• Title/Summary/Keyword: concepts understanding

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Mechanisms of radiation-induced normal tissue toxicity and implications for future clinical trials

  • Kim, Jae Ho;Jenrow, Kenneth A.;Brown, Stephen L.
    • Radiation Oncology Journal
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    • v.32 no.3
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    • pp.103-115
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    • 2014
  • To summarize current knowledge regarding mechanisms of radiation-induced normal tissue injury and medical countermeasures available to reduce its severity. Advances in radiation delivery using megavoltage and intensity-modulated radiation therapy have permitted delivery of higher doses of radiation to well-defined tumor target tissues. Injury to critical normal tissues and organs, however, poses substantial risks in the curative treatment of cancers, especially when radiation is administered in combination with chemotherapy. The principal pathogenesis is initiated by depletion of tissue stem cells and progenitor cells and damage to vascular endothelial microvessels. Emerging concepts of radiation-induced normal tissue toxicity suggest that the recovery and repopulation of stromal stem cells remain chronically impaired by long-lived free radicals, reactive oxygen species, and pro-inflammatory cytokines/chemokines resulting in progressive damage after radiation exposure. Better understanding the mechanisms mediating interactions among excessive generation of reactive oxygen species, production of pro-inflammatory cytokines and activated macrophages, and role of bone marrow-derived progenitor and stem cells may provide novel insight on the pathogenesis of radiation-induced injury of tissues. Further understanding the molecular signaling pathways of cytokines and chemokines would reveal novel targets for protecting or mitigating radiation injury of tissues and organs.

Use and Misuse of Statistical Methods in the Journal of Korean Academy of Nursing Administration (간호행정학회지 게재논문의 통계학적 방법 사용과 오류)

  • Song, Kijun
    • Journal of Korean Academy of Nursing Administration
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    • v.19 no.1
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    • pp.146-154
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    • 2013
  • Purpose: To do nursing research effectively requires an understanding of fundamental principles of statistical methods. In this article, some key statistical methods which are commonly used in nursing research are identified and summarized. Methods: Ninety-two original articles from the Journal of Korean Academy of Nursing Administration were reviewed. Statistical methods were classified and summarized for usage in research and occurrence of common errors. Results: Among the original articles reviewed, 58 statistical usages contained errors. Most errors were found in linear regression analysis, Pearson correlation analysis, and chi-square test. From the detection of statistical errors in usage, suggestions for appropriate statistical methods were made. Conclusion: In order to improve validity of original articles in the Journal of Korean Academy of Nursing Administration, clearly stated statistical usage and close editorial attention to statistical methods are needed. Understanding statistical methods is part of the process that researchers must use to determine both quality and usefulness of the research. Research findings will be used to guide nursing practice and reduce uncertainty in decision making. However, to understand how to interpret research results, it is important to be able to understand basic statistical concepts. Researchers should also choose statistical methods that match their purposes.

Visual simulator for supporting to learn efficiently on dynamic programming (동적 프로그래밍에 대한 효율적인 학습을 지원하는 시각화 시뮬레이터)

  • Jung, Soon-Young;Kwon, Han-Sook
    • The Journal of Korean Association of Computer Education
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    • v.11 no.4
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    • pp.23-36
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    • 2008
  • It's known by recent surveys that many students have difficulty in understanding the concepts of programming algorithms, and don't feel interested in learning them. Dynamic programming, one of the most important and widely-used algorithms in computer science, is especially feared by students and unlike other algorithms, it also requires understanding of the process of problem solving and storage space design as well as basic principles of the algorithm. And so it has not been properly covered in classes. In this paper, we developed a visual simulator to solve the above problems in learning dynamic programming. This learning simulator is designed for students to run the algorithms themselves and learn how it works by visualizing each step of dynamic programming and corresponding states of storage space.

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Historic Preservation towards a Critical Regionalism of Gil-ryong Park's Buildings: The Hwashin Department Store and the No-soo Park house

  • Seo, Myengsoo
    • Architectural research
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    • v.19 no.1
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    • pp.21-26
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    • 2017
  • This research examines the historic preservation of Korean modern architecture by applying Kenneth Frampton(1930-)'s concept of critical regionalism. It explores the representative Korean modern architect Gil-ryong Park (1898-1943) and two of his buildings: the Hwashin Department Store (1935) and the No-soo Park house (1937-1938). The former was in the hot spot on the preservation. There were plans to preserve this building but that it ended up being demolished in 1987. The latter building, however, has been preserved and is currently being used as a museum. These two Korean modern buildings are explored through the frame of Kenneth Frampton's critical regionalism, in particular focusing on three important concepts: "dialectical expression," "place-form," and "sustainability." In this sense, this research will provide pioneering research in understanding the preservation of Korean modern architecture through a representative Western modern theory. In the early $20^{th}$ century, Korean modern architecture, which was built during the Japanese colonial period (1910-1945), could be interpreted as critical regionalism because it represented a dialog between the West and the East, in particular between Western modernism, Japanese modernity, and Korean tradition in the East Asian context. Understanding Korean modernism in this context of a cross-cultural perspective enables scholars to define both the origins and uniqueness of Korean modern architecture.

Spherical Robot for Planetary Explorations: An Approach to Educating Concepts of Mechatronics and Robotics to High School Students

  • Kim, Sooyoung;Kim, Seonje;Kim, Byungkyu;Sen, Soumen
    • Journal of Aerospace System Engineering
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    • v.14 no.2
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    • pp.36-43
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    • 2020
  • Many countries and international organizations have carried out rover missions to explore planetary surfaces. Accordingly, the demand for mechatronics education, which is closely related to building exploratory robots, is also steadily increasing. However, due to the complexity in understanding the background information needed for mechatronics, it is hard for pre-college students to study such process. In this study, we suggest an educational platform for mechatronics using a combined robot kit with a spherical robot and a smartphone application. To provide a visual understanding, the dynamic model of the robot is constructed while analyzing the error between actual driving and a simulation, and the educational algorithm of the game and a feedback method are proposed to improve the learning efficacy by considering the user's level of knowledge of mechatronics. We use this educational spherical robot to develop a curling game platform that can impart engineering education even when students lack significant knowledge.

A Grounded Theory Approach on Nurses' Experience with Workplace Bullying (간호사의 직장 내 괴롭힘 경험에 관한 근거이론 연구)

  • Kang, Jiyeon;Yun, Seonyoung
    • Journal of Korean Academy of Nursing
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    • v.46 no.2
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    • pp.226-237
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    • 2016
  • Purpose: The purpose of this qualitative study was to explore the workplace bullying experience of Korean nurses. Methods: Participants were twenty current or former hospital nurses who had experienced workplace bullying. Data were collected through focus group and individual in-depth interviews from February to May, 2015. Theoretical sampling method was applied to the point of theoretical saturation. Transcribed interview contents were analyzed using Corbin and Strauss's grounded theory method. Results: A total of 110 concepts, 48 sub-categories, and 17 categories were identified through the open coding process. As a result of axial coding based on the paradigm model, the central phenomenon of nurses' workplace bullying experience was revealed as 'teaching that has become bullying', and the core category was extracted as 'surviving in love-hate teaching' consisting of a four-step process: confronting reality, trial and error, relationship formation, and settlement. The relationship formation was considered to be the key phase to proceed to the positive settlement phase, and the participants utilized various strategies such as having an open mind, developing human relationships, understanding each other in this phase. Conclusion: The in-depth understanding of the workplace bullying experience has highlighted the importance of effective communication for cultivating desirable human relationships between nurses.

Elementary Teacher's Beliefs of Scientific Inquiry and Scientific Inquiry Teaching Method (초등학교 교사들의 과학적 탐구 및 지도방법에 관한 신념 연구)

  • Lee, Sang-Gyun
    • Journal of the Korean Society of Earth Science Education
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    • v.5 no.2
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    • pp.213-223
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    • 2012
  • This study explored practicing elementary school teacher's beliefs of scientific inquiry and scientific inquiry teaching methods. Defining teacher's beliefs as a broad construct, we tried to examine the teachers' understandings about the scientific inquiry and scientific inquiry teaching method. This study drew on interview data from 10 elementary teachers in busan and changwon area of korea. Conclusions of this study include; First, we found that elementary teacher's beliefs of inquiry were represented variously. And they considered that inquiry is the important goal of science education. They though that the goal of science education is development of Scientific inquiry skills, Scientific thinking skills, development of Creativity and problem solving ability, increasing interest about science, understanding of the basic concepts of science and apply of real-life. second, most of the teachers though that Scientific inquiry is scientists activities, they defined 'the process of creation of new knowledge', 'the process of deriving theory', 'solving process of intellectual curiosity', 'Problem-solving process'. third, they considered that teaching method of scientific inquiry is open inquiry activities. however, they thought that there are many difficulties to actually apply. Understanding teachers' beliefs has implications for both the enactment of inquiry teaching in the classroom as well as the uptake of new teaching behaviors during professional development, with enhanced outcomes for engaging students in Science.

Science Achievement: Synthesis of Current Conceptions in Major Reform Documents in the United States and Korea (과학 교육 개혁 운동에 관련된 보고서 분석을 통한 과학 성취 개념의 재정의)

  • 백성혜;이옥희
    • Journal of Korean Elementary Science Education
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    • v.18 no.2
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    • pp.1-19
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    • 1999
  • Based on the analysis of commonalities and differences in the views of science achievement in major reform documents in the United States and Korea, an aggregated view of science achievement is presented in this paper Science achievement is conceived of in terms of science content and science process. The components of science content include: (a) concepts and theories I n physical, life, and earth and space science;(b) science, mathematics, and technology;(c) science in personal and social perspectives;(d)history and nature of science;and (e) unifying themes. The components of science process include: (a) scientific understanding;(b) scientific investigation;(c) scientific communication; and (d) scientific habits of mind. The components of science process.cut across and intersect with the components of science content. The components of science achievement overlap and are related to one another. Despite such an overlap, understanding the rot e that each component plays provides insight into its unique contributions as well as its interactions with other components. A definition of science achievement and identification of its components based on major reform documents provides a guideline for science assessment as well a s science teaching and learning.

Abstract Representation of Events on Object-Oriented Programs (객체지향 프로그램에서 이벤트 추상화 표현)

  • Lim, Keun;Lee, Kyung-Hwan
    • The Transactions of the Korea Information Processing Society
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    • v.4 no.5
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    • pp.1257-1266
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    • 1997
  • The concepts of class, inheritance and information hicing and so on provide the great strengthes of object-oriented languages, but they also introduce diffculties in porfram analysis and understanding. Particulary, it is move difficult to umderstand the dyamic aspects than the static ones of object-oriented programs. The dyamicaspects can be understood by recognizing the event's reciprocal action among the classes. In this paper, it will be supplied to the reprecentation of event abstraction which is useful for understanding the object-oriented programs.And the clustering concept with the events will be applied to abstract the events. By clustering the events, user can get the information about function of the classes and the reteival of the class library.

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The Types of Analogy Generation Processes and the Perceptions of Analogy Generation on Saturated Solution of Fifth Grade Scientifically-gifted and General Elementary Students (초등학교 5학년 과학영재와 일반 학생들의 포화 용액 개념에 대한 비유 만들기 과정의 유형과 비유 만들기에 대한 인식)

  • Noh, Tae-Hee;Yang, Chan-Ho;Kang, Hun-Sik
    • Journal of Korean Elementary Science Education
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    • v.29 no.2
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    • pp.219-232
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    • 2010
  • In this study, we investigated and compared the types of analogy generation processes and the perceptions of analogy generation on saturated solution of fifth grade scientifically-gifted and general elementary students. After the instruction of self-generating analogies on 'saturated solution' concept for two classes, 12 scientifically-gifted and 8 general elementary students were interviewed to explore their analogy generation processes and the perceptions of the abilities required in the processes, the conditions of good analogies, and the advantages/disadvantages of analogy generation. The results revealed that their analogy generation processes were classified into three types. The scientifically-gifted students generated the analogies in more systematic and efficient ways and had better understanding of the important parts in the processes than the general elementary students. They also suggested more concrete and various ideas about the conditions of good analogies. Many scientifically-gifted and general elementary students thought that analogy generation would have positive influences on the developments of the cognitive aspects such as various higher-level thinking abilities and understanding of science concepts as well as the affective aspects such as science learning motivation and interest. Educational implications of these findings are discussed.

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