• 한국약용작물학회지
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• 제20권1호
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• pp.42-46
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• 2012

Soy isoflavones have been suggested to improve bone loss and lipid profile in postmenopausal women and ovariectomized rats. In present study, we investigated the hypothesis that consumption of soybean, mung bean, cowpea and azuki bean has a beneficial effect on lipid profile which associates with bone mass in ovariectomized rats. Forty two female Sprague-Dawley rats were either sham-operated (Sham) or surgically ovariectomized (OVX). Sham and OVX groups were fed a regular AIN-93M diet, but ovariectomized rats with soybean (OS), mung bean (OM), cowpea (OC) or adzuki bean (OA) were fed AIN-93M diet replacing 35% of corn starch with powdered OS, OM, OC or OA for 10 weeks. Total- and LDL-cholesterol concentrations were significantly lower in Sham and OC groups than other OVX groups. There was significant negative association between total cholesterol concentration and bone mineral density (BMD) of tibia in only OC group. In conclusion, total-cholesterol concentration was significantly and negatively correlated with BMD in rats consumed cowpea, suggesting that the reduced cholesterol concentration may have a beneficial effect on bone mass.

• Computers and Concrete
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• 제16권6호
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• pp.847-864
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• 2015

This study aimed to develop models of sulfate diffusion and ettringite content profile in cement paste for the predication of the damage behavior in cement paste subject to external sulfate. In the models, multiphase reaction equilibrium between ions in pore solution and solid calcium aluminates phases and the microstructure changes in different positions of cement paste were taken into account. The distributions of expansive volume strain and expansion stress in cement paste were calculated based on the ettringite content profile model. In addition, more sulfate diffusion tests and SEM analyses were determined to verify the reliability and veracity of the models. As the results shown, there was a good correlation between the numerical simulation results and experimental evidences. The results indicated that the water to cement ratio (w/c) had a significant influence on the diffusion of sulfate ions, ettringite concentration profile and expansion properties in cement paste specimens. The cracking points caused by ettringite growth in cement paste specimens were predicted through numerical methods. According to the simulation results, the fracture of cement paste would be accelerated when the specimens were prepared with higher w/c or when they were exposed to sulfate solution with higher concentration.

• 대한전자공학회논문지
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• 제22권6호
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• pp.58-62
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• 1985

이온 주입된 소형 MOSFET소자에 대한 해석적 문턱 전압 모델이 유도되었다. 일정한 도우핑 농도를 갖는 MOSFET에 적용되는 Yau 모델을 implanted channel구조와 bird's beat구조의 MOSFET에 대하여 적합한 형태로 수정하여 short channel 현상과 narrow width 현상을 정량적으로 설명하였다. Channel영역의 불순물 분포를 SUPREM 결과에서 2-step profile로 근사시켜 문턱 전압의 short channel model을 제안하였다. Weighting factor를 사용하여 bird's beat 영역의 불순물 분포를 고려함으로써 narrow width 현상을 성공적으로 설명하였다.

• Bulletin of the Korean Chemical Society
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• 제32권11호
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• pp.3967-3972
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• 2011

A whole body physiologically based pharmacokinetic (PBPK) model was applied to investigate absorption, distribution, and physiologic variations on pharmacokinetics of imatinib in human body. Previously published pharmacokinetic data of the drug after intravenous (i.v.) infusion and oral administration were simulated by the PBPK model. Oral dose absorption kinetics were analyzed by adopting a compartmental absorption and transit model in gut section. Tissue/plasma partition coefficients of drug after i.v. infusion were also used for oral administration. Sensitivity analysis of the PBPK model was carried out by taking parameters that were commonly subject to variation in human. Drug concentration in adipose tissue was found to be higher than those in other tissues, suggesting that adipose tissue plays a role as a storage tissue for the drug. Variations of metabolism in liver, body weight, and blood/plasma partition coefficient were found to be important factors affecting the plasma concentration profile of drug in human body.

• 패션비즈니스
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• 제20권6호
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• pp.66-78
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• 2016

Hygroscopic knitted cotton fabric was found to spontaneously absorb water showing a significantly wide concentration gradient in the absorption direction. A semi-empirical diffusion model was introduced to describe how the wicking behavior compared to the classical capillary model (Washburn's equation), which has been widely used in the textiles industry. The capillary sorption curve and the permeability coefficient, which are key variables for the model equations, were measured using an electronic balance. The concentration profile as a function of the wicking distance and the elapsed time was derived, based on the diffusion model. From the concentration profile, the wicking distance detectable by the human eye or a digital camera with the aid of an image-analysis system, could be described realistically as a function of the time. The classical capillary model could be modified by introducing the tortuous correction factor to match the diffusion model. Wicking models and data-processing techniques in the work could provide useful tools for objectively evaluating the textile's wicking performances.

• E2M - 전기 전자와 첨단 소재
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• 제10권9호
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• pp.881-888
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• 1997

This study demonstrats the profiles of phosphorus ions in silicon by MeV implantation(1∼3 MeV). Implanted profiles could be measured by SIMS(Cameca 4f) and compared with simulation results(TRIM program and analytical description method only using on Pearson function). The experimental result in the peak concentration region has a little bit deviation from simulation data. By RBS and Channeling measurements the defect distribution of implanted samples could be measured and spectrum are calibrated depth with RUMP simulation By XTEM measurement the thickness of defect zone also could be measured. Finally thermal annealing for the electrical activation of implanted ions carried out by RTA(rapid thermal annealing). The concentration-depth profiles after heat treatment was measured by SR(spreading resistance)-method.

• 대한기계학회논문집B
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• 제30권9호
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• pp.891-897
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• 2006

The SRS method is applied to a turbulent flame with radiation/turbulence interaction to invert the temperature and concentration profile. The flame is conditioned as optically thin per each fluctuation length and the flame spectral intensity is measured for inversion. From inversion result, we find that SRS can successfully invert the coupled temperature/concentration fluctuation amplitudes. For two cases of experiments, inverted values are within approximately 1% over the full range of fluctuation amplitude. However, SRS cannot find the detailed local fluctuation parameters such as pattern and phase, etc. as far as they do not affect the resulting radiation intensity. Important available parameters are the mean temperature and the temperature fluctuation amplitude. The radiation/turbulence interaction effect is verified to play an important role in the radiation.

• Steel and Composite Structures
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• 제38권1호
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• pp.33-45
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• 2021

The Runge-Kutta method of 6th-order has been employed in this paper to analyze the flow of Casson nanofluid along permeable exponentially stretching cylinder. The modeled PDEs are changed into nonlinear ODEs through appropriate nonlinear transformations. The aim of the paper is to investigate the effects of different parameters such as Casson fluid parameter, slip parameter, suction parameter, Prandtl number, Lewis number, Brownian motion parameter, and thermophoresis parameter, with the variation of mass concentration profile. Numerical results are attained using a renowned numerical scheme shooting technique and for the authenticity of present methodlogy, the results are verified with earlier open text.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2000년도 하계학술대회 논문집
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• pp.55-58
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• 2000

SiGe heterojuction bipolar transistors (HBT) have been studied and applied for advanced high speed integrated circuits. Device characteristics of SiGe HBT depending on the Ge profile of the transistor base region have been analysed using a device simulator, ATLAS/BLAZE. The models and parameters have been calibrated to the measured characteristics of the device, having a trapeziodal base profile, including the cut-off frequency of 45GHz and the dc current gain of 200. The Ge concentration which increases linearly, exponentially, or root-functionally from the emitter-base junction to the base-collector junction, has been tried to find out the influence on the device characteristics. The cut-off frequency and gain rather strongly depends on the exponential and root-functional Ge base profiles, respectively.

• Environmental Analysis Health and Toxicology
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• 제24권3호
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• pp.251-259
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• 2009

This study was conducted to measure the concentration of PCBs in pine needles and soil in urban (Seoul, many artificial sources of PCBs), semi-rural (Anseong, small town located below Seoul in wind direction) and rural areas (Jincheon, rarely artificial sources of PCBs) in which the artificial production amount of PCBs are different. The total PCBs concentrations in pine needles, which did not show big difference in three sampling sites, were 107.5 pg/g (urban), 94.8 pg/g (semi-rural) and 78.8 pg/g (rural) respectively. The low chlorinated PCBs were major component in pine needles and the PCBs congener concentration profile of each sampling area were similar each other, and the octanol-air partitioning coefficient, Koa, highly correlated with the PCBs concentrations in pine needles. The total PCBs concentrations in soil which did show big difference in three sampling sites, were 830.0 pg/g (urban), 314.1 pg/g (semi-rural) and 136.5 pg/g (rural) respectively. The high chlorinated PCBs were major component in soil and the PCBs congener concentration profile of each sampling area were similar each other. There was no similarity between the PCBs concentration of pine needles and those of soil at each site, because of the different mechanism of deposition and volatilization processes of PCBs. The total PCBs concentrations of 2009 became 12.9 times lower than those of 2001. The reduce rate of PCB 28 was the greatest.