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Two Cases of Primary Localized Amyloidosis of Larynx (원발성 국소 후두아밀로이드증 2례)

  • 김형태;조승호;전범조;김민식
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.9 no.2
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    • pp.147-151
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    • 1998
  • Primary localized laryngeal amyloidosis is an uncommon disorder of unknown cause that occurs in the absence of systemic amyloidosis or associated disease. There is a risk of either missing concomitant systemic amyloidosis or exhaustively investigating for this when it is not present through failure to appreciate the nature of the disease. We present 2 cases of primary localized laryngeal amyloidosis in supraglottic region. Biopsy of the mass of patients revealed findings consistent with amyloidosis, which were Congo red reaction with a apple green birefringence in polarized light fluorescence microscopy. An extensive workup for systemic amyloidosis was negative. All of two cases were treated by vaporization via $CO_2$ LASER using "Swiftlase Flshscan" for creating a wide, shallow char-free treatment site by precisely controlling ablation depth without causing residual thermal damage to tissue. The postoperative recovery of all cases was uneventful with good vocal quality and no aspiration. At the present time, the patients have no evidence of disease, recurrence and complication.

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An Aerodynamic Noise Reduction Design at Inter-coach Space of High Speed Trains Based on Biomimetic Analogy

  • Han, Jae-Hyun;Kim, Jung-Soo
    • International Journal of Railway
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    • v.4 no.3
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    • pp.74-79
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    • 2011
  • Recent years have witnessed speed up of moving vehicles such as high-speed of trains. Increase in speed entails concomitant increase in turbulent air flow which contributes toward increased aerodynamic noise. The proposed method for aerodynamic noise reduction is based on a biomimetic design of owl feather. The five morphological parameters of the owl feather are extracted from close observation, and simulation cases are constructed by applying design of experiments methodology. Swirling strength for each case is obtained through steady-state CFD analysis, and key morphological parameters that affect the turbulence are identified. Large eddy simulations (LES) are then performed on selected cases to predict the air turbulence. Different cases show varying vortex distributions which are expected to lead to varying aerodynamic noise levels.

Traumatic Spinal Subdural Hematoma Accompanying intracranial hematoma: Spontaneous Resolution after Pumbar Puncture (외상성 구개강내 출혈과 동반된 척추경막하 출혈; 요추 전자부 자연흡수)

  • Lee, Won Tae;Kim, Seok Won
    • Journal of Trauma and Injury
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    • v.19 no.1
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    • pp.93-96
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    • 2006
  • A traumatic spinal subdural hematoma is a rare condition, and only nine cases have been reported until now. We report a rare case of concomitant intracranial hemorrhage and spinal subdural hematoma with a review of the literature. A 45-year-old man was referred to our institute after being stroke by a car. He complained of nausea, headache, back pain, and bilateral sciatica. Brain computed tomography and lumbar spine magnetic resonance images revealed both an intracerbral hemorrhage and a subdural hematoma in the L4 to S1 level. After performing a lumbar spinal puncture and draining the hemorrhagic cerebrospinal fluid (CSF), the intracranial and spinal hematomas were resolved completely without any neruologic deficits.

Short Form Versions of MacArthur-Bates Communicative Development Inventories - Korean (M-B CDI-K) (M-B CDI - Korean 축약판 개발)

  • Pae, So-Yeong;Kwak, Keum-Joo;Kim, Mi-Bae;Lee, Hyun-Suk;Jung, Kyung-Hee
    • Speech Sciences
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    • v.15 no.2
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    • pp.119-129
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    • 2008
  • The purpose of this study were to develop short form versions of MacArthur-Bates Communicative Development Inventories - Korean and to discuss clinical implications. Two short versions were developed: one for $9\sim17$ month-olds(including 69 words and 17 object manipulation skills) and the other for $18\sim35$ month-olds (including 128 words and 5 grammatical items). Short versions seemed to be representative of full versions and showed developmental validity. Short versions showed concomitant validity with SELSI which is a standardized test for Korean children under 37 month-olds. Norm tables for words and criteria for object manipulation and grammaticality are also provided. M-B CDI-K short versions could be used as a preliminary screening tool to identify Korean children with language impairment economically and efficiently. Cautions using short versions of M-B CDI-K are discussed.

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MOMENT-OF-FLUID METHOD FOR FREE SURFACE FLOW SIMULATION USING UNSTRUCTURED MESHES (비정렬 격자상에서 Moment-of-Fluid 방법을 이용한 자유표면유동계산)

  • Ahn, H.T.
    • 한국전산유체공학회:학술대회논문집
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    • 2011.05a
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    • pp.65-67
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    • 2011
  • The moment-of-fluid (MOF) method is a new volume-tracking method that accurately treats evolving material interfaces. The MOF method uses moment data, namely the material volume fraction, as well as the centroid, for a more accurate representation of the material configuration, interfaces and concomitant volume advection. In this paper, unstructured mesh extension of the MOF method is to be presented. The MOF method is coupled with a stabilized finite element incompressible Navier-Stokes solver for two materials. The effectiveness of the MOF method is demonstrated with a free-surface dam-break problem.

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Indication and Pre-operative Planning of Meniscal Allograft Transplantation (연골판 이식술의 적응증과 수술 전 계획)

  • Kim, Tae-Hyung;Choi, Nam-Hong
    • Journal of the Korean Arthroscopy Society
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    • v.15 no.1
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    • pp.32-35
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    • 2011
  • Meniscal allograft transplantation is considered to restore important functions of the meniscus after total and subtotal meniscectomy. There are patients who need meniscal allograft transplantation have concomitant lesions; chronic anterior cruciate ligament tear, chondral defect, and malalignment of the knee. Therefore proper selection of the patients and thorough preparation of operative procedure are imperative to get satisfactory results.

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The Clinical Report about the Stagnation Syndrome of Qi (기울증) Treated with Gyogam-dan plus Ganggi-tang (기울증을 교감단합항기탕으로 치료한 임상 1예)

  • 이진헌;조성은;우영민;김용호
    • The Journal of Korean Medicine
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    • v.22 no.4
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    • pp.171-176
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    • 2001
  • The Stagnation Syndrome of Qi is the depressed and suppressed mental state caused by anxiety, unaccomplished desire, maintained thought, and emotional problems, resulting in a concomitant physiological somatic dysfunction. Although blood test, urine test, EKG, and gastric endoscopy showed normal finding. a patient complained of a group of symptoms, so we considered it as an unidentified clinical syndrome. This syndrome could be interpreted as the disconnection of Fire (Heart) and Water (Kidney) in Oriental medicine, and treated with the therapeutic method of 'Ascending Water-Descending Fire'. After the application of Gyogam-dan and Ganggi-tang for 18 days, symptoms and signs improved.

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Toxic epidermal necrolysis induced by lamotrigine treatment in a child

  • Yi, Youngsuk;Lee, Jeong Ho;Suh, Eun Sook
    • Clinical and Experimental Pediatrics
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    • v.57 no.3
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    • pp.153-156
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    • 2014
  • Toxic epidermal necrolysis is an unpredictable and severe adverse drug reaction. In toxic epidermal necrolysis, epidermal damage appears to result from keratinocyte apoptosis. This condition is triggered by many factors, principally drugs such as antiepileptic medications, antibiotics (particularly sulfonamide), nonsteroidal anti-inflammatory drugs, allopurinol, and nevirapine. Lamotrigine has been reported potentially cause serious cutaneous reactions, and concomitant use of valproic acid with lamotrigine significantly increases this risk. We describe a case of an 11-year-old girl with tic and major depressive disorders who developed toxic epidermal necrolysis after treatment with lamotrigine, and who was diagnosed both clinically and pathologically. Children are more susceptible to lamotrigine-induced rash than adults, and risk of serious rash can be lessened by strict adherence to dosing guidelines. Unfortunately, in our case, the patient was administered a higher dose than the required regimen. Therefore, clinicians should strictly adhere to the dose regimen when using lamotrigine, especially in children.

Studies of High-Ozone Episodes in the Greater Seoul Area between 1990 and 1997 (1990~1997 기간 중 서울.수도권 지역의 고농도 오존 사례 연구)

  • 김영성;오현선
    • Journal of Korean Society for Atmospheric Environment
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    • v.15 no.3
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    • pp.267-280
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    • 1999
  • To investigate the characteristics of high-ozone occurrences in the Greater Seoul Area(GSA), three high-ozone episodes were selected, for which the ozone warning for concentration above 120 ppb might be issued. The selection was on the basis of morning wind directions and speeds, and daily maximum ozone concentrations measured between 1990 and 1997. The episodes chosen to meet selection criteria were seven days in July 1992, nine days in July 1994, and three days in August 1994, as respectively characterized by southwesterly, easterly, and calm winds in the morning. However, more than 80% of high-ozone days in the GSA were associated with calm winds and the concomitant accumulation of local emission in the morning, rather than being due to transport of ozone or its precursors. This is believed to be the primary reason why ozone concentrations in the GSA varied in a completely different manner even between adjacent monitoring stations. Several premises for initiating research studies for resolving these local variations of ozone concentrations in the GSA are also discussed.

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Characteristics of Nitrobenzene Degradation by Mycobacterium chelonae Strain NB01

  • Oh, Young-Sook;Lee, Youn-Hee;Lee, Jung-Hyun;Choi, Sung-Chan
    • Journal of Microbiology and Biotechnology
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    • v.13 no.2
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    • pp.309-312
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    • 2003
  • A bacterial strain NB01, isolated from wastewater, was found to utilize nitrobenzene (NB) as the sole source of nitrogen, carbon, and energy. The strain was classified as a member of a high G+C Gram-positive group and identified as Mycobacterium chelonae based on an analysis of its 16S rRNA gene sequence. The strain grew on NB with a concomitant release of about 63% of the total available nitrogen as ammonia, suggesting a reductive degradation mechanism. The optimal pH and temperature for degradation were PH 7.0-8.0 and $30^{\circ}C$, respectively. The cell growth was retarded at NB concentrations above 1.8 mM. The degradation of NB followed Michaelis-Menten kinetics within the tolerance range, and the $K_m$ and maximum specific removal rate for NB were 0.33 mM and $11.04\;h^{-1}$, respectively.