (Banjo) was used to obtain the Bayesian network. Genes registered as BC related genes were included as candidate genes in the implementation of Banjo. Next, we obtained the Bayesian structure and assessed the prediction rate for BM, conditional independence among nodes, and causality among nodes. Furthermore, we reported the maximum relative risks (RRs) of combined gene expression of the genes in the model. Results: We mechanistically identified 33 significantly related and plausibly involved genes in the development of BC BM. Further model evaluations showed that 16 genes were enough for a model to be statistically significant in terms of maximum likelihood of the causal Bayesian networks (CBNs) and for correct prediction of BM of BC. Maximum RRs of combined gene expression patterns showed that the expression levels of UBIAD1, HEBP1, BTNL8, TSPO, PSAT1, and ZFP36L2 significantly affected development of BM from BC. Conclusions: The CBN structure can be used as a reasonable inference network for accurately predicting BM in BC.

• The Korean Journal of Applied Statistics
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• v.35 no.2
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• pp.311-325
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• 2022

For count responses, the situation of excess zeros often occurs in various research fields. Zero-inflated model is a common choice for modeling such count data. Bayesian inference for the zero-inflated model has long been recognized as a hard problem because the form of conditional posterior distribution is not in closed form. Recently, however, Pillow and Scott (2012) and Polson et al. (2013) proposed a Pólya-Gamma data-augmentation strategy for logistic and negative binomial models, facilitating Bayesian inference for the zero-inflated model. We apply Bayesian zero-inflated negative binomial regression model to longitudinal pharmaceutical data which have been previously analyzed by Min and Agresti (2005). To facilitate posterior sampling for longitudinal zero-inflated model, we use the Pólya-Gamma data-augmentation strategy.

• Communications for Statistical Applications and Methods
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• v.7 no.2
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• pp.533-540
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• 2000

The problem of information related to I poission experiments, each having a distinct failure rate $\theta$i I=1,2,…,I, is considered. Instead of using a standard exchangeable prior for $\theta$=($\theta$1,$\theta$2,…,$\theta$I), we consider a partition of the experiments and take the $\theta$i's belonging to the same partition subgroup to be exchangeable and the $\theta$i's belonging to distinct subgroups to be independent. And we perform Gibbs sampling approach for Bayesian inference on $\theta$ conditional on a partition. Numerical study using real data is provided.

• Journal of the Korean Statistical Society
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• v.24 no.1
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• pp.197-218
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• 1995

We first consider the random censorship model of survival analysis. Efron (1981) introduced two equivalent bootstrap methods for censored data. We propose a new bootstrap scheme, called Method 3, that acts conditionally on the censoring pattern when making inference about aspects of the unknown life-time distribution F. This article contains (a) a motivation for this refined bootstrap scheme ; (b) a proof that the bootstrapped Kaplan-Meier estimatro fo F formed by Method 3 has the same limiting distribution as the one by Efron's approach ; (c) description of and report on simulation studies assessing the small-sample performance of the Method 3 ; (d) an illustration on some Danish data. We also consider the model in which the survival times are censered by death times due to other caused and also by known fixed constants, and propose an appropriate bootstrap method for that model. This bootstrap method is a readily modified version of the Method 3.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.1524-1529
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• 2005

Particle filter is a kind of conditional density propagation model. Its similar characteristics to both selection and mutation operator of evolutionary strategy (ES) due to its Bayesian inference rule structure, shows better performance than any other tracking algorithms. When a new object is entering the region of interest, particle filter sets which have been swarming around the existing objects have to move and track the new one instantaneously. Moreover, there is another problem that it could not track multiple objects well if they were moving away from each other after having been overlapped. To resolve reinitialization problem, we use competitive-AVQ algorithm of neural network. And we regard interfarme difference (IFD) of background images as potential field and give priority to the particles according to this IFD to track multiple objects independently. In this paper, we showed that the possibility of real-time object tracking as intelligent interfaces by simulating the deformable contour particle filters.

• Journal of the Korean Data and Information Science Society
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• v.12 no.1
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• pp.1-9
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• 2001

In this paper, the problem of information related to I binomial experiments, each having a distinct probability of success ${\theta}_i$, i = 1,2, $\cdots$, I, is considered. Instead of using a standard exchangeable prior for ${\theta}\;=\;({\theta}_1,\;{\theta}_2,\;{\cdots},\;{\theta}_I)$, we con-sider a partition of the experiments and take the ${\theta}_i$'s belonging to the same partition subset to be exchangeable and the ${\theta}_i$'s belonging to distinct subsets to be independent. And we perform Gibbs sampler approach for Bayesian inference on $\theta$ conditional on a partition. Also we illustrate the methodology with a real data.